Clinical trials: Geriatric Assessment
Cognitive Impairment, Alzheimer Disease
The SINgapore GERiatric Intervention Study to Reduce Cognitive Decline and Physical Frailty (SINGER) Study
A study in Finland found that a multidomain intervention of physical activity, nutritional guidance, cognitive training, social activities and management of vascular risk factors slowed cognitive decline in healthy older adults…
- Conditions
- Cognitive Impairment, Alzheimer Disease, Vascular Cognitive Impairment, Dementia
- Trial name
- SINGER (NCT05007353)
- Testing
- Structured Lifestyle Intervention, Self-Guided Intervention
- Where
- 3 sites in Singapore
- Volunteers
- 1,212 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Influenza
Safety, and Immunogenicity of Two Influenza Vaccines in Healthy Subjects 3 to 64 Years Old
This protocol is designed to evaluate safety, clinical tolerability and immunogenicity of the 2007 southern hemisphere formulation of a Novartis conventional influenza vaccine licensed in the EU and many other worldwide…
- Trial name
- NCT00464672
- Testing
- Influenza virus vaccine, Comparator influenza vaccine
- Where
- 2 sites in Argentina
- Volunteers
- 1,893 people, healthy volunteers welcome
- Sponsor
- Novartis
Herpes Zoster
Study to Evaluate Efficacy, Safety and Immunogenicity of GSK Biologicals' Herpes Zoster (HZ) Vaccine GSK1437173A in Adults Aged 50 Years and Older
The purpose of this observer-blind study is to evaluate the efficacy, safety and immunogenicity of GSK Biologicals' candidate Herpes Zoster (HZ) vaccine in adults aged ≥ 50 years.
- Trial name
- NCT01165177
- Testing
- Herpes Zoster Vaccine GSK1437173A
- Where
- 274 sites in United States, Australia and 16 more
- Volunteers
- 16,165 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Influenza, Seasonal Influenza
Yearly Strain Variation Study, 2009/2010
The purpose of this study is to verify the immunogenicity and tolerance of a trivalent seasonal influenza vaccine with strain composition according to World Heath Organization/European Union (WHO/EU) recommendation for the…
- Trial name
- NCT00943657
- Testing
- Preflucel [Trivalent seasonal influenza vaccine (split virus, Vero cell-derived)]
- Where
- Austria
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Alachua Government Services, Inc.
Urinary Incontinence in Old Age, Dementia
Validity and Reliability of the Turkish Form of the Knowledge Assessment Scales for Dementia and Urinary Incontinence
The primary aim of the study was to determine the Turkish version of the "Validity and Reliability of the Knowledge Assessment Scales for Dementia and Urinary Incontinence in Community Older People".
- Trial name
- NCT06758219
- Testing
- There is no intervention in the study.
- Where
- Turkey (Türkiye)
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Kirsehir Ahi Evran Universitesi
Herpes Zoster
Study on Efficacy of Attenuated Zoster Vaccine, Live
Varicella-zoster virus (VZV) is a herpesvirus that causes two distinct clinical syndromes. Primary infection is manifested as varicella (chickenpox) , whereas reactivation of latent VZV results in a localized eruption known as…
- Trial name
- NCT04334577
- Testing
- live attenuated zoster vaccine
- Where
- 2 sites in China
- Volunteers
- 25,000 people, healthy volunteers welcome
- Sponsor
- Changchun BCHT Biotechnology Co.
Physical Fitness
Equinox Personal Coaching Versus Self-Directed Exercise
The purpose of this study is to compare the Equinox Personal Coaching exercise training method to self-directed exercise training in helping subjects become more fit.
- Trial name
- NCT01778153
- Testing
- Equinox Personal Coaching
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Cerebrovascular Disease
Aerobic Dance Training in Small Vessel Disease
Introduction: Cerebral small vessel disease (SVD) is associated with age-related disabilities including dementia, depression, physical and functional impairment. Chinese are more prone to developing SVD than Caucasians.
- Trial name
- ADTSVD (NCT02730065)
- Testing
- Structured Aerobic Dance Training Group, Stretching plus education
- Where
- 2 sites in Hong Kong
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Respiratory Syncytial Virus Infections
Study to Assess the Immune Response, the Safety and the Reactogenicity of Respiratory Syncytial Virus (RSV) Prefusion Protein 3 Older Adult (OA) (RSVPreF3 OA) Investigational Vaccine When co Administered With PCV20 in Older Adults
The purpose of this study is to assess the ability of RSVPreF3 OA investigational vaccine to generate an immune response when given in combination with PCV20 and its safety in older adults, aged ≥60 years of age.
