Clinical trials: Gambling, Pathologic
Pathological Gambling
An Open-Label Study of N-Acetyl Cysteine in Pathological Gambling
After completing all screening evaluations, subjects will receive unblinded N-Acetyl Cysteine 600 mg/day for 2 weeks. The dose will be raised to 1200 mg/day at visit 4 and to 1800 mg/day at visit 6 unless clinical improvement has…
- Trial name
- NCT00273702
- Testing
- N-Acetyl Cysteine
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Gambling Disorder
Effect of High-Intensity Transcranial Alternating Current Stimulation on Gambling Disorder: A Randomized Controlled Trial
The investigators assume that High-intensity transcranial Alternating Current Stimulation (HI-tACS) could improve gambling disorder patients' executive-control function by modulating abnormal neural activity, particularly…
- Trial name
- HITACSRCT-GD (NCT07228182)
- Testing
- HI-tACS
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
Gambling Disorder
Impact of a Self-Exclusion Procedure Optimized by an Extension of the Suspension of Commercial Solicitations
Considering that self-exclusion from gambling on a particular website is an intervention for and by individuals who have developed a gambling disorder, it is currently exclusively a behavioural intervention in the sense that it…
- Trial name
- PASS (NCT05413564)
- Testing
- optimized self-exclusion procedure by extending the suspension of commercial solicitations for a total of 9 months
- Where
- France
- Volunteers
- 2,554 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Gambling Disorder, Gambling Problem
Beliefs About Mental Health Treatment - Gambling Addiction Study in Colorado
Many people with mental health conditions do not seek treatment, and it is unclear what exactly prevents people from taking up treatment.
- Conditions
- Gambling Disorder, Gambling Problem, Mental Health Issue
- Trial name
- NCT06517849
- Testing
- Monetary Incentive for Take-Up of Cognitive Behavioral Therapy
- Volunteers
- 375 people, healthy volunteers welcome
- Sponsor
- Stanford University
Gambling
Drug Treatment for Pathologic Gambling Disorder
This study will establish the best dose of the drug naltrexone to treat patients with Pathological Gambling Disorder (PGD) and severe urge symptoms.
- Trial name
- NCT00053677
- Testing
- Naltrexone
- Where
- United States
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Gambling Disorder
Online Intervention to Promote Change and Help-Seeking in Young Adults With Gambling and Trading Problems
The goal of this study is to investigate if personalized online normative feedback (PONF) can increase intention to change and help-seeking behaviors in young adults with gambling or trading problems in Spain.
- Trial name
- NCT06681103
- Testing
- Personalized Normative Feedback
- Where
- Spain
- Volunteers
- 1,112 people, healthy volunteers welcome
- Sponsor
- Universidad Miguel Hernandez de Elche
Eye Tracking, Gambling Disorder
RCT for Gambling and Naltrexone, Using Use Eye-tracking Analysis to Predict Treatment Response
The primary objective of this study is to determine whether favorable response to naltrexone orally taken in treatment of GD can be predicted by patterns of visual scanning, assessed by eye-tracking technology before, at the…
- Conditions
- Eye Tracking, Gambling Disorder, Naltrexone
- Trial name
- NCT04738773
- Testing
- Naltrexone
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Gambling Disorder
BANCO Study: Behavioral Addictions and Related NeuroCOgnitive Aspects: A Monocentric, Prospective, Controlled, Open-label Study of a Sample of Patients With Gambling Disorder
The prevalence of people suffering from gambling disorder is relatively high, and the impact on this disorder the individual and those around him is considerable.
- Trial name
- BANCO (NCT03202290)
- Testing
- Cognitive and clinical assessment
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Nantes University Hospital
Pathological Gambling, Gambling Disorder
Effects of Intranasal Naloxone on Gambling Urges and Craving in Gambling Disorder
Primary objective: *To determine whether treatment with naloxone hydrochloride nasal spray reduces gambling urge symptoms in patients with gambling disorder The secondary objectives of the study are: To determine the effects of…
- Conditions
- Pathological Gambling, Gambling Disorder, Opioid Antagonist, Naloxone
- Trial name
- NalGamb (NCT03430180)
- Testing
- Naloxone hydrochloride
- Where
- Finland
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Finnish Institute for Health and Welfare
Pathological Gambling
D1 and D2 Dopamine Receptors in Gambling and Amphetamine Reinforcement
To determine if: 1. pathological gambling is similar to psychostimulant addiction as reflected by parallel roles for D1 and D2 receptors in gambling and stimulant reinforcement. 2.
