Clinical trials: Gastro-Intestinal Disorders
Laryngopharyngeal Reflux, Laryngopharyngitis Chronic
Method of Early Diagnosis of Laryngopharyngeal Reflux
The investigator will issue a Patient Information Consent for the participant in the study. 1.Patients will be asked to complete the Reflux Symptom Index questionnaire. Clinical survey, medical history. 2.
- Conditions
- Laryngopharyngeal Reflux, Laryngopharyngitis Chronic, Gastro Esophageal Reflux, Laryngitis
- Trial name
- LPR (NCT04771221)
- Testing
- pH metry, Filling out the questionnaire, Endoscopic laryngoscopy
- Where
- 2 sites in Kazakhstan
- Volunteers
- 385 people, healthy volunteers welcome
- Sponsor
- Kazakh Medical University of Continuing Education
Dysphagia
Specialize Dysphagia Training and Knowledge/Competency of Nurses
The aim of this research is to determine the effect of specialized dysphagia training on knowledge and competency of nurses.
- Trial name
- NCT05626361
- Testing
- Dysphagia training, Reading material
- Where
- Pakistan
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Copd, Heart Failure
The Effect of Using Virtual Reality Glasses on Post-Care Pain and Comfort Level in Intensive Care Patients
The aim of this study is to determine the level of pain and comfort associated with the implementation of virtual reality prior to nursing care in patients undergoing treatment in the intensive care unit.
- Conditions
- Copd, Heart Failure, Intensive Care Unit Syndrome, Renal Failure
- Trial name
- NCT06923982
- Testing
- virtual reality, experimental group, control group
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Çankırı Karatekin University
Ovarian Neoplasms, Breast Neoplasms
Establishment of a Tumor Bank for Blood Samples
Establishment of a tumor bank, consisting of blood samples of tumor patients and healthy people as controls. The blood samples will be collected systematically together with the corresponding clinical data.
- Conditions
- Ovarian Neoplasms, Breast Neoplasms, Colorectal Neoplasms, Neoplasms of the Female Genitalia
- Trial name
- NCT01763125
- Testing
- Blood collection
- Where
- 6 sites in Austria, Belgium and 2 more
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Colorectal Disorders, Colorectal Neoplasms
Comparison of the Left-Lateral Horizontal and Supine Positions for Colonoscopy Intervention: A Randomized Controlled Study
Objective: One of the most common technical difficulties during colonoscopy is passing through the fold of the sigmoid colon. Colonoscopy is commonly performed by endoscopists with the patient in the left lateral position.
- Conditions
- Colorectal Disorders, Colorectal Neoplasms, Colorectal Polyp, Colo-rectal Cancer
- Trial name
- NCT07517848
- Testing
- Colonoscopy after bowel cleansing
- Where
- Turkey (Türkiye)
- Volunteers
- 198 people, healthy volunteers welcome
- Sponsor
- Manisa Celal Bayar University
GERD
Endoscopic Band Ligation for Treating Reflux Disease
GERD is a chronic disease the require different treatment modalities; non have proven long term efficacy with concerns about their safety. The use of band ligation in endoscopy appears safe, repeatable with short learning curve.
- Trial name
- NCT06126055
- Testing
- Band Ligation
- Where
- Egypt
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- El Katib Hospital
Gastric Lesion, Gastritis
Capsule Gastric Endoscopy for Gastric Disease Screening in Simulated Home Scenarios
The goal of this clinical trial is to evaluate the diagnostic accuracy of the AI-integrated Capsule Gastroscopy (ACG) system in simulated home-use conditions for detecting upper gastrointestinal (UGI) abnormalities.
- Conditions
- Gastric Lesion, Gastritis, Upper Gastrointestinal Bleeding (UGIB), Gastric Dysplasia
- Trial name
- NCT06848400
- Testing
- AI-integrated Capsule Gastroscopy (ACG) examination, Electronic gastroduodenoscopy (EGD) examination
- Where
- 12 sites in China, Hong Kong and 1 more
- Volunteers
- 482 people, healthy volunteers welcome
- Sponsor
- Nanfang Hospital, Southern Medical University
Amyotrophic Lateral Sclerosis (ALS), Angina, Stable
Quest to Analyze One Thousand Humans Meditating
This study will be focused on assessing the molecular, physiological, and emotional correlates of an intensive meditation experience in the context of a retreat setting in a large 2000 plus-person cohort comprised of healthy and…
- Conditions
- Amyotrophic Lateral Sclerosis (ALS), Angina, Stable, Anxiety, Asthma
- Trial name
- QUANTUM (NCT06583395)
- Testing
- Advanced multi-component meditation practice
- Where
- United States
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Tobias Moeller-Bertram
Chronic Obstructive Pulmonary Disease, Bronchiectasis
The Prevalence of Gastro-oesophageal Reflux in Chronic Lung Disease
Gastric reflux into the oesophagus may further lung damage in respiratory disease. The proportion of adults with chronic lung disease and gastric reflux is unknown.
