Clinical trials: General Anesthesia
Hand Hygiene
ProvodineTM Decreases Hand Contamination
The purpose of this study is to see whether Provodine, an FDA approved product, provides long-lasting protection on the hands of staff who provide anesthesia for patients.
- Trial name
- NCT04023682
- Testing
- Provodine Hand Sanitizer
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Sundara Reddy
Anesthesia, General, Fluid Therapy
Management of Intraoperative Fluids in Ambulatory Surgery
This is a single-center prospective randomized control trial (RCT) to determine whether the continuous monitoring of the plethysmographic variability index (PVI) during low-risk surgeries, can be used to optimize the…
- Conditions
- Anesthesia, General, Fluid Therapy, Ambulatory Surgical Procedures
- Trial name
- MIFAS (NCT03193320)
- Testing
- Fluid therapy protocol
- Where
- Venezuela
- Volunteers
- 243 people, healthy volunteers welcome
- Sponsor
- Policlinica Metropolitana
Anesthesia
EEG Studies of Sevoflurane-Induced General Anesthesia
The investigators are performing this research study to find out how and where the anesthetic drugs sevoflurane and ketamine act in the brain.
- Trial name
- NCT03503578
- Testing
- Sevoflurane, Ketamine
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
General Anaesthesia
Comparing Between Air-Q Intubating Laryngeal Airway and Ambu® AuraGain™
The aim of this randomized study is conducted is to evaluate the performance and safety of air-Q intubating laryngeal airway as primary airway device in various short surgical procedure in children compared to Ambu® AuraGain™…
- Trial name
- Nira (NCT03130413)
- Testing
- Ambu Aura Gain supraglottic airway, Air-Q supraglottic airway
- Where
- Malaysia
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
Intubation Complication
Assessment of a Properly Video Stylet Angulation for Orotracheal Intubation
Uses the video stylet with different angulation to assist the orotracheal tube passing the oral cavity, oropharynx and advanced into the trachea
- Trial name
- NCT04735250
- Where
- Taiwan
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Spinal Anesthesia, General Anesthesia
Spinal Versus General Anesthesia for Laparoscopic Cholecystectomy
The purpose of the study is to assess whether spinal anesthesia is or not superior to the standard general anesthesia for fit patients undergoing laparoscopic cholecystectomy.
- Conditions
- Spinal Anesthesia, General Anesthesia, Postoperative Pain
- Trial name
- SALC (NCT00492453)
- Testing
- laparoscopic cholecystectomy
- Where
- Greece
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Postoperative Cognitive Dysfunction
Modafinil to Prevent Postoperative Cognitive Decline
Postoperative cognitive dysfunction is a well-recognized complication of surgery. The aim of the study is to investigate whether cognitive dysfunction is reduced by the use of modafinil as shown by neurocognitive testing.The…
- Trial name
- NCT03914118
- Testing
- Preoperative modafinil + postoperative modafinil
- Volunteers
- 137 people, healthy volunteers welcome
- Sponsor
- The Cooper Health System
Ultrasound Guided L1,L2 Paravertebral Block
Effect of Ultrasound Guided L1,L2 Paravertebral Block in Decrease the Requirements for Hypotensive Drugs During General Anesthesia in Patients Undergoing Hip Surgeries.
The paravertebral block (PVB) is a block of the mixed nerve soon after it exits the intervertebral foramen.(2) It provides intense unilateral analgesia of long duration and has become the primary anesthetic for many…
- Trial name
- NCT03422354
- Testing
- Ultrasound guided PVB with General Aneasthesia, Ultrasound, Paravertebral block
- Where
- Egypt
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Cairo University
Anesthesia
Prediction of Hypotension During Induction of General Anesthesia
Post induction hypotension is closely related to postoperative complications. Patients are at high risk of hypotension due to preexisting hypovolemia and the vasodilatory effects of induction agents.
- Trial name
- NCT06078228
- Testing
- Propofol - Fentanyl- Atracurium
- Where
- Egypt
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Sleep Disturbance, Postoperative Complications
GENERAL vs. REGIONAL ANESTHESIA ON SLEEP QUALITY FOR HIP ARTROPLASTY PATIENTS
Sleep disorders can impair cognitive function, decision-making ability, exercise capacity, and immune system.Sleep disorders, which may occur in the perioperative period as short-term or long-term, affect many patients.