- Trial name
- HFDEX (NCT02203786)
- Testing
- Haloperidol, Fluphenazine, Dexedrine
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Centre for Addiction and Mental Health
Gambling Disorder
Contingency Management as an Adjunct Treatment for Rural and Remote Disordered Gamblers
The purpose of this project is to pilot contingency management as an adjunct treatment to counselling as usual using internet delivered video-conferencing applications for remote disordered gamblers.
- Trial name
- NCT02953899
- Testing
- Contingency Management, Cognitive Behavioural Therapy
- Where
- Canada
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University of Lethbridge
Pathological Gambling, Obsessive Compulsive Disorder
Functional Magnetic Resonance Imaging (fMRI) Studies in Pathological Gambling (PG) and Obsessive-Compulsive Disorder (OCD)
This study will explore the brain processes associated with inhibition and reward processing in pathological gamblers and people with obsessive compulsive disorder compared to healthy controls.
- Trial name
- NCT00211822
- Testing
- fMRI
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Pathological Gambling
Community Reinforcement Approach and Family Training (CRAFT) for Problem Gambling
Nova Scotia is experiencing a proliferation of gambling opportunities and their related gambling problems. The 2003 Nova Scotia Prevalence Study (2004) found that approximately 50,000 adult Nova Scotians are at some risk for…
- Trial name
- NCT01340274
- Testing
- CRAFT treatment, Treatment as Usual
- Where
- 3 sites in Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- Colchester East Hants Health Authority
Pathological Gambling
Impulsivity in Pathological Gambling
The purpose of the this study is to compare pathological gamblers versus non-pathological gamblers using tests that measure different components of impulsivity.
- Trial name
- NCT00580567
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Impulsive Behavior, Impulse Disorders
Clinical Response of Impulsivity After Brain Stimulation in Parkinson's Disease
The objective of this prospective observational cohort study is to answer the following clinically important questions: 1. In patients with a pre-operative history of ICBs, what is the likelihood of improvement or deterioration…
- Conditions
- Impulsive Behavior, Impulse Disorders, Gambling, Pathological, Eating, Binge
- Trial name
- CRIPS (NCT04811807)
- Testing
- Subthalamic Nucleaus Deep brain stimulation
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- King's College London
Gambling Addiction
Testing the Interplay of Gambling, Emotion and Reward
Background The nature and direction of dysfunctional reward processing in gambling disorder remains unclear. We aim to test a novel neurobiological model of gambling addiction, that takes into account inter-individual…
- Trial name
- TIGER (NCT06122298)
- Testing
- fMRI, Ecological Momentary Assessment
- Where
- France
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Hôpital le Vinatier
Pathological Gambler
Environmental Influence on Gambling Behavior
In France, the prevalence of problem gambling and risk has been estimated at 1.3%. This disorder, currently considered a behavioral addiction is characterized by a loss of control and an excessive focus on the game.
- Trial name
- NCT02549781
- Testing
- Go-Nogo test
- Where
- France
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Gambling, Opioid
Treatment of Gambling Disorder With Fast Acting Opiate Antagonist, Naloxone Nasal Spray
Non-controlled pilot study. Two groups: Group A: naloxone nasal spray max 8 mg/per day; Group B: naloxone max 16 mg/per day. Study duration 8 weeks. Brief intervention.
- Conditions
- Gambling, Opioid, Naloxone, Spray
- Trial name
- NALPILO (NCT03223896)
- Testing
- Naloxone hydrochloride 20mg/ml
- Where
- Finland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Finnish Institute for Health and Welfare
Pathological Gambling
Poker, Skills and Associated Problems
The PERHAPS project aims to fill two gaps in the scientific literature: on the one hand, studying the clinical and cognitive particularities of poker-related problems, and on the other hand, studying poker skill as a combination…
- Trial name
- PERHAPS (NCT02590211)
- Testing
- cognitive, emotional and clinical assessment
- Where
- France
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- Nantes University Hospital
Gambling Problem
Exploring a Lottery-promoted Gambling Disorder Screening Day Intervention
The study is a randomized trial of gambling screening plus feedback (intervention) or gambling information (control) conditions, with data collection at baseline (T1) and a 3-month follow-up (T2).
- Trial name
- NCT06235333
- Testing
- Gambling Disorder Screening Day screener, Gambling Disorder Screening Day information sheet
- Volunteers
- 4,500 people, healthy volunteers welcome
- Sponsor
- Cambridge Health Alliance