Clinical trials: Gastrointestinal Disorders, Functional
Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
Gastric Pathophysiology in Diabetes
This is a comprehensive pathophysiological study assessing various gastric functions in patients with diabetes mellitus. The investigators aim to examine the stomach with various measurement devices to gain information about its…
- Conditions
- Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2, Functional Dyspepsia, Gastroparesis
- Trial name
- DiaFLIP (NCT06068114)
- Where
- 5 sites in Czechia, Slovakia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Institute for Clinical and Experimental Medicine
Diverticulitis and Irritable Bowel Syndrome
Incidence and Predictive Factor of Irritable Bowel Syndrome After Acute Diverticulitis in Korea
The pathogenesis of irritable bowel syndrome (IBS) is considered immune reaction of gastrointestinal tract. Therefore there is growing evidence that IBS could occur after gastroenteritis.
- Trial name
- NCT02003807
- Where
- South Korea
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Overweight, Diabetes
Functional Ingredients: Effect in Gastrointestinal System
The addition of fructans or unripe banana flour to frozen meals can change the hormonal parameters related to hunger and satiety, improve the bowel movements and increase in colonic bacteria population measured by microbiological…
- Conditions
- Overweight, Diabetes, Constipation
- Trial name
- NCT02467972
- Testing
- Ready-to-eat frozen soups added unripe banana flour, Ready-to-eat frozen soups added maltodextrin, Ready-to-eat frozen soups added inulin
- Where
- Brazil
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Irritable Bowel Syndrome, Functional Dyspepsia
The Multi-disciplinary Treatment of Functional Gut Disorders Study
Randomised controlled trial comparing standard outpatient clinic treatment with multi-disciplinary clinic treatment for functional gastrointestinal disorders.
- Conditions
- Irritable Bowel Syndrome, Functional Dyspepsia, Constipation - Functional, Faecal Incontinence
- Trial name
- MANTRA (NCT03078634)
- Testing
- Multi-disciplinary clinic model, Standard outpatient care
- Where
- Australia
- Volunteers
- 188 people, healthy volunteers welcome
- Sponsor
- St Vincent's Hospital Melbourne
Gastro Esophageal Reflux
Esophageal and Gastric Registry and Biorepository
The evaluation of the foregut, the esophagus and stomach, has come a long way over the past two decades, and continues to experience exciting discoveries in the clinical evaluation of foregut physiology.
- Trial name
- NCT05180253
- Testing
- Esophageal studies
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Louisville
Cystic Fibrosis
Assessment of Cognitive Function and Exercise Capacity in Cystic Fibrosis
No studies in the literature have investigated the simultaneous effects of cognitive function, exercise capacity and arterial stiffness in adult patients with CF.
- Trial name
- NCT06175182
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Nonalcoholic Steatohepatitis (NASH)
Study to Evaluate the Pharmacokinetics of Firsocostat or Fenofibrate in Adults With Normal and Impaired Hepatic Function
The primary objectives of this study are to evaluate the single-dose pharmacokinetics (PK) of firsocostat in adults with normal hepatic function, and mild, moderate, or severe hepatic impairment and to evaluate the single-dose PK…
- Trial name
- HI (NCT02891408)
- Testing
- Firsocostat, Fenofibrate
- Where
- 5 sites in United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Gilead Sciences
Irritable Bowel Syndrome, Cyclical Vomiting Syndrome
Multi Modal Imaging: An MRI Study to Investigate Differences in the Structure and the Function of the Brain at Rest.
The structural/RSN study involves Structural and Resting State Neuroimaging. The purpose of Structural Neuroimaging is to use MRI technology to identify cortical and white matter morphometric differences between patients with…
- Conditions
- Irritable Bowel Syndrome, Cyclical Vomiting Syndrome, Ulcerative Colitis, Vulvodynia
- Trial name
- MMI (NCT01517516)
- Where
- United States
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Irritable Bowel Syndrome (IBS)
Diet and Motility in IBS
The goal of this observational study is to identify factors that influence symptoms in children with irritable bowel syndrome (IBS), to find ways to make diet treatments work better and possibly create personalized plans to help…
- Trial name
- IBS (NCT07283341)
- Testing
- Wireless Patch System
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Digestive Disorders, Irritable Bowel Syndrome
AcuGraph and Digestive Symptoms
This research is designed to study the reliability of the results of an AcuGraph in college students and faculty members with reported digestive symptoms
- Conditions
- Digestive Disorders, Irritable Bowel Syndrome, Constipation, Diarrhea
- Trial name
- NCT00846794
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Logan College of Chiropractic
Irritable Colon
Study to Assess the Effect Of Alosetron On Mucosal Blood Flow
This study will look at colonic mucosal blood flow in subjects who have taken alosetron vs placebo and healthy volunteers vs diarrhea-predominant Irritable Bowel Syndrome (d-IBS) patients.