- Conditions
- Sleep Disturbance, Postoperative Complications, Regional Anesthesia Morbidity
- Trial name
- NCT06041711
- Testing
- General anesthesia with propofol induction and sevoflurane maintenance, Regional anesthesia with neuroaxial blockage
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Uludag University
Thoracic, Pain
Rhomboid Intercostal Sub Serratus Plane Block Versus Serratus Anterior Plane Block in Thoractomy
The objective of the current study is to compare the efficacy of the analgesic effect of ultrasound-guided unilateral Rhomboid intercostal and sub serratus plane block (RISS) versus Serratus anterior plane block (SAPB) in…
- Trial name
- NCT06856538
- Testing
- Bupivacain, Ultrasound
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Yasser S Mostafa, MD
Hemodynamic Instability, Anesthesia
Hemodynamic Changes and Propofol Pharmacokinetic Variation During Anesthesia Induction and Knee-chest Positioning
Induction of anesthesia and the knee-chest position are associated with hemodynamic changes that may impact patient outcomes. Changes from baseline in cardiac output and other hemodynamic variables following induction of…
- Conditions
- Hemodynamic Instability, Anesthesia, Surgery
- Trial name
- NCT03961958
- Testing
- Propofol reduction
- Where
- Portugal
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Salamanca
Old Age
Clinical Study of G Protein Biased Μ - Opioid Receptor Agonist Oliceridine for Optimizing Postoperative Analgesia Under General Anesthesia
Traditional opioid analgesia is a treatment method for moderate to severe pain. However, the use of opioid drugs is not without risks.
- Trial name
- NCT06668298
- Testing
- Oliceridine, Sulfentanil
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Henan Provincial People's Hospital
General Anesthetic, Sedation
A Study Evaluating Safety, Pharmacodynamics and Pharmacokinetics of HSK3486 and Etomidate for Induction of Anesthesia in Healthy Male Subjects
This study is designed as an open label, single dose combination of HSK3486 and etomidate in healthy adult male subjects. The study will evaluate the anesthetic/sedation effect of the combination of the 2 drugs and the safety…
- Trial name
- NCT04054063
- Testing
- HSK3486+ etomidate
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Sichuan Haisco Pharmaceutical Group Co., Ltd
Intraoperative Hypotension, Jugular Veins
Internal Jugular Vein Ultrasound and Acute Kidney Injury After Abdominal Surgery
This observational study aims to learn whether changes in the internal jugular vein during anesthesia induction can help predict low blood pressure and kidney injury after surgery. The main questions it aims to answer are: 1.
- Conditions
- Intraoperative Hypotension, Jugular Veins, Hypotension on Induction, General Anesthesia With Propofol
- Trial name
- PRO-JUGULAR (NCT07638306)
- Testing
- Internal Jugular Vein Ultrasound Assesment
- Where
- Romania
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Tîrgu Mureș Emergency Clinical County Hospital, Romania
Pulmonary Embolism
The Clinic Study to Prevent Pulmonary Embolism in Patients With General Anesthesia Operation in Perioperative Period
The purpose of this study is to investigate the prevention of Pulmonary Embolism in Patients who With General Anesthesia Operation in Perioperative Period.
- Trial name
- NCT02460952
- Where
- China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Beijing Chao Yang Hospital
Percutaneous Nephrolithotomy
The Effect of Anesthesia on Pain in Percutaneous Nephrolithotomy
It is aimed to determine the ideal application by determining the effect of different anesthesia methods applied in percutaneous nephrolithotomy surgeries on analgesic consumption and pain level.
- Trial name
- NCT05467878
- Testing
- The anesthesia and analgesia technique preferred by the anesthetist will be recorded.
- Where
- Turkey (Türkiye)
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Tugba Onur
Postoperative Nausea and Vomiting, Sore-throat
Do Throat Pack Used in Dental Treatments Under General Anesthesia of Patients Have an Effect on PONV and Sore Throat?
The aim of this study is to investigate the effect of throat packs on PONV in dental treatments under general anesthesia in special health care needs.
- Conditions
- Postoperative Nausea and Vomiting, Sore-throat, Dental Caries
- Trial name
- NCT06169306
- Testing
- throat pack
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Stress
Evaluation Of Stress Levels Of Pediatric Dentist Performing Dental Treatment In The Operating Room
This study will measure the stress levels of pediatric dentists performing dental treatments under deep sedation and general anesthesia.
- Trial name
- NCT07541508
- Where
- Turkey (Türkiye)
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Combination of General Anesthesia to Spinal and Epidural Techniques
Combination of Spinal-Epidural With General Anesthesia in Patients Undergoing Mega-Liposuction Surgery
The combination of general anesthesia to spinal and epidural techniques (CSEGA) proved to have a synergistic effect, thus, the use of sub-anesthetic doses can provide satisfactory anesthetic and analgesic results.
- Trial name
- NCT05301127
- Testing
- spinal-epidural device
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University