Clinical trials: Gastro-Intestinal Disorders
Developmental Coordination Disorder, Lower Urinary Tract Symptoms
Impaired Toilet Training, LUTS and Bowel Dysfunction in Children With DCD
This cross-sectional case-control study aimed to determine whether there is a significant difference in the prevalence of impaired toilet training, LUTS, and functional bowel problems among children diagnosed with DCD and…
- Conditions
- Developmental Coordination Disorder, Lower Urinary Tract Symptoms, Bowel Dysfunction
- Trial name
- NCT06311110
- Testing
- Vancouver symptom score for dysfunctional elimination symptoms Questionnaire, Developmental Coordination Disorder Questionnaire, Questionnaire concerning impaired toilettraining and comorbities
- Where
- 2 sites in Belgium
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Healthy, Respiratory Disease
A Clinical Study to Map the HLA Genomic Region in the Greek Population
The aim of GENESIS clinical study is to map the HLA genomic region in the Greek population and evaluate possible correlations with selected underlying diseases.
- Conditions
- Healthy, Respiratory Disease, Chronic Renal Failure, Cardiovascular Diseases
- Trial name
- GENESIS (NCT06227468)
- Where
- 8 sites in Greece
- Volunteers
- 12,000 people, healthy volunteers welcome
- Sponsor
- Athens LifeTech Park
Irritable Bowel Syndrome, Colitis, Ulcerative
Advanced Metagenomic Analysis of Human Colonic Microbiota in Patients With Chronic GI Disorders
This clinical trial hypothesize that Gut Microbiota (bacteria, viruses, fungi)play a major role in the occurrence and progression of many chronic gastrointestinal diseases like Irritable Bowel Syndrome, Inflammatory Bowel…
- Conditions
- Irritable Bowel Syndrome, Colitis, Ulcerative, Crohn Disease, Colonic Neoplasms
- Trial name
- NCT01099111
- Where
- Saudi Arabia
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- King Fahad Medical City
Autism Spectrum Disorder, Gastrointestinal Symptoms
Combination Probiotic: BB-12 With LGG (Different Doses) in Treating Children With Autism Spectrum Disorder
This protocol is a blinded randomized controlled study of the effects of BB-12 with LGG at different doses in 70 healthy children with autism spectrum disorders at lower and higher doses over an 56-day period and a 28- day…
- Trial name
- NCT03514784
- Testing
- BB-12 with LGG (Higher Dose), BB-12 with LGG (Lower Dose)
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Postprandial Lipemia, Postprandial Glycemia
Exploring the Effects of Varying Fat:Carbohydrate Diet Permutations on Gastric Emptying and Metabolic Status Using Human Postprandial Model
The aim of this clinical trial is to investigate the effects of the meals moderated by fat and carbohydrate (CHO) quality along with varying macronutrient distribution (CHO: fat) on gut physiology and metabolic outcomes using the…
- Conditions
- Postprandial Lipemia, Postprandial Glycemia, Gastric Emptying
- Trial name
- NCT05977244
- Testing
- FIJA, F1JB, F2JA
- Where
- 3 sites in Malaysia
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Malaysia Palm Oil Board
Body Image, Urinary Incontinence
Pelvic Floor Dysfunction and Its Influence on Body Image and Sexual Function
The first objective to determinate the prevalence of pelvic floor dysfunction in pregnant women and in the first year postpartum.
- Conditions
- Body Image, Urinary Incontinence, Anal Incontinence, Anorectal Disorder
- Trial name
- PFD-BI (NCT03591393)
- Testing
- questionnaire
- Where
- Belgium
- Volunteers
- 328 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Stress, Irritable Bowel Syndrome
Evaluating and Treating Potential Research Participants With Digestive Disorders
Background: Some research studies focus on digestive disorders, such as nutritional, gastrointestinal, and liver disorders. Researchers want to examine and treat people with digestive disorders in order to learn more about these…
- Conditions
- Stress, Irritable Bowel Syndrome, Obesity, Abdominal Pain
- Trial name
- NCT01736280
- Testing
- Standard of Care
- Where
- United States
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- National Institute of Nursing Research (NINR)
Helicobacter Pylori
Feasibility Study of Phototherapy System to Treat H Pylori
This purpose of this study is to determine whether phototherapy can be used to safely and effectively treat H pylori.
- Trial name
- NCT00306280
- Testing
- Phototherapy
- Where
- 3 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- LumeRx
Alzheimer Disease, Caregiver Burden
Voice and Swallowing Disorders in Adults With and Without Alzheimer's Disease
This research study is investigating whether people with Alzheimer's disease experience more changes to voice and swallowing than their healthy age-matched peers.
- Conditions
- Alzheimer Disease, Caregiver Burden, Healthy Aging, Dysphonia
- Trial name
- NCT06328374
- Volunteers
- healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Barrett Esophagus, Esophageal Neoplasm
Novel Biomarkers in the Neoplastic Progression of Barrett's Esophagus
The purpose of this study is to determine if there are any early changes in DNA markers of blood and esophageal tissue in people with gastric reflux, Barrett's esophagus or esophageal cancer that can warn of a progression to…
- Conditions
- Barrett Esophagus, Esophageal Neoplasm, Gastroesophageal Reflux
- Trial name
- BE (NCT00431756)
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Cough, GERD
The Utility of Nexium in Chronic Cough and Reflux Disease
The purpose of this research study is to investigate different doses of proton pump inhibitors in reducing cough symptoms felt to be associated with Gastroesophageal reflux disease (GERD).
- Trial name
- NCT00287339
- Testing
- Esomeprazole
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Overactive Bladder, Urinary Incontinence
Percutaneous Nerve Evaluation With Fluoroscopy Versus Without
The investigators propose a randomized control trial comparing the rate of implantation of the InterStim device following Percutaneous Nerve Evaluation (PNE) performed with or without fluoroscopic guidance.
- Conditions
- Overactive Bladder, Urinary Incontinence, Fecal Incontinence
- Trial name
- NCT02677753
- Testing
- Fluoroscopy
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Louisville
Acne Vulgaris, Allergic Rhinitis
MedlinePlus Health Prescriptions: Developing a Pragmatic Approach for Clinic Use
The specific aim of this proposed pilot study is to compare two standardized processes (paper and electronic) to deliver a customized MedlinePlus health information prescription.
- Conditions
- Acne Vulgaris, Allergic Rhinitis, Anxiety, Asthma
- Trial name
- NCT01050465
- Testing
- health information prescription
- Volunteers
- 907 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Ovarian Neoplasms, Breast Neoplasms
Establishment of a Tumor Bank for Tissue Samples
Establishment of a tumor bank, consisting of tissue samples of tumor patients (benign and malign tumors) and healthy people as controls.
- Conditions
- Ovarian Neoplasms, Breast Neoplasms, Colorectal Neoplasms, Neoplasms of the Female Genitalia
- Trial name
- NCT01789229
- Testing
- Tumor tissue collection, Sampling of ascites and pleural effusion, Collecting urine samples
- Where
- 3 sites in Austria, Belgium and 1 more
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Dysphagia, Oropharyngeal, Swallowing Disorder
Validity and Reliability of the Turkish Version of the Sydney Swallow Questionnaire
Purpose of the study is the validity and reliability of the Turkish version of the Sydney Swallow Questionnaire (SSQ-T), so that it would be used as an assessment tool for Turkish dysphagia patients.
- Conditions
- Dysphagia, Oropharyngeal, Swallowing Disorder, Validation
- Trial name
- NCT04465903
- Testing
- Turkish Version of Sydney Swallow Questionnaire
- Where
- Turkey (Türkiye)
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Gut Microbiome, Gastrointestinal Microbiome
A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Disease
This study seeks to correlate microbiome sequencing data with information provided by patients and their medical records.
- Conditions
- Gut Microbiome, Gastrointestinal Microbiome, Autism, Autism Spectrum Disorder
- Trial name
- NCT04031469
- Testing
- There is no intervention in this study
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- ProgenaBiome
Breast Cancer Risk, Ovarian Cancer Risk
Population Based Germline Testing for Early Detection and Prevention of Cancer
PROTECT-C is a research study offering genetic testing to people to see whether they have a genetic change that increases their risk of breast, ovary, bowel, and/or womb cancer.
- Conditions
- Breast Cancer Risk, Ovarian Cancer Risk, Cancer Gene Mutation
- Trial name
- PROTECT-C (NCT07498829)
- Testing
- Genetic testing for Cancer Susceptibility Genes (CSGs) (BRCA1, BRCA2, RAD51C, RAD51D, BRIP1, PALB2, MLH1, MSH2, MSH6) and personalised breast and ovarian cancer risk
- Where
- United Kingdom
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- Queen Mary University of London
Ulcerative Colitis (UC), Crohn's Diseases
Cardiovascular Risk in Patients With IBD
In this study the Research Hospital San Donato Policlinic ask the participation with the aim to evaluate the risk of cardiovascular complication (i.e. stroke, myocardial infarction) in patients with inflammatory bowel disease.
- Conditions
- Ulcerative Colitis (UC), Crohn's Diseases, Cardiovascular Risk
- Trial name
- DICOM-IBD (NCT07663201)
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- IRCCS Policlinico S. Donato
Polycystic Ovarian Syndrome (PCOS)
Time Restricted Feeding Model in Women With Polycystic Ovary Syndrome
This study aims to evaluate the effects of a 16:8 time-restricted feeding (TRF) model on anthropometric, metabolic, and hormonal parameters in women with polycystic ovary syndrome (PCOS).
- Trial name
- NCT06807775
- Testing
- Dietary Intervention (time-restricted feeding model (16:8)), Dietary Intervention (energy restricted dietary intervention)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Rumination Syndrome
Baclofen for Children With Rumination Syndrome
The goal of this clinical trial is to learn about baclofen in pediatric patients with rumination syndrome. The main question it aims to answer is whether baclofen is effective in treating children with rumination syndrome.
- Trial name
- NCT05975684
- Testing
- Baclofen
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Nationwide Children's Hospital
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