Clinical trials: Genital Neoplasms, Male
Prostate Cancer, Prostate Cancer Metastatic
PEACE V: Salvage Treatment of OligoRecurrent Nodal Prostate Cancer Metastases
A proportion of prostate cancer (PCa) patients develop relapse following curative local treatment. Regional nodal recurrence is an emerging clinical situation since the introduction of new molecular imaging methods in the…
- Conditions
- Prostate Cancer, Prostate Cancer Metastatic, Metastatic Cancer, Oligometastatic Cancer
- Trial name
- STORM (NCT03569241)
- Testing
- whole pelvic radiotherapy, metastasis-directed treatment, salvage Lymph Node Dissection
- Where
- 29 sites in Australia, Belgium and 4 more
- Volunteers
- 196 people
- Sponsor
- University Hospital, Ghent
Prostate Cancer
Diet in Altering Disease Progression in Patients With Prostate Cancer on Active Surveillance
RATIONALE: Eating a diet high in vegetables may slow down disease progression in patients with prostate cancer. PURPOSE: This randomized clinical trial is studying how well diet works in altering disease progression in patients…
- Trial name
- NCT01238172
- Testing
- dietary education and counseling, prostate cancer foundation booklet
- Where
- 180 sites in United States
- Volunteers
- 478 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Breast Cancer, Prostate Cancer
Evaluation of a New Radiotracer (64Cu-DOTA-AE105) for Diagnosing Aggressive Cancer With Positron Emission Tomography
The primary objective of the study is to test a new radiotracer called 64Cu-DOTA-AE105 for PET imaging of uPAR (urokinase plasminogen activator receptor).
- Conditions
- Breast Cancer, Prostate Cancer, Urinary Bladder Cancer
- Trial name
- NCT02139371
- Testing
- Injection of 64Cu-DOTA-AE105
- Where
- Denmark
- Volunteers
- 10 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Prostate Cancer
Evaluating Return to Continence and Potency Following Radical Prostatectomy
The purpose of this research is to determine if using human placental membrane (also called an allograft) helps to improve recovery time for erectile function and bladder control after having robot-assisted radical prostatectomy…
- Trial name
- NCT05742334
- Testing
- Robot-Assisted Radical Prostatectomy with MLG-COMPLETE Allograft Implantation, MLG-COMPLETE Allograft Implantation
- Sponsor
- Wake Forest University Health Sciences
Bladder Cancer, Breast Cancer
OGX-011 and Docetaxel in Treating Patients With Metastatic or Locally Recurrent Solid Tumors
RATIONALE: OGX-011 may kill tumor cells by blocking some of the proteins that may cause tumor cells to grow. Drugs used in chemotherapy, such as docetaxel, work in different ways to stop the growth of tumor cells, either by…
- Conditions
- Bladder Cancer, Breast Cancer, Kidney Cancer, Lung Cancer
- Trial name
- NCT00471432
- Testing
- custirsen sodium, docetaxel, pharmacological study
- Volunteers
- 40 people
- Sponsor
- NCIC Clinical Trials Group
Prostate Cancer
Safety and Efficacy of AGN-INM176 in Prostate Patients With Rising PSA
This Phase I/II open-label trial aims to evaluate the safety and efficacy of the herbal supplement INM176 in patients with a history of prostate cancer or low-risk disease under active surveillance.
- Trial name
- NCT06600698
- Testing
- INM176
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Milton S. Hershey Medical Center
Prostate Cancer
Shear Wave Elastography of Prostate Cancer
Evaluation of significant Shear Wave Elastography Parameters for Prostate Biopsy and Prostate Cancer detection.
- Trial name
- ElaProC (NCT02425163)
- Testing
- Transrectal shear wave elastography of the prostate, Transrectal random biopsy of the prostate
- Where
- Germany
- Volunteers
- 73 people
- Sponsor
- University of Magdeburg
Breast Cancer, Colorectal Cancer
Family Quality of Life Among Families With a Member Who is a Cancer Patient
RATIONALE: Developing a questionnaire that can be used to assess the quality of life among people who have a family member with cancer may help the study of cancer in the future.
- Conditions
- Breast Cancer, Colorectal Cancer, Head and Neck Cancer, Lung Cancer
- Trial name
- NCT00544336
- Testing
- questionnaire administration, survey administration, quality-of-life assessment
- Where
- 3 sites in United States
- Volunteers
- 366 people, healthy volunteers welcome
- Sponsor
- Vanderbilt-Ingram Cancer Center
Prostate Cancer, Nerve Sparing Prostatectomy
Pilot Study of VTI Doppler Probe Use to Identify Neurovascular Bundle During Prostate Surgery
This study is designed to evaluate the use of a disposable laparoscopic Doppler probe in robotic assisted prostatectomies. The Vascular Technology, Inc.
- Trial name
- NCT01794936
- Testing
- VTI Probe
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Columbia University
Breast Cancer, Colorectal Cancer
Expectations and Priorities of Elderly Patients for a First Medical Treatment for Cancer
The main objective of study is to describe the priorities of elderly patients (70 years and over) undergoing a first medical treatment for cancer, at initiation of treatment and after 3 months of treatment.
