Clinical trials: Gastric Bypass Surgery Pain Management
Laparoscopic Gastric Bypass Surgery, Ketamine
Perioperative Ketamine for Pain With Gastric Bypass
Opioid medications such as morphine, hydrocodone and oxycodone are standard for treating pain after surgery, however there are disadvantages.
- Trial name
- NCT03448068
- Testing
- Ketamine, Standard therapy
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Morbid Obesity, Postoperative Pain
Patients-Controlled Epidural Analgesia After Gastric Bypass for Morbid Obesity Using Morphine-Levobupivacaine Regimens
Adequate postoperative analgesia can facilitate recovery following gastric bypass surgery for morbid obesity. The efficacy and safety of intravenous patient - controlled analgesia has been studied, but up to date no data are…
- Conditions
- Morbid Obesity, Postoperative Pain, Postoperative Bowel Function, Postoperative Ambulation
- Trial name
- NCT01249872
- Testing
- GROUP A : 0 mg MORPHINE-0.1% LEVOBUPIVACAINE, GROUP B : 1 mg MORPHINE- 0.1% LEVOBUPIVACAINE, GROUP C : 2 mg MORPHINE-0.1% LEVOBUPIVACAINE
- Where
- Greece
- Volunteers
- 96 people
- Sponsor
- University of Patras
Pain, Postoperative Depression
Study on the Use of Low Dose Ketamine After Gastric Bypass and Gastrectomy
This is a randomized, double-blind, placebo-controlled, two-arm parallel, single-center study. One hundred subjects (50 in each arm) will be enrolled.
- Trial name
- NCT02452060
- Testing
- Ketamine
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- NYU Langone Health
Morbid Obesity
Efficacy of IV Acetaminophen in Acute Post-Operative Pain Control in Laparoscopic Roux-en-Y Gastric Bypass Surgery (LRYGBP) Patients
Laparoscopic Roux-en-Y gastric bypass (LRYGBP) is a common type of surgery in which length of stay and morbidity is intimately associated with post-operative nausea and vomiting (PONV) and recovery of bowel function.
- Trial name
- IV APAP (NCT01460667)
- Testing
- IV acetaminophen, IV normal saline
- Where
- United States
- Volunteers
- 85 people
- Sponsor
- McLaren Regional Medical Center
Morbid Obesity Requiring Bariatric Surgery, Postoperative Pain
Effect of Lidocaine-Dexmedetomidine on Pain, Inflammation, and Oxidative Stress After Bariatric Surgery.
The goal of this randomized clinical trial is to find out whether giving an intravenous lidocaine + dexmedetomidine combination (LIDEX) during laparoscopic bariatric surgery can lower post-operative pain, inflammation, and…
- Conditions
- Morbid Obesity Requiring Bariatric Surgery, Postoperative Pain, Postoperative Pain Management, Postoperative Analgesia
- Trial name
- NCT07073846
- Testing
- Intravenous Lidocaine infusion + Standard Anesthesia, Intravenous Dexmedetomidine infusion + Standard Anesthesia, Lidocaine + Dexmedetomidine Combination (LIDEX) + Standard Anesthesia
- Where
- 2 sites in Mexico
- Volunteers
- 104 people
- Sponsor
- Instituto Mexicano del Seguro Social
Pain, Postoperative, Pain, Chronic
Naldebain for Pain Control After Bariatric Surgery
Laparoscopic gastric sleeve and bypass surgeries the most common bariatric procedures for weight loss and improved management of metabolic syndromes.
- Conditions
- Pain, Postoperative, Pain, Chronic, Bariatric Surgery, Obesity
- Trial name
- NCT04651361
- Testing
- Dinalbuphine sebacate
- Where
- 2 sites in Taiwan
- Volunteers
- 60 people
- Sponsor
- E-DA Hospital
Post Operative Analgesia, Bariatric Surgery
Oral Acetaminophen for Post-Op Pain Management in Bariatric Surgery Patients
Adult patients with morbid obesity who have had Roux-en-Y gastric bypass (RYGB) or laparoscopic sleeve gastrectomy (LSG) surgery have impaired drug metabolism.
- Conditions
- Post Operative Analgesia, Bariatric Surgery, Bariatric Surgery (Gastric Bypass), Bariatric Surgery Patients
- Trial name
- NCT06658574
- Testing
- Acetaminophen
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Rutgers, The State University of New Jersey
Post-operative Pain
Preoperative Pain Control in Gastric Bypass Surgery Patients
Randomized clinical trial to evaluate whether a single pre-operative dose of Pregabalin will alleviate post-operative pain and decrease post-operative analgesic requirements in morbidly obese patients undergoing laparoscopic…
- Trial name
- NCT01801189
- Testing
- Pregabalin
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- Legacy Health System
Pain, Obesity
Pain Relieving Efficacy of TAP Block in Patients After Laparoscopic Gastric Bypass.
