Clinical trials: GASTROINTESTINAL NEOPLASMS
Hepatocellular Carcinoma
Long-term Management of Patients With Ruptured HCC
The main objective of this work is to evaluate the prevalence and results of specific management of HCC after spontaneous rupture, since the arrival of sorafenib in 2008.
- Trial name
- NCT06505291
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Neoplasm, Colorectal, Neoplasm, Breast
Development, Implementation and Evaluation of an Individual Decision Aid in Swedish Cancer Screening Programs
Background: Sweden has a long tradition of organized national population-based screening programs. Participation rates differ between programs and regions, are relatively high in some groups, but lower in other.
- Conditions
- Neoplasm, Colorectal, Neoplasm, Breast, Neoplasm, Ovarian
- Trial name
- BESTa (NCT05512260)
- Testing
- Individual decision aid (iDA)
- Where
- Sweden
- Volunteers
- healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Gastric Cancer
Early Onset and Familial Gastric Cancer Registry
The purpose of this study is to establish a gastric cancer registry. A registry is a database of information. With the registry, we can learn more about the genetic causes of gastric cancer in order to develop better methods of…
- Trial name
- NCT00582257
- Testing
- questionnaires
- Where
- 10 sites in United States, Nigeria
- Volunteers
- 971 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Hepatocellular Carcinoma
Phase Ⅲ Randomized Trial in Postoperative Hepatocellular Carcinoma
OBJECTIVES 1. To investigate whether adjuvant IFN-α therapy can delay or reduce the 2-5 years recurrence rate in curatively resected HCC . 2.
- Trial name
- NCT00149565
- Testing
- IFN-α2b
- Where
- Taiwan
- Volunteers
- 268 people, healthy volunteers welcome
- Sponsor
- National Health Research Institutes, Taiwan
Hepatocellular Carcinoma
A Clinical Study of GP73 as a Hepatocellular Carcinoma (HCC) Tumor Mark
The aims of this study were divided into three parts: 1. To evaluate the sensitivity and specificity of GP73 for the diagnosis of hepatitis B related HCC. Established the standard of GP73 in normal people. 2.
- Trial name
- NCT00902902
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Liver Cancer
Effect of Smoked Plum and Chewing Gum on Postoperative Bowel Function Following Hepatic Resection
Every patient undergoing surgery in the abdomen, such as hepatic resection, will experience temporary paralysis of bowel function.
- Trial name
- SP/GC-HCC (NCT02649153)
- Testing
- smoked plum, gum chewing
- Where
- China
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Guangxi Medical University
Early Esophageal Cancer or Precancerous Lesions Treated With Endoscopic Resection
The Cohort Study of Early Esophageal Cancer or Precancerous Lesions Treated With Endoscopic Resection
Endoscopic Submucosal Dissection (ESD) is currently the main method of treatment of early esophageal cancer and precancerous lesions.
- Trial name
- NCT03377972
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Shanghai Zhongshan Hospital
Peritoneal Neoplasms
Quality of Life Study for Pediatric and Adult Patients Undergoing Hyperthermic Peritoneal Perfusion With Cisplatin
Objectives: The overall objective of this prospective study is to provide a descriptive analysis of the quality of life of cancer patients enrolled on M. D.
- Trial name
- NCT00502177
- Testing
- Questionnaire
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Colon Cancer, Colorectal Cancer
Does Genetic Susceptibility for Bleeding Affect Quantitative Faecal Immunochemical Test (qFIT) Results?
Quantitative faecal immunochemical testing (qFIT) is used to test for blood within faeces that cannot always be visible. The presence of blood in the stool has been shown to be a finding where there may be a problem within the…
- Trial name
- NCT05329870
- Testing
- SNP array
- Where
- United Kingdom
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Edinburgh
Malignant Tumors of Digestive Tract
Multi-omics Study of Tongue Coating in Malignant Tumors of Digestive Tract
This is a prospective, multi-center, observational cohort study and seeks to enroll 20000 patients with one malignant tumor of digestive tract or healthy individual.
- Trial name
- NCT05794841
- Testing
- Tongue coating sample collection and multi-omics analysis
- Where
- China
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- Zhejiang Cancer Hospital
Cancer Screening, Lung Cancer
Precision Navigation to Improve Community Cancer Screening Participation
This study will evaluate whether a precision navigation intervention can help community residents at high risk for cancer complete recommended cancer screening.