- Conditions
- Breast Cancer, Colorectal Cancer, Kidney Cancer, Lung Cancer
- Trial name
- PRIORITY (NCT02821793)
- Testing
- Consultation, evaluation questionnaire, Geriatric consultation, evaluation questionnaire
- Where
- France
- Volunteers
- 346 people
- Sponsor
- Institut Bergonié
Prostate Cancer
Evaluation of Neuroendocrine Differentiation as a Potential Mechanism of Tumor Recurrence Following Radiotherapy
This is a pilot study to test a hypothesis that a greater increase in serum chromogranin A (CgA) after a definitive radiotherapy (RT) with or without androgen deprivation therapy (ADT) is associated with a higher risk of prostate…
- Trial name
- NCT03017794
- Where
- 3 sites in United States
- Volunteers
- 118 people
- Sponsor
- Mayo Clinic
Prostate Cancer
Digitally Captured Activity Data and PROs to Monitor Physical Function in Prostate Cancer Patients
Prospective observational research study to evaluate the role of wearable activity monitors to predict physical function decline among prostate cancer survivors receiving ADT.
- Trial name
- DigiPRO (NCT04575402)
- Testing
- Wearable Activity Monitor
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Cedars-Sinai Medical Center
Prostatic Neoplasms
The Effects of Castration on the Pharmacokinetics of Zolpidem After Single Dose Administration In Men With Prostate Cancer Undergoing Androgen Deprivation Therapy Compared to Normal Healthy Females
Background: Insomnia is associated with difficulty sleeping. The drug zolpidem is widely prescribed for insomnia. Women have reported worse effects from the drug than men.
- Trial name
- NCT03436745
- Testing
- Zolpidem, ECG
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Prostate Cancer
The Use of Zoledronic Acid in Men on Androgen Deprivation Therapy for Prostate Cancer With Preexisting Osteoporosis
This study is being conducted to evaluate the effect of an investigational drug on bone loss in men with prostate cancer who are receiving Androgen Deprivation Therapy (ADT).
- Trial name
- NCT00171639
- Testing
- zoledronic acid
- Where
- 7 sites in United States
- Volunteers
- 28 people
- Sponsor
- Novartis Pharmaceuticals
Breast Cancer, Colorectal Cancer
Study of Circulating Cancer Cells in Patients With Metastatic Breast, Ovarian, Colon, or Pancreatic Cancer
RATIONALE: Counting the number of circulating cancer cells in samples of blood from patients with metastatic cancer may help doctors find out how much the cancer has spread.
- Conditions
- Breast Cancer, Colorectal Cancer, Ovarian Cancer, Pancreatic Cancer
- Trial name
- NCT00898781
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Mayo Clinic
Malignant Testicular Germ Cell Tumor
MAGESTIC Trial: MiRNA in Detecting Active Germ Cell Tumors in Early Suspected and MetastaTIC Disease Trial
This study evaluates the accuracy of blood-based biomarker testing to predict the presence of active testicular cancer.
- Trial name
- NCT06060873
- Testing
- Clinical Stage I Disease, Clinical Stage I with relapse, CSII Disease
- Where
- 7 sites in United States, Canada
- Volunteers
- 418 people
- Sponsor
- University of Southern California
Prostate Cancer
Image-guided Navigation During Robotic Sentinel Node Removal
Image-guided navigation based on pre-operative imaging can give the surgeon more insight into the location of the sentinel nodes in relation to other anatomical structures.
- Trial name
- N21LND (NCT06091072)
- Testing
- Image-guided navigation
- Where
- Netherlands
- Volunteers
- 55 people
- Sponsor
- The Netherlands Cancer Institute
Testicular Cancer, Testicular Self-Examination
Effects of Testicular Self-Examination Training Methods on Students' Behaviors and Health Beliefs
The goal of this cluster randomized controlled trial is to evaluate and compare the effects of different testicular self-examination (TSE) training methods on university students' health beliefs and self-examination behaviors…
- Conditions
- Testicular Cancer, Testicular Self-Examination, Health Behavior, Health Knowledge, Attitudes, Practice
- Trial name
- NCT07841041
- Testing
- Educational Brochure and Audio Recording, Educational Brochure, Control Group
- Where
- Turkey (Türkiye)
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Yeditepe University
Prostate Cancer
Transrectal Ultrasound Imaging of the Prostate Gland and Neurovascular Bundles During Robot-Assisted Laparoscopic Radical Prostatectomy
Neurovascular bundle (NVB) contains capsular vessels to the prostate and cavernous nerves that provides the macroscopic landmark used during nerve-sparing radical prostatectomy.
- Trial name
- NCT00952666
- Testing
- TRUS-RALRP
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Johns Hopkins University
Prostate Cancer
Lidocaine Combined With Sufentanil for Preventing Catheter-related Bladder Discomfort
The goal of this clinical trial is to evaluate the incidence and severity of postoperative catheter-related bladder discomfort after robot-assisted radical prostatectomy.
- Trial name
- NCT05957653
- Testing
- lidocaine and sufentanil, Saline
- Volunteers
- 140 people
- Sponsor
- RenJi Hospital
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