The purpose of this study is to determine whether injection of bupivacaine into the TAP is effective in the treatment of post operative pain after laparoscopic gastric bypass
- Conditions
- Pain, Obesity, Surgery, Neuromuscular Inhibition
- Trial name
- NCT01308554
- Testing
- Marcaine
- Where
- Denmark
- Volunteers
- 80 people
- Sponsor
- Funch-Jensen, Peter, M.D., D.M.Sc.
Gastric Bypass Surgery Pain Management
Transcranial Magnetic Stimulation Effects on Pain Perception
The purpose of this research study is to investigate the effects of Transcranial Magnetic Stimulation on pain perception. TMS is a non - invasive technique that uses electromagnetic pulses to temporarily stimulate specific brain…
- Trial name
- TMS (NCT01861574)
- Testing
- Real TMS 45 min, Real TMS 4 Hours
- Where
- United States
- Volunteers
- 108 people
- Sponsor
- Medical University of South Carolina
Pain, Postoperative, Postoperative Pain
Intraperitoneal Aerosolized Delivery of a Local Anesthetic for Post Operative Pain Management. A Double Blind, Randomised Controlled Clinical Trial.
The purpose of this study is to determine the effectiveness of aerosolized pain medication (.5% bupivicaine) delivered into the peritoneal cavity after laparoscopic gastric bypass surgery.
- Conditions
- Pain, Postoperative, Postoperative Pain, Abdominal Pain, Obesity
- Trial name
- NCT00286286
- Testing
- Intraperitoneal Aerosolization System, IntraMyst
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- Northgate Technologies
Pain, Postoperative
Intraoperative Lidocaine Infusion as a Sole Analgesic Versus Morphine in Laparoscopic Gastric Bypass Surgery
Postoperative opioid-centric pain management strategies in obese patients are accompanied by the possible development of; opioid-induced ventilatory impairment (OIVI) and hypoxemia.
- Trial name
- NCT05150756
- Testing
- Lidocaine Hydrochloride 2% Intravenous Solution [XYLOCAINE], morphine sulphate (10mg/ ml ampoule)
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Obese Patients, Bariatric Surgical Pain
Non-opioid Anesthesia Based on Thoracic Paravertebral Block During Laparoscopic Sleeve Gastrectomy
Regional anesthesia is a technique in which a local anesthetic is injected near a nerve or spinal cord to block sensation, motor stimulation, and pain.
- Conditions
- Obese Patients, Bariatric Surgical Pain, Bariatric Surgery (Sleeve Gastrectomy ), Non-Opioid Pain Management
- Trial name
- NCT07084753
- Testing
- Levobupivacaine, Dexamethasone contained in the solution for thoracic paravertebral block, Adrenaline
- Where
- Croatia
- Volunteers
- 36 people
- Sponsor
- IVO JURISIC
Pain, Postoperative Pain
REduced Pain After Bariatric Surgery - Gastric Bypass
This study aims to analyze the effect of laparoscopic guided transversus abdominis plane (LG-TAP) block compared to placebo for postoperative analgesia following laparoscopic gastric bypass.
- Conditions
- Pain, Postoperative Pain, Acute Pain, Analgesia
- Trial name
- REPABS-BPG (NCT06614257)
- Testing
- LG-TAP block with local anesthetic, Port site infiltration, LG-TAP block with saline solution
- Where
- Italy
- Volunteers
- 84 people
- Sponsor
- Fondazione Policlinico Universitario Campus Bio-Medico
Obese Patients
External Oblique Intercostal Block With or Without Intravenous Lidocaine Infusion for Analgesia in Patients Undergoing Gastric Bypass Surgery
Adding a perioperative lidocaine infusion (1.5 mg/kg loading + 1.5 mg/kg/h) to bilateral EOIB and low dose fentanyl loading reduces intraoperative fentanyl consumption (ANI guided rescue) compared to placebo, without increasing…
- Trial name
- NCT07809425
- Testing
- Investigatore hypothesize that adding a perioperative lidocaine infusion (1.5 mg/kg loading + 1.5 mg/kg/h) to bilateral EOIB and low dose fentanyl loading reduces intraoperative fentanyl consumption., Bilateral EOIB + fentanyl 1 μg/kg loading + normal saline loading (equivalent volume) + normal saline infusion (equivalent rate).
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Menoufia University