Clinical trials: Genital Neoplasms, Male
Adult Central Nervous System Germ Cell Tumor, Adult Teratoma
Palifosfamide in Treating Patients With Recurrent Germ Cell Tumors
This phase II trial studies how well palifosfamide works in treating patients with recurrent germ cell tumors. Drugs used in chemotherapy, such as palifosfamide, work in different ways to stop the growth of tumor cells, either by…
- Conditions
- Adult Central Nervous System Germ Cell Tumor, Adult Teratoma, Malignant Extragonadal Germ Cell Tumor, Malignant Extragonadal Non-Seminomatous Germ Cell Tumor
- Trial name
- NCT01808534
- Testing
- palifosfamide
- Where
- 3 sites in United States
- Volunteers
- 5 people
- Sponsor
- Indiana University
Prostate Cancer, Pneumoperitoneum
Study of Carbon Dioxide Exchange Patterns During Robotic Prostatectomies
The AirSeal® System will allow for lower carbon dioxide (CO2) absorption rates than the standard Endopath System.
- Trial name
- NCT02114164
- Testing
- AirSeal System, Standard Endopath
- Where
- United States
- Volunteers
- 109 people
- Sponsor
- OhioHealth
Prostate Cancer
Evaluating the Impact of Prostate Only Versus Pelvic Radiation for N+ Prostate Cancer.
At least 40% of the patients with prostate cancer (PC) present with positive lymph nodes (N1). The optimal treatment strategy for these patients remains controversial.
- Trial name
- PROPER (NCT02745587)
- Testing
- radiotherapy
- Where
- Belgium
- Volunteers
- 69 people
- Sponsor
- University Hospital, Ghent
Prostate Cancer
Phase 2 Trial of Enzastaurin in Prostate Cancer in Participants Who Have Had Hormonal and Chemotherapy
The purpose is to see how quickly two different types of prostate cancer participants respond when taking enzastaurin. Cohort 1 - asymptomatic participants with androgen-independent prostate-specific antigen (PSA)-progressive…
- Trial name
- NCT00428714
- Testing
- enzastaurin
- Where
- 11 sites in United States
- Volunteers
- 73 people
- Sponsor
- Eli Lilly and Company
Prostate Cancer
Culturally Tailored Decision Aid for Hispanic Patients Diagnosed With Prostate Cancer
A pilot study testing the effect of an in-visit English and Spanish language decision aid for Hispanic-Latino men using best practices of cultural tailoring to be used in urology practice.
- Trial name
- NCT03157947
- Testing
- Decision Aid Tool, baseline survey, follow-up surveys
- Sponsor
- Case Comprehensive Cancer Center
Prostate Cancer
Prevalence of the c.853delT Mutation of the HOXB13 Gene in Prostate Cancer in Martinique
In Martinique, prostate cancer incidence rates are nowadays among the highest worldwide with a high incidence of early-onset and familial forms.
- Trial name
- HOXB13_Mart (NCT05231915)
- Testing
- HOXB13 c.853delT mutation
- Where
- Martinique
- Volunteers
- 465 people
- Sponsor
- University Hospital Center of Martinique
Prostate Cancer
PET Imaging Characteristics of C11-Acetate in Patients With Recurrent Prostate Carcinoma
Positron emission tomography (PET) imaging evaluation in men with recurrent prostate cancer to select patients who may benefit from directed therapy
- Trial name
- NCT01304485
- Testing
- Sodium Acetate C11
- Where
- United States
- Volunteers
- 2,000 people
- Sponsor
- Phoenix Molecular Imaging
Genitourinary Cancer, Adrenocortical Carcinoma
Nivolumab Combined With Ipilimumab for Patients With Advanced Rare Genitourinary Tumors
This research study is studying a combination of drugs as a possible treatment for rare genitourinary malignancies among four cohorts, bladder or upper tract carcinoma with variant histology, adrenocortical carcinoma, other rare…
- Conditions
- Genitourinary Cancer, Adrenocortical Carcinoma, Non-urothelial Bladder, Non-urothelial Upper Tract
- Trial name
- NCT03333616
- Testing
- Ipilimumab, Nivolumab
- Where
- 6 sites in United States
- Volunteers
- 100 people
- Sponsor
- Dana-Farber Cancer Institute
Genital Diseases, Female, Ovarian Neoplasms
Pharmacokinetic Study on the Administration of Nadroparin Dosing Serum HGF in Gynecological Patients
The purpose of this study is to determine whether HGF serum concentration might be raised in vivo by administering nadroparin given with prophylactic purpose to gynecological patients.
- Conditions
- Genital Diseases, Female, Ovarian Neoplasms, Urogenital Neoplasms
- Trial name
- NCT01523652
- Where
- Italy
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliera San Giovanni Battista
Solid Tumor
A Phase 1a/1b Study of ACTM-838 in Patients With Advanced Solid Tumors
This is a first in human (FIH) 2-part study using ACTM-838 in patients with advanced solid tumors resistant to standard of care treatment. Part 1a will evaluate dose escalation and Part 1b will evaluate dose expansion.
- Trial name
- NCT06336148
- Testing
- ACTM-838
- Where
- 5 sites in United States, Australia
- Volunteers
- 10 people
- Sponsor
- Actym Therapeutics, Inc.
Prostate Cancer, Prostate Adenocarcinoma
Pilot Trial Evaluating Stereotactic Body Radiotherapy With Integrated Boost for Clinically Localized Prostate Cancer (RAD 1203)
This study will investigate the safety, tolerability, and effectiveness of giving a higher dose to the part of the prostate which contains the cancer while giving a standard radiation dose to the entire prostate.
- Conditions
- Prostate Cancer, Prostate Adenocarcinoma, Radiation Toxicity, Sexual Dysfunction
- Trial name
- NCT01856855
- Testing
- Stereotactic Body Radiation Therapy with Integrated Boost
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- John Fiveash, MD
Prostate Cancer
High Dose Rate Prostate Brachytherapy as Salvage for Locally Recurrent Prostate Cancer Previously Treated With External Beam Radiotherapy
High dose rate (HDR) brachytherapy is a form of radiation treatment using temporary radioactive seeds. This is done by placing very tiny catheters or tubes into the prostate and then inserting temporary radioactive seeds, called…
- Trial name
- NCT00604526
- Testing
- High dose rate (HDR) brachytherapy using Iridium 192 radioactive seeds
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Prostate Cancer
The Role of Social Comparisons in Coping and Quality of Life Following a Prostate Cancer Diagnosis
Social comparisons may function as a coping strategy, but their role in coping and quality of life has not been well characterized.
- Trial name
- NCT01176526
- Where
- United States
- Volunteers
- 196 people
- Sponsor
- National Human Genome Research Institute (NHGRI)
Prostatic Neoplasms
Dosimetry, Safety and Potential Benefit of 177Lu-PSMA-617 Prior to Prostatectomy
This clinical trial will evaluate the dosimetry, efficacy and toxicity of Lu-PSMA in men with high PSMA-expressing high-risk localized or locoregional advanced prostate cancer (HRCaP) undergoing radical prostatectomy (RP) and…
- Trial name
- LuTectomy (NCT04430192)
- Testing
- 177Lu-PSMA-617
- Where
- Australia
- Volunteers
- 20 people
- Sponsor
- Peter MacCallum Cancer Centre, Australia
Preference, Patient, Pharmacist-Patient Relations
Preferences of Patients Treated With Oral Cancer Drugs and Informal Caregivers for Pharmaceutical Consultation in Hospital
To ensure the safe use of oral anticancer drugs, oncology pharmacy consultations (OPCs) have been established in France. Their goal is to provide the patient with the means to identify, prevent and limit adverse effects and to…
- Conditions
- Preference, Patient, Pharmacist-Patient Relations, Caregiver, Cancer
- Trial name
- IMPLICATION (NCT05970471)
- Where
- France
- Volunteers
- 167 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Prostate Cancer
A Study of PSMA ADC in Subjects With Metastatic Castration-resistant Prostate Cancer (mCRPC)
PSMA ADC 2301 is a Phase 2, open-label, study to assess the anti-tumor activity and tolerability of Prostate Specific Membrane Antigen Antibody Drug Conjugate (PSMA ADC) in two groups of subjects with metastatic…
- Trial name
- NCT01695044
- Testing
- PSMA ADC
- Where
- 36 sites in United States
- Volunteers
- 119 people
- Sponsor
- Progenics Pharmaceuticals, Inc.
Prostate Cancer
Measurements Of Zinc Concentration On Specimens Taken During Trans-Perineal Prostate Biopsy
The purposes of this study are to: i) confirm and improve the accuracy of the correlation between levels of Zinc in prostate tissue and the grade of prostate cancer in that tissue as determined through pathology; and ii)…
- Trial name
- NCT01915316
- Testing
- prostate biopsy
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- ProSight
Prostatic Neoplasms
The Application Value of Prostate Specific Membrane Antigen PET/CT in Biopsy Free of PSA Grey Area Prostate Cancer
The goal of this observational study is to establish an evaluation system for accurate identification of prostate cancer and clinical significant prostate cancer in patients in the PSA gray zone.
- Trial name
- NCT05958004
- Where
- China
- Volunteers
- 92 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Prostate Cancer
Feasibility and Safety Study Using Preoperative High-Dose Single-Fraction Image-Guided Radiotherapy for Men Undergoing Radical Prostatectomy at High-Risk for Extraprostatic Cancer
This study is being done to test the safety of a single high-dose of radiation therapy before radical prostatectomy (removal of the prostate).
- Trial name
- NCT01163448
- Testing
- High-Dose Single-Fraction Image-Guided Radiotherapy for Men Undergoing Radical Prostatectomy
- Where
- United States
- Sponsor
- Memorial Sloan Kettering Cancer Center
Breast Cancer, Ovarian Cancer
P-MUC1C-ALLO1 Allogeneic CAR-T Cells in the Treatment of Subjects With Advanced or Metastatic Solid Tumors
A Phase 1, open label, dose escalation and expanded cohort study of P-MUC1C-ALLO1 in adult subjects with advanced or metastatic epithelial derived solid tumors, including but not limited to the tumor types listed below.
- Conditions
- Breast Cancer, Ovarian Cancer, Non Small Cell Lung Cancer, Colorectal Cancer
- Trial name
- NCT05239143
- Testing
- P-MUC1C-ALLO1 CAR-T cells, Rimiducid
- Where
- 14 sites in United States
- Volunteers
- 180 people
- Sponsor
- Poseida Therapeutics, Inc.
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