Clinical trials: Gender Related Stress
Alcohol Abstinence
Guanfacine to Reduce Relapse Risk in Women With Alcohol Use Disorder (AUD)
Guanfacine may preferentially reduce craving and improve cognitive control in women with Alcohol Use Disorder (AUD), compared to men.
- Trial name
- NCT03137082
- Testing
- Guanfacine XR 3mgs/daily
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Stony Brook University
Diabetic Nephropathy
Sex-specific Association With Kidney Disease
Oxidative stress is involved in the pathophysiology of diabetic nephropathy. The superoxide-generating nicotinamide adenine dinucleotide phosphate-oxidase 2 (NOX2, encoded by the CYBB gene) and the antioxidant enzyme glutathione…
- Trial name
- NCT01810822
- Where
- Brazil
- Volunteers
- 1,396 people
- Sponsor
- University of Sao Paulo General Hospital
Adolescent Depression
Adolescent Mood During Puberty and Testosterone
Starting at puberty, female adolescents are nearly three-times more likely to develop internalizing disorders, like depression, while male adolescents are two-times more likely to develop externalizing disorders, like attention…
- Trial name
- AMPT (NCT06072677)
- Testing
- Healthy Minds Program
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Depression, Anxiety, Alcohol Abuse
Cognitive-Behavioral Therapy for Young Adult Lesbian, Gay and Bisexual: Transdiagnostic Minority Stress Approach
Background: LGB people experience a large number of anxiety and mood disorders, and risk behaviors than heterosexual (Marshall et al., 2011).
- Conditions
- Depression, Anxiety, Alcohol Abuse, Sexual Compulsivity, Unsafe Sex
- Trial name
- NCT03980873
- Testing
- ESTEEM (Effective Sikills to Empower Effective Men)
- Where
- Spain
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- University of the Basque Country (UPV/EHU)
Smoking Cessation, Depression
Adapting and Pilot Testing a Skills-based Smoking Cessation Intervention to Address Developmental and Health-related Stress Among Adults Who Smoke
Smoking remains the leading preventable cause of death in the United States, and there are persistent and significant disparities in tobacco use among transgender and gender diverse (TGD) individuals.
- Conditions
- Smoking Cessation, Depression, Anxiety, Nicotine Dependence
- Trial name
- NCT06654414
- Testing
- PRIDE QUIT, Enhanced Treatment As Usual (ETAU)
- Where
- 3 sites in United States
- Volunteers
- 100 people
- Sponsor
- Massachusetts General Hospital
Sexual and Gender Minorities, Pregnancy Complications
Physical and Mental Health Among Sexual and Gender Minorities During Pregnancy, Birth and Postpartum
Mental illness increases the risk of adverse birth outcomes (e.g. preterm birth), obstetric complications (e.g. emergency caesarean, birth injuries), and birth trauma.
- Conditions
- Sexual and Gender Minorities, Pregnancy Complications, Obstetric Complication, Psychological Trauma
- Trial name
- NCT05354284
- Testing
- online questionnaire
- Where
- Sweden
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Linkoeping University
Stigma, Social, Gays
An LGBT-Competency Program for Mental Health Professionals in Romania
Lesbian, gay, bisexual and transgender individuals (LGBTI) present increased morbidity compared to the general population, which is attributed to healthcare discrimination and lack of LGBT-specific expertise, especially in…
- Conditions
- Stigma, Social, Gays, Lesbians, Bisexuals
- Trial name
- NCT03602222
- Testing
- Mobile web training LGBT mental health, In-person training LGBT mental health
- Where
- Romania
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Rutgers University
DSD, Hypospadias
Breaking Silence Through Story: A Narrative Medicine Intervention for Parents of Children With Urogenital Conditions
The goal of this clinical trial is to learn whether a journaling intervention can reduce stress and anxiety in parents of children with urogenital conditions (such as differences of sex development and hypospadias).
- Trial name
- NCT06989593
- Testing
- Narrative Medicine Journaling Intervention
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Sarah Schlegel
Posttraumatic Stress Disorder, Shame
NET for SGBV Survivors in Eastern DR Congo
Throughout the last 10 years Narrative Exposure Therapy (NET) has evolved as one of the most effective, culturally sensitive trauma interventions.
- Trial name
- NCT02989987
- Testing
- Narrative Exposure Therapy, Social Support
- Where
- Germany
- Volunteers
- 201 people
- Sponsor
- University of Konstanz
Sexual Risk Behavior, Childhood Sexual Abuse
HIV Prevention and Trauma Treatment for Men Who Have Sex With Men With Childhood Sexual Abuse Histories
Brief Summary: The specific aims of this study are: 1. To test, in a two-arm randomized controlled trial, the efficacy of cognitive processing therapy for sexual risk and posttraumatic symptom severity reduction (CPT-SR) in…
- Conditions
- Sexual Risk Behavior, Childhood Sexual Abuse, Stress Disorders, Post-Traumatic
- Trial name
- THRIVE (NCT01395979)
- Testing
- Cognitive Processing Therapy for Sexual Risk, Supportive Psychotherapy, Sexual Risk Reduction Intervention
- Where
- 3 sites in United States
- Volunteers
- 232 people
- Sponsor
- Massachusetts General Hospital
Obesity, Gender
Work-Related Effects of Heat, Activity, and Fat in Middle Aged Men
Obesity is associated with many undesirable health effects and disease, and middle age is associated with increased risk for disease.
