Clinical trials: Gastric Bypass
Type 2 Diabetes, Cardiovascular Disease
DSS: Diabetes Surgery Study - Intensive Medical Management of Type 2 Diabetes, With and Without Gastric Bypass Surgery
The present study is the first stage of a research program whose ultimate goal is to conduct a randomized clinical trial involving type 2 diabetics with BMI from 30.0 to 39.9 kg/m2.
- Trial name
- DSS (NCT00641251)
- Testing
- intensive medical management, RYGB & IMM
- Where
- 5 sites in United States, Taiwan
- Volunteers
- 120 people
- Sponsor
- Medtronic - MITG
Gastric Bypass, Morbid Obesity
Simplified Technique for Performing Laparoscopic Gastric Bypass
This study will include all eligible patients who have undergone or who will undergo a laparoscopic gastric bypass procedure at Madigan Army Medical Center using a specific surgical technique developed by the Principal…
- Trial name
- NCT06782256
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- Madigan Army Medical Center
Gastric Outlet Obstruction
EUS-guided Versus Laparoscopic Gastrojejunostomy for Malignant Gastric Outlet Obstruction
Gastric outlet obstruction (GOO) is a common complication of various types of malignancy arising from the pancreas, bile ducts, retroperitoneum and distal stomach.
- Trial name
- EATING (NCT05605327)
- Testing
- EUS-guided gastroenterostomy, Laparoscopic gastroenterostomy
- Volunteers
- 120 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Roux En Y Gastric Bypass
Safety and Efficacy Study of Duet TRS
The objectives of this clinical trial are the overall performance and safety of the ENDO GIA Staplers with ENDO GIA SULUs with Duet TRS TM.
- Trial name
- NCT00950872
- Testing
- Duet TRS
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Medtronic - MITG
Morbid Obesity
One Anastomosis Gastric Bypass for Severe Obesity in 6,722 Patients: Early Outcomes From the Assuta Surgery Registry
Background: One-anastomosis gastric bypass (OAGB) is an emerging type of bariatric metabolic surgery (BMS). Our study aimed to evaluate the short-term (≤30-day) postoperative safety of OAGB.
- Trial name
- NCT05481853
- Testing
- One Anastomosis Gastric Bypass
- Where
- Israel
- Volunteers
- 6,722 people
- Sponsor
- Holy Family Hospital, Nazareth, Israel
Obesity, Insulin Resistance
Ghrelin and Insulin Resistance
Ghrelin, a hormone produced in the stomach that stimulates hunger and food intake, declines immediately after weight loss surgery. Some studies suggest that ghrelin may worsen an individual's ability to respond to insulin.
- Conditions
- Obesity, Insulin Resistance, Normal Weight,Healthy Controls
- Trial name
- NCT00884494
- Testing
- Ghrelin infusion to assess effects on insulin sensitivity
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Obesity, Morbid, Diabetes Mellitus, Type 2
Different Limb Lengths in Gastric Bypass Surgery
Obesity and type 2 diabetes mellitus (T2DM) are reaching epidemic proportions in the developed world. In morbidly obese patients only surgical treatment (bariatric operations) leads to a sustained weight loss and relief of…
- Conditions
- Obesity, Morbid, Diabetes Mellitus, Type 2, Hypertension, Dyslipidemias
- Trial name
- SLIM (NCT04219787)
- Testing
- Long BPL LRYGB, Short BPL LRYGB
- Where
- Switzerland
- Volunteers
- 800 people
- Sponsor
- Clarunis - Universitäres Bauchzentrum Basel
Type 2 Diabetes Mellitus
Determinants of Diabetes Remission After Gastric Bypass Surgery
Longitudinal study of beta cell function up to 2 years after GBP surgery. Evaluation of the role of endogenous glucagon-like peptide-1 (GLP-1).
- Trial name
- NCT02287285
- Testing
- Exendin9
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Blandine Laferrere
Malignant Gastric Outlet Obstruction
Comparing Endoscopic Ultrasound vs Surgical Gastrojejunostomy for Management of GOO.
The goal of this interventional study is to learn about the outcomes between two options for the management of malignant gastric outlet obstruction.
- Trial name
- RESTORE (NCT06128018)
- Testing
- Surgical gastrojejunostomy (S-GJ), EUS-guided gastrojejunostomy (EUS-GJ)
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- AdventHealth
Postoperative Complications, Operative Time
Eliminating Learning Curve Related Morbidity in Fast Track Laparoscopic Roux-en-Y Gastric Bypass
Background: Laparoscopic Roux en Y gastric bypass (LRYGB) is associated with a significant learning curve. We report the results of a systematic training programme from a high volume bariatric center measuring the outcome by…
- Conditions
- Postoperative Complications, Operative Time, Surgical Volume
- Trial name
- NCT01257789
- Testing
- laparoscopic gastric bypass
- Where
- Denmark
- Volunteers
- 300 people
- Sponsor
- Private Hospital Moelholm
Obesity, Metabolic Syndrome
Prospective Cohort Study of the Effect of Bariatric/Metabolic Surgery on Morbid Obesity Patients With Metabolic Syndrome
The purpose of this study is to determine the change in kidney function and blood pressure after gastric bypass versus conventional medical therapy in morbid obesity.
