Clinical trials: Generalized Anxiety Disorder
Generalized Anxiety Disorder (GAD)
MRI-Guided Accelerated cTBS for Generalized Anxiety Disorder
Generalized Anxiety Disorder (GAD) is a common psychiatric disorder associated with persistent anxiety, functional impairment, and incomplete response to existing treatments.
- Trial name
- NCT07640945
- Testing
- continuous theta burst stimulation(cTBS)
- Volunteers
- 75 people
- Sponsor
- Central South University
Cholecystectomy, Laparoscopic, Anxiety
Effects of VR on Preanesthetic Anxiety
In today's medical environment, laparoscopic cholecystectomy is a common procedure for treating gallbladder diseases, offering advantages such as smaller incisions and faster recovery.
- Conditions
- Cholecystectomy, Laparoscopic, Anxiety, Uncertainty, Perioperative Period
- Trial name
- NCT07656246
- Testing
- Virtual Reality Intervention
- Where
- Taiwan
- Volunteers
- 200 people
- Sponsor
- Mackay Memorial Hospital
Dementia, Alzheimer Disease
Effectiveness of a 3-month Individual Reminiscence Therapy Program in Older Adults With Alzheimer's Disease
This research aims to evaluate the effectiveness of individual Reminiscence Therapy (RT) program, using a simple reminiscence format, to improve the overall cognitive function, mood, and quality of life (QoL) of older adults with…
- Conditions
- Dementia, Alzheimer Disease, Cognitive Impairment
- Trial name
- NCT06812442
- Testing
- Reminiscence therapy
- Where
- 4 sites in Portugal
- Volunteers
- 40 people
- Sponsor
- Rsocialform - Geriatria, Lda
Anxiety Disorders
Study Of Remission In Patients Treated For Generalized Anxiety Disorder
The aim of the study is to assess the remission rates in patients treated for generalized anxiety disorder in primary and specialized care.
- Trial name
- NCT01788553
- Testing
- remission prevalence of generalized anxiety disorder
- Where
- Belgium
- Volunteers
- 750 people
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Generalized Anxious Disorders
Psycho-biological Substrates of Therapeutic Benefit of Thermal Cure on Generalized Anxiety Disorders
Multicenter study comparing paroxetine (n=30) versus thermal cure (n=30) in patients with a diagnosis of Generalised Anxiety Disorders
- Trial name
- Insula-TOP (NCT03277339)
- Testing
- Paroxetine, Thermal cure
- Where
- 2 sites in France
- Volunteers
- 52 people
- Sponsor
- Centre Hospitalier Henri Laborit
Generalized Anxiety Disorder
Computerized Cognitive Training in Middle-Aged Adults With Generalized Anxiety Disorder: A Pilot Study
The purpose of this research is to look at the effects of computerized cognitive training on anxiety, sleep, mental abilities (cognition), and other aspects of daytime functioning, such as arousal.
- Trial name
- COGMA (NCT04421690)
- Testing
- Cognitive Training, Trivia Training
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Generalized Anxiety Disorder, Social Anxiety Disorder
Attention Retraining for Anxiety Disorder Patients Resistent to Antidepressants
The objective of this project is to test the combination of active or placebo Attentional Bias Modification Treatment (ABMT) to usual treatment for anxiety disorder patients resistant to antidepressants.
- Conditions
- Generalized Anxiety Disorder, Social Anxiety Disorder, Panic Disorder
- Trial name
- NCT01906268
- Testing
- Attentional Bias Modification Treatment (ABMT) - Active
- Where
- 2 sites in Brazil
- Volunteers
- 60 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Diabetes Mellitus, Type 1
GAD-Alum (Diamyd) Administered Into Lymph Nodes in Combination With Vitamin D in Type 1 Diabetes (DIAGNODE-1)
The objectives of the main study is to: Evaluate the safety of giving GAD-Alum (Glutamic acid decarboxylase) (Diamyd) directly into lymph glands in combination with an oral vitamin D regimen Evaluate how the above mentioned…
- Trial name
- DIAGNODE (NCT02352974)
- Testing
- GAD-Alum, Vitamin D
- Where
- Sweden
- Volunteers
- 12 people
- Sponsor
- Johnny Ludvigsson
Dementia, Neurocognitive Disorders
Cognitive Stimulation in Older Adults With Alzheimer's Disease
This multicentre study, employing a randomised controlled repeated measures experimental design, will be conducted in several Portuguese institutions that provide care and support services for older adults diagnosed with mild to…
- Conditions
- Dementia, Neurocognitive Disorders, Cognitive Impairment, Cognitive Dysfunction
- Trial name
- NCT07041008
- Testing
- Digital intervention, Physical/Analogue Intervention
- Where
- 39 sites in Portugal
- Volunteers
- 514 people
- Sponsor
- Rsocialform - Geriatria, Lda
Cannabis Use Disorder, Anxiety
Use of a Generative AI (Gen-AI) Chatbot for Anxiety and Depression Among Persons With Cannabis Use
The goal of this clinical trial is to learn if Therabot-CALM (Cannabis, Anxiety, Low Mood) has acceptability among users and could work to improve the symptoms of persons with cannabis use disorder and anxiety and/or depression.
