Clinical trials: Gallbladder
Calculous Cholecystitis, Antibiotic Resistant Infection
Cholecystitis From a Microbiological and Histopathological Perspective
The aim of this project is to investigate the presence of bacteria in the gallbladder wall and the bile in patients undergoing cholecystectomy, to determine if the standard empirical antibiotic treatment used currently is…
- Conditions
- Calculous Cholecystitis, Antibiotic Resistant Infection, Gallbladder Inflammation
- Trial name
- NCT05712733
- Testing
- Microbiological and histopathological investigation of bile and gallbladder wall specimens.
- Where
- Denmark
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Organkirurgisk afdeling, sygehus lillebælt, Kolding
Cholelithiasis, Gall Bladder Disease
3D HD Versus 2D HD in Cholecystectomy
The aim of this study is to compare 3D-laparoscopy versus 2D-laparoscopy with the use of HD resolution in cholecystectomy in terms of error rating, performance time and subjective assessment.
- Trial name
- NCT02396927
- Testing
- 3D HD laparoscopy, 2D HD laparoscopy
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Herlev Hospital
Cerebral Hypoperfusion, Cerebral Occlusion
Evaluation of Cerebral Blood Flow and Cerebral Oxygenation With Transcranial Doppler and NIRS in Laparoscopic Cholecystectomy Cases
The goal of this clinical trial is to test intracranial blood flow and cerebral oxygenisation changes in patients who have pneumoperitoneum in laparoscopic cholecystectomy procedure.
- Conditions
- Cerebral Hypoperfusion, Cerebral Occlusion, Cholecystitis; Gallstone, Cholecystitis/Cholelithiasis
- Trial name
- NIRS L/C (NCT06036498)
- Testing
- Near Infrared Spectrophotometry Device, Transcranial Doppler Ultrasonography
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Uludag University
Fasting, Chronic Disease
A Retrospective and Prospective Cohort Study of the 21-day Fasting-like Diet in Patients With Metabolic and Autoimmune Diseases
Effectiveness of fasting or fasting-mimicking diet has been proved an effective approach to treat metabolic and autoimmune diseases in mice.
- Conditions
- Fasting, Chronic Disease, Autoimmune Diseases, Metabolic Disease
- Trial name
- NCT03193177
- Testing
- the 21-day fasting-like diet
- Where
- China
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Tsinghua University
Hemodynamics Instability, Post Operative Pain
Evaluating Perioperative Outcomes: Dexmedetomidine vs Lignocaine in Laparoscopic Chlolecystectomy
Nowadays laparoscopic surgery is the first choice for many surgeries. Such surgeries have revolutionized the surgical practice and has markedly reduced the incidence of intraoperative and postoperative complications.
- Conditions
- Hemodynamics Instability, Post Operative Pain, Gastrointestinal Dysfunction, Cholecystitis
- Trial name
- NCT06740903
- Testing
- inj. dexmedetomidine infusion @ 0.2-0.4 μg/kg/h, inj. lignocaine infusion @1-2 mg/kg/h
- Where
- Pakistan
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Sahiwal medical college sahiwal
Metastatic Cancer, Foregut Carcinoid Tumor
Study Comparing Standard of Care Chemotherapy With/ Without Sequential Cytoreductive Surgery for Patients With Metastatic Foregut Cancer and Undetectable Circulating Tumor-Deoxyribose Nucleic Acid Levels
This study is designed for participants who have cancer of the upper gastrointestinal (GI) tract such as cancer of the esophagus, stomach, duodenum (the initial portion of your small intestine), pancreas, bile duct…
- Conditions
- Metastatic Cancer, Foregut Carcinoid Tumor, Gastric Adenocarcinoma, Gallbladder Adenocarcinoma
- Trial name
- NCT04931420
- Testing
- Standard of Care Chemotherapy, Video-Assisted Thoracic Surgery (VATS), Lobectomy
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Chicago
Choledocholithiasis
Papillary Balloon Dilation Versus Intraductal Lithotripsy
Our aim is to compare the efficacy, safety, procedural time required, and costs of a strategy initially employing cholangioscopy guided intraductal lithotripsy (laser/electrohydraulic lithtripsy (EHL)) versus a strategy initially…
- Trial name
- NCT03536247
- Testing
- Initial therapy with papillary balloon dilation, Initial therapy with intraductal lithotripsy
- Where
- 2 sites in United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Hyperemesis Gravidarum, Pregnancy Related
Gallbladder Functions & Serum Cholecystokinin Levels in Women Diagnosed With Hyperemesis Gravidarum
This study evaluates the gallbladder functions and serum cholecystokinin levels in pregnant women diagnosed with hyperemesis gravidarum.
- Trial name
- NCT03950167
- Where
- Turkey (Türkiye)
- Volunteers
- 325 people, healthy volunteers welcome
- Sponsor
- Müge Keskin
To Assess the Impact of Bile Acids on Human Glukagon-like-peptide-1 Secretion
The Impact of Gall Bladder Emptying and Bile Acids on the Human GLP-1-secretion
The last couple of years it has been shown that bile acids not only acts as simple emulsifiers of fat, but constitutes a complex metabolic integrator which not only have an influence on fat digestion and lipid metabolism, but…
- Trial name
- NCT01656057
- Testing
- Acetaminophen, Metformin, Colesevelam
- Where
- Denmark
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Filip Krag Knop
Gall Bladder Disease
Operating Room Outcomes After Resident Training on a Virtual Reality Simulator
The purpose of this study is to compare outcomes of patients undergoing laparoscopic cholecystectomy before and after a laparoscopic training curriculum was implemented.
