Clinical trials: Gastric Cancer in Situ
Esophageal Carcinoma, Gastric Cancer (Diagnosis)
Ph II Intraperitoneal Paclitaxel + System Therapy in GI Ca w/Peritoneal Carcinomatosis (STOPGAP-B)
This is a phase II open-label, basket clinical trial to assess the feasibility of systemic and Intraperitoneal chemotherapy in subjects with Gastrointestinal Malignancies with Peritoneal Carcinomatosis.
- Conditions
- Esophageal Carcinoma, Gastric Cancer (Diagnosis), Colorectal Adenocarcinoma, Appendiceal Adenocarcinoma
- Trial name
- NCT07795749
- Testing
- Paclitaxel Q2W, Paclitaxcel Q3W
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- University of California, Irvine
Gastric Cancer, Invasive Breast Cancer
CONFIRM: Magnetic Resonance Guided Radiation Therapy
This research is being done to determine the safety and feasibility of using a type of radiation guided by magnetic resonance imaging (MRI) and chemotherapy to treat patients with gastric and breast cancer.
- Conditions
- Gastric Cancer, Invasive Breast Cancer, in Situ Breast Cancer, Mantle Cell Lymphoma
- Trial name
- CONFIRM (NCT04368702)
- Testing
- Viewray MRIdian® Linac
- Where
- 2 sites in United States
- Volunteers
- 70 people
- Sponsor
- Brigham and Women's Hospital
Gastric Cancer, Gastric Adenocarcinoma
Stomach Cancer Exosome-based Detection
Gastric cancer continues to have a poor prognosis primarily due to the inability to detect it in its early stages. This study will develop and validate a blood assay to facilitate the non-invasive detection of gastric cancer.
- Conditions
- Gastric Cancer, Gastric Adenocarcinoma, Gastric Cancer Stage, Gastric Neoplasm
- Trial name
- DESTINEX (NCT06342427)
- Testing
- DESTINEX
- Where
- 3 sites in United States, Japan
- Volunteers
- 809 people, healthy volunteers welcome
- Sponsor
- City of Hope Medical Center
Low Grade Intraepithelial Neoplasia, High Grade Intraepithelial Neoplasia
Comparison of pCLE and EB in Gastric Lesion Diagnosis
This is a prospective multicenter comparative study, aiming to compare probe-based confocal laser endomicroscopy (pCLE) and endoscopic biopsies in the diagnosis of the whole specific gastric lesion especially for distinguishing…
- Conditions
- Low Grade Intraepithelial Neoplasia, High Grade Intraepithelial Neoplasia, Early Gastric Cancer, Gastric Intraepithelial Neoplasia
- Trial name
- NCT06389448
- Testing
- pCLE-gastr
- Where
- China
- Volunteers
- 366 people
- Sponsor
- Huazhong University of Science and Technology
Hepato-Biliary Carcinoma in Situ Nos, Pancreatic Cancer
Assessing the Accuracy of Seismofit® as an Estimate of VO2 Peak in Patients With Hepato-pancreato-biliary, Colorectal, and Gastro-oesophageal Cancer
Our study aims to assess the relationship between the Seismofit® derived VO2 peak estimate and CPET-measured VO2 peak in patients who are having CPET as part of their preoperative workup.
- Conditions
- Hepato-Biliary Carcinoma in Situ Nos, Pancreatic Cancer, Colorectal Cancer, Gastric Cancer
- Trial name
- VERVE (NCT05831488)
- Testing
- Non-Interventional
- Where
- United Kingdom
- Volunteers
- 35 people
- Sponsor
- Royal Marsden NHS Foundation Trust
Gastric Cancer in Situ, Pancreatic Cancers
Biweekly SOLAR, as First-line C/T in Pts With Gastric, Pancreatic and Biliary Cancers
The primary purpose of the study is to determine the maximal tolerated dose (MTD) of Oxaliplatin in this phase I study. The secondary objectives are to determine the response rate, progression free survival, overall survival, and…
- Conditions
- Gastric Cancer in Situ, Pancreatic Cancers, Biliary Cancers
- Trial name
- SOLAR (NCT03162510)
- Testing
- Oxaliplatin, Albumin-Bound Paclitaxel /nab-Paclitaxel, S-1
- Where
- Taiwan
- Volunteers
- 18 people
- Sponsor
- National Health Research Institutes, Taiwan
Gastric Dysplasia, Gastric Cancer in Situ
Endoscopic Closure of Gastric ESD Defect
This is a pilot study to investigate the usefulness of closure of mucosal defect after gastric endoscopic submucosal dissection (ESD) in patients that are at high risk of post-procedural haemorrhage.
- Trial name
- NCT04282707
- Testing
- Endoscopic closure of ESD defect, Gastric ESD without closure of ESD defect
- Where
- Hong Kong
- Volunteers
- 30 people
- Sponsor
- Chinese University of Hong Kong
Gastric Microbiota, Non-atrophic Gastritis
Difference of Gastric Microbiota in the Process of Correa's Model.
Helicobater pylori plays an important role in the development of gastric cancer. Eradication therapy can reducing the morbidity of gastric cancer, but can't totally prevent it especially when atrophy and more serious precancerous…
- Conditions
- Gastric Microbiota, Non-atrophic Gastritis, Atrophic Gastritis, Intestinal Metaplasia
- Trial name
- NCT02833363
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Shandong University