Clinical trials: Gastric Lesion
Gastric Precancerous Condition
Jianpi Huoxue Recipe in Treating Gastric Premalignant Lesion
This study had adopted the multi-center, randomized and controlled experiment design based on standardized mucosal biopsy and pathohistological operation, as well as therapeutic evaluation methodology.
- Trial name
- NCT03823248
- Testing
- MoLuoDan, Sanchi powder, Folic Acid Tablet
- Where
- China
- Volunteers
- 480 people
- Sponsor
- Xiyuan Hospital of China Academy of Chinese Medical Sciences
Gastric Intestinal Metaplasia, Gastric Cancer
Microbiome Analysis in Gastric Intestinal Metaplasia and in Gastric Cancer and Subtypes Correlation
The aim of the study will be to analyze the microbiome in the blood and stomach in patients with intestinal metaplasia (IM) and / or gastric cancer (GC).
- Conditions
- Gastric Intestinal Metaplasia, Gastric Cancer, Microbiome
- Trial name
- NCT04365946
- Testing
- Gastroscopy
- Where
- Greece
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ioannina
Stomach Neoplasms
Enhanced Magnifying Endoscopy for Diagnosis of Early Gastric Cancer
When performing screening endoscopy, small focal gastric lesions are frequently encountered. Novel techniques in endoscopy, such as magnifying endoscopy (ME) with narrow-band imaging (NBI) and chromoendoscopy with acetic…
- Trial name
- NCT01617876
- Where
- China
- Volunteers
- 282 people
- Sponsor
- Peking Union Medical College Hospital
Bladder Cancer, Cervical Cancer
Varenicline or Nicotine Patch and Nicotine Gum in Helping Smokers in a Methadone Treatment Program Stop Smoking
RATIONALE: Varenicline, the nicotine patch, and nicotine gum help people stop smoking. It is not yet known whether varenicline is more effective than the nicotine patch given together with nicotine gum in helping smokers quit…
- Conditions
- Bladder Cancer, Cervical Cancer, Esophageal Cancer, Gastric Cancer
- Trial name
- NCT00790569
- Testing
- nicotine, varenicline
- Where
- United States
- Volunteers
- 315 people
- Sponsor
- Butler Hospital
Peptic Ulcer
Feasibility of Translumenal Endoscopic Omental Patch Closure of Perforated Viscus
This study is being done to see if a new approach to repair perforated ulcers in the stomach (holes in the stomach) or the first part of the intestine is possible.
- Trial name
- NCT01080326
- Testing
- Endoscopic Translumenal Omental Patch
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Mayo Clinic
Acute Upper Gastrointestinal Non Variceal Hemorrhage
Endoscopic Diagnosis and Treatment of Acute Nonvariceal Upper Gastrointestinal Bleeding
Acute nonvariceal upper gastrointestinal bleeding (ANVUGIB) is a common critical disease in gastroenterology. Due to the development of modern medical technology, the incidence rate of ANVUGIB has been decreasing in recent years…
- Trial name
- NCT04895904
- Testing
- No intervention
- Volunteers
- 3,200 people
- Sponsor
- The First Affiliated Hospital of Nanchang University
Esophageal Varices
Study of Capsule Endoscopy to Determine the Accuracy for Detection of Esophageal Varices
Esophageal capsule endoscopy is sedation-less alternative to upper endoscopy for evaluating esophageal lesions and potentially other upper gastrointestinal lesions.
- Trial name
- NCT01079416
- Testing
- Capsule endoscopy, Esophagogastroduodenoscopy
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- University of California, Los Angeles
Gastric Dysplasia, Gastric Intestinal Metaplasia
Validation of an Artificial Intelligence System Based on Raman Spectroscopy for Diagnosis of Gastric Premalignant Lesions and Early Gastric Cancer
Early detection and treatment of gastric premalignant lesion and early gastric cancer (EGC) have been proposed to improve outcomes of gastric cancer.
