Clinical trials: Gastrointestinal Decompression
Pancreatic Fistula, Pancreaticoduodenectomy
Effect of Trans-Nasal Afferent Loop Decompression on Post-Pancreaticoduodenectomy Pancreatic Fistula
Postoperative pancreatic fistula (POPF) is a major complication and an important cause of mortality after pancreaticoduodenectomy (PD).
- Conditions
- Pancreatic Fistula, Pancreaticoduodenectomy, Complication of Surgical Procedure
- Trial name
- NCT04989868
- Testing
- Trans-Nasal Afferent Loop Decompression, Without Trans-Nasal Afferent Loop Decompression
- Where
- China
- Volunteers
- 299 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Cancer of Stomach
Role of Routine Nasogastric Decompression After Subtotal Gastrectomy
The aim of the study is to evaluate whether subtotal gastrectomy without post-operative nasogastric decompression is better in terms of early post-operative bowel function and chest complication.
- Trial name
- NCT00164918
- Testing
- nasogastric tube
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Chinese University of Hong Kong
Anal Fistula
Decompression and Drainage Seton for Treatment of High Horseshoe Anal Fistula
Patients with high horseshoe anal fistula will be randomized to one of two equal group: treatment group will have decompression and drainage seton and control group will undergo cutting seton.
- Trial name
- DADS (NCT05044182)
- Testing
- Decompression and drainage seton, Cutting seton
- Where
- China
- Volunteers
- 92 people
- Sponsor
- China-Japan Friendship Hospital
Ileus, Bowel Obstruction
Stoma Tube Decompression and Postoperative Ileus After Major Colorectal Surgery
Postoperative ileus is common after colorectal surgery, occurring in up to 20% of patients. Stomas are frequently created in conjunction with major colorectal surgery.
- Trial name
- NCT01911793
- Testing
- Stoma Tube
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Cedars-Sinai Medical Center
Acute Lower Gastrointestinal Dysfunction
Should Colon or Non-colon Originated Lesions be Distinguished?
This prospective study was designed to compare the difference of effects of conventional treatment, medicine intervention, endoscopic therapy, and surgery between colon originated and non-colon originated ALGID in critical…
- Trial name
- NCT02939508
- Testing
- Colon originated: Neostigmin, Colonoscopy decompression, Surgery, Non-colon originated: Neostigmin, Colonoscopy decompression
- Where
- China
- Volunteers
- 158 people
- Sponsor
- Chinese Medical Association
Dysphagia After Anterior Cervical Decompression and Fusion of the Spine, Dysphonia
Dysphagia and Dysphonia in Anterior Cervical Spinal Surgery
Introduction: The anterior cervical approach is used to treat a variety of spinal disorders; among these, the Smith-Robinson approach is the most commonly used, as it allows access to discs, bony structures, and anterior lesions…
- Conditions
- Dysphagia After Anterior Cervical Decompression and Fusion of the Spine, Dysphonia, Anterior Cervical Spinal Surgery
- Trial name
- NCT07713693
- Testing
- Fiberoptic Endoscopic Evaluation of Swallowing, 30-item questionnaire designed to assess the impact of speech dysfunction on the patient's daily life, EAT-10 questionnaire
- Where
- Mexico
- Volunteers
- 36 people
- Sponsor
- Instituto Nacional de Rehabilitacion
Obstructive Jaundice, Pancreatic Cancer
Comparison of Metal and Plastic Stents for Preoperative Biliary Decompression
Covered self expandable metal stents (CSEMS) are three times larger in diameter than 10 Fr plastic stents. When compared to plastic stents, randomized trials have shown longer patency and fewer stent-related complications for…
- Trial name
- NCT01191814
- Testing
- Metal stent, Plastic stent
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- AdventHealth
Cholelithiasis
The Effect of Preoxygenation on Gastric Decompression in Laparoscopic Cholecystectomies
Aim: Gastric insufflation caused by mask ventilation during laparoscopic surgeries may affect the surgical field, lead to regurgitation of gastric contents, and consequently cause aspiration pneumonia.
- Trial name
- NCT07274488
- Testing
- Preoxygenation, Mask Ventilation
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people
- Sponsor
- Ankara City Hospital Bilkent
Distal Bile Duct Obstruction
Covered vs Uncovered Metal Stents for Palliative Biliary Decompression in Inoperable Malignant Distal Bile Duct Obstruction
The purpose of this study is to compare the rate of long-term stent failure, defined as need for repeat biliary intervention following placement of C-SEMS vs U-SEMS for palliation of inoperable malignant distal bile duct…
- Trial name
- NCT01905384
- Testing
- Covered Self-expanding metal biliary stents (C-SEMS), Uncovered Self-expanding metal biliary stents (U-SEMS)
- Where
- 2 sites in United States
- Volunteers
- 6 people
- Sponsor
- Vanderbilt University Medical Center
Pancreatic Cancer
Biliary Drainage Preceding Possible Pancreaticoduodenectomy. Are Self-expandable Metallic Stents (SEMS) Superior to Plastic Stents?
This study looks in to the rate of biliary stent dysfunction for plastic and metallic stents in patients who need biliary drainage due to a tumor in pancreas before possible pancreaticoduodenectomy.