- Trial name
- NCT05879107
- Testing
- RSVPreF3 OA investigational vaccine, PCV20
- Where
- 38 sites in United States, Belgium and 2 more
- Volunteers
- 1,113 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Frailty, Physical Activity
VIVIFRAIL Program in Improving the Frailty and Physical Function in the Elderly
The global population is aging, and Taiwan has become an aging society. The aging population continues to rise. When the physical function and mental state of the elderly gradually decline, it is easy for the elderly to enter a…
- Conditions
- Frailty, Physical Activity, Cognitive Function
- Trial name
- NCT05935319
- Testing
- Vivifrail
- Where
- Taiwan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- National Taipei University of Nursing and Health Sciences
Sedentary, Deconditioning
Eccentric Cycling : a Promising Training Modality for Sedentary People
The present study aims to compare the acute and training responses of (1) eccentric high intensity interval training (EI), (2)work-matched continuous eccentric training (EC), and (3) concentric high intensity interval training…
- Conditions
- Sedentary, Deconditioning, Eccentric Exercise Training, Eccentric Cycling Exercise
- Trial name
- NCT07189975
- Testing
- High intensity eccentric cycling training, Moderate intensity eccentric cycling training, High intensity concentric cycling training
- Where
- Belgium
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Liege
Delirium, Postoperative Delirium
Stanford PIPRA Validation Study in an Elderly Orthopedic Population
The purpose of this study is to determine the accuracy of an AI-based tool in the prediction of postoperative delirium (POD), in a population at moderately high risk of developing this syndrome (i.e., elderly orthopedic…
- Conditions
- Delirium, Postoperative Delirium, Cognitive Impairment
- Trial name
- PIPRA-ORTHO (NCT06567574)
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Stanford University
Dementia, Mild Cognitive Impairment
Evaluation of the Effect of Cataract Surgery on Cognitive Function in Very Elderly Patients
The study intends to measure the evolution over time of the cognitive capacity of patients undergoing cataract surgery in relation to the opaque lens removal surgery (cataract) in a population considered to be at risk of…
- Conditions
- Dementia, Mild Cognitive Impairment, Cataract Senile, Cataract
- Trial name
- NCT04047485
- Testing
- Visual Acuity, CAM (Confusion Assesment Method), CATQUEST 9-SF
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Modena and Reggio Emilia
Influenza
Study to Evaluate the Immunogenicity and Safety of an Investigational Influenza Vaccine (H1N1) in Children
The objective of this study is to evaluate the immunogenicity and safety of GSK Biologicals' investigational vaccine GSK2340272A in children aged between 3 and 17 years.
- Trial name
- NCT00972517
- Testing
- GSK investigational vaccine GSK2340272A
- Where
- 8 sites in Germany
- Volunteers
- 245 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Interstitial Lung Disease, Idiopathic Pulmonary Fibrosis
Investigation of Pectoralis Muscle Strength in Elderly With Interstitial Lung Disease
Interstitial lung disease (ILD) is a restrictive lung disease characterized by impaired lung function, exercise limitation and skeletal muscle dysfunction.
- Conditions
- Interstitial Lung Disease, Idiopathic Pulmonary Fibrosis, Sarcoidosis, Pulmonary, Geriatric
- Trial name
- NCT04803617
- Testing
- Assessment of pulmonary function and pectoralis muscle strength
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Habibedurdu
Influenza
Safety and Immunogenicity Study of Two Doses of an Inactivated H5N1 Influenza Vaccine (Whole Virion, Vero Cell Derived)
The objectives of this Phase I/II study are to assess the safety and immunogenicity of two different dose levels of a non-adjuvanted H5N1 influenza vaccine in a healthy young adult population.
- Trial name
- NCT00517517
- Testing
- Whole virion, Vero cell-derived influenza vaccine containing either 3.75 µg or 7.5 µg H5N1 hemagglutinin (HA) antigen in a non-adjuvanted formulation
- Where
- 4 sites in Hong Kong, Singapore
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Alachua Government Services, Inc.
Covid19
Study of DS-5670a (COVID-19 Vaccine) in Japanese Healthy Adults and Elderly Subjects
This study will assess the safety, tolerability and immunogenicity of DS-5670a (COVID-19 Vaccine) and determine the recommended dose in Japanese healthy adults and elderly participants.
- Trial name
- NCT04821674
- Testing
- DS-5670a
- Where
- Japan
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- Daiichi Sankyo Co., Ltd.
Influenza
Immunogenicity and Safety Evaluation of QIS in Healthy Subjects
The purpose of this study was to evaluate the antibody response to each of the four influenza vaccine strains included in the study vaccine, as measured by hemagglutination inhibition (HAI) at 4 weeks after the last dose of the…
- Trial name
- NCT04101435
- Testing
- AdimFlu-S (QIS)
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Adimmune Corporation
Streptococcus Pneumoniae Pneumonia
PhaseⅠClinical Trial of 24-valent Pneumococcal Polysaccharide Conjugate Vaccine
In the treatment of pneumococcal diseases, the common use of penicillin-based antimicrobial agents has led to drug resistance, which has become a global challenge. Therefore, disease prevention through vaccination is essential.
- Trial name
- NCT07025876
- Testing
- low dose PCV24, high dose PCV24, PPV23
- Where
- China
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Jiangsu Province Centers for Disease Control and Prevention
Lymphoma, Malignant Solid Neoplasm
Geriatric Evaluation and Management With Survivorship Health Education for Older Survivors of Cancer, GEM-S Trial
This phase III trial compares the effect of geriatric evaluation and management with survivorship health education (GEM-S) to usual care on patient-reported physical function in older survivors of cancer.
- Trial name
- GEM-S (NCT05006482)
- Testing
- Best Practice, Comprehensive Geriatric