Clinical trials: Gastroscopy; Gastric Cancer
Esophagogastroduodenoscopy, Simethicone
Premedication With N-acetylcysteine and Simethicone to Improve Mucosal Visualization in Elective Upper Endoscopy
The goal of this randomized, double-blind, placebo-controlled clinical trial is to assess whether the combination of N-acetylcysteine and simethicone improves mucosal visibility during upper gastrointestinal endoscopy in adults…
- Conditions
- Esophagogastroduodenoscopy, Simethicone, N-Acetylcysteine, Premedication
- Trial name
- NACSIMET (NCT07245095)
- Testing
- Premedication with n-acetylcysteine, Premedication with simethicone
- Where
- 2 sites in Mexico
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Hospital General de Mexicali
Stomach Neoplasms
Premedication With Simethicone or Simethicone Plus N-acetylcysteine in Improving Visibility During Upper Endoscopy
The purpose of this study is to determine whether premedication with Simethicone or Simethicone plus N-acetylcysteine are effective improving visibility during Upper endoscopy compared with use of water or no preparation.
- Trial name
- PRUE (NCT01653171)
- Testing
- Simethicone, N-acetylcysteine 500 mg, N-acetylcysteine 1000 mg
- Where
- Chile
- Volunteers
- 230 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Stomach Neoplasms, Stomach Diseases
One-Click Autofocus Versus Segmented Focus in Gastric Endoscopy
Magnifying endoscopy provides high-resolution images that enhance the detection of early gastrointestinal lesions. However, conventional manual zoom techniques require frequent focal adjustments, which can be technically…
- Trial name
- NCT07664813
- Testing
- One-Click Autofocus, Segmented Focus
- Where
- China
- Volunteers
- 93 people
- Sponsor
- Shandong University
Gastric Diseases,, Gastric Ulcer,
Magnetic-controlled Capsule Endoscopy vs. Gastroscopy for Detection of Gastric Diseases
A new Magnetic-controlled Capsule Endoscopy (MCE) was developed by ANKON and got SFDA's approval in China in 2013. It has recently been evaluated to compare the diagnostic accuracy of MCE with that of standard gastroscopy for…
- Conditions
- Gastric Diseases,, Gastric Ulcer,, Gastric Polyps,, Early Gastric Cancer,
- Trial name
- MCE (NCT02219529)
- Testing
- MCE, Standard gastroscopy
- Where
- China
- Volunteers
- 350 people
- Sponsor
- Changhai Hospital
Helicobacter Pylori Infection, Atrophic Gastritis
Artificial Intelligence for Determination of Gastroscopy Surveillance Intervals
The purpose of this study is to develop and validate a clinical decision support system based on automated algorithms. This system can use natural language processing to extract data from patients' endoscopic reports and…
- Conditions
- Helicobacter Pylori Infection, Atrophic Gastritis, Intestinal Metaplasia, Low Grade Intraepithelial Neoplasia
- Trial name
- NCT05631015
- Testing
- AI recongnize disease and generate recommendations
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Xiuli Zuo
Gastroscopy Time, Early Gastric Cancer
Setting the Shortest Examination Time of Gastroscopy to Improve the Detection Rate of Upper Gastrointestinal Tumors
This multicenter, prospective, interventional study aims to include 2000 gastroscopic procedures and investigate the relationship between procedure time and lesion detection rate in tertiary endoscopic centers in China.
- Conditions
- Gastroscopy Time, Early Gastric Cancer, Detection Rate
- Trial name
- NCT04602299
- Testing
- Set the minimum time of gastroscopy
- Where
- 2 sites in China
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital
Gastric Cancer, Intestinal Cancer
HFNO Reduces Hypoxia During Sedated Gastroscopy or Colonoscopy in High Risk Patients
The objective of this study is to observe the preventive effects of high flow nasal oxygenation on the incidence of hypoxia during gastroscopy or colonoscopy sedated with propofol in high-risk patients.
- Conditions
- Gastric Cancer, Intestinal Cancer, Intestine Adenoma, Gastritis
- Trial name
- HRISK (NCT05510388)
- Testing
- High-flow nasal cannula oxygenation, Regular nasal cannula oxygenation
- Where
- 2 sites in China
- Volunteers
- 450 people
- Sponsor
- RenJi Hospital
Gastroscopy; Gastric Cancer
Mucolytic Solution Before Upper Endoscopy
Study was designed to evaluate efficacy of mucolytic solution ingested before upper endoscopy on visibility of gastric mucosa.
- Trial name
- NCT02967094
- Testing
- Administration of mucolytic solution before upper endoscopy (Espumisan, ACC long), Administration of water before upper endoscopy
- Where
- Czechia
- Volunteers
- 150 people
- Sponsor
- Vitkovice Hospital
Gastric Cancer, Gastroscopy
Use of Mucolytic Solution Before Upper Endoscopy
The study was designed to evaluate the effectiveness of the maximum dose of mucolytic solution used before upper endoscopy on the visibility of the gastric mucosa
- Trial name
- NCT04641455
- Testing
- Espumisan, N acetylcystein, Water
- Where
- Czechia
- Volunteers
- 120 people
- Sponsor
- Vitkovice Hospital
Early Gastric Cancer, Barrett Esophagus
Linked Color Imaging vs White Light Imaging for Detection of Gastric Cancer Precursors
This study aims to examine the use of Linked Color Imaging in detection of gastric cancer precursors, as well as oesophageal and duodenal lesions.
