Clinical trials: General Health
Depression, Generalized Anxiety
The Mental Health Status of the General Population During the COVID-19 Pandemic and Its Association With Adherence to Government-initiated Non-pharmacological Epidemiological Interventions (NPI's)
This study seeks to investigate the levels of common psychopathology symptoms (i.e., depression and generalized anxiety) in a general population during the strict social distancing government-initiated non-pharmacological…
- Conditions
- Depression, Generalized Anxiety, Adherence to Non-pharmacological Epidemiological Interventions (NPIs)
- Trial name
- NCT04356365
- Testing
- Cross-sectional study investigating the association of NPIs with mental health
- Where
- Norway
- Volunteers
- 10,084 people, healthy volunteers welcome
- Sponsor
- University of Oslo
Zinc Deficiency, Mother and Child Malnutrition
Multi-Omic Profiling of a Zinc-Biofortified Maize Intervention in Guatemalan Mothers and Children
A trial evaluating the systemic and ecological impact of zinc-biofortified maize consumption on cellular zinc status, inflammatory biomarkers, and gut microbiota composition in a cohort of Guatemalan mothers and children.
- Trial name
- NCT07585318
- Testing
- F3 Biofortified Maize, Conventional Maize
- Where
- Guatemala
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Institute of Nutrition of Central America and Panama
Steatosis of Liver, NASH - Nonalcoholic Steatohepatitis
The Liver in the World Trade Center Health Program General Responder Cohort and Controls
This project investigates whether exposure to the World Trade Center Attack is a risk factor for liver injury.
- Trial name
- NCT03858920
- Testing
- Fibroscan of Liver, Low-dose non-contrast CT
- Where
- United States
- Volunteers
- 340 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Treatment Adherence and Compliance, Anxiety
Global Controlled Trial on Effects of an Online Self-Help Program for of Ambitious Altruists on Their Mental Health, Wellbeing, and Productivity: Comparing Versions With IFS vs. CBT, Buddy- vs. Group-, Standard- vs. Minimum-Guidance Intensity.
This study aims to compare different versions of a 16-week online self-help program in terms of their effect on self-assessed mental health, well-being, and productivity.
- Conditions
- Treatment Adherence and Compliance, Anxiety, Depression, Mental Health Issue
- Trial name
- CT_DoBetter (NCT06442072)
- Testing
- guided online self-help program
- Where
- Netherlands
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Rethink Wellbeing
Gender-Based Violence, Intimate Partner Violence
GBV Response Training for Health Assistant Students in Nepal
This study evaluated a six-day Gender-Based Violence (GBV) response training for PCL General Medicine (Health Assistant) students in Nepal.
- Conditions
- Gender-Based Violence, Intimate Partner Violence, Health Professions Education
- Trial name
- GBV-HA-RT (NCT07851883)
- Testing
- Six-Day GBV Response Training (WHO LIVES-based)
- Where
- Nepal
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Axon Infotech Research Academy Pvt. Ltd.
Health Behavior
Health Behavior Change During COVID-19 Pandemic
This study aims at investigating handwashing behavior during COVID-19 pandemic. It was hypothesized that social-cognitive and emotional predictors as well as COVID-19 morbidity and mortality rates within the country would be…
- Trial name
- NCT04367337
- Testing
- No intervention
- Where
- 14 sites in Australia, Canada and 12 more
- Volunteers
- 6,079 people, healthy volunteers welcome
- Sponsor
- University of Social Sciences and Humanities, Warsaw
Smoking Cessation
Social Determinants and Smoking Cessation
The goal of this study is to learn about the influence of the social and physical environment on smoking cessation (quitting smoking) among smokers.
- Trial name
- NCT01310842
- Testing
- Questionnaires, Nicotine Patch Therapy, Counseling Sessions
- Where
- United States
- Volunteers
- 329 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Coronary Artery Calcification, Arterial Stiffness
The InterVitaminK Trial - Effects of Vitamin K Supplementation on Cardiovascular, Metabolic, and Bone Health
The purpose of this study is to examine the effect of menaquinone-7 (MK-7) supplementation on cardiovascular, metabolic, and bone health.
- Trial name
- InterVitaminK (NCT05259046)
- Testing
- Menaquinone-7 (MK-7) tablet (333 µg)
- Where
- Denmark
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Bispebjerg Hospital
Hypercholesterolemia, Flatulence
Fabulous Fibre Study - Effect of Wheat Bran Extract on Gut and General Health in Healthy Aging Subjects (FFS)
This is a placebo controlled, cross-over, randomized, double blinded study. The intervention food products will be taken as diet prebiotic supplements: 1.
- Conditions
- Hypercholesterolemia, Flatulence, Intestinal Diseases
- Trial name
- FFS (NCT02693782)
- Testing
- Fibre supplement
- Where
- United Kingdom
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Aberdeen
Child Behavior Problem, Mental Health Issue
Supporting Parents & Kids Through Lockdown Experiences (SPARKLE).
Throughout the COVID-19 pandemic, reduced access to childcare, money- and health-related worries and extended confinement and social isolation have placed great pressure on many families.
- Trial name
- SPARKLE (NCT04786080)
- Testing
- Parent Positive
- Where
- United Kingdom
- Volunteers
- 646 people, healthy volunteers welcome
- Sponsor
- King's College London
Alcohol Consumption
Impact of Alcohol Consumption on Use of Health Care Resources
The prevalence of alcohol-related disorders in the general population is around 10%. The relationship between the use of healthcare services, costs and the amount of alcohol consumed by the general population is unknown.
- Trial name
- NCT02343874
- Testing
- No intervention
- Where
- Spain
- Volunteers
- 1,911,771 people, healthy volunteers welcome
- Sponsor
- Hospital Clinic of Barcelona
Mental Health, Therapeutics
Lay Therapist Effectiveness With Displaced Persons Kurdish Iraq
Negative mental health effects of war exposure and displacement are pervasive, but many displaced persons and refugees in low-and-middle income countries lack access to evidence-based treatments.
- Trial name
- NCT04684810
- Testing
- Community Lay Therapist-Administered EBT
- Where
- Iraq
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
Gender Relations, Reproductive Health
Global Early Adolescent Study - Kinshasa
The Global Early Adolescent Study (GEAS) is the first international study exploring how gender norms evolve over time and inform a spectrum of adolescent health outcomes, including sexual and mental health, through the adolescent…
- Trial name
- GEAS_KI (NCT03610568)
- Testing
- Growing up GREAT! Intervention
- Where
- Democratic Republic of the Congo
- Volunteers
- 2,862 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Heart Rate, All-day Steps
Assessing the Effect of Cool Roofs on Health Using Smartwatches
Ambient air temperatures in Asian, Latin American, African, and Pacific climate hotspots have broken record highs in 2024. Solutions are needed to build heat resilience in communities and adapt to increasing heat from climate…
- Conditions
- Heart Rate, All-day Steps, Distance Walked, Active Minutes
- Trial name
- REFLECT (NCT06579963)
- Testing
- Cool roof
- Where
- 4 sites in Burkina Faso, India and 2 more
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Aditi Bunker
Childhood Obesity, Overweight (BMI > 25)
Weight Status, Resilience, and Quality of Life in Indian Children
A school-based cross-sectional study that aims to generate context-specific evidence on how weight status is related to resilience, health behaviour, and quality of life among Indian adolescents.
- Conditions
- Childhood Obesity, Overweight (BMI > 25), Underweight
- Trial name
- NCT05648045
- Where
- 16 sites in India
- Volunteers
- 720 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Suicide, Depression
Adaptation of a French E-health Tool for Suicide Prevention in Young Populations
"France's suicide rate is among the highest in Europe, with the young among the more at risk. Several European projects have demonstrated the effectiveness of using e-tools in suicide prevention particularly for hard-to-reach…
- Conditions
- Suicide, Depression, Psychological Distress, Anxiety Disorders
- Trial name
- E-psYouth (NCT04946955)
- Testing
- Application and website with or without promotion
- Where
- France
- Volunteers
- 12,000,000 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Depression - Major Depressive Disorder, Anxiety
Singula Phase 0.1 Primary Care Pilot
This prospective, single-arm, observational pilot study evaluates a clinical decision support system developed by Singula Health for use in primary care.
- Trial name
- NCT07834684
- Where
- 2 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Singula Health, Inc.
Stress, Mental Health and General Well-being
Biomarkers of Environment Sensitivity
Most of the common mental disorders are heritable to a certain extent but environmental factors have an important role influencing whether the disorder will develop or not. These factors can be negative (e.g.
- Trial name
- NCT07594080
- Testing
- Williams Life Skills Stress Management Training
- Where
- Hungary
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Semmelweis University
Menopause, Overweight
Epidemiology of Urinary Functional Disorders in Women of 40 and More
Assess prevalence of urinary functional disorders in women of 40 and more, visiting a general practitioner, occupational medicine or health examination center in Puy-de-Dôme.
- Conditions
- Menopause, Overweight, Surgical Antecedent, Gestity
- Trial name
- NCT03586765
- Testing
- Female urinary incontinence
- Where
- France
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Human Papilloma Virus
Increasing Human Papillomavirus (HPV) Vaccine Uptake Via General Health Messaging
Background: Prevention of cervical cancer and genital warts could be achieved by immunization with the prophylactic human papillomavirus (HPV) vaccines commercially available. However, in the U.S.
- Trial name
- NCT03759236
- Testing
- Health Messaging via SMS, CDC Health Pamphlets
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles