Clinical trials: Gastrointestinal Tumor Surgery
Peritoneal Surface Malignancies
The Intraoperative Physiologic Changes of Patients Under Hyperthermic Intraperitoneal Chemotherapy (HIPEC) Cytoreductive Surgery; Prospective Observational Study
The most popular surgical treatment of peritoneal cancer is the type known as hyperthermic intraperitoneal chemoperfusion (HIPEC), a type of cytoreductive surgery for which a significantly high survival rate has been demonstrated…
- Trial name
- NCT02325648
- Testing
- HIPEC cytoreductive surgery
- Where
- South Korea
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Pancreatic Neoplasms, Pancreaticoduodenectomy
Benchmarking Outcomes in Pancreatic Surgery - WhippleBenchmarks.Org
The WhippleBenchmark 2 Collaborative study aims at defining benchmark criteria for best achievable outcomes after pancreaticoduodenectomy with portal vein resection.
- Trial name
- NCT04053998
- Testing
- Pancreaticoduodenectomy with portal vein resection
- Where
- 2 sites in Spain, United Kingdom
- Volunteers
- 1,462 people
- Sponsor
- Royal Free Hospital NHS Foundation Trust
Cancer of Colon, Anesthesia
Anesthesia and Cancer Study: Colon Cancer
This study investigates the influence of type of anesthesia on survival and recurrence rate in patients receiving colon cancer surgery. The participants will be allocated to either the TIVA group and the inhalation group.
- Trial name
- NCT04259398
- Testing
- Propofol, Sevoflurane
- Where
- 2 sites in South Korea
- Volunteers
- 797 people
- Sponsor
- Seoul National University Hospital
Colorectal Cancer, Primary Peritoneal Cavity Cancer
Systemic Chemotherapy With or Without Intraperitoneal Chemohyperthermia in Treating Patients Undergoing Surgery for Peritoneal Carcinomatosis From Colorectal Cancer
RATIONALE: Drugs used in chemotherapy, such as leucovorin, fluorouracil, and oxaliplatin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.
- Trial name
- NCT00769405
- Testing
- fluorouracil, leucovorin calcium, oxaliplatin
- Where
- 20 sites in France
- Volunteers
- 264 people
- Sponsor
- UNICANCER
Colorectal Disorders, Surgery--Complications
Evaluation of the Introduction of a Colorectal Bundle in Left Sided Colorectal Resections
The complication rate in colorectal surgery is high and shows a large variance depending on the patient and the treating surgeon.
- Conditions
- Colorectal Disorders, Surgery--Complications, Colorectal Cancer, Anastomotic Leak
- Trial name
- NCT04550156
- Testing
- Colorectal Bundle
- Where
- 7 sites in Switzerland
- Volunteers
- 1,141 people
- Sponsor
- University Hospital, Basel, Switzerland
Liver Cancer
Feasibility of a Minimally Invasive Image-Guided Surgery System for Hepatic Procedures
This study was designed to confirm that the surgeon is able to perform accurate liver surface registration including standard liver features used as landmarks during a scheduled laparoscopic liver procedure.
- Trial name
- NCT01238653
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Pathfinder Therapeutics
Gastrointestinal Neoplasms
Clinical Trial on Acupuncture Therapy in Patients With Gastrointestinal Neoplasms Laparoscopic Surgery
Patients accepted laparoscopic radical operation for carcinoma of colon and upper middle section of the rectum will be as the research object. Cancer patients are diagnosed based on pathology or cell biology.
- Trial name
- NCT02871245
- Testing
- Laparoscopic Surgery, Acupuncture treatment
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Xiaonan Cui
Lung Cancer, Esophageal Cancer
Pilot Study of Allogeneic Tumor Cell Vaccine With Metronomic Oral Cyclophosphamide and Celecoxib in Patients Undergoing Resection of Lung and Esophageal Cancers, Thymic Neoplasms, and Malignant Pleural Mesotheliomas
Background: Certain types of lung, esophageal, or thymic cancers and mesotheliomas have specific antigens (protein molecules) on their surfaces.
- Conditions
- Lung Cancer, Esophageal Cancer, Malignant Pleural Mesothelioma, Sarcoma
- Trial name
- NCT01143545
- Testing
- Allogeneic Tumor Cell Vaccine (K562), Celecoxib, cyclophosphamide
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- National Cancer Institute (NCI)
Laparoscopic Hepatectomy, Hepatocellular Carcinoma
Surgical Specification and Efficacy Evaluation of Total Laparoscopic Left Liver Resection
Recent clinical experience showed that laparoscopic hepatectomy has advantages of minimally invasive compared to open liver resection, however, laparoscopic liver resection is still difficult and risky.
- Trial name
- NCT02131441
- Testing
- laparoscopic hepatectomy, open liver resection
- Where
- China
- Volunteers
- 2 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Pancreatic Cancer, Pancreas Cancer
Does Cefoxitin or Piperacillin-Tazobactam Prevent Postoperative Surgical Site Infections After Pancreatoduodenectomy?
The purpose of this study is to figure out which commonly used antibiotic, cefoxitin or piperacillin-tazobactam, is better at decreasing the rate of surgical site infections after pancreatoduodenectomy.
- Conditions
- Pancreatic Cancer, Pancreas Cancer, Pancreatic Diseases
- Trial name
- NCT03269994
- Testing
- Cefoxitin, Piperacillin-tazobactam
- Where
- 32 sites in United States, Canada
- Volunteers
- 967 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Adenocarcinoma of the Rectum, Stage II Rectal Cancer
Oxaliplatin, Fluorouracil, and External-Beam Radiation Therapy Followed by Surgery in Treating Patients With Locally Advanced Cancer of the Rectum
Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells.
- Conditions
- Adenocarcinoma of the Rectum, Stage II Rectal Cancer, Stage III Rectal Cancer
- Trial name
- NCT00006094
- Testing
- oxaliplatin, fluorouracil, external beam radiation therapy
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- National Cancer Institute (NCI)
Pancreatic Cancer
Combination Chemotherapy in Treating Patients With Stage III or Stage IV Pancreatic Cancer That Cannot Be Removed by Surgery
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells.
- Trial name
- NCT00004003
- Testing
- cisplatin, fluorouracil, gemcitabine hydrochloride
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Barbara Ann Karmanos Cancer Institute
Colorectal Cancer, Esophageal Cancer
Nutritional Status and Nutrient Supply in Hospitalised Surgical Patients
Prospective single arm, single center observational study to assess the nutritional status and the nutrient supply during hospitalization for elective gastrointestinal surgery.
- Conditions
- Colorectal Cancer, Esophageal Cancer, Gastric Cancer
- Trial name
- NCT03787537
- Where
- Germany
- Volunteers
- 128 people
- Sponsor
- Charite University, Berlin, Germany
Lung Neoplasms, Liver Neoplasms
A Comparison of Methods for Assisting Needle Angle Selection During Image-guided Tissue Biopsy
Background: Currently, standard procedures for biopsies that are guided by computed tomography (CT) imaging involve CT scans and a computer program to plan and illustrate where the physician will place the needle to obtain the…
- Conditions
- Lung Neoplasms, Liver Neoplasms, Kidney Neoplasms, Cancer
- Trial name
- NCT01218854
- Testing
- Needle angle measurement
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Rectal Cancer
Closure of Protective Ileostomy 2 vs. 12 Weeks After TME
The purpose of this study is to compare the feasibility, safety, and quality of life (QOL) in patients (pts) undergoing protective ileostomy closure after 2 weeks with a closure after 12 weeks.
- Trial name
- Closure2vs12 (NCT02609451)
- Testing
- Ileostomy closure
- Where
- Switzerland
- Volunteers
- 71 people
- Sponsor
- Kantonsspital Liestal
Lung Neoplasms, Esophageal Neoplasms
The Impact of Different Anticoagulant Therapy on Hemorrhage and Coagulation After Thoracic Surgery
The purpose of this study is to determine whether the use of different dose of LMWH compared with fondaparinux for thromboprophylaxis is efficacious and safety after thoracic surgery.
- Conditions
- Lung Neoplasms, Esophageal Neoplasms, Venous Thromboembolism
- Trial name
- NCT01267305
- Testing
- Fondaparinux, Nadroparin Calcium
- Where
- China
- Volunteers
- 362 people
- Sponsor
- Shanghai Zhongshan Hospital
Colorectal Cancer, Surgery
Trial of Chewing Gum to Reduce Post Operative Ileus in Elective Colorectal Surgery
It is unknown whether post operative chewing gum will reduce post operative ileus. This study is a randomised controlled trial that will determine whether chewing gum three times a day following surgery will reduce post operative…
- Trial name
- NCT02372500
- Testing
- Chewing gum
- Where
- United Kingdom
- Volunteers
- 130 people
- Sponsor
- Countess of Chester NHS Foundation Trust
Adenocarcinoma, Stomach Neoplasm
Radiotherapy + Chemoimmunotherapy Followed by Surgery in Patients With Limited Metastatic Gastric or GEJ Cancer
The goal of this clinical trial is to evaluate the efficacy and safety of radiotherapy combined with chemotherapy and anti-PD-1 immunotherapy followed by surgery for the primary and metastatic lesions in patients with limited…
- Conditions
- Adenocarcinoma, Stomach Neoplasm, Gastroesophageal-junction Cancer, Oligometastatic Disease
- Trial name
- Miracle-G (NCT06121700)
- Testing
- Radiotherapy targeted to the primary lesion, Radiotherapy targeted to the metastatic lesions, Anti-PD-1 monoclonal antibody
- Where
- China
- Volunteers
- 55 people
- Sponsor
- Fudan University
Gastrointestinal Carcinoid Tumor, Islet Cell Tumor
Combination Chemotherapy as First-Line Therapy in Treating Patients With Locally Advanced or Metastatic Neuroendocrine Tumors of the Duodenum or Pancreas That Cannot Be Removed By Surgery
RATIONALE: Drugs used in chemotherapy, such as fluorouracil, leucovorin, and irinotecan, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.
- Conditions
- Gastrointestinal Carcinoid Tumor, Islet Cell Tumor, Neoplastic Syndrome
- Trial name
- NCT00416767
- Testing
- fluorouracil, irinotecan hydrochloride, leucovorin calcium
- Volunteers
- 20 people
- Sponsor
- Federation Francophone de Cancerologie Digestive
Colorectal Neoplasms, Neoplasm Metastasis
Resection Versus Microwave Ablation for Resectable Colorectal Cancer Liver Metastases
This single-center, prospective, randomized clinical trial is designed to compare the clinical characteristics and outcomes of hepatic resection and microwave ablation (MWA) to determine the optimal operative intervention for the…
- Conditions
- Colorectal Neoplasms, Neoplasm Metastasis, Hepatic Neoplasms
- Trial name
- NCT02866344
- Testing
- Microwave ablation, Hepatic resection
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Wake Forest University Health Sciences
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.