Clinical trials: Gastroparesis
Gastroparesis
A Study to Evaluate Safety, Side Effects, Muscle Activity and Speed of Gastric Emptying of GSK962040
Motilin is a peptide whose action is controlled by motilin receptors located in the gut. Action of Motilin at motilin receptors increases the gastric emptying rate (rate of emptying of food and fluid from the stomach).
- Trial name
- NCT00562848
- Testing
- GSK962040
- Where
- Belgium
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Gastroparesis, Diabetes Complications
To Study the EGG Abnormalities in Healthy Subjects and in Patients With Idiopathic and Diabetic Gastroparesis.
Electrogastrogram (EGG) is a non-invasive method for recording myoelectric activities by placing electrodes on the abdomen surface.
- Conditions
- Gastroparesis, Diabetes Complications, Idiopathic Gastric Motility Disorder, Dyspepsia
- Trial name
- NCT05624034
- Testing
- Electrogastrography
- Where
- India
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Asian Institute of Gastroenterology, India
Gastroparesis, Dyspepsia
Longitudinal Evaluation of Gastric Emptying and Accommodation in Children With Dyspepsia
The purpose of this research is to further study the relationship between gastroparesis (GP) (a condition in which the stomach cannot empty itself of food in a normal fashion) and functional dyspepsia (FD) (frequent symptoms of…
- Trial name
- NCT05055336
- Testing
- Gastric emptying breath test, Stomach ultrasound
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Miami
Gastroparesis
Comparison of Outcomes for Single vs Double Pyloromyotomy for Gastroparesis Randomized Controlled Trial
Gastroparesis is a chronic disease of the stomach that causes delayed gastric emptying without stenosis. The clinical symptoms of gastroparesis include nausea, vomiting, early satiety, post-prandial fullness, bloating, belching…
- Trial name
- COMET-GP (NCT06173336)
- Testing
- gastric per-oral endoscopic myotomy (G-POEM)
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Arkansas
Gastroparesis
GSK962040 Drug-drug Interaction Study With Ketoconazole
This study will determine the effect of 400 mg ketoconazole on the pharmacokinetics of a single dose of GSK962040. The results from this study will help to estimate the maximum increase in exposure during concomitant use of…
- Trial name
- NCT01039974
- Testing
- GSK962040, Ketoconazole
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Diabetic Polyneuropathy, Diabetic Gastroparesis
Pilot Study to Evaluate Magnetic Marker Imaging on Diabetic Polyneuropathy and Gastroparesis
The purpose of this study is to determine whether Magnetic Marker Monitoring is an appropriate opportunity to diagnose and to quantify a suspicious gastroparesis in subjects with diabetic polyneuropathy.
- Conditions
- Diabetic Polyneuropathy, Diabetic Gastroparesis, Diabetes Mellitus
- Trial name
- NCT01607684
- Testing
- Magnetic Marker Imaging (MMI) with Magma 3D system
- Where
- Germany
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Martin-Luther-Universität Halle-Wittenberg
Gastroparesis
Effect of Vibrant Capsule on Gastric Emptying and Antropyloroduodenal Motility in Healthy Volunteers
The Vibrant capsule is a novel vibrating device for the treatment of gastrointestinal disorders. The effect of different vibrations on the motor functions of the gastrointestinal tract are unclear.
- Trial name
- NCT02736799
- Testing
- Vibrant Capsule (1 vibration), Vibrant Capsule (3 vibration), Vibrant Capsule (5 vibration)
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Vibrant Ltd.
Fasting, Delayed Gastric Emptying
Gastric Assessment of Pediatric Patients Undergoing Surgery
The goal of this pilot prospective cohort study is to examine the reproducibility of gastric volume and emptying as measured by gastric ultrasound and its correlation to a gold-standard test for gastric emptying in the…
- Conditions
- Fasting, Delayed Gastric Emptying, Aspiration Pneumonia, Respiratory Aspiration of Gastric Content
- Trial name
- NCT05674643
- Testing
- Gastric Ultrasound Baseline Scans, Acetaminophen Absorption Test (AAT), Gastric Ultrasound Serial Scans
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Gastroparesis
ABCA2 GIRMS Analytical Validation Clinical Performance Study
The purpose of this study is to collect human breath samples for use in a validation study intended to demonstrate equivalent clinical performance measures of new ABCA2 GIRMS (Automated Breath Carbon Analyzer-2 Gas Isotope Ratio…
- Trial name
- NCT04607304
- Testing
- ABCA2 GIRMS
- Where
- United States
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Cairn Diagnostics
Gastroparesis
Gastric Per-Oral Endoscopic Myotomy (G-POEM) for the Treatment of Gastroparesis
Gastric Per-Oral Endoscopic Myotomy (G-POEM) is a procedure for the Treatment of Gastroparesis.
