Clinical trials: General Anesthetics
Remimazolam, Desflurane
Remimazolam vs Desflurane for General Anesthesia for Ablation of Arrhythmia
In anesthesia for ablation for cardiac arrhythmias, abrupt hemodynamic changes or fatal arrhythmias can be seen frequently. Remimazolam is a novel ultra-short acting benzodiazepine that provides good hemodynamic stability…
- Conditions
- Remimazolam, Desflurane, Cryoablation, Arrhythmia
- Trial name
- NCT05486377
- Testing
- Remimazolam besylate
- Where
- South Korea
- Volunteers
- 96 people
- Sponsor
- Seoul National University Bundang Hospital
Pregnancy, Cesarean Delivery
Sublingual Misoprostol & Isoflurane During Caesarean Section
Misoprostol would reduce the uterine bleeding after caesarean delivery, without harmful effects on either mother or baby. The investigators postulated that the use of sublingual misoprostol during isoflurane anaesthesia for…
- Trial name
- NCT01466530
- Testing
- Misoprostol
- Where
- Egypt
- Volunteers
- 366 people
- Sponsor
- Mansoura University
Bronchospasm
Bronchospasm During Anesthetic Induction: Study of Clinical Characteristics and Treatments Administered According to Etiology
Bronchospasm during anaesthesia is a rare but potentially life-threatening event. They are classically part of IgE-dependent anaphylaxis but can also occur as an independent clinical entity, triggered by inflammatory factors such…
- Trial name
- NCT05025709
- Where
- France
- Volunteers
- 31 people
- Sponsor
- Central Hospital, Nancy, France
Closed Non Comminuted Long Bone Fractures
Continuous Lornoxicam Infusion for Orthopaedic Surgery
Perioperative continuous infusion of lornoxicam would be an effective and safe regimen to reduce the patient controlled morphine consumption after orthopaedic surgery.
- Trial name
- NCT01718756
- Testing
- Continuous infusion, Scheduled
- Where
- Egypt
- Volunteers
- 96 people
- Sponsor
- Mansoura University
Neuromuscular Blockade
Qualitative Analysis of Barriers to Consistent Use of Neuromuscular Monitoring in General Anaesthesia
Monitoring the degree of neuromuscular blockade in general anaesthesia reduces complications and patient discomfort. However, monitoring is not applied consistently by Danish anaesthesia personnel.
- Trial name
- NCT02239965
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- Herlev Hospital
All Conditions Requiring Non-cardiac Surgery
Impact of Training on the Use of Software and Digital Monitoring Tools During General Anesthesia for Intermediate/Major-risk Surgery on Morbidity and Mortality at 28 Days
Tools such as surgical plethysmographic index, state entropy, train-of-four monitors exist to optimize the conduct of general anesthesia in intermediate and major risk surgery as defined by the 2022 European Society of Cardiology…
- Trial name
- AoA QUALITY (NCT06111248)
- Testing
- Training
- Where
- France
- Volunteers
- 1,028 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Awareness During General Anesthesia
Is Density Spectral Array Display Along With Bispectral Index Superior to the Display of Bispectral Index Alone
A study to evaluate the use of density spectral array display in comparison with Bispectral index in a clinical setting.
- Trial name
- DSA-Light (NCT07232160)
- Testing
- Depth of anesthesia monitoring using processed EEG
- Where
- Australia
- Volunteers
- 70 people
- Sponsor
- The University of Queensland
Strabismus, Anesthesia, General
The Effect of Anaesthesia Depth on Oculo-cardiac Reflex
This study was designed to determine the effect of the depth of anesthesia on the oculocardiac reflex (OCR) during pediatric strabismus surgery.
- Trial name
- NCT02379546
- Testing
- Desflurane, Bispectral index monitoring
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Tokat Gaziosmanpasa University
Anesthetic, Sevoflurane
Sevoflurane Concentrations in Children
The sevoflurane concentrations (as well as vital signs, child's date of birth, type of surgery) will be recorded during the first 10 minutes of anesthesia.
- Conditions
- Anesthetic, Sevoflurane, Age
- Trial name
- NCT06510803
- Testing
- The washin of sevoflurane in the GE Ohmeda workstation
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- State University of New York at Buffalo
Postoperative Pain, Open Abdominal Surgery
Erector Spinae Plane Block for Pain Control After Open Abdominal Surgery
his randomized controlled trial aims to evaluate the efficacy of the bilateral erector spinae plane (ESP) block in reducing postoperative opioid consumption in patients undergoing open abdominal surgeries under general anesthesia
- Trial name
- NCT07479069
- Testing
- Bilateral Erector Spinae Plane (ESP) Block, Standard Postoperative Analgesia
- Where
- Pakistan
- Volunteers
- 46 people
- Sponsor
- Fatima Memorial Hospital
General Anesthesia
Gastric Ultrasound in Paediatric Anaesthesia
Anesthesia for emergency surgery is a situation at risk of pulmonary aspiration of gastric contents. It has been previously reported that bedside two-dimensional ultrasonography can be a useful tool for anesthesiologists to…
- Trial name
- ECHOGASTRO (NCT02584348)
- Testing
- Gastric ultrasound
- Where
- France
- Volunteers
- 146 people
- Sponsor
- Hospices Civils de Lyon
Propofol Adverse Reaction
Propofol Induction Based on Lean Body Weight on the Depth of Anesthesia
Propofol has significant hemodynamic side effects. It is a lipophilic agent and is generally used at a dose of 2-2.5 mg/kg for induction.