- Conditions
- Cancer Screening, Lung Cancer, Breast Cancer, Colorectal Cancer
- Trial name
- NCT07676383
- Testing
- Precision Navigation Intervention, Usual Health Education
- Where
- 3 sites in China
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Hunan Cancer Hospital
Colon Cancer
Impact of a Mailed Educational Reminder on Fecal Occult Blood Testing (FOBT): A Randomized Controlled Trial
The purpose of our randomized controlled trial is to determine whether mailed educational reminders would increase fecal occult blood test (FOBT) card return rates and, therefore, improve patient compliance with colonrectal…
- Trial name
- NCT00534053
- Testing
- Mailed Educational Reminder
- Where
- United States
- Volunteers
- 775 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Breast Carcinoma, Colorectal Carcinoma
Incorporating ePrognosis for the Encouragement of Smarter Screening for Breast and Colorectal Cancer in Older Adults
This clinical trial assesses the feasibility and acceptability of a smarter screening intervention for breast and colorectal cancer in older adults.
- Trial name
- NCT05021172
- Testing
- Best Practice, Informational Intervention, Questionnaire Administration
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Ampulla of Vater Carcinoma, Appendix Carcinoma
Studying the PAGODA Algorithm for Chemotherapy Dose Changes to Prevent Unplanned Treatment Delays
This clinical trial is being done to learn whether using the proactive, graduated dose modification algorithm for leucovorin, 5-fluorouracil (5-FU), and oxaliplatin (FOLFOX) (PAGODA) algorithm to guide chemotherapy dosing for the…
- Conditions
- Ampulla of Vater Carcinoma, Appendix Carcinoma, Carcinoma of Unknown Primary With Gastrointestinal Profile, Colon Carcinoma
- Trial name
- NCT07283939
- Testing
- PAGODA algorithm, Oxaliplatin, Folinic Acid
- Where
- 398 sites in United States, Guam and 1 more
- Volunteers
- 420 people, healthy volunteers welcome
- Sponsor
- Alliance for Clinical Trials in Oncology
Cancer Breast, Colon Cancer
The Effect of Acceptance and Commitment Approach-Based Psychoeducation in Cancer Survivors
The study is planned to be conducted in a randomised controlled experimental design in accordance with CONSORT. The study is planned to be conducted between September 2025 and December 2026 at X Hospital with individuals who have…
- Conditions
- Cancer Breast, Colon Cancer, Cancer Survivors
- Trial name
- NCT07205965
- Testing
- Experimental Group
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Dokuz Eylul University
Colonic Neoplasms
Imaging Colo-rectal Cancer Using a Two Step Antibody Technique in Nuclear Imaging
The purpose of this study is to test the safety of the peptide and antibody and at the same time evaluate the tumor imaging of a two step antibody technique in nuclear imaging.
- Trial name
- NCT00185081
- Testing
- Indium labeled IMP-205xm734
- Where
- Netherlands
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Pancreatic Cancer, Pancreatic Ductal Adenocarcinoma
AI-powered Early Detection for Pancreatic Cancer Via Non-contrast CT in Opportunistic Screening Cohort
Pancreatic ductal adenocarcinoma (PDAC) remains a therapeutic challenge with 5-year survival rates of 13%, primarily attributable to advanced-stage diagnosis (AJCC Stage III/IV in >80% of cases).
- Conditions
- Pancreatic Cancer, Pancreatic Ductal Adenocarcinoma, Pancreatic Intraepithelial Neoplasias, Intraductal Papillary Mucinous Neoplasm
- Trial name
- AI-PANC (NCT06638866)
- Testing
- PDAC, Pancreatic precursor lesions
- Where
- 3 sites in China
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital
Bowel Cancer, Colon Cancer
Serial SMS Reminders and an Opt-out Mailed FIT Kits to Improve Colorectal Screening Participation: A Single Center RCT
This pilot study is a 2-armed randomized controlled trial assessing the impact of a multimodal approach on colorectal cancer screening participation rates in a Federally Qualified Health Center.
- Trial name
- NCT03479645
- Testing
- Serial text messages and mailed FIT kit
- Where
- United States
- Volunteers
- 440 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Hepatocellular Carcinoma
Simo Decoction and Gum Chewing for Bowel Activity
Abdominal surgery, including hepatic resection for hepatocellular carcinoma (HCC), is inevitably followed by an episode of gastrointestinal hypomotility.
- Trial name
- SD/GC-HCC (NCT02438436)
- Testing
- simo decoction, gum chewing
- Where
- China
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Guangxi Medical University
Colorectal Cancer
The Northern-European Initiative on Colorectal Cancer
Colorectal cancer (CRC) is a major burden in western countries. The disease develops from precursor lesions during a long time-interval.
- Trial name
- NordICC (NCT00883792)
- Testing
- Colonoscopy
- Where
- 7 sites in United States, Iceland and 4 more
- Volunteers
- 95,000 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
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