- Conditions
- Gastric Dysplasia, Gastric Intestinal Metaplasia, Gastric Cancer
- Trial name
- NCT04869618
- Testing
- Raman spectroscopy based device (SPECTRA IMDx)
- Where
- Singapore
- Volunteers
- 100 people
- Sponsor
- Changi General Hospital
ESD Defect, Gastric Epithelial Lesion
Su2ura ESD Closure Pilot Study
This study is a single-center, prospective, single-arm, non-blinded first-in-human (FIH) early feasibility study intended to evaluate the short-term safety and technical feasibility of closure of gastric post-ESD defects using a…
- Trial name
- NCT07843719
- Testing
- Su2ura® GI system
- Volunteers
- 5 people
- Sponsor
- Chinese University of Hong Kong
Early Gastric Cancer
Screening for Early Gastric Cancer in Shaanxi Province
This study collect the relevant data of local residents over 20 years old in 11 regions of Shaanxi Province, The basic information of the subjects was collected by filling in the questionnaire, and serum helicobacter pylori…
- Trial name
- NCT05291728
- Where
- China
- Volunteers
- 12,500,000 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Xi'an Jiaotong University
Gastric Ulcer, Duodenal Ulcer, Acute Stress Gastritis, and Acute Gastric Mucosal Lesions
Lansoprazole Intravenous 30 mg Specified Drug-use Survey [Hemostatic Effect/Rebleeding Rate]
The purpose of this survey is to evaluate the safety (i.e., frequency of adverse events) and efficacy (i.e., hemostatic effect, rate of rebleeding after confirmation of hemostasis) of administration of lansoprazole intravenous 30…
- Trial name
- NCT02151786
- Testing
- Lansoprazole
- Volunteers
- 1,120 people
- Sponsor
- Takeda
Gastric Emptying
Feasibility of a Wireless Patch System (WPS) to Measure Gastrointestinal Motility and Gastric Emptying
The purpose of this study is to evaluate the utility of a new device - an external wireless patch system (WPS) - to measure gastric motility and to compare this external wearable device with the most commonly used test to measure…
- Trial name
- NCT05555407
- Testing
- Scintigraphic gastric emptying scan, Wireless patch system (WPS)
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Mayo Clinic
Low Grade Intraepithelial Neoplasia, High Grade Intraepithelial Neoplasia
Comparison of pCLE and EB in Gastric Lesion Diagnosis
This is a prospective multicenter comparative study, aiming to compare probe-based confocal laser endomicroscopy (pCLE) and endoscopic biopsies in the diagnosis of the whole specific gastric lesion especially for distinguishing…
- Conditions
- Low Grade Intraepithelial Neoplasia, High Grade Intraepithelial Neoplasia, Early Gastric Cancer, Gastric Intraepithelial Neoplasia
- Trial name
- NCT06389448
- Testing
- pCLE-gastr
- Where
- China
- Volunteers
- 366 people
- Sponsor
- Huazhong University of Science and Technology
Gastric Cancer, Atrophic Gastritis
Screening of Gastric Cancer Via Breath Volatile Organic Compounds by Hybrid Sensing Approach
The study is aimed to determine the potential of volatile marker testing for gastric cancer screening. The study will be addressing the role of confounding factors, including lifestyle factors, diet, smoking as well as addressing…
- Conditions
- Gastric Cancer, Atrophic Gastritis, Gastric Dysplasia, H.Pylori Infection
- Trial name
- VOGAS (NCT04022109)
- Testing
- Breath sampling for VOC detection, Surgery material collection for VOC headspace analysis, Upper endoscopy
- Where
- 5 sites in Brazil, Chile and 3 more
- Volunteers
- 5,000 people
- Sponsor
- University of Latvia
Gastrostomy Complications
LASER THERAPY IN GASTRIC STOMA INJURIES OF CHILDREN AND ADOLESCENTS
Compare the healing time of lesions in the mucosa of the gastric stoma of children and adolescents using laser therapy versus conventional treatment with protective barrier powder.
- Trial name
- NCT04863196
- Testing
- Laser therapy Treatment Group, Barrier Dust Treatment Group
- Where
- Brazil
- Volunteers
- 70 people
- Sponsor
- University of Sao Paulo General Hospital
Superficial Esophageal, Gastric or Colorectal Lesions
Validation of AI-ENDO System in Endoscopic Submucosal Dissection
This study is a pilot trial designed to evaluate the feasibility and safety of Al-ENDO assisted ESD in patients with gastrointestinal superficial lesions.
- Trial name
- NCT07392268
- Testing
- AI-ENDO system, Conventional ESD
- Where
- Hong Kong
- Volunteers
- 60 people
- Sponsor
- Chinese University of Hong Kong
Gastric Cancer, Gastric Intestinal Metaplasia
Surveillance of Patients With Precancerous Lesions of the Stomach
The project will aim to identify and determine subgroups of patients with different risks of progression to gastric cancer and to assess appropriate follow-up intervals.
- Conditions
- Gastric Cancer, Gastric Intestinal Metaplasia, Gastric Atrophy, Gastric Dysplasia
- Trial name
- NCT03250091
- Testing
- Upper endoscopy with biopsies, Plasma/serum sampling, Biopsies for gastric microbiota
- Where
- Latvia
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- University of Latvia
Capsule Endoscopy
MCE-new for Detection of Gastric Lesions
Clinical application of magnetically controlled capsule endoscopy : a prospective self-controlled trial
- Trial name
- NCT06020859
- Testing
- undergo NaviEC-2000Pro Gastro Scan mode, NaviEC-2000Pro Routine gastric examination, NaviEC-1000 Routine gastric examination
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital
Gastric Cancer
Identification of Biomarkers of Risk for Pre-neoplastic and Neoplastic Lesions for the Development of Gastric Cancer
Investigator propose the implementation of circulating biomarker monitoring, focusing on molecules related to the progression of gastric atrophy and/or associated with gastric cancer.
- Trial name
- DSCb score (NCT07374731)
- Where
- Italy
- Volunteers
- 192 people
- Sponsor
- Centro di Riferimento Oncologico - Aviano
Gastric Lesion, Gastritis
Capsule Gastric Endoscopy for Gastric Disease Screening in Simulated Home Scenarios
The goal of this clinical trial is to evaluate the diagnostic accuracy of the AI-integrated Capsule Gastroscopy (ACG) system in simulated home-use conditions for detecting upper gastrointestinal (UGI) abnormalities.
- Conditions
- Gastric Lesion, Gastritis, Upper Gastrointestinal Bleeding (UGIB), Gastric Dysplasia
- Trial name
- NCT06848400
- Testing
- AI-integrated Capsule Gastroscopy (ACG) examination, Electronic gastroduodenoscopy (EGD) examination
- Where
- 12 sites in China, Hong Kong and 1 more
- Volunteers
- 482 people, healthy volunteers welcome
- Sponsor
- Nanfang Hospital, Southern Medical University