- Trial name
- NCT00459472
- Testing
- laparoscopic training curriculum
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Columbia University
Primary Sclerosing Cholangitis, Primary Biliary Cirrhosis
Repeatability and Reproducibility of Quantitative MRCP
This study aims to determine the repeatability and reproducibility of Quantitative Magnetic Resonance Cholangiopancreatography (MRCP).
- Conditions
- Primary Sclerosing Cholangitis, Primary Biliary Cirrhosis, Gallstones, Liver Diseases
- Trial name
- NCT03809559
- Testing
- MRCP+
- Where
- 2 sites in United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Perspectum
Gallstones
Contrastive Study for Minimally Invasive Cholecystolithotomy With Gallbladder Reservation and Laparoscopic Cholecystectomy
To explore the therapeutic effects for treatment of cholecystolithiasis by minimally invasive cholecystolithotomy with gallbladder reservation and laparoscopic cholecystectomy.
- Trial name
- NCT01822262
- Testing
- minimally invasive cholecystolithotomy with gallbladder reservation, laparoscopic cholecystectomy
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Chengyi Sun
Gall Stones (& [Calculus - Gall Bladder]), Surgery
Major Surgery as a Risk of Gall Stone Disease?
Gall stone disease is one of the most common diseases occurring in the world as well as in our country, Nepal. This disease is problematic to a lot of patients and poses a huge economic burden to the country.
- Trial name
- NCT04675190
- Testing
- Major abdominal Surgery
- Where
- 3 sites in Nepal
- Volunteers
- 755 people, healthy volunteers welcome
- Sponsor
- Nepal Medical College and Teaching Hospital
Drainage, Laparoscopic Cholecystectomy
The Efficacy and Safety of Using Prophylactic Abdominal Drainage After Cholecystectomy
Investigators want to assess the safety and efficacy of using abdominal drainage with not using any drainage, by estimating different outcomes after laparoscopic cholecystectomy for different reasons.
- Conditions
- Drainage, Laparoscopic Cholecystectomy, Acute Cholecystitis
- Trial name
- NCT05267860
- Testing
- Prophylactic Drain
- Where
- Syria
- Volunteers
- 232 people, healthy volunteers welcome
- Sponsor
- University of Aleppo
Dietary Habits
Dietary Factors and Risk of Gallbladder Carcinoma in China
The purpose of this study is to see how people's diets, other aspects of their lifestyles affect their chances of getting gallbladder carcinoma in China.
- Trial name
- DRGBC001 (NCT03546296)
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Yingbin Liu, MD, PhD, FACS
Gallbladder Diseases
A Novel Technique For Gall Bladder Fundus Retraction In Single Incision Laparoscopic Cholecystectomy
The investigators describe a novel technique for GB fundus retraction.
- Trial name
- NCT01413633
- Testing
- cholecystectomy
- Where
- Egypt
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Coronary Artery Disease, Congestive Heart Failure
Prognostic Indicators as Provided by the EPIC ClearView
The objective of this study is to determine whether the finger tip images captured by the EPIC ClearView device, when analyzed via the ClearView software, produce a Response Scale that characterizes trends consistent with known…
- Conditions
- Coronary Artery Disease, Congestive Heart Failure, Valvular Heart Disease, Atrial Fibrillation
- Trial name
- GBMC (NCT01476995)
- Where
- United States
- Volunteers
- 353 people, healthy volunteers welcome
- Sponsor
- Epic Research & Diagnostics, Inc.
Chronic Pancreatitis, Inflammatory Bowel Diseases
Genomic Resources for Enhancing Available Therapies (GREAT1.0) Study
This is a prospective, descriptive, observational research study designed to observe and document the clinical practice by domain experts, and how the knowledge of new findings that are published in the medical literature affect…
- Conditions
- Chronic Pancreatitis, Inflammatory Bowel Diseases, Hepatitis, NASH - Nonalcoholic Steatohepatitis
- Trial name
- GREAT1 (NCT04306939)
- Testing
- venipuncture, Questionnaires, Additional Sample Collections
- Where
- United States
- Volunteers
- 120,000 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Common Bile Duct Gallstones
Effect of Saline Irrigation to DEcrease Rate Of Residual Common Bile Duct Stones
In recent years, endoscopic sphincterotomy and stone extraction are standard procedures for the removal of bile duct stones. After procedures, there are some complications such as stone recurrence, papillary stenosis, cholangitis…
- Trial name
- SIDEROD (NCT01425177)
- Testing
- Normal Saline Irrigation
- Where
- South Korea
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Biliary Colic, Cholecystitis
Initial Experience With a New Laparoscopic Based Robotically Assisted Surgical System for Cholecystectomy
The Senhance™ surgical robotic system, previously known as Telelap Alf-X (TransEnterix, Morrisville, NC, USA) has recently become available in the UK.
- Trial name
- NCT03380572
- Testing
- Senhance Assisted Cholecystectomy, Laparoscopic Cholecystectomy
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Imperial College London