- Trial name
- NCT00697177
- Where
- Australia
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Bayside Health
Gastrointestinal Problem, Anxiety
Effects of a Microalgae Extract Dietary Supplement on Gut Health, Anxiety, and Immune Function
This study will be conducted to determine the effect of daily Tetrasol consumption in supporting gut health using assessments of gastrointestinal symptoms (GSRS) and bowel habits (BSS) as primary outcome measures.
- Conditions
- Gastrointestinal Problem, Anxiety, Stress, Gastrointestinal Symptoms
- Trial name
- Tetrasol (NCT06425094)
- Testing
- Microalgae Extract Capsules
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Colorado State University
Gastroesophageal Reflux
Natural History of Gastroesophageal Reflux (GER) in Children and Adolescents
The goal of this project is to determine the long-term health outcome of children diagnosed with gastroesophageal reflux (GER). We are inviting subjects that were previously followed in the Pediatric GI programs at Massachusetts…
- Trial name
- NCT00181805
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Drug Interaction, GERD (Gastroesophageal Reflux Disease)
A Study to Investigate the Effect of Linaprazan Glurate on the Pharmacokinetics of Amoxicillin
This is an open, single arm, single-center Phase I trial designed to evaluate the effect of seven days repeated oral doses of linaprazan glurate on the pharmacokinetics (PK) of repeated doses of amoxicillin in healthy male and…
- Conditions
- Drug Interaction, GERD (Gastroesophageal Reflux Disease), Safety, and Tolerability
- Trial name
- NCT07308041
- Testing
- Drug Drug Interaction
- Where
- Sweden
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Cinclus Pharma Holding AB
Gastroesophageal Reflux Disease
Can We Predict Who Has Gastroesophageal Reflux Disease (GERD)?
Gastroesophageal reflux disease (GERD) is currently defined as "a condition which develops when the reflux of stomach contents causes troublesome symptoms and/or complications".
- Trial name
- NCT01204931
- Where
- United States
- Volunteers
- 254 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Lactate, Healthy
Lactate in the Gut
Lactate is formed naturally in the body in example during physical activity. However, lactate is also formed during food fermentation where certain bacterial strains form lactate. Lactate can also be produced chemically.
- Conditions
- Lactate, Healthy, Hyperlactatemia
- Trial name
- NCT04299815
- Testing
- Oral Sodium Lactate, Intravenous sodium lactate
- Where
- Denmark
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
GERD - PPI Responders, GERD - PPI Non-responders
Acid Pocket: Position and Aspiration
Gastroesophageal reflux disease (GERD) is a very common condition affecting up to 30% of adults. To date, therapy consists of powerful acid suppression with proton pump inhibitors (PPI).
- Conditions
- GERD - PPI Responders, GERD - PPI Non-responders, Barrett Esophagus, Healthy Volunteers
- Trial name
- NCT02199002
- Testing
- multi-pH-impedance manometry catheter
- Where
- Belgium
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Degeneration Spine, Cervical Radiculopathy
Salt Water Gargling on Swallowing Following ACDF
The goal of this randomized control trial is to collect sufficient preliminary data on the efficacy of sodium chloride, hereafter referred to as "saltwater" or "saline" in reducing the difficulty of swallowing following…
- Conditions
- Degeneration Spine, Cervical Radiculopathy, Cervical Stenosis, Cervical Spondylosis
- Trial name
- NCT06475365
- Testing
- Sodium chloride gargle
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Gastroesophageal Reflux Disease
Factors Influencing the Human Gut Microbiome Profile in Multi-ethnic Groups of the Singapore Community (FAMES)
The objectives of this study are to examine the effects of ethnicity, gender, and proton pump inhibitor (PPI, omeprazole), on the human gut microbiome.
- Trial name
- FAMES (NCT02893709)
- Testing
- Omeprazole
- Where
- Singapore
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Changi General Hospital
Swallowing Disorder, Respiratory Insufficiency
The Impact of High-Flow Nasal Cannula on Swallow Function
Background: High-flow nasal cannula (HFNC) is a non-invasive heated and humidified oxygen delivery device that is capable of delivering high-flow rates.
- Trial name
- NCT03590457
- Testing
- Airvo 2; High-Flow nasal cannula system
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Gastrointestinal Disorders
Change in Permeability of the Small Intestine After Treatment With Gluten
The overall hypothesis of this research study is that gluten intake alters intestinal barrier function in patients with Irritable Bowel Syndrome (IBS) diarrhea who also exhibit non-celiac gluten sensitivity (NCGS).
- Trial name
- NCT02098057
- Testing
- Gluten Healthy
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Healthy Volunteers
A Study to Determine the Bioavailability of Vonoprazan Sprinkle Capsules on Pudding or on Applesauce Relative to a Vonoprazan Tablet in Healthy Participants
The primary objective of this study is to assess the bioavailability (BA) of a single oral dose of vonoprazan 20 mg sprinkle capsule, either sprinkled on pudding or on applesauce, relative to a vonoprazan 20 mg tablet in healthy…
- Trial name
- NCT05366738
- Testing
- Vonoprazan
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Phathom Pharmaceuticals, Inc.
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