- Trial name
- propofol (NCT06862349)
- Testing
- Group T received propofol at a dose of 2-2.5 mg/kg based on total body weight, Group L received propofol at 2-2,5mg/kg dose based on lean body weight, which was calculated from CT imaging by a radiologist.
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Ankara City Hospital Bilkent
Intraoperative Lung Protective Ventilation
Intraoperative Lung Protective Ventilation in Czech Republic
This questionnaire-based study aims to evaluate the adherence to and current clinical practices regarding intraoperative lung-protective ventilation (IOLPV) among anesthesiologists in the Czech Republic.
- Trial name
- IOLPVCZ (NCT07282899)
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Masarykova Nemocnice v Usti nad Labem, Krajska Zdravotni a.s.
Smooth Extubation
Smooth Extubation With Magnesium Sulphate for General Anesthesia With Endotracheal Intubation
Tracheal extubation is a critical event in the anaesthetic management of patients undergoing general anaesthesia with endotracheal intubation for elective procedures.
- Trial name
- NCT04617652
- Testing
- Magnesium sulfate, Normal saline
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Fayoum University Hospital
Rotator Cuff Tear, Shoulder Surgery
Interscalene Brachial Plexus Block and Early Wound-Related Symptoms After Open Rotator Cuff Repair
This exploratory randomized controlled trial evaluated the association of interscalene brachial plexus block (ISB) with early postoperative wound-related symptom scores and perioperative biomarker responses in patients undergoing…
- Conditions
- Rotator Cuff Tear, Shoulder Surgery, Postoperative Recovery
- Trial name
- NCT05499897
- Testing
- Ultrasound-Guided Interscalene Brachial Plexus Block, General Anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Yuzuncu Yil University
Airway Management, Obesity
Comparison of Air QTM Intubating Airway Versus Ambu-Aura Intubating Laryngeal Mask
Supraglottic airway devices are important tools for airway management. Supraglottic airway devices have been introduced into brief surgical interventions because they are less invasive than intubation and safer than mask to…
- Trial name
- NCT04195035
- Testing
- Air-Q intubating laryngeal airway, Ambu-Aura intubating laryngeal mask
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Post-induction Hypotension (PIH)
Echocardiography-derived Pre-induction Hemodynamic Phenotypes and Post-induction Hypotension: an Exploratory Clustering Analysis
This study evaluated the occurrence of post-induction hypotension (PIH) in patients undergoing elective surgery under general anesthesia. PIH is a common perioperative complication associated with adverse outcomes.
- Trial name
- NCT07509255
- Where
- Morocco
- Volunteers
- 64 people
- Sponsor
- Avicenna Military Hospital
Carbon Footprint in Anesthetic
Life Cycle Assessment of Different Types of Anesthetic
Following Ethics approval, all adult patients undergoing surgery to fix the wrist fracture will be approached and consent to undergo this study.
- Trial name
- NCT05385367
- Testing
- Regional anesthetic, General anesthetic, Combined general anesthetic and regional anesthetic
- Where
- 2 sites in Canada
- Volunteers
- 30 people
- Sponsor
- University of Alberta
Cerebral Hypoxia, Postoperative Delirium
Sevoflurane Decreases the Risk of Postoperative Delirium After Cerebral Hypoxemia During Surgery
The aim of this study is to distinguish possible differences in frequency of delirium after Volatile Induction and Maintenance of Anesthesia and Total Intravenous Anesthesia in case of undeliberate cerebral desaturation during…
- Trial name
- NCT02133638
- Testing
- Sevoflurane, Propofol
- Where
- Russia
- Volunteers
- 130 people
- Sponsor
- Negovsky Reanimatology Research Institute
Anesthesia, General
Muscle Relaxants and Laryngeal Local Anesthetics for Laryngeal Mask Airway Insertion Decreasing Propofol in Elderly
Laryngeal mask airway (LMA) is currently the most widely used supraglottic airway device with advantages of simple and fast placement, reduced anesthesia drug use, more stable hemodynamics, and less throat discomfort after…
- Trial name
- LMA (NCT05310110)
- Testing
- 10% lidocaine spray, Cisatracurium, Propofol
- Where
- Taiwan
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital