Clinical trials: Gastro-Intestinal Disorder
Colon Cancer, Rectal Cancer
Assessing Effect of Withdrawal Time on Adenoma Detection Rate for Screening Colonoscopy
The investigators' null hypothesis is that a withdrawal time of 9 to 10 minutes is non-inferior to a withdrawal time of 12 minutes or greater.
- Conditions
- Colon Cancer, Rectal Cancer, Colorectal Cancer
- Trial name
- NCT05018325
- Testing
- Colonoscopy with 6 minute withdrawal, Colonoscopy 9 minute withdrawal, Colonoscopy 12 minute withdrawal
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Gastrointestinal Hemorrhage, Vascular Malformation
Efficacy Study of Thalidomide in Gastrointestinal Vascular Malformation Related Bleeding
Background: Repeated bleeding from gastrointestinal vascular malformations remains to be a major therapeutic challenge. Methods: The investigators performed a randomised, double-blind, placebo-controlled, single centre study to…
- Trial name
- NCT02754960
- Testing
- Thalidomide
- Where
- China
- Volunteers
- healthy volunteers welcome
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Enteropathogenic Escherichia Coli ., Colorectal Carcinoma
Enteropathogenic Escherichia Coli (EPEC): Does it Have a Role in Colorectal Tumourigenesis?
Despite the characterization of many aetiologic genetic changes. The specific causative factors in the development of sporadic colorectal cancer remain unclear.
- Trial name
- EPEC (NCT02373020)
- Testing
- colonoscopic biopsies
- Where
- Egypt
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Appetite Regulation
The Effect of Dietary Fibre and Plant Protein on Appetite and Metabolic Function
Acute effects on appetite and metabolic function have been observed for whole-grain rye cereal products. The aim of this study is to evaluate if the appetite suppressing effect of a whole-grain rye breakfast cereal may be further…
- Trial name
- NCT01965210
- Testing
- Rye + high dose inulin + low dose gluten, Rye + equal doses of inulin & gluten, Rye + low dose inulin + high dose gluten
- Where
- Sweden
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Swedish University of Agricultural Sciences
Obesity
Oro-gastro-intestinal Digestion of Emulsified Fat
Interaction of fat with the mouth, stomach and intestine will trigger physiological responses that will impact on the digestion, gut transit time and absorption of fat.
- Trial name
- NCT01478750
- Testing
- administration of fat (sunflower oil), emulsified, Insertion of nasoduodenal tube
- Where
- Netherlands
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Shigella Infection, Enterotoxigenic Escherichia Coli Infection
Shigella CVD 31000: Study of Responses With Shigella-ETEC Vaccine Strain CVD 1208S-122
The purpose of this study is to determine whether a live, oral, combined Shigella-ETEC vaccine candidate, known as strain CVD 1208S-122, is safe and immunogenic.
- Trial name
- NCT04634513
- Testing
- strain CVD 1208S-122
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Colorectal Cancer, Surgery
Human Blood Specimen Collection to Evaluate Immune Cell Function
Natural killer (NK) cells are leukocytes of the innate immune system and play a central role in the control of cancer metastases.
- Conditions
- Colorectal Cancer, Surgery, Perioperative Care
- Trial name
- NCT03422120
- Testing
- Natural Killer Cell Activity Assay
- Where
- Canada
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Ottawa Hospital Research Institute
Gastric Cancer, Gastric Adenocarcinoma
Near-infrared Imaging With Indocyanine Green for Detection of Peritoneal Metastases for Gastric Adenocarcinoma.
Peritoneal disease at initial presentation for patients with gastric adenocarcinoma (GA) is frequent, with 15-31% of patients presenting with peritoneal metastases (PM) at surgical exploration.
- Conditions
- Gastric Cancer, Gastric Adenocarcinoma, Peritoneal Carcinomatosis, Peritoneal Metastases
- Trial name
- NCT05687617
- Testing
- Indocyanine green
- Where
- 2 sites in Canada
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Laval University
Gastro-esophageal Reflux Disease
Validation of a Non-invasive In-vitro Diagnostic Test (Peptest) Against Other Diagnostic Methods for GERD
The primary objective of this clinical study is to determine whether Peptest (Human Pepsin lateral flow in vitro diagnostic medical device) is equivalent to other GERD diagnostic methods commonly applied in clinical practice by…
- Trial name
- PEPTESTCN (NCT02456779)
- Testing
- in vitro diagnostic test (Peptest), Questionnaire
- Where
- 9 sites in China
- Volunteers
- 1,032 people, healthy volunteers welcome
- Sponsor
- MAAB (Shanghai) Medical Device Limited
Malignant Neoplasm of Large Intestine
Effectiveness of Direct-to-Patient Outreach on Colorectal Cancer Screening Within a Low Income and Diverse Population
The purpose of this study is to determine if the direct mailing of fecal occult blood testing (FOBT) kits to patients who are due for colorectal cancer screening is an effective way to improve colorectal cancer screening rates…
- Trial name
- NCT01385579
- Testing
- Care manager outreach
- Where
- United States
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Acute Gastroenteritis
Yogurt Probiotic Bacteria on Relieving Young Children Acute Gastroenteritis
The goal of this clinical trial is to test the effect of mothers' application of yogurt probiotic bacteria on relieving their young children's acute gastroenteritis in children had two to five years old.
- Trial name
- NCT06090708
- Testing
- yogurt with probiotic bacteria
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Ulcerative Colitis, Pouchitis
Clotrimazole Enemas for Pouchitis in Children and Adults
Colectomy with creation of an ileal pouch (IPAA) is now the treatment of choice for patients with ulcerative colitis that is resistant to existing medical therapies.
- Conditions
- Ulcerative Colitis, Pouchitis, Ileitis, Inflammatory Bowel Disease
- Trial name
- CAPTURE (NCT00061282)
- Testing
- Clotrimazole
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Web
Gastric Cancers, Air Pollution
The Effect of Environmental Factors on Gastric Cancer Based on Macrogenome
The objectives of this study were to clarify how environmental factors such as air pollution affect the occurrence and development of gastric cancer; to identify patient-specific macrogenomic markers of gastric cancer; and to…
- Trial name
- NCT06854146
- Testing
- gastric cancer, healthy
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Dong Peng
Health Behavior, Colorectal Neoplasms
Health Behavior Change in High-Risk Colorectal Cancer Individuals
Background Colorectal cancer is a significant health concern. For individuals identified as being at high risk for developing this disease, adopting healthy lifestyle behaviors is a powerful way to lower that risk.
- Conditions
- Health Behavior, Colorectal Neoplasms, Primary Prevention/Methods
- Trial name
- NCT07262840
- Testing
- Multi-component Health Promotion Lifestyle Intervention, Standard Care
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- China Medical University, China
Irritable Bowel Syndrome
Is Microbiota Community Associated With Clinical Response to a Low FODMAP Diet in Patients With Irritable Bowel Syndrome
To determine the efficacy of a low FODMAP diet in IBS patients and whether gut microbiota community is associated with its efficacy.
- Trial name
- NCT02565550
- Testing
- low FODMAPs
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Shandong University
Inflammatory Bowel Diseases
Remote Physiologic Monitoring to Detect Inflammatory Bowel Disease (IBD) Flares: A Feasibility Study
Inflammatory bowel disease (IBD) has become a more prominent disease in the US population, with more than 3 million adults in the US affected.
- Trial name
- NCT04333810
- Testing
- Whoop strap 3.0
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
GERD
ANTI REFLUX MUCOSAL ABLATION THERAPHY (ARMA)
OBJECTIVES To study the safety and efficacy of Endoscopic Anti Reflux Mucosal Ablation (ARMA) procedure for the treatment of proton pump inhibitor (PPI) dependent gastro-esophageal reflux disease (GERD) DESIGN OF THE Prospective…
- Trial name
- ARMA (NCT04243668)
- Testing
- ANTI REFLUX MUCOSAL ABLATION THERAPHY (ARMA)
- Where
- India
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- Asian Institute of Gastroenterology, India
Breast Cancer, Cervical Cancer
Kukui Ahi Navigator Cancer Screening and Treatment Demonstration Project
This Cancer Prevention and Treatment Demonstration Project funded by the Centers of Medicare and Medicaid Services awarded six sites across the United States to develop Patient Navigator Programs to eliminate disparities in the…
- Conditions
- Breast Cancer, Cervical Cancer, Prostate Cancer, Colorectal Cancer
- Trial name
- NCT00379782
- Testing
- Navigation
- Where
- United States
- Volunteers
- 628 people, healthy volunteers welcome
- Sponsor
- Queen's Medical Center
Inflammatory Bowel Diseases
Prevention of Inflammatory Bowel Diseases in Persons at Risk The PIONIR (Preventing IBD Onset in Individuals at Risk) Trial
The goal of this study is to explore in a cross over randomized controlled trial, the ability of the Tasty\&Healthy dietary intervention (NCT04239248) to alter the parameters associated with future risk of developing Chron's…
- Trial name
- PIONIR (NCT05211518)
- Testing
- Tasty&Healthy, Habitual diet
- Where
- Israel
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Shaare Zedek Medical Center
Copd, Heart Failure
The Effect of Using Virtual Reality Glasses on Post-Care Pain and Comfort Level in Intensive Care Patients
The aim of this study is to determine the level of pain and comfort associated with the implementation of virtual reality prior to nursing care in patients undergoing treatment in the intensive care unit.
- Conditions
- Copd, Heart Failure, Intensive Care Unit Syndrome, Renal Failure
- Trial name
- NCT06923982
- Testing
- virtual reality, experimental group, control group
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Çankırı Karatekin University
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.