Clinical trials: GI-bleeding
Gastrointestinal Bleeding, Acute Coronary Syndrome
Factors Contributing To Cardiovascular Morbidity and Mortality in Patients With Gastrointestinal Bleeding
The rate of complication and death of patients with acute digestive tract bleeding is increased in the setting of acute coronary heart disease.
- Trial name
- NCT00401908
- Where
- United States
- Sponsor
- Maimonides Medical Center
Nurse
Effectiveness of Teaching Program for the Management of Upper GI Bleeding
A study to assess the effectiveness of teaching program for the management of upper GI bleeding in terms of gain in nurses' practice and knowledge related to management of upper GI bleeding among chronic liver disease patients…
- Trial name
- NCT05207410
- Where
- India
- Volunteers
- 20 people
- Sponsor
- Institute of Liver and Biliary Sciences, India
Radiation Proctitis, Gastrointestinal Hemorrhage
A Study of Chlorophyllin or Placebo With Standard Treatment for Late Radiation Induced Luminal Gastrointestinal Tract Bleeding
This multicenter, randomized, double-blind, placebo-controlled Phase III clinical trial will evaluate whether oral sodium copper chlorophyllin (CHL) is effective and safe for treating late radiation-induced gastrointestinal (GI)…
- Conditions
- Radiation Proctitis, Gastrointestinal Hemorrhage, Radiation Injuries
- Trial name
- NCT07837713
- Testing
- Chlorophyllin, Sodium Copper Complex
- Where
- India
- Volunteers
- 200 people
- Sponsor
- Tata Memorial Centre
Gastrointestinal Hemorrhage, Vascular Malformation
Efficacy Study of Thalidomide in Gastrointestinal Vascular Malformation Related Bleeding
Background: Repeated bleeding from gastrointestinal vascular malformations remains to be a major therapeutic challenge. Methods: The investigators performed a randomised, double-blind, placebo-controlled, single centre study to…
- Trial name
- NCT02754960
- Testing
- Thalidomide
- Where
- China
- Volunteers
- healthy volunteers welcome
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Gastrointestinal Hemorrhage
Early Colonoscopy for Lower Gastrointestinal (GI) Bleeding
Study hypothesis is that performing early colonoscopy in patients who present to the hospital with lower GI bleeding improves their outcome.
- Trial name
- NCT01031342
- Testing
- Early colonoscopy, Elective colonoscopy
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- University of Southern California
Rectal Bleeding
Diagnostic Outcomes of Patients Presenting With Per Rectal Bleed in Surgical Departments of Services Hospital Lahore
It is a cross sectional study in which investigators will be recruiting patients of any sex above 12 years of age who will present to surgical outdoor with per rectal bleed.
- Trial name
- NCT03594942
- Testing
- procto sigmoidoscopy and biopsy if required
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- Services Hospital, Lahore
Re-bleeding in NVUGIB
Survey of Non-Variceal Upper Gastro Intestinal Bleeding in Vietnamese Patients
The main aim of the study is to describes the outcomes of patients with Upper Gastrointestinal Bleed (UGIB) in a real-life setting.
- Trial name
- NIS-PUB (NCT01292915)
- Where
- 3 sites in Vietnam
- Volunteers
- 1,044 people
- Sponsor
- AstraZeneca
Peptic Ulcer, Hemorrhage
Different Dose of Intravenous Omeprazole to Treat Bleeding Ulcer With Adherent Clot
The investigators will include those patients with adherent clot on gastric or duodenal ulcers after endoscopic confirmation After receiving well explanation and giving written consent, they are enrolled and will be allocated to…
- Trial name
- NCT02536989
- Testing
- omeprazole
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- Far Eastern Memorial Hospital
Bleeding Ugi
PillSense for Suspected Upper Gastrointestinal Bleeding
This study aims to evaluate the efficacy and safety of a novel blood sensing capsule (PillSense), to help emergency doctors better evaluate if patients have active upper digestive tract bleeding, to determine if they can be…
- Trial name
- BLEED (NCT06500468)
- Testing
- PillSense System
- Where
- Singapore
- Volunteers
- 84 people
- Sponsor
- Tan Tock Seng Hospital
Gastric Polyp, Gastric Neoplasm
Tranexamic Acid During Upper GI Endoscopic Resection Procedures
Endoscopic resection of gastrointestinal lesions may prevent cancer. However, resection is associated with adverse events such as bleeding.
- Conditions
- Gastric Polyp, Gastric Neoplasm, Duodenal Neoplasms, Esophageal Neoplasms
- Trial name
- NCT05688020
- Testing
- Tranexamic acid, Epinephrine injection
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- Assaf-Harofeh Medical Center
Obscure Gastrointestinal Bleeding (Occult or Overt)
Trial of Wireless Capsule Endoscopy in the Evaluation of Obscure Gastrointestinal Bleeding
This study compares wireless capsule endoscopy (patients swallow a pill-size camera that sends pictures of the intestine to a recorder worn on their belt) to an x-ray study (called dedicated small bowel contrast radiography) in…
- Trial name
- NCT01006824
- Testing
- Capsule endoscopy, Dedicated small bowel contrast radiography
- Where
- United States
- Volunteers
- 136 people
- Sponsor
- University of Southern California
Esophageal Varices
Upper Endoscopy in Cirrhotic Patients With Upper Gastrointestinal Bleeding
Liver cirrhosis is a common diffuse and persistent liver disease often accompanied by portal hypertension, liver failure, upper gastrointestinal bleeding (UGIB), and other complications.