- Trial name
- NCT00370032
- Testing
- alosetron
- Where
- United Kingdom
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
RED S, Eating Disorders
Relative Energy Deficiency in Sports (REDs) in Swedish Athletes
Background: Relative Energy Deficiency in Sport (REDs) describes impairment of health and performance due to problematic (long-term/severe) low energy availability (LEA), with or without eating disorders.
- Trial name
- REDs-Sweden (NCT06371963)
- Where
- Sweden
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Linnaeus University
Dysphagia, Esophageal
Striated Esophageal Motor Function Modulation in Health and Disease
The investigators hypothesize that striated esophagus deglutitive motor function is modulated by pharyngeal phase swallowing biomechanics.
- Trial name
- NCT05708885
- Testing
- Concurrent manometry/impedance and fluoroscopy with and without laryngeal restriction, Concurrent manometry/impedance and fluoroscopy before and after six weeks of using swallow muscle exercising device
- Where
- United States
- Volunteers
- 557 people, healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin
Paralytic Ileus, Nausea
The Impact of Preoperative Bowel Exercise on Postoperative Bowel Functions in Gynecologic Malignancies
Gastrointestinal dysfunction is a common complication after abdominal gynecologic oncology surgery. There are numerous studies in the literature addressing the management of bowel function in the postoperative period.
- Conditions
- Paralytic Ileus, Nausea, Defecation Disorder
- Trial name
- IPBEPOBF (NCT06113718)
- Testing
- Abdominal Exercise (digital rectal stimulation, abdominal massage)
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Tepecik Training and Research Hospital
Cirrhosis, Hepatic Encephalopathy
Brain Imaging in Patients With Chronic Liver Disease and Functional Impairment.
Hepatic encephalopathy (HE) is a frequent complication of chronic liver disease (cirrhosis) and involves a wide spectrum of problems from mild impairment of reaction times in driving and operating machinery through to…
- Trial name
- NCT00305591
- Testing
- l-ornithine l-aspartate
- Where
- United Kingdom
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Inflammatory Bowel Diseases, Irritable Bowel Syndrome
Randomized Controlled Trial of Citizen-targeted Evidence-based Resources
The purpose of this study is to determine whether an online resource developed to aid health consumers in making health decisions and better support them to seek quality evidence before other evidence is effective in the context…
- Trial name
- NCT04693780
- Testing
- Structured guide, List
- Where
- Canada
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- McMaster University
Chronic Obstructive Pulmonary Disease, Bronchiectasis
The Prevalence of Gastro-oesophageal Reflux in Chronic Lung Disease
Gastric reflux into the oesophagus may further lung damage in respiratory disease. The proportion of adults with chronic lung disease and gastric reflux is unknown.
- Trial name
- NCT00697177
- Where
- Australia
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Bayside Health
Inflammatory Bowel Disease, Ulcerative Colitis
Assessment of Colonic Permeability by Confocal Laser Endomicroscopy
The purpose of this study is to evaluate the efficacy of confocal laser endomicroscopy in assessment of colonic permeability against conventional sugar absorption test.
- Conditions
- Inflammatory Bowel Disease, Ulcerative Colitis, Irritable Bowel Syndrome
- Trial name
- NCT00883077
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Shandong University
Constipation-predominant Irritable Bowel Syndrome
Cheno Effect on Transit in Health and IBS-C
The study hypothesis is that the naturally occurring bile acid, chenodeoxycholic acid, induces acceleration of colonic transit in health and in patients with constipation-predominant Irritable Bowel Syndrome (IBS-C).
- Trial name
- Chenotransit (NCT00912301)
- Testing
- Sodium chenodeoxycholate (NaCDC)
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Irritable Bowel Syndrome
The Effect of the Low FODMAP Diet and Dietary Oligofructose on Gastrointestinal Form, Function and Microbiota
Some carbohydrates, complex sugars, which are found in grains, fruit and vegetables, cannot be digested by humans. When eaten they pass through the small bowel to the large bowel, or colon.
- Trial name
- FOG (NCT02259465)
- Testing
- low FODMAP diet, Oligofructose, Maltodextrin
- Where
- United Kingdom
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Nottingham