Clinical trials: Gender Minority Stress
Stress Reaction, Sexuality
Effects of Self-Compassion Practice on Stress Reactivity Among Sexual Minority Women
This project will test the ability of brief self-compassion training to attenuate physiological and subjective responses to induced stress among sexual minority women, transgender people, and nonbinary people.
- Conditions
- Stress Reaction, Sexuality, Compassion
- Trial name
- NCT05949060
- Testing
- Compassion Intervention
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Syracuse University
Depression, Anxiety, Alcohol Abuse
Cognitive-Behavioral Therapy for Young Adult Lesbian, Gay and Bisexual: Transdiagnostic Minority Stress Approach
Background: LGB people experience a large number of anxiety and mood disorders, and risk behaviors than heterosexual (Marshall et al., 2011).
- Conditions
- Depression, Anxiety, Alcohol Abuse, Sexual Compulsivity, Unsafe Sex
- Trial name
- NCT03980873
- Testing
- ESTEEM (Effective Sikills to Empower Effective Men)
- Where
- Spain
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- University of the Basque Country (UPV/EHU)
Smoking Cessation, Depression
Adapting and Pilot Testing a Skills-based Smoking Cessation Intervention to Address Developmental and Health-related Stress Among Adults Who Smoke
Smoking remains the leading preventable cause of death in the United States, and there are persistent and significant disparities in tobacco use among transgender and gender diverse (TGD) individuals.
- Conditions
- Smoking Cessation, Depression, Anxiety, Nicotine Dependence
- Trial name
- NCT06654414
- Testing
- PRIDE QUIT, Enhanced Treatment As Usual (ETAU)
- Where
- 3 sites in United States
- Volunteers
- 100 people
- Sponsor
- Massachusetts General Hospital
Sexual and Gender Minorities, Pregnancy Complications
Physical and Mental Health Among Sexual and Gender Minorities During Pregnancy, Birth and Postpartum
Mental illness increases the risk of adverse birth outcomes (e.g. preterm birth), obstetric complications (e.g. emergency caesarean, birth injuries), and birth trauma.
- Conditions
- Sexual and Gender Minorities, Pregnancy Complications, Obstetric Complication, Psychological Trauma
- Trial name
- NCT05354284
- Testing
- online questionnaire
- Where
- Sweden
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Linkoeping University
Alcohol Consumption, Violence, Domestic
Proximal Effects of Alcohol on Same-Sex Intimate Partner Violence
We will recruit sexual and gender minority couples to complete 56 days of daily surveys in order to evaluate (1) the impact of COVID-19 stress and sexual and gender minority stress on heavy episodic drinking and intimate partner…
- Conditions
- Alcohol Consumption, Violence, Domestic, Stress, Psychological, Aggression
- Trial name
- PASSION (NCT04625465)
- Testing
- CBT Text Messaging, Attention Control Text Messaging
- Where
- United States
- Volunteers
- 474 people, healthy volunteers welcome
- Sponsor
- Georgia State University
Gender Dysphoria
Trans Care: An Online Intervention to Reduce Symptoms of Gender Dysphoria
The current project aims to improve the well-being of trans and nonbinary (TNB) individuals through an online intervention (Trans Care) targeting the reduction of symptoms of gender dysphoria.
- Trial name
- NCT05884307
- Testing
- Trans Care Web App
- Where
- United States
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Substance Use, Mental Health
Project Uplift: Substance Use and Mental Health Treatment for Young Sexual and Gender Minorities
This study provides substance use and mental health treatment for young sexual and gender minority adults in Durham and Charlotte, NC and seeks to provide intensive wraparound services that address factors that influence…
- Trial name
- NCT04546061
- Testing
- Project Uplift
- Where
- 2 sites in United States
- Volunteers
- 112 people
- Sponsor
- Duke University
Minority Stress, Acceptability
TAG TEAM - Trans Adolescent Group Therapy
This project will study the effect of the TAG TEAM group CBT program on the mental health of trans and gender diverse adolescents.
- Conditions
- Minority Stress, Acceptability, Psychological Distress, Anxiety
- Trial name
- TAG TEAM (NCT07151079)
- Testing
- Trans Adolescent Group ThErapy for Alleviating Minority stress
- Where
- Australia
- Volunteers
- 142 people
- Sponsor
- Murdoch Childrens Research Institute
Depression, Anxiety
The Mental Health Experiences of Sexual and Gender Minorities Living With Cancer and Their Care Partners
The purpose of this study is to examine relationships between contextual stressors and stress moderators, depression symptom experience, resilience, frailty, and quality of life among older sexual gender minorities cancer…
- Conditions
- Depression, Anxiety, Caregiver Burden, Stress
- Trial name
- SGMC (NCT05866705)
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Depression, Anxiety
Efficacy of a Brief Intervention to Improve Sexual and Gender Minorities' Mental Health: Randomized Controlled Trial.
Experiences of violence, from micro to physical aggressions, have a deleterious impact on mental health. According to the Minority Stress Theory, unfavorable social conditions (such as anticipated and experienced discrimination…
- Conditions
- Depression, Anxiety, Psychological Distress, Social Phobia
- Trial name
- ESCREVA-SE (NCT05349877)
- Testing
- Expressive writing, Self-affirmation
- Where
- Brazil
- Volunteers
- 306 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidade Católica do Rio Grande do Sul
Alcohol Drinking, Violence in Adolescence
The Healthy Families Bright Futures Program
The goal of this clinical trial is to learn about an online group program (Healthy Families Bright Futures program) for LGBTQ+ teens and their caregivers.
- Trial name
- NCT06309134
- Testing
- Healthy Families Bright Futures Program
- Where
- United States
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Colorado Springs
Social Discrimination, Sexual and Gender Minorities
Reducing Daily Stress Among Sexual and Gender Minorities
The purpose of this study is to identify which mindfulness technique, or combination of mindfulness techniques, is most effective at mediating or eliminating stress in emerging adults who are sexual and gender as well as racial…
- Conditions
- Social Discrimination, Sexual and Gender Minorities, Mindfulness
- Trial name
- REDUCE (NCT05131360)
- Testing
- Introduction Only, Purpose Only, Connection Only
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- New York University
Stress (Psychology)
Effectiveness of A Mindfulness-centered Stress Management AI Chatbot to Reduce Stress and Enhance Mental Health Among Men Who Have Sex With Men in China
The goal of this randomized controlled trial is to evaluate the effectiveness of a mindfulness-centered stress management AI chatbot in reducing perceived stress and enhancing mental health among Chinese men who have sex with men…
- Trial name
- MSM (NCT07732621)
- Testing
- Mindfulness-centered stress management AI chatbot, Psychoeducation
- Where
- Hong Kong
- Volunteers
- 76 people
- Sponsor
- The University of Hong Kong
Tobacco Use, Electronic Cigarette Use
Just-in-Time Support for Smoking, Vaping, and Eating Urges During High-Stress Moments Among Gender and Sexual Minority Adults in Dhaka
Gender and sexual minority adults in Bangladesh experience high levels of stigma-related stress. Acute stress can trigger strong, affect-driven urges to smoke, vape, or engage in stress-attributed eating.
- Conditions
- Tobacco Use, Electronic Cigarette Use, Emotional Eating, Stress, Psychological
- Trial name
- NCT07746492
- Testing
- Just-in-Time Adaptive Support Message
- Where
- Bangladesh
- Volunteers
- 115 people
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Stress Disorders, Post-Traumatic, Drinking Heavy
Project QueST 2023: Queer Survivors of Trauma
This study aims to test the initial efficacy of tailored online writing interventions specifically designed for sexual minority women, transgender individuals, and/or nonbinary people to target the primary outcomes: posttraumatic…
- Trial name
- QueST2023 (NCT05569915)
- Testing
- Trauma Expressive Writing, Stigma Expressive Writing, Control
- Where
- United States
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- Syracuse University
Psychological Distress, Stigma, Social
Behavioral Intervention to Reduce Stress Among Black Gender Minority Women
The research objectives of this study are to first, develop a culturally informed community-based intervention with guidance from community members (via focus groups and theater testing) to reduce the effect of chronic stigma…
- Trial name
- NCT05436106
- Testing
- Adaptive Intervention Approach
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Emory University
LGBTQ, Racial Disparities
Family Acceptance Project Online (Pilot RCT)
Research shows that sexual and gender minority youth (SGMY) experience high rates of mental health problems and other challenges (e.g., social, academic).
- Conditions
- LGBTQ, Racial Disparities, Family Relationships, Minority Stress
- Trial name
- FAP-O (NCT06839859)
- Testing
- Family Acceptance Project - Online
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University of Michigan
PTSD
A Comparative Effectiveness Study of PTSD Treatments Among Sexual and Gender Minority Populations
The goal of this clinical trial is see if Cognitive Processing Therapy and STAIR Narrative Therapy work to treat posttraumatic stress disorder (PTSD) among lesbian, gay, bisexual, transgender, queer/questioning, intersex…
- Trial name
- LIFESCAPE (NCT06367764)
- Testing
- Cognitive Processing Therapy, STAIR Narrative Therapy
- Where
- 2 sites in United States
- Volunteers
- 400 people
- Sponsor
- Stanford University