Clinical trials: Genital Infection Female
Treponema Pallidum Infection, Chlamydia Trachomatis Infection
Improving Maternal and Child Health Through Point-of-care STI Testing
The goal of this clinical trial is to learn if point-of-care tests (POCTs) for sexually transmitted infections (STIs) improve the timely treatment of syphilis, chlamydia, gonorrhea, and trichomonas in pregnant women.
- Conditions
- Treponema Pallidum Infection, Chlamydia Trachomatis Infection, Neisseria Gonorrheae Infection, Trichomonas Vaginalis Vaginitis
- Trial name
- MATCH-POINT (NCT07290439)
- Testing
- Point-of-care STI tests, Standard of care STI testing
- Where
- United States
- Volunteers
- 756 people, healthy volunteers welcome
- Sponsor
- Emory University
HIV/AIDS
Developing and Examining Evidenced-Based HIV Testing Messages
The goals of this study are to: 1. Develop a HIV test message tailored for African American women. A generic non-tailored message will be developed as well for comparison.
- Trial name
- NCT03433053
- Testing
- HIV Testing Message Intervention, Control
- Where
- United States
- Volunteers
- 141 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Contraceptive Usage, Opioid Dependence
Improving Effective Contraceptive Use Among Opioid-maintained Women: Stage II
Nearly 9 of every 10 pregnant opioid-dependent women report that the current pregnancy was unintended and the majority of non-pregnant opioid-maintained women do not use contraception or use less effective methods like condoms.
- Trial name
- NCT02411357
- Testing
- Treatment as usual, WHO contraception protocol, Incentives
- Where
- United States
- Volunteers
- 138 people
- Sponsor
- University of Vermont
Sexually Transmitted Infections, HIV Infections
Sexually Transmitted Infections Among African American Women Who Have Sex With Women
The purpose of this study is to determine the rates of sexually transmitted infections (STI) among a group of African American women who have sex with women (AA WSW).
- Trial name
- WSW (NCT01043081)
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- University of Mississippi Medical Center
Human Immunodeficiency Virus (HIV) Infection
Pharmacokinetics, Safety And Toleration Of Maraviroc Administered To Subjects With Various Degrees Of Renal Impaired And Normal Renal Function
The purpose of this study is to assess whether a dosing adjustment is needed in patients with renal impairment.
- Trial name
- NCT00717067
- Testing
- Maraviroc, Ritonavir, Saquinavir
- Where
- 2 sites in Germany
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- ViiV Healthcare
Female Genital Warts
The Psychosocial and Economic Burden of Genital Warts
Considering the importance of HPV(human papilomavirus) and related diseases in Brazil, and the lack of studies about both the economic and the psychosocial burden of these diseases, BEMFAM, a Brazilian non-governmental…
- Trial name
- GWburden (NCT01520194)
- Testing
- women attending reproductive health clinics, medical records
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- BEMFAM-Bem Estar Familiar
Papillomavirus Infections
Self-collected Swabs for HPV Testing in 18-24 Year Old Women
The purpose of this study is to compare methods for transporting self-collected swabs for HPV testing in 18-24 year old women and to look at risk factors for HPV infection in 18-24 year old women.
- Trial name
- DRY (NCT01101828)
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Washington
Vaginal Flora
Longitudinal Study of Vaginal Flora
Bacterial vaginosis is a syndrome manifested by adverse alterations in vaginal microbial flora. It is present in 10 to 25% of women in the general population, and is the most common vaginal infection.
- Trial name
- NCT00340275
- Where
- United States
- Volunteers
- 5,500 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Bacterial Vaginosis
Validation of a Novel Diagnostic, Prognostic Assay for Bacterial Vaginosis
Bacterial vaginosis (BV) is the commonest form of vaginitis worldwide, affecting millions of women. Unfortunately, recurrence rates of symptomatic BV remain extremely high, 30% at three months and 70-80% within a year.
- Trial name
- BV-LbRC (NCT02185456)
- Testing
- 750 mg metronidazole/ 200 mg miconazole vaginal suppository, Standard of care
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Wayne State University
Pregnant HIV Positive Women
A Prospective, Observational Study of HIV-Infected Pregnant Women and Their Infants at Clinical Sites in Latin American and Caribbean Countries
By the end of 1999, it was estimated that 1.2 million children were living with HIV infection. During 1999 alone, 600,000 children were newly infected with HIV, mostly in less-developed countries.
- Trial name
- NCT00341302
- Where
- 12 sites in Argentina, Brazil and 1 more
- Volunteers
- 3,554 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Primary Ovarian Insufficiency, Cardiovascular Diseases
Associations of Combinations of Single-nucleotide Polymorphisms in Women With Premature Ovarian Failure
Research objective. To study the associations between combinations of single nucleotide polymorphisms and behavioural risk factors with non-communicable diseases and adverse outcomes in women with premature ovarian failure.
- Conditions
- Primary Ovarian Insufficiency, Cardiovascular Diseases, Menopause, Premature, Coronary Disease
- Trial name
- NCT04943354
- Testing
- Taking a person's venous blood
- Where
- Russia
- Volunteers
- 238 people, healthy volunteers welcome
- Sponsor
- Ryazan State Medical University
Sexually Transmitted Infections (Not HIV or Hepatitis), Premature Birth
Genital Tract Infections, the Vaginal Microbiome and Gestational Age at Birth Among Pregnant Women in South Africa
This cohort study plans to investigate associations between the presence of multiple lower genital tract microorganisms in pregnancy and gestational age at birth.