- Conditions
- Cannabis Use Disorder, Anxiety, Depression, Anxiety, Depression - Major Depressive Disorder
- Trial name
- NCT06920238
- Testing
- Therabot-CALM
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Trustees of Dartmouth College
Generalized Anxiety Disorder
Locating Regions of Interest in Generalized Anxiety Disorder Using Function Magnetic Resonance Imaging (fMRI)
The investigators are seeking to locate the brain regions of interest in generalized anxiety disorder (GAD) using both structural (sMRI) and functional magnetic resonance imaging (fMRI).
- Trial name
- fMRI (NCT01607710)
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Hartford Hospital
Type 1 Diabetes Mellitus
A Phase III Study to Investigate the Impact of Diamyd in Patients Newly Diagnosed With Type 1 Diabetes (EU)
The purpose of this study is to determine whether Diamyd (rhGAD65 formulated in alum) is effective in preserving the body's own insulin producing capacity in patients recently diagnosed with type 1 diabetes.
- Trial name
- NCT00723411
- Testing
- rhGAD65
- Where
- 70 sites in Finland, France and 7 more
- Volunteers
- 334 people
- Sponsor
- Diamyd Therapeutics AB
Dysthymic Disorder
Desvenlafaxine Monotherapy in Dysthymia
This multi-centred study will be conducted at two centres. The design will be an open label, flexible-dose study. This investigation will evaluate the efficacy of Desvenlafaxine monotherapy for patients who meet diagnostic…
- Trial name
- NCT01948895
- Testing
- Desvenlafaxine
- Where
- 2 sites in Canada
- Volunteers
- 30 people
- Sponsor
- Centre for Addiction and Mental Health
Generalized Anxiety Disorder (GAD), Major Depressive Disorder (MDD)
Internet-Based Cognitive Behavioral Therapy With Treatment as Usual for Generalized Anxiety Disorder and Major Depressive Disorder in Taiwan (ICBT-TW)
This study aims to evaluate the effectiveness of internet-based cognitive behavioral therapy (ICBT) combined with treatment as usual (TAU) for adults diagnosed with generalized anxiety disorder (GAD) or major depressive disorder…
- Trial name
- ICBT-TW (NCT07177365)
- Testing
- Internet-Based Cognitive Behavioral Therapy (ICBT), Treatment as Usual (TAU) Only
- Volunteers
- 120 people
- Sponsor
- National Health Research Institutes, Taiwan
Anxiety Disorder Generalized
A Study to Assess the Efficacy and Safety of CD-008-0045 in Patients With Generalized Anxiety Disorder
This is a multicenter, randomized, double-blind, placebo- and active-controlled study to assess the efficacy and safety of CD-008-0045 in patients with generalized anxiety disorder (GAD).
- Trial name
- NCT04598867
- Testing
- CD-008-0045, Afobazol
- Volunteers
- 200 people
- Sponsor
- ChemRar Research and Development Institute, LLC
Anxiety Disorders Generalized
A Pilot fMRI Study of TMS in Late-Life Severe Worry
Investigators will test a novel intervention through experimental therapeutic approach using fMRI-directed Intermittent Theta Burst Stimulation (iTBS), a high frequency TMS paradigm, for the treatment of severe, uncontrollable…
- Trial name
- TINA (NCT03577106)
- Testing
- Transcranial magnetic stimulation (TMS)
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Carmen Andreescu
Generalized Anxiety Disorder
Long Term Chamomile Therapy for Anxiety
Prior research has shown that chamomile may be an effective, short-term anti-anxiety treatment. This study will examine the initial and long-term benefits of chamomile extract therapy for the prevention of recurrent anxiety…
- Trial name
- NCT01072344
- Testing
- Chamomile (Matricaria recutita)
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- University of Pennsylvania
Anxiety Disorders, Generalized Anxiety Disorder
Motivational Interviewing and Cognitive Behavioural Therapy for Generalized Anxiety Disorder
The current study examines whether change-readiness, and consequently treatment outcome, can be enhanced in Cognitive Behavioral Therapy (CBT) for severe Generalized Anxiety Disorder (GAD) by adding a brief course of Motivational…
- Trial name
- NCT01488799
- Testing
- Motivational Interviewing and Cognitive Behavioural Therapy
- Where
- 2 sites in Canada
- Volunteers
- 85 people
- Sponsor
- York University
Generalized Anxiety, Worry
Training Mental Habits Study
Generalized Anxiety Disorder (GAD) is a chronic condition whose hallmark feature is excessive and uncontrollable worry (American Psychiatric Association, 2013).
- Trial name
- NCT03205332
- Testing
- Concreteness Training
- Where
- Canada
- Volunteers
- 121 people
- Sponsor
- Toronto Metropolitan University
Depressive Disorder, Major
Identifying Very Early Response to Seroquel Extended Release (XR) Augmentation for Major Depressive Disorder
The proposed study is for a 6 week open-label clinical trial in which Seroquel XR is added to a selective serotonin reuptake inhibitor (SSRI) medication for the treatment of depressive and/or anxiety symptoms.
- Trial name
- NCT00892463
- Testing
- Quetiapine (Seroquel) XR
- Where
- Canada
- Volunteers
- 26 people
- Sponsor
- Sunnybrook Health Sciences Centre