Clinical trials: Gas Gangrene
Necrotizing Soft Tissue Infection, Necrotizing Fasciitis
Modulation of Biomarkers in Patients With Flesh-eating Bacterial Infections After With Hyperbaric Oxygen Treatment
The purpose of this study is to investigate the effects of hyperic oxygen treatment on the immune response in patients with necrotizing soft tissue infections
- Conditions
- Necrotizing Soft Tissue Infection, Necrotizing Fasciitis, Gas Gangrene, Fournier Gangrene
- Trial name
- BIONEC-II (NCT02501382)
- Where
- Denmark
- Volunteers
- 65 people
- Sponsor
- Ole Hyldegaard
Acute Ischemic Stroke From Large Vessel Occlusion
SGLT2 Inhibitor Utilization Re-perfusion Therapy
Background: Reperfusion therapies, including intravenous rt-PA and mechanical thrombectomy, significantly improve outcomes in acute ischemic stroke.
- Trial name
- SUPER (NCT06858436)
- Testing
- Canagliflozin 100mg
- Volunteers
- 150 people
- Sponsor
- Taichung Veterans General Hospital
Necrotizing Soft Tissue Infection, Necrotizing Fasciitis
Biomarkers in Patients With Flesh-eating Bacterial Infections
The purpose of this study is to investigate the immune response in patients with necrotizing soft tissue infections (NSTI). The investigation will focus on inflammatory and vasoactive biomarkers as prognostic markers of severity…
- Conditions
- Necrotizing Soft Tissue Infection, Necrotizing Fasciitis, Gas Gangrene, Fournier Gangrene
- Trial name
- BIONEC (NCT02180906)
- Where
- Denmark
- Volunteers
- 169 people
- Sponsor
- Ole Hyldegaard
Necrotizing Soft Tissue Infection, Necrotizing Fasciitis
Immunoglobulin for Necrotizing Soft Tissue Infections: a Randomised Controlled Trial
The purpose of this study is to estimate the effect of intravenous polyspecific immunoglobulin G (IVIG) compared with placebo (saline) on the patient-reported outcome measure Physical Component Summary Score (PCS) of the SF-36 in…
- Conditions
- Necrotizing Soft Tissue Infection, Necrotizing Fasciitis, Gas Gangrene, Fournier Gangrene
- Trial name
- INSTINCT (NCT02111161)
- Testing
- IVIG (Privigen), Saline 0.9%
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- Anders Perner
Ischemic Stroke
Glyburide Advantage in Malignant Edema and Stroke Pilot
The primary objective of this study is to assess the feasibility of enrolling, evaluating, and treating with glyburide for injection severe anterior circulation ischemic stroke participants, whether or not treated with standard…
- Trial name
- GAMES-PILOT (NCT01268683)
- Testing
- Glyburide for Injection
- Where
- 4 sites in United States
- Volunteers
- 10 people
- Sponsor
- Remedy Pharmaceuticals, Inc.
Air or Gas Embolism, Carbon Monoxide Poisoning
Hyperbaric Oxygen Therapy Registry
The purpose of the Hyperbaric Oxygen Therapy Registry (HBOTR) is to provide real world patient outcome and side effect information from electronic health records submitted to a specialty specific hyperbaric registry as part of…
- Conditions
- Air or Gas Embolism, Carbon Monoxide Poisoning, Clostridial Myositis and Myonecrosis (Gas Gangrene), Crush Injury, Compartment Syndrome & Other Acute Traumatic Ischemias
- Trial name
- HBOTR (NCT02483650)
- Volunteers
- 5,000 people
- Sponsor
- U.S. Wound Registry
Ischemic Stroke, Malignant Edema
Glyburide Advantage in Malignant Edema and Stroke - Remedy Pharmaceuticals
This is a randomized, multi-center, prospective, double blind study. The primary objective is to assess the efficacy and safety of glyburide (RP-1127) compared to placebo in participants with a severe anterior circulation…
- Trial name
- GAMES-RP (NCT01794182)
- Testing
- Glyburide for Injection
- Where
- 17 sites in United States
- Volunteers
- 86 people
- Sponsor
- Remedy Pharmaceuticals, Inc.
Necrotizing Soft Tissue Infection, Necrotizing Fascitis
Prognosis and Treatment of Necrotizing Soft Tissue Infections: A Prospective Cohort Study
The investigators will analyze biomarkers related to the prognosis and treatment of necrotizing soft tissue infections (NSTI). The focus will be on whether certain endothelial and immune system biomarkers can function as markers…
- Conditions
- Necrotizing Soft Tissue Infection, Necrotizing Fascitis, Gas Gangrene, Fournier Gangrene
- Trial name
- ProTreat (NCT03147352)
- Testing
- Hyperbaric oxygen therapy
- Where
- Denmark
- Volunteers
- 260 people
- Sponsor
- Ole Hyldegaard