Clinical trials: Gastrointestinal Tumor Surgery
Gastric Cancer
Extended Resection After Positive Intraoperative Pathology in Gastric Cancer Surgery
Of 737 consecutive patients undergoing (sub)total gastrectomy for gastric or GEJ adenocarcinoma, 679 cases with curative intent surgery between 05/1996 and 03/2019 were included.
- Trial name
- NCT05663450
- Volunteers
- 679 people
- Sponsor
- University Hospital of Cologne
Synovial Cell Cancer, Melanoma
Evaluation for NCI Surgery Branch Clinical Research Protocols
Background: The National Cancer Institute Surgery Branch (NCI-SB) has developed experimental therapies that involve taking white blood cells from patients' tumor or from their blood, growing them in the laboratory in large…
- Conditions
- Synovial Cell Cancer, Melanoma, Colorectal Cancer, Lung Cancer
- Trial name
- NCT00001823
- Where
- United States
- Volunteers
- 7,000 people
- Sponsor
- National Cancer Institute (NCI)
Pancreatic Cancer
Fatigue and Pancreas and Bile Duct Cancer Study
The purpose of this pilot study is to determine the effects of a walking program on fatigue, physical functioning and QOL in patients with pancreatic and periampullary cancers who have had surgery or are undergoing adjuvant…
- Trial name
- NCT00902759
- Testing
- Walking Program
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University
Pancreatic Cancer
Standardization of Surgery on the Pancreatic Cancer
This study was designed to test the hypothesis that more extensive nodal and soft-tissue clearance in patients with adenocarcinoma of the head of the pancreas would improve survival without an increase in morbidity and mortality.
- Trial name
- NCT00679913
- Testing
- Standard pancreatoduodenectomy, Extended pancreatoduodenectomy
- Where
- South Korea
- Volunteers
- 244 people
- Sponsor
- Seoul National University Hospital
Neuroendocrine Tumors, Surgery
Prophylactic Cholecystectomy is Not Mandatory in Patients Candidate to the Resection for Small Intestine Neuroendocrine Neoplasms: a Propensity Score-matched and Cost-minimization Analysis
To evaluate two competitive strategies in patients undergoing resection of Small-intestine Neuroendocrine neoplasms (Si-NEN): Prophylactic Cholecystectomy (PC) versus On-demand delayed cholecystectomy
- Conditions
- Neuroendocrine Tumors, Surgery, Gut Tumor
- Trial name
- NCT04780737
- Testing
- Cholecystectomy
- Volunteers
- 230 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Stomach Neoplasms, Gastric Cancer
Specialization in Gastric Cancer Surgery
Specialization is having competent and effective knowledge on a subject, and the tendency towards specialization is increasing due to the fact that it increases the success in the follow-up and treatment process of diseases.
- Trial name
- NCT05280665
- Testing
- Specialization
- Where
- Turkey (Türkiye)
- Volunteers
- 537 people
- Sponsor
- Karadeniz Technical University
Stomach Neoplasms
Randomized Controlled Trials Comparing Clinical Outcomes of 3D Versus 2D Laparoscopic Surgery for Gastric Cancer
The purpose of this study is to explore the feasibility, safety, and efficacy of 3D Laparoscopic Surgery for Gastric Cancer. The patients with gastric adenocarcinoma (cT1-4aN0-3M0) were studied.
- Trial name
- NCT02327481
- Testing
- 3D Laparoscopic Surgery, 2D Laparoscopic Surgery
- Volunteers
- 438 people
- Sponsor
- Fujian Medical University
Pancreatic Adenocarcinoma, Pancreatic Cancer
AdV-tk Therapy With Surgery and Chemoradiation for Pancreas Cancer (PaTK01)
The purpose of this Phase 1 study is to evaluate the safety and potential efficacy of Gene Mediated Cytotoxic Immunotherapy for pancreatic cancer.
- Trial name
- PaTK01 (NCT00638612)
- Testing
- AdV-tk, Valacyclovir
- Where
- 3 sites in United States
- Volunteers
- 27 people
- Sponsor
- Candel Therapeutics, Inc.
Anal Squamous Cell Carcinoma, HIV Infection
Surgery in Treating Patients With Early Stage Anal Canal or Perianal Cancer and HIV Infection
This phase II trial studies surgery in treating patients with anal canal or perianal cancer that is small and has not spread deeply into the tissues and human immunodeficiency virus (HIV) infection.
- Conditions
- Anal Squamous Cell Carcinoma, HIV Infection, Stage 0 Anal Canal Cancer, Stage I Anal Canal Cancer
- Trial name
- NCT02437851
- Testing
- Therapeutic Conventional Surgery
- Where
- 5 sites in United States
- Volunteers
- 16 people
- Sponsor
- AIDS Malignancy Consortium
Hepatocellular Carcinoma, Liver Cancer
Efficacy and Safety Study of Bevacizumab and Erlotinib to Treat Primary Liver Cancer That Cannot be Removed By Surgery
The primary objective will be to assess progression-free survival (PFS) measured at 16 weeks following initiation of therapy with the combination of Avastin and erlotinib in patients with unresectable hepatocellular carcinoma…
- Trial name
- NCT00242502
- Testing
- Bevacizumab (Avastin), Erlotinib
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- M.D. Anderson Cancer Center
Metastatic Colorectal Carcinoma, Metastatic Lung Small Cell Carcinoma
M6620 and Irinotecan Hydrochloride in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery
This phase I trial studies the side effects and best dose of M6620 and irinotecan hydrochloride in treating patients with solid tumors that have spread to other places in the body (metastatic) or cannot be removed by surgery…
- Conditions
- Metastatic Colorectal Carcinoma, Metastatic Lung Small Cell Carcinoma, Metastatic Malignant Solid Neoplasm, Metastatic Pancreatic Carcinoma
- Trial name
- NCT02595931
- Testing
- Berzosertib, Biopsy Specimen, Biospecimen Collection
- Where
- 23 sites in United States
- Volunteers
- 66 people
- Sponsor
- National Cancer Institute (NCI)
Colorectal (Colon or Rectal) Cancer
Collagenase Biobank Study
The purpose of this study is to look at how bacteria present within the stool at the time of surgery and postoperatively may contribute to the development of cancer recurrence after surgery.
- Trial name
- NCT07211230
- Where
- United States
- Volunteers
- 107 people
- Sponsor
- University of Chicago
Colorectal Cancer
Immunoscintigraphy Using Radiolabeled Monoclonal Antibody in Finding Tumor Cells in Patients With Colorectal Cancer
RATIONALE: Diagnostic procedures, such as immunoscintigraphy, using a radiolabeled monoclonal antibody may help find and diagnose colorectal cancer.
- Trial name
- NCT00647153
- Testing
- pharmacological study, single photon emission computed tomography, iodine I 123 anti-CEA recombinant diabody T84.66
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- City of Hope Medical Center
Acinar Cell Adenocarcinoma of the Pancreas, Duct Cell Adenocarcinoma of the Pancreas
Chemoradiation and Radiosurgery Boost in Treating Patients With Locally Advance Pancreatic Cancer That May or May Not be Removed by Surgery
This phase I trial studies the side effects and best dose of radiosurgery boost following chemoradiation in treating patients with locally advanced pancreatic cancer that may or may not be removed by surgery.
- Conditions
- Acinar Cell Adenocarcinoma of the Pancreas, Duct Cell Adenocarcinoma of the Pancreas, Stage IIB Pancreatic Cancer, Stage III Pancreatic Cancer
- Trial name
- NCT01739439
- Testing
- gemcitabine hydrochloride, hyperfractionated radiation therapy, intensity-modulated radiation therapy
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Fox Chase Cancer Center
Quality of Life, Oesophageal Cancer
Quality of Life After Oesophageal or Gastric Cancer Surgery
This study aim to assess quality of life of patients 0-5 years after oesophageal or gastric cancer surgery and to develop and test an information and support program aiming to enhance the patients quality of life (QOL) after…
- Conditions
- Quality of Life, Oesophageal Cancer, Gastric Cancer
- Trial name
- NCT01657175
- Testing
- Supportive care
- Where
- Sweden
- Volunteers
- 82 people
- Sponsor
- Region Skane
Congenital Choledochal Cyst, Pediatric Surgery
Open vs. Laparoscopic Surgery for Pediatric Choledochal Cyst
This is a retrospective cohort study designed to compare the outcomes of open surgery versus laparoscopic surgery in pediatric patients diagnosed with congenital choledochal cyst (CCC).
- Conditions
- Congenital Choledochal Cyst, Pediatric Surgery, Surgical Outcomes, Open Surgery
- Trial name
- NCT06716762
- Testing
- Open Surgery, Laparoscopic Surgery
- Where
- South Korea
- Volunteers
- 72 people
- Sponsor
- In-Jin Jang
Gastric Cancer, Peritoneal Carcinomatosis
Efficacy of HIPEC Combined With Systemic Chemotherapy and CRS on Peritoneal Metastases From Gastric Cancer
This project is a multi-center, prospective, randomized controlled clinical observation the safety and efficacy that stage IV limited peritoneal metastasis of gastric cancer patients accept hyperthermic intraperitoneal…
- Trial name
- NCT03179579
- Testing
- HIPEC with neoadjuvant chemotherapy, Systemic chemotherapy
- Where
- China
- Volunteers
- 88 people
- Sponsor
- Shu-Zhong Cui
Gastric Cancer
Effect of Laparoscopy-Assisted Distal Gastrectomy for Locally Advanced Gastric Cancer
The purpose of this study is to evaluate the effect and safety of laparoscopy-assisted D2 radical surgery for distal advanced gastric cancer.
- Trial name
- SWEET (NCT02464215)
- Testing
- open surgery, laparoscopic surgery
- Where
- China
- Volunteers
- 440 people
- Sponsor
- Peking University Cancer Hospital & Institute
Carcinoma of the Appendix, Primary Peritoneal Cavity Cancer
Surgery and Oxaliplatin or Mitomycin C in Treating Patients With Tumors of the Appendix
This randomized phase II trial is studying the side effects and how well giving oxaliplatin or mitomycin C directly into the abdomen after surgery works in treating patients with tumors of the appendix.
- Trial name
- NCT01580410
- Testing
- mitomycin C, oxaliplatin, therapeutic conventional surgery
- Where
- 3 sites in United States
- Volunteers
- 136 people
- Sponsor
- Wake Forest University Health Sciences
Pancreatic Cancer, Surgery
Examining Safety, Efficacy and Feasibility of Preoperative Propranolol in Patients With PDAC.
The IMPULS trial is a randomized, triple-blinded, placebo controlled, single center, pilot trial examining the efficacy and safety of preoperative propranolol in patients scheduled for pancreatic cancer surgery.
- Trial name
- IMPULS (NCT06145074)
- Testing
- Propranolol
- Where
- 2 sites in Denmark
- Volunteers
- 30 people
- Sponsor
- Zealand University Hospital
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