Clinical trials: Genital Neoplasms, Male
Prostate Cancer
Prostate Cancer Active Surveillance Metformin Trial
To determine whether the use of metformin in patients with low-risk prostate cancer can delay progression to clinically significant prostate cancer.
- Trial name
- NCT01733836
- Testing
- Metformin
- Where
- Canada
- Sponsor
- University Health Network, Toronto
Breast Cancer, Prostate Cancer
[68Ga]-NeoBOMB1 Imaging in Patients With Malignancies Known to Overexpress Gastrin Releasing Peptide Receptor (GRPR)
This was a Phase II, multi-center, open label, single dose study in patients with tumor types known to overexpress Gastrin-Releasing Peptide Receptor (GRPR), including breast, prostate, colorectal, Non-Small Cell Lung Cancer…
- Conditions
- Breast Cancer, Prostate Cancer, Colorectal Cancer, Non Small Cell Lung Cancer
- Trial name
- NeoFIND (NCT03724253)
- Testing
- [68Ga]-NeoBOMB1
- Where
- 3 sites in Austria, France
- Volunteers
- 19 people
- Sponsor
- Advanced Accelerator Applications
Prostate Cancer, Urinary Incontinence
The Efficacy of Pilates in the Recovery of Post-prostatectomy Urinary Incontinence
The purpose of this study is to compare the efficacy between a Pilates exercise program and a Pelvic Floor Muscle Training (PFMT) protocol combined with anal electrical stimulation (AES) in the recovery of urinary continence (UI)…
- Trial name
- NCT02086266
- Testing
- PILATES, PFMT and AES
- Volunteers
- 54 people
- Sponsor
- Universidade Estadual de Londrina
Prostate Cancer
Radiation Therapy in Treating Patients With Stage I, Stage II, or Stage III Prostate Cancer
RATIONALE: Radiation therapy uses high-energy x-rays and other types of radiation to kill tumor cells. Giving radiation therapy in different ways may kill more tumor cells.
- Trial name
- NCT00258466
- Testing
- radiation therapy
- Sponsor
- Barbara Ann Karmanos Cancer Institute
Prostate Cancer, Obesity
Exercise, Prostate Cancer and Circulating Tumour Cells
Obesity, known to be associated with a pro-inflammatory, pro-thrombotic humoral milieu, confers a worse prognosis in prostate cancer (PrCa). Circulating tumour cells (CTCs) are identified in the blood in advanced cancer.
- Trial name
- ExPeCT (NCT02453139)
- Testing
- Exercise
- Where
- 6 sites in Ireland, United Kingdom
- Volunteers
- 67 people
- Sponsor
- University of Dublin, Trinity College
Prostate Cancer, Metastasis
Window Study of ZD4054 in Metastatic Prostate Cancer
This is a prospective study in which patients with castrate-resistant prostate cancer and bone metastases will undergo imaging, donate blood, bone marrow and urine samples, and where possible primary tumour and bone metastatic…
- Trial name
- NCT01168141
- Testing
- ZD4054
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- The Christie NHS Foundation Trust
Castration-Resistant Prostate Carcinoma, Metastatic Prostate Carcinoma
PSCA-CAR T Cells in Treating Patients With PSCA+ Metastatic Castration Resistant Prostate Cancer
This phase I trial studies side effects and best dose of PSCA-chimeric antigen receptor (CAR) T cells in treating patients with prostate stem cell antigen positive (PSCA+) castration resistant prostate cancer that has spread to…
- Conditions
- Castration-Resistant Prostate Carcinoma, Metastatic Prostate Carcinoma, Stage IV Prostate Cancer AJCC v8, Stage IVA Prostate Cancer AJCC v8
- Trial name
- NCT03873805
- Testing
- Autologous Anti-PSCA-CAR-4-1BB/TCRzeta-CD19t-expressing T-lymphocytes, Cyclophosphamide, Fludarabine
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- City of Hope Medical Center
Prostate Cancer, Prostatic Intraepithelial Neoplasia
Finasteride and Flutamide in Pre-surgical Trial in Prostate Cancer.
Pre-surgical, window-of-opportunity trials provide a suitable model to assess the activity of preventive interventions in a cost-effective manner using tissue biomarkers as surrogate endpoints.
- Trial name
- 2F (NCT06601205)
- Testing
- Flutamide, Finasteride
- Where
- Italy
- Volunteers
- 125 people
- Sponsor
- Ente Ospedaliero Ospedali Galliera
Prostate Cancer
Prevention of Micro-architectural Bone Decay in Males With Non-metastatic Prostate Cancer Receiving Androgen Deprivation Therapy (ADT)
Less than 20% of men in whom prostate cancer is diagnosed early die from it. Cardiovascular disease is the most common cause of death in men with early prostate cancer.
- Trial name
- NCT01006395
- Testing
- Zoledronic acid
- Where
- Australia
- Volunteers
- 64 people
- Sponsor
- Austin Health
Prostate Cancer, Healthy Donors
Comparative Study of Diagnostic and Prognosis Biomarkers of Prostate Cancer in Liquid Biopsy (HOPE)
Constitution of a biological collection within the framework of the establishment of a diagnostic, prognostic and active surveillance test for prostate cancer from long non-coding RNA biomarkers, in 3 cohorts of patients, with…
- Trial name
- HOPE (NCT05141383)
- Testing
- Urine sampling
- Where
- France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Institut Curie
Prostate Cancer
Vaccine Therapy in Treating Patients With Recurrent Prostate Cancer
RATIONALE: Vaccines may make the body build an immune response to kill tumor cells. PURPOSE: Phase II trial to study the effectiveness of vaccine therapy in treating patients who have recurrent prostate cancer.