- Trial name
- NCT02271568
- Testing
- Bariatric surgery, Intensive medical therapy
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Hanyang University
Type 2 Diabetes, Obesity
The Effect of Roux-en-Y Gastric Bypass on Insulin Sensitivity in Type 2 Diabetes
Gastric bypass surgery induces remission of diabetes within days after surgery, before significant weight loss. The aim of the study is to examine whether improved insulin sensitivity of muscle and liver contributes to the…
- Trial name
- NCT01202526
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Hvidovre University Hospital
Severe Obesity
Determinants of Fat Malabsorption After Roux-en-Y Gastric Bypass
The purpose of this study is to determine whether or not the length of the biliopancreatic limb of the Roux-en-Y anastamosis plays a critical role in the development of malabsorption after gastric bypass for treatment of severe…
- Trial name
- NCT01252511
- Testing
- RYGB for surgical treatment of severe obesity
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Baylor Research Institute
Small Intestine Length Measurement
Digital 3D Reconstruction Predicts Small Bowel Length
The prevalence of type 2 diabetes mellitus (T2DM) has been increasing annually worldwide, and the prevalence of diabetes has reached 11.6% in China.
- Trial name
- DTDRPSBL-BS (NCT05338567)
- Testing
- Small intestine length measurement method
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Daping Hospital and the Research Institute of Surgery of the Third Military Medical University
Bariatric Surgery
Lexion AP 50/30 Warmed Humidified Real Time CO2 Insufflation vs Airseal Recirculated CO2/Air Insufflation in Minimally Invasive Bariatric (Gastric Bypass) Surgery
The purpose of this study is to To determine the effect of warm and humidified (WH) carbon dioxide (CO2) on post-operative pain/analgesia requirement in patients undergoing laparoscopic bariatric surgery.
- Trial name
- NCT05838300
- Testing
- Warm humidified CO2, Dry CO2
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- The University of Texas Health Science Center, Houston
Contraception
Drospirenone Only Pills and Cervical Mucus Changes: A Pre- and Post-Bariatric Surgery Study
The purpose of this study is to study the effect of Drospirenone on cervical mucus change by modified Insler score, pre-bariatric surgery and post-bariatric surgery
- Trial name
- NCT06345586
- Testing
- Drospirenone
- Where
- Thailand
- Volunteers
- 16 people
- Sponsor
- Chulalongkorn University
Laparoscopic Roux-en-y Gastric Bypass
The BlackBox Study
This is a hypothesis generating pilot study to compare the impact of 2D versus 3D visualization on surgical performance, as measured by the OR BlackBox platform, during laparoscopic bariatric surgery.
- Trial name
- NCT03252470
- Testing
- Laparoscopic Roux-en-y Gastric Bypass Surgery
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Olympus Corporation of the Americas
Type 2 Diabetes
Study of Comparison the Treatment Effect Between Gastric Bypass and Exenatide in Type 2 Diabetes
Objectives: To investigate the treatment effect between Gastric Bypass and Exenatide in Type 2 Diabetes in our hospital, in order to investigate the possible mechanism of Gastric Bypass and Exenatide.
- Trial name
- NCT01435980
- Testing
- Gastric Bypass, Exenatide
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Wu Qinan
Effect of Revisional Surgery for Failed Gastric Banding
Revisional Versus Primary Roux-en-Y Gastric Bypass: a Case Matched Analysis
This study compared revisional malabsorptive laparoscopic very very long limb gastric bypass (VVLL RYGB) with primary VVLL RYGB and tested the hypothesis that one staged revisional laparoscopic VVLL RYGB is a safe and effective…
- Trial name
- NCT01771744
- Volunteers
- 96 people
- Sponsor
- University Hospital, Basel, Switzerland
Morbid Obesity
Semaglutide Given Before and After Conversion of Sleeve Gastrectomy to Roux-en-Y Gastric Bypass for Recurrent Weight Gain
Recurrent weight gain affects 15% to 40% of patients after metabolic and bariatric surgery (MBS). SG is the most performed operation worldwide, and long-term regain after SG is well documented.
- Trial name
- NCT07859163
- Testing
- Semaglutide weekly injection
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- General Committee of Teaching Hospitals and Institutes, Egypt