- Trial name
- Varices (NCT06214234)
- Testing
- Band ligation
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Radiotherapy, Radiation Proctitis
Dietary Supplements to Treat Radiation-Induced Rectal Injury
This clinical study is a prospective, single-arm, single-center trial aimed at assessing the safety and efficacy of tributyrin (TB) as dietary supplements in the treatment of chronic radiation-induced rectal injury (RRI).
- Trial name
- NCT06776016
- Testing
- Butyrate
- Where
- China
- Volunteers
- 33 people
- Sponsor
- Sixth Affiliated Hospital, Sun Yat-sen University
Bloody Stool, Necrotizing Enterocolitis
a Clinical Risk Score to Predict Bloody Stool in Neonates
Bloody stool is a main focus in non-neonatal intensive care unit ward, and it is one of the risk factors in neonates with subsequent necrotizing enterocolitis(NEC) and usually lead to longed duration of hospitalization.
- Trial name
- NCT05055817
- Testing
- bloody stool group, non-bloody stool group
- Where
- China
- Sponsor
- Daping Hospital and the Research Institute of Surgery of the Third Military Medical University
Upper Gastrointestinal Bleeding
Thoracic Ultrasound on Upper Gastrointestinal Bleeding (ECOBLEDSTUDY)
Upper Gastrointestinal bleeding (UGIB) is a medical emergency and the most common cause of hospitalization associated with digestive disease. Proper initial resuscitation is the first step in the management of UGIB patients.
- Trial name
- NCT03944148
- Where
- Mexico
- Volunteers
- 110 people
- Sponsor
- Hospital Universitario Dr. Jose E. Gonzalez
Gastrointestinal Diseases
An Observer Blinded Comparison of MACE and Conventional Upper Gastrointestinal Endoscopy in Upper GI Bleeding
Gastroscopy (OGD) is a useful test for investigating a variety of suspected upper GI disorders. But it is uncomfortable for patients and incurs the risk of intubation and sedation, plus a large proportion of procedures reveal…
- Trial name
- MACE (NCT02690376)
- Testing
- Magnetic Assisted Capsule Endoscopy
- Where
- 2 sites in United Kingdom
- Volunteers
- 23 people
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Roux-en-y Anastomosis Site, Marginal Ulcer
Marginal Ulcer Healing With Low-Thermal Argon Plasma Endoscopic Treatment
The objective of the study is to investigate the treatment of marginal ulcers with Low Thermal plasma in an endoscopic setting. By a treatment of the ulcerated areas with argon plasma with low power settings (~ 1 W) we…
- Conditions
- Roux-en-y Anastomosis Site, Marginal Ulcer, Marginal Ulcer (Peptic) or Erosion, Ulcer
- Trial name
- AMULET (NCT06543316)
- Testing
- Low Thermal Plasma (LTP) Treatment, Standard of Care Ulcer Treatment (typically PPI Administration)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Christopher C. Thompson, MD, MSc
Upper Gastrointestinal Bleeding
Gastric CLEANsing by Intravenous AZithromycin in Urgent Endoscopy
This study will test the hypothesis that azythromycin is efficient and safe in cleansing the upper gastrointestinal tract for endoscopic examination in the case of acute bleeding.
- Trial name
- CLEAN-AZ (NCT06077916)
- Testing
- Azithromycin, Saline solution
- Where
- Romania
- Volunteers
- 224 people
- Sponsor
- Clinical Hospital Colentina
Pancreatic Ductal Adenocarcinoma
Prevention of Upper Gastrointestinal Hemorrhage Using Albis® in the Patients of Locally Advanced Pancreatic Cancer Who Underwent Concurrent Chemoradiotherapy
Pancreatic ductal adenocarcinoma is the fourth cause of death in the Western world. About 40% of pancreatic cancer patients were diagnosed as locally advanced unresectable status without distant metastasis.
- Trial name
- NCT02570529
- Testing
- Albis®
- Sponsor
- Yonsei University
Acute Coronary Syndromes (ACS), Coronary Artery Disease (CAD)
Fexuprazan for Prevention of Upper Gastrointestinal Bleeding in High Bleeding Risk Patients Receiving Dual Antiplatelet Therapy
This study evaluates whether fexuprazan is effective in preventing upper gastrointestinal bleeding and related upper gastrointestinal clinical events in high bleeding risk patients who require dual antiplatelet therapy after…
- Trial name
- SAINT-FEXUDAPT (NCT07479056)
- Testing
- Fexuprazan 40mg, Lansoprazole 30mg
- Where
- South Korea
- Volunteers
- 200 people
- Sponsor
- SUK MIN SEO