- Trial name
- NCT00030602
- Testing
- PSA prostate cancer vaccine, incomplete Freund's adjuvant
- Sponsor
- University of Maryland, Baltimore
Prostate Cancer
Pretreatment Staging of High-Risk Prostate Cancer With 18F-Fluciclovine PET/MRI
There is great need for improved preoperative imaging in men with high-risk prostate cancer. Investigators propose to develop and validate an optimized simultaneous PET/MRI protocol for local, regional and whole body preoperative…
- Trial name
- NCT03264456
- Testing
- [18F] Fluciclovine PET/MRI, [18F] fluciclovine
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- University of Alabama at Birmingham
Prostate Cancer
Terbium 161 PSMA in Lutetium-177 PSMA Naive Patients
In this study it is aimed to analyze the efficacy and safety of Tb-161 PSMA I\&T in the 7.4 GBq activity in a large patient group of Lu-177 PSMA naïve mCRPC patients.
- Trial name
- TeLuNa (NCT07441837)
- Testing
- Terbium 161- PSMA I&T
- Where
- 4 sites in Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ankara University
Prostate Cancer
Model of Predicting Biochemical Recurrence After Radical Prostate Cancer Based on Pre-treatment PSMA PET / MR Image Features
The purpose of this study is to investigate the predictive value of preoperative 18F-PSMA-1007 PET/MR in the predictive effect of biological recurrence (BCR) after radical prostatectomy (RP) for localized prostate cancer (PCa).
- Trial name
- NCT06604377
- Testing
- Observe
- Where
- China
- Volunteers
- 203 people
- Sponsor
- Ruijin Hospital
Cancer of Head and Neck, Lung Cancer, Nonsmall Cell
A Multicenter Cancer Biospecimen Collection Study
This study will collect de-identified tumor samples, with correlated clinical/demographic data and tissue histology, from patients selected or scheduled for pre-treatment tumor biopsy or who have had a recent pre-treatment tumor…
- Conditions
- Cancer of Head and Neck, Lung Cancer, Nonsmall Cell, Small-cell Lung Cancer, Urothelial Carcinoma
- Trial name
- NCT04510129
- Testing
- OncoPrism™ assay
- Where
- United States
- Volunteers
- 1,650 people
- Sponsor
- Cofactor Genomics, Inc.
Testicular Cancer, Germ Cell Cancer
Everolimus for Patients With Relapsed/Refractory Germ Cell Cancer
The purpose of this study is to determine whether the drug everolimus is effective in the treatment of patients with relapsed cancer of the testis.
- Trial name
- RADIT (NCT01242631)
- Testing
- Everolimus
- Where
- 8 sites in Germany
- Volunteers
- 25 people
- Sponsor
- Hannover Medical School
Prostate Cancer
Phase I Study of Weekly Intravenous PS-341 (Bortezomib) Plus Mitoxantrone
Primary Objective: -Establish the dose-limiting toxicity (DLT) and maximum tolerated dose (MTD) of weekly mitoxantrone in combination with weekly PS-341 in patients with advanced AI-PCa.
- Trial name
- NCT00059631
- Testing
- Mitoxantrone (Novantrone), Bortezomib (PS-341)
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- M.D. Anderson Cancer Center
Metastatic Castration-resistant Prostate Cancer (CRPCa)
Impact of New Generation Hormono-therapy on Cognitive Functions in Elderly Patients Treated for a Metastatic Prostate Cancer
This study will assess the impact of the novel oral hormonal agents (abiraterone acetate or enzalutamide) among elderly metastatic prostate cancer patients.
- Trial name
- COG-PRO (NCT02907372)
- Testing
- neuropsychologic evaluation, oncogeriatric evaluation
- Where
- 6 sites in France
- Volunteers
- 163 people, healthy volunteers welcome
- Sponsor
- Centre Francois Baclesse
Prostate Cancer
Vaccine Therapy in Treating Patients With Stage D0 Prostate Cancer
RATIONALE: Vaccines made from tumor cells may help the body build an effective immune response to kill tumor cells. PURPOSE: This randomized phase II trial is studying vaccine therapy to see how well it works compared with a…
- Trial name
- NCT00514072
- Testing
- BCG vaccine, prostate cancer vaccine ONY-P1
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Kael-GemVax Co., Ltd.
Pancreatic Neoplasms, Stomach Neoplasms
Robotic vs Laparoscopic and Open Surgery for Abdominopelvic Cancers
Robotic surgery has become an increasingly common option for treating cancers in the abdomen and pelvis. However, whether robotic surgery leads to better cancer-related outcomes than laparoscopic (keyhole) surgery or open surgery…
- Conditions
- Pancreatic Neoplasms, Stomach Neoplasms, Rectal Neoplasms, Uterine Cervical Neoplasms
- Trial name
- NCT07821775
- Testing
- No Intervention: Observational Cohort
- Where
- South Korea
- Volunteers
- 32,949 people
- Sponsor
- Asan Medical Center
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.