- Conditions
- Sexually Transmitted Infections (Not HIV or Hepatitis), Premature Birth, Pregnancy; Infection, Microbial Colonization
- Trial name
- NCT06131749
- Testing
- No intervention
- Where
- South Africa
- Volunteers
- 603 people
- Sponsor
- University of Bern
HPV Vaccination, Uptake Vaccination
PREVENT Pilot HPV - Related Cancers Trial
This study will serve as one of the first to develop and test the effectiveness of strategies to promote HPV vaccination among diverse rural parents and caregivers of children ages 9-17 years in the Mountain West.
- Conditions
- HPV Vaccination, Uptake Vaccination, Series Completion
- Trial name
- NCT06738355
- Testing
- PREVENT
- Where
- United States
- Volunteers
- 335 people, healthy volunteers welcome
- Sponsor
- University of Utah
Human Papillomavirus, Cervical Intraepithelial Neoplasia
Evaluating the 2-dose Immunization Schedule of Human Papillomavirus (HPV)-16/18 in Adolescent Females
To evaluate the immune non-inferiority, as measured by antibody responses, of a 2-dose immunization schedule (0, 6 months) of recombinant human papillomavirus virus-like particle vaccine (type 16 and 18 L1 proteins, yeast)…
- Conditions
- Human Papillomavirus, Cervical Intraepithelial Neoplasia, Persistent Infection
- Trial name
- NCT02740777
- Testing
- HPV-16/18 vaccine
- Where
- 2 sites in China
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- Shanghai Zerun Biotechnology Co.,Ltd
HPV Infections, Precancerous Disease of the Cervix
Primary and Secondary Prevention of Human Papillomavirus (HPV) Disease in China
In a hospital-based multi-center study in China, HPV 16 was found to be the predominant type (72.9%) in cervical cancer, followed by HPV 18(8.0%) which indicated that if the HPV prophylactic vaccine are wisely applied in China…
- Conditions
- HPV Infections, Precancerous Disease of the Cervix, Cervical Cancer, HPV Related Diseases
- Trial name
- NCT01021904
- Testing
- Gardasil (VLP, HPV Quadrivalent prophylactic vaccine)
- Volunteers
- 6,200 people, healthy volunteers welcome
- Sponsor
- Chinese Academy of Medical Sciences
Advanced Differentiated Thyroid Gland Carcinoma, Advanced Head and Neck Carcinoma
Testing the Combination of the Anti-cancer Drugs XL184 (Cabozantinib) and Nivolumab in Patients With Advanced Cancer and HIV
This phase I trial investigates the side effects of cabozantinib and nivolumab in treating patients with cancer that may have spread from where it first started to nearby tissue, lymph nodes, or distant parts of the body…
- Conditions
- Advanced Differentiated Thyroid Gland Carcinoma, Advanced Head and Neck Carcinoma, Advanced Hepatocellular Carcinoma, Advanced Kaposi Sarcoma
- Trial name
- NCT04514484
- Testing
- Biospecimen Collection, Cabozantinib S-malate, Computed Tomography
- Where
- 3 sites in United States
- Volunteers
- 8 people
- Sponsor
- National Cancer Institute (NCI)
Malaria, Human Immunodeficiency Virus
Reducing the Burden of Malaria in HIV-Infected Pregnant Women and Their HIV-Exposed Children (PROMOTE-BC2)
This is a double-blinded, randomized controlled trial of 200 HIV-infected pregnant women living in Tororo, Uganda, an area of high malaria transmission.
- Trial name
- NCT02282293
- Testing
- Monthly dihydroartemisinin-piperaquine (DP) + daily trimethoprim/sulfamethoxazole (TS)
- Where
- Uganda
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Vaginosis, Bacterial
Study of the Composition and Bacterial Diversity of the Vaginal Microbiota in Healthy Versus Pathological Conditions (Bacterial Vaginosis) Using a Targeted Metagenomic Approach (RNA 16s)
It aims to determine and compare the degree of vaginal bacterial alpha diversity in the absence (healthy population) or presence of bacterial vaginosis (pathological population).
- Trial name
- CEBAM (NCT04989543)
- Testing
- vaginal swabs
- Where
- France
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Larena SAS
Sexually Transmitted Diseases
A Case Control Study of Women With Multiple Sexual Partners
Both population based surveys and more focused research studies indicate that increased numbers of sexual partners and partner concurrency contribute to increased risk for acquisition of sexually transmitted infection (STI)…
- Trial name
- NCT01578915
- Where
- United States
- Volunteers
- 213 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Breast Cancer, Chronic Myeloproliferative Disorders
T Cells in Predicting Acute Graft-Versus-Host Disease in Patients Undergoing Donor Stem Cell Transplant
RATIONALE: Studying samples of blood from patients with cancer in the laboratory may help doctors predict whether patients undergoing donor stem cell transplant will develop acute graft-versus-host disease.
- Conditions
- Breast Cancer, Chronic Myeloproliferative Disorders, Gestational Trophoblastic Tumor, Leukemia
- Trial name
- NCT00651716
- Testing
- flow cytometry, laboratory biomarker analysis, Data Collection
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Vanderbilt-Ingram Cancer Center
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