- Trial name
- G-POEM (NCT04434781)
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Indiana University
Glucagon Like Peptide-1 (GLP-1, Delayed Gastric Emptying
GLP_1 RA Ultrasound Study
The purpose of the study is to determine whether patients taking GLP-1 RAs have increased residual (left behind), gastric (stomach), contents due to delayed gastric emptying when following standard preoperative fasting guidelines.
- Conditions
- Glucagon Like Peptide-1 (GLP-1, Delayed Gastric Emptying, Risk of Aspiration, Diabetes
- Trial name
- NCT06581120
- Testing
- Glucagon-Like Peptide-1 receptor agonists, Point of Care Gastric Ultrasound
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Diabetic Gastroparesis, Diabetic Gastropathy
Washed Microbiota Transplantation Alleviates Diabetic Gastrointestinal Motility Disorders: an Efficacy and Safety Study
The goal of this clinical trial is to learn about effectiveness and safety of washing microbiota transplantation in diabetic gastrointestinal motility disorders participant population.
- Conditions
- Diabetic Gastroparesis, Diabetic Gastropathy, Diabetic Gastroenteropathy, Diabetic Gastroparesis Associated With Type 2 Diabetes Mellitus
- Trial name
- NCT06340828
- Testing
- Washing Microbiota Transplantation
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- The Second Hospital of Nanjing Medical University
Delayed Gastric Emptying
Reference Values for Gastric Emptying
Healthy volunteers will ingest a 13C-octaoate containing test meal and 13C in expiratory air will be followed. Normal values will be calculated data of these tests.
- Trial name
- 13C (NCT02397577)
- Testing
- Solid test meal, liquid test meal on two separate occations
- Where
- Switzerland
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Diabetics Without Symptoms of Gastroparesis, Diabetic Gastroparesis
Biomagnetic Characterization of Gastric Dysrhythmias III
There is a tremendous clinical need for a noninvasive technique that can assess gastric electrical activity and would be repeatable without any exposure to radiation.
- Conditions
- Diabetics Without Symptoms of Gastroparesis, Diabetic Gastroparesis, Idiopathic Gastroparesis, Total or Partial Gastrectomy
- Trial name
- NCT03176927
- Testing
- magnetogastrogram
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Diabetes Mellitus, Gastroparesis
Drug Trial of Lixisenatide on Gastric Emptying and Blood Pressure Drops in Type 2 Diabetics and Healthy People
The purpose of this study is to determine the effects of the drug lixisenatide on blood sugar levels, stomach emptying, blood pressure and heart rate, release of gut hormones and blood flow in the gut after a glucose drink in…
- Trial name
- Lixi (NCT02308254)
- Testing
- Lixisenatide
- Where
- Australia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Royal Adelaide Hospital
Diabetes, Gastroparesis With Diabetes Mellitus
PET Imaging to Delineate Macrophage Activation in Diabetic Gastroparesis
Macrophage-driven immune dysregulation has been shown to be involved in pathophysiology of diabetic gastroparesis. Currently, there are no non-invasive ways to study macrophage activation in humans.
- Trial name
- NCT04762719
- Testing
- PET/CT Scan with 11C-ER176, Core biopsy of gastric muscle
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Gastroparesis, Diabetes Mellitus
Effects of Sitagliptin on Gastric Emptying in Healthy Subjects
The purpose of this study is to determine the effects of the drug, sitagliptin, on the rate at which the stomach empties, and the release of gut hormones and blood glucose concentrations, after a mashed potato meal in healthy…
- Trial name
- NCT00501657
- Testing
- Sitagliptin
- Where
- Australia
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Royal Adelaide Hospital
Gastroparesis
Magnetic Resonance Imaging of the Brain and Stomach in Healthy Volunteers and Gastroparesis
The study is to lay the groundwork for non invasive imaging of the GI tract and the brain gut interaction
- Trial name
- NCT04282317
- Testing
- MRI scan
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Indiana University
Gastroparesis
13C-Spirulina Nitrogen Content GEBT Study
The purpose of this study is to determine whether there is a difference in the human in vivo response to 13C-Spirulina meals manufactured using 13C-Spirulina containing different levels of protein (as measured by %nitrogen).
- Trial name
- NCT04635306
- Testing
- Approved GEBT test meal
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Cairn Diagnostics
Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
Gastric Pathophysiology in Diabetes
This is a comprehensive pathophysiological study assessing various gastric functions in patients with diabetes mellitus. The investigators aim to examine the stomach with various measurement devices to gain information about its…
- Conditions
- Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2, Functional Dyspepsia, Gastroparesis
- Trial name
- DiaFLIP (NCT06068114)
- Where
- 5 sites in Czechia, Slovakia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Institute for Clinical and Experimental Medicine