- Conditions
- Obesity, Gender, Problem of Aging
- Trial name
- NCT02532725
- Testing
- Cardiopulmonary Exercise Stress Test, Climatic-Controlled Cardiopulmonary Exercise Stress Test, Body Composition Evaluation
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Freeman-Sheldon Research Group, Inc.
Substance Use Disorders, Posttraumatic Stress Disorder
Trauma Screening/Referral and Interpersonal Violence Prevention for Women with Substance Use Disorders
The purpose of this project is to implement a pilot study to investigate the feasibility and preliminary efficacy of a peer support specialist delivered violence prevention program for women in substance use treatment.
- Conditions
- Substance Use Disorders, Posttraumatic Stress Disorder, Opioid Use Disorder, Violence, Sexual
- Trial name
- NCT06608979
- Testing
- Screening/Referral and Prevention
- Where
- 2 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Clemson University
PostTraumatic Stress Disorder
Effectiveness of Basic Body Awareness Therapy in Post-traumatic Stress Disorders: A Randomized Clinical Trial
The aim of this randomized controlled clinical trial is to assess the effectiveness of Basic Body Awareness Therapy online in patients' survivors of Covid-19, health workers and women suffering from gender based violence…
- Trial name
- BATEP (NCT04396314)
- Testing
- Basic Body Awareness Therapy, Psychological treatment
- Volunteers
- 54 people
- Sponsor
- Universitat de Lleida
Marijuana Dependence
Sex Differences in Attentional Bias in Marijuana-dependent Individuals
The purpose of this study is to explore sex differences in cognitive functioning and responses to marijuana-related items, and to determine whether stress impacts these measures.
- Trial name
- NCT01179425
- Testing
- Cognitive stressor
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Perimenopause, Perimenopause-Related Depression
Intra Ovarian Muse Cell Injection for Perimenopause Symptom Relief and Ovarian Function Restoration (MUSE-OVARY)
This observational study examines the safety and effects of injecting Muse cells (a type of naturally occurring stem like cells found in adult tissues such as fat or bone marrow) directly into the ovaries of women aged 28 to 70…
- Conditions
- Perimenopause, Perimenopause-Related Depression, Premature Ovarian Insufficiency, Premature Ovarian Failure (POF)
- Trial name
- MUSE-OVARY (NCT07511660)
- Where
- Mexico
- Volunteers
- 12 people
- Sponsor
- Healing Hope International
Substance Use, Mental Health
Project Uplift: Substance Use and Mental Health Treatment for Young Sexual and Gender Minorities
This study provides substance use and mental health treatment for young sexual and gender minority adults in Durham and Charlotte, NC and seeks to provide intensive wraparound services that address factors that influence…
- Trial name
- NCT04546061
- Testing
- Project Uplift
- Where
- 2 sites in United States
- Volunteers
- 112 people
- Sponsor
- Duke University
Nicotine Dependence
The Gender-Sex Hormone Interface With Craving & Stress-Related Changes in Smoking
The purpose of the overall parent study is to determine the impact of gender and hormones (estradiol, progesterone, testosterone and cortisol) on responses to stress and smoking cues presented in daily, "real-world" cue…
- Trial name
- SCOR-III (NCT01576874)
- Testing
- Oxytocin
- Where
- United States
- Volunteers
- 144 people
- Sponsor
- Kevin Gray, MD
Pregnancy Gingivitis
The Effect of Periodontal Treatment on Stress and Pregnancy Relationship
There is a relationship between stress and pregnancy gingivitis. This relationship may be double-sided.
- Trial name
- NCT04315532
- Testing
- Non-surgical periodontal treatment, Saliva samples, GCF samples
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Violence, Sexual, Violence, Physical
Online Psychosocial Intervention for Nursing Students Who Experienced Intimate Partner Abuse in Turkey
Intimate partner abuse is very common among university students. Post-traumatic stress disorder is one of the most serious mental diseases caused by intimate partner abuse.The purpose of this study was to assess the impact of an…
- Conditions
- Violence, Sexual, Violence, Physical, Violence, Gender-Based, Violence
- Trial name
- NCT05368779
- Testing
- The internet-based psychosocial intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people
- Sponsor
- Bozok University
Cocaine Dependence
Sex Differences in Progesterone Effects on Responses to Stress and Drug Cues
Cocaine dependence is a chronic, relapsing disorder in which stress/negative mood and exposure to drug-related stimuli or "cues" are associated with high rates of relapse (McKay et al., 1995; O'Brien et al., 1998; R.
- Trial name
- NCT00585520
- Testing
- Progesterone
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Yale University