- Trial name
- NCT03990025
- Testing
- Linked Color Imaging, White Light Imaging
- Where
- 2 sites in Singapore
- Volunteers
- 90 people
- Sponsor
- Changi General Hospital
Stomach Cancer, Diagnosis
Evaluation of the NEOmom® Gastric Video Capsule for Gastric Cancer Screening
Gastric cancer remains a major public health concern, with approximately 6,600 new cases diagnosed each year in France. Despite therapeutic progress, its overall prognosis is still poor: the 5-year survival rate across all stages…
- Conditions
- Stomach Cancer, Diagnosis, Endoscopy of Stomach (Procedure)
- Trial name
- NEOTOGAS (NCT07323186)
- Testing
- Magnetically controlled video capsule endoscopy (MC-VCE)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Nantes University Hospital
Gastric Cancer Stage, Esophageal Cancer
Development and Validation of a Risk Prediction Model for Gastric Retention in Patients Undergoing Sedated Gastroscopy
Gastric retention not only compromises the quality of endoscopic examination but also significantly increases the risk of reflux and aspiration in sedated patients.
- Conditions
- Gastric Cancer Stage, Esophageal Cancer, Gastroparesis
- Trial name
- NCT07104214
- Where
- 3 sites in China
- Volunteers
- 5,000 people
- Sponsor
- Zhejiang University
Gastric Cancer
Web-Mediated Risk Assessment for Endoscopic Screening of Gastric Cancer
Gastric cancer is one of the most common malignancies in China. Early detection is critical for gastric cancer management. However, the diagnosis rate of patients with early gastric cancer is still low.
- Trial name
- NCT03484949
- Testing
- pre-endoscopic screening risk assessment
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- State Key Laboratory of Cancer Biology
Capsule Endoscopy, Cancer of Stomach
Medical Consortium for Screening Upper Gastrointestinal Cancers With Magnetically Controlled Capsule Gastroscopy
The aim of our study was to demonstrate the efficacy and feasibility of the medical consortium for screening upper gastrointestinal cancers with magnetically controlled capsule gastroscopy.
- Conditions
- Capsule Endoscopy, Cancer of Stomach, Cancer of Esophagus, Health Policy
- Trial name
- NCT04032353
- Testing
- Medical Consortium
- Where
- China
- Volunteers
- 10,000 people
- Sponsor
- Yanqing Li
Anastomotic Leak, Gastric Cancer
Anastomotic Leak Testing in Gastrectomy
Anastomotic leak after radical gastrectomy is a serious complication. Intraoperative leak testing was often used to assess the integrity of the anastomosis.
- Conditions
- Anastomotic Leak, Gastric Cancer, Surgery, Testing, Reality
- Trial name
- NCT04292496
- Testing
- Introperative leak testing
- Where
- China
- Volunteers
- 148 people
- Sponsor
- Nanchong Central Hospital
Cirrhosis
Study of Two Fasting Procedures Before Gastroscopy: 6 Hours Versus 2 Hours for Clear Fluids
Upper gastrointestinal endoscopy is the key examination for screening for precancerous and cancerous lesions of the esophagus and stomach.
- Trial name
- GASTROPREP (NCT03706846)
- Testing
- fasting
- Where
- France
- Volunteers
- 70 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Gastric Cancer, Atrophic Gastritis
AG & IM in CA Stomach Protocol
This is a multi-center prospective case control study aiming to compare different methods of risk stratification models in predicting the risk of gastric cancer development.
- Conditions
- Gastric Cancer, Atrophic Gastritis, Intestinal Metaplasia
- Trial name
- NCT04184960
- Testing
- Gastroscopy and gastric biopsies
- Where
- 4 sites in Hong Kong, Japan and 2 more
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Gastritis, Gastric Dysplasia
A Cohort Study of Mobile Capsule Gastroscopy for Gastric Pathologies Screening
The goal of this is to learn about the effectiveness and feasibility of a novel AI- assisted Mobile Capsule Gastroscopy (MCG) system for detecting gastric pathologies in elderly and high-risk populations.
- Conditions
- Gastritis, Gastric Dysplasia, Gastric Ulcer, Gastric Cancer
- Trial name
- NCT07032961
- Testing
- Collect epidemiological, diagnostic, and follow-up data after MCG examination.
- Where
- China
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Nanfang Hospital, Southern Medical University
Gastric Cancer
Screening for Gastric Cancer in High-risk Population
Introduction: Gastric cancer is the world's second largest cause of cancer related deaths. In the Western world, as well as in Israel, this malignancy is less prevalent than colorectal cancer, but has higher morbidity and…
- Trial name
- Stomach (NCT00815113)
- Where
- Israel
- Volunteers
- 80 people
- Sponsor
- Rabin Medical Center
Hypoxia, Gastric Cancer
Efficacy and Safety of Remimazolam Tosylate for Sedation in Gastroscopy
Propofol is the most commonly used intravenous anesthetic for painless gastroscopy, but propofol significantly inhibits the respiratory and circulatory systems.
- Conditions
- Hypoxia, Gastric Cancer, Sedation Complication, Propofol Adverse Reaction
- Trial name
- NCT04727034
- Testing
- Remimazolam tosylate, Propofol
- Where
- 5 sites in China
- Volunteers
- 1,800 people
- Sponsor
- RenJi Hospital