- Trial name
- NCT03350763
- Testing
- Tannenbaum 10 Fr biliary stent, Self-expandable metallic biliary stent
- Where
- Finland
- Sponsor
- Helsinki University Central Hospital
Gastric Cancer
Gastric Decompression After Sub-total Gastrectomy
The purpose of this study is to test the utility of the nasogastric tube, which is used to decompress and as "guardian" of gastro-jejunal anastomosis, in patients undergoing distal subtotal gastrectomy for gastric cancer with…
- Trial name
- NCT01073046
- Testing
- Naso-Gastric/Jejunal Tube
- Where
- Italy
- Volunteers
- 276 people
- Sponsor
- Catholic University, Italy
Esophageal and Gastric Varices, Liver Cirrhosis
Decompression Intervention of Variceal Rebleeding Trial (DIVERT)
The Decompression Intervention of Variceal Rebleeding Trial (DIVERT) is a multi-center prospective randomized clinical trial comparing the radiologic procedure of transjugular intrahepatic portal-systemic shunt (TIPS) with the…
- Trial name
- NCT00006161
- Testing
- Transjugular Intrahepatic Portosystemic Shunt (TIPS), Distal Splenorenal Shunt
- Where
- 5 sites in United States
- Volunteers
- 140 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Pancreatic Head Neoplasm, Delayed Gastric Emptying
Nasogastric Decompression Following Pancreaticoduodenectomy
Pancreaticoduodenectomy (PD) remains the gold-standard operation for peri-ampullary neoplasms. Traditionally, gastric decompression via nasogastric intubation has been employed postoperatively to prevent nausea, vomiting…
- Conditions
- Pancreatic Head Neoplasm, Delayed Gastric Emptying, Post Operative Ileus, Whipple Procedure
- Trial name
- whipple (NCT06413888)
- Testing
- pancreaticoduodenectomy
- Where
- United States
- Volunteers
- 230 people
- Sponsor
- Baylor College of Medicine
Chronic Pancreatitis
Metabolic Impact of Pancreatic Duct Decompression
This study is a pilot study evaluating the impact of clearing out the pancreatic duct in patients with chronic pancreatitis who have a blockage in their pancreatic duct.
- Trial name
- NCT07810309
- Testing
- Endoscopic pancreatic duct decompression
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Mayo Clinic
Recurrent Cholecystitis, Cholecystitis
One vs. Two Stents for Gallbladder Disease
This randomized trial will look at whether placing two cystic duct stents is more effective than one cystic duct stent in preventing recurrent gallbladder disease (cholecystitis, gallstone pancreatitis, or biliary colic) among…
- Conditions
- Recurrent Cholecystitis, Cholecystitis, Symptomatic Gallbladder Disease, Biliary Colic
- Trial name
- NCT07222527
- Testing
- ERCP with one stent placement, ERCP with two stent placement
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Mayo Clinic
Digestive System Surgical Procedure, Pancreaticoduodenectomy
Impact of the Absence of Nasogastric Decompression After Pancreaticoduodenectomy
The use of nasogastric (NG) decompression after pancreaticoduodenectomy (PD) is a current practice. NG tube is associated with a high rate of morbidity including pulmonary morbidity, delayed gastric emptying and finally an…
- Trial name
- IPOD (NCT02594956)
- Testing
- no nasogastric tube, nasogastric tube
- Where
- France
- Volunteers
- 125 people
- Sponsor
- Rennes University Hospital
Colorectal Cancer, Postoperative Complications
The Impact of Transanal Decompression Tube Placement After Colorectal Anastomosis: A Randomized Trial
There is currently no standardization in the use of the transanal decompressive tube during the postoperative after a colorectal surgery. The available evidence is based on studies with methodological differences.
- Conditions
- Colorectal Cancer, Postoperative Complications, Anastomotic Leak, Anastomotic Complication
- Trial name
- SONDES (NCT04890015)
- Testing
- Intraoperative transanal decompression tube placement
- Where
- Spain
- Volunteers
- 202 people
- Sponsor
- Institut d'Investigació Biomèdica de Girona Dr. Josep Trueta
Gastric Cancer
Quality of Life After Routine Nasogastric Decompression After Distal Gastrectomy for Gastric Cancer Patients
The aim of the study is to evaluate whether distal gastrectomy without post-operative nasogastric decompression tube is better in terms of quality of life.
- Trial name
- NCT00738478
- Testing
- nasogastric tube, without nasogastric tube
- Where
- Japan
- Volunteers
- 180 people
- Sponsor
- Wakayama Medical University
Stroke, Stomach Acidity
Gastrointestinal Decompression in Stroke
Acute severe ischemic stroke is a life-threatening subtype of stroke. Due to stress ulcer and gastric reflux in acute stage, patients with severe ischemic stroke are always complicated with stomach bleeding and pulmonary…
- Conditions
- Stroke, Stomach Acidity, Pulmonary Infection, Gastrointestinal Decompression
- Trial name
- EAGER-ASSIST (NCT06214091)
- Testing
- Gastrointestinal decompression, Control
- Volunteers
- 60 people
- Sponsor
- Tianjin Medical University General Hospital
Obstructive Jaundice, Pancreatic Cancer
Trial Comparing Metal Versus Plastic Stents for Preoperative Biliary Decompression
Compare the performance of full covered metal stents and plastic stents for preoperative biliary decompression
- Trial name
- NCT01675908
- Testing
- Stent Dysfunction, Complications
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- AdventHealth