Clinical trials: GDM
Hyperemesis; Gravidarum, With Dehydration, Gestational Diabetes
Hyperemesis Gravidarum and 75 Gram Oral Glucose Tolerance Test
Hyperemesis gravidarum (HEG) is not only nausea and vomiting of pregnancy, but it is also a clinical syndrome including endocrine and metabolic complications.
- Trial name
- NCT02963753
- Volunteers
- 560 people, healthy volunteers welcome
- Sponsor
- Kayseri Education and Research Hospital
Pregnancy Related, Diabetes
Exercise Timing and Gestational Diabetes
The aim of this study is to understand if the timing of exercise around food intake can help improve blood sugar management in pregnant individuals with diabetes.
- Conditions
- Pregnancy Related, Diabetes, Diabete Mellitus, Type 2 Diabetes
- Trial name
- NCT05256615
- Testing
- 30-minute walking intervention, 10-minute
- Where
- Canada
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Mobile Health Apps, Lifestyle Intervention
Effectiveness of an AI-Enabled Mobile Intervention on Lifestyle Behaviors and Maternal-Infant Health
The goal of this pragmatic randomized controlled trial is to evaluate the effectiveness of an AI-enabled mobile health management application ("Better Pregnancy" app), grounded in the Theory of Planned Behavior, in preventing…
- Conditions
- Mobile Health Apps, Lifestyle Intervention, Prevention, Multi-component Based Behavioral Intervention
- Trial name
- NCT07582068
- Testing
- Multi-component lifestyle intervention
- Where
- China
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Fangbiao Tao
Cardiovascular Diseases
Continuation of the nuMoM2b Heart Health Study
Cardiovascular disease (CVD) is the leading cause of mortality and morbidity in U.S. women at all ages, and large knowledge gaps exist in CVD predictive and preventative strategies for women.
- Trial name
- nuMoM2b-HHS2 (NCT05472597)
- Where
- 14 sites in United States
- Volunteers
- 4,048 people, healthy volunteers welcome
- Sponsor
- RTI International
Birth-weight
Efficacy of Behavioral Therapy and Exercise in Gestational Diabetes Mellitus (GDM)
The purpose of the study is to test whether four lifestyle intervention programs (diet alone; diet and behavioral therapy, diet and exercise, diet and behavioral therapy and exercise), delivered to women with GDM during 24-26…
- Trial name
- NCT01506310
- Testing
- Behavioral therapy, Exercise, Behavioral therapy and exercise
- Where
- Italy
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Turin, Italy
Gestatiaonl Diabetes Mellitus
The Role of Progesterone Membrane Receptors in the Development of Gestational Diabetes Mellitus
The aim of this study is to investigate the potential roles of PGRMC1, PGRMC2, and PAQR family membrane progesterone receptors in the pathophysiology of gestational diabetes mellitus by comparing their expression levels in…
- Trial name
- NCT07750431
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Samsun University
Gestational Diabetes, Hyperglycemia
Early Investigation of Glucose Monitoring After Gestational Diabetes Pilot
One third of women with gestational diabetes (GDM), diabetes diagnosed during pregnancy, have abnormal glucose levels within 3 years after pregnancy, but follow up is low.
- Trial name
- ENGAGED (NCT06184373)
- Testing
- Continuous glucose monitor, Oral Glucose Tolerance Test, Hemoglobin A1c
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Gestational Diabetes Mellitus in Pregnancy
Long-term Effects of Flash Glucose Monitoring System in Patients With Gestational Diabetes
The purpose of this study is to report the glycemic control effect and clinical safety and effectiveness of mother and fetus when using a continuous glucose monitoring system (CGM) [Freestyle Libre] for a long period of time…
- Trial name
- GDMLIBRE (NCT06031987)
- Testing
- CareSens N (iSENS), Freestyle Libre (Abbott)
- Where
- South Korea
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Kangbuk Samsung Hospital
Gestational Diabetes Mellitus (GDM), Postpartum Women
The Impact of Gestational Diabetes Mellitus on Cerebral Blood Flow and Cerebrovascular Function After Pregnancy
Gestational Diabetes Mellitus (GDM) currently affects approximately 14% of all pregnancies worldwide. Importantly, the health-related consequences of GDM extend well beyond pregnancy, such that women with a history of GDM have a…
- Conditions
- Gestational Diabetes Mellitus (GDM), Postpartum Women, Uncomplicated Pregnancy
- Trial name
- NCT06911372
- Testing
- Intradermal Microdialysis, Brain Blood Flow Tests, Local Heating
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Anna Stanhewicz, PhD
Gestational Diabetes, High Blood Pressure
Social Deprivation and Pregnancy
Social deprivation during pregnancy is associated to adverse perinatal outcomes. However, prenatal screening of social deprivation by reliable measurement is not performed.
- Conditions
- Gestational Diabetes, High Blood Pressure, Prematurity, Fetal Growth Restriction
- Trial name
- NCT03121196
- Testing
- Epices score
- Where
- France
- Volunteers
- 615 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Gestational Diabetes, Pregestational Diabetes
Maternal Diabetes in Newborns With Hearing Loss
This study aims to investigate the presence and characteristics of maternal diabetes as a risk factor in newborns with hearing loss. Hearing loss is one of the most common congenital anomalies among newborns.
- Conditions
- Gestational Diabetes, Pregestational Diabetes, Hearing Loss
- Trial name
- GDM (NCT05152589)
- Testing
- hearing test
- Where
- Turkey (Türkiye)
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Pregnancy, Stress
Effects of Stress on Glucose Tolerance During Pregnancy
The objective of the study is to investigate the effect of stress on glucose tolerance during pregnancy. The main objectives of the study are to investigate if various measures of stress (stressful life events, the perceived…
- Conditions
- Pregnancy, Stress, Gestational Diabetes
- Trial name
- NCT01707784
- Where
- Switzerland
- Volunteers
- 203 people, healthy volunteers welcome
- Sponsor
- University of Lausanne Hospitals
Gestational Diabetes Mellitus
The Impact of Liraglutide on Glucose Tolerance and the Risk of Type 2 Diabetes in Women With Previous Pregnancy-induced Diabetes
It is well-known that women with previous gestational diabetes mellitus are in risk of developing type 2 diabetes later in life; approximately half of the women develop overt type 2 diabetes within the first 10 years after…
- Trial name
- NCT01795248
- Testing
- Liraglutide
- Where
- Denmark
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Tina Vilsboll
Gestational Diabetes
Effects of Antenatal Exercises on Clinical Outcomes in Pregnant Females With Gestational Diabetes Mellitus
Gestational diabetes mellitus (GDM) GDM is the most common complication that affects the health of the child and mother during pregnancy.
- Trial name
- NCT04859348
- Testing
- routine physical therapy, routine physical therapy and antenatal exercises
- Where
- Pakistan
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Lahore
Gestational Diabetes Mellitus, Neurodevelopmental Disorders
n-3 PUFAs, Irisin and Maternal Glucose Metabolism From Pregnancy to Postpartum
This study aims to investigate the associations of maternal nutritional status during pregnancy and postpartum periods with postpartum abnormal glucose metabolism in Guangzhou pregnant women.
- Conditions
- Gestational Diabetes Mellitus, Neurodevelopmental Disorders, Postpartum Abnormal Glucose Metabolism, Child Growth and Development
- Trial name
- NCT03023293
- Testing
- No intervention
- Where
- China
- Volunteers
- 1,122 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Gestational Diabetes
Associations of Plasma Vanadium Concentrations With Gestational Diabetes Mellitus
Background: Vanadium compounds have been shown to exert insulin-mimetic effects and thereby control glucose homeostasis. However, studies regarding the levels of vanadium and gestational diabetes mellitus (GDM) are limited and…
- Trial name
- NCT05267457
- Testing
- Plasma vanadium concentration
- Volunteers
- 504 people, healthy volunteers welcome
- Sponsor
- Liegang Liu
Gestational Diabetes, GDM
The MalaYsian GestatiOnal Diabetes and Prevention of DiabetES Study
Gestational diabetes mellitus (GDM) is an increasingly common condition of pregnancy and is associated with adverse foetal, infant, and maternal outcomes.
- Conditions
- Gestational Diabetes, GDM, Pregnancy-Induced Diabetes
- Trial name
- MyGODDESS (NCT05204706)
- Testing
- MyManis app
- Where
- 3 sites in Malaysia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universiti Putra Malaysia
Gestational Diabetes, Hyperglycemia
Gestational Metabolic Abnormalities and Maternal and Infant Nutrition and Health
Childhood obesity is on the rise and is a major risk factor for type 2 diabetes later in life. Recent evidence indicates that abnormalities that increase risk for diabetes may be initiated early in infancy.
- Conditions
- Gestational Diabetes, Hyperglycemia, Insulin Resistance, Obesity
- Trial name
- NCT01405547
- Where
- Canada
- Volunteers
- 271 people, healthy volunteers welcome
- Sponsor
- Anthony Hanley
Gestational Diabetes Mellitus in Pregnancy, Glucose Intolerance During Pregnancy
Effects of a Non-nutritive Sweetener Reduction Intervention in Pregnancy and Lactation on Maternal and Infant Outcomes
The effects of consuming non-nutritive sweeteners (NNS) during pregnancy and lactation on infant obesity and cardiometabolic disease risk are not well understood.
- Conditions
- Gestational Diabetes Mellitus in Pregnancy, Glucose Intolerance During Pregnancy, Non-nutritive Sweeteners Consumption in Pregnancy and/or Lactation
- Trial name
- NCT06548828
- Testing
- NNS Restriction Intervention, Control Intervention
- Where
- United States
- Volunteers
- 324 people, healthy volunteers welcome
- Sponsor
- George Washington University
Diabetes, Gestational
DIAgnosing GDM usiNg Oral Sugar InStead
The purpose of this study is to compare the positive and negative effects of Dex4® tablets, as an alternative form of fast acting carbohydrate, compared to the current standard diagnostic test, glucose beverage.
- Trial name
- DIAGNOSIS (NCT05115188)
- Testing
- Dex4/ dextrose, Glucose beverage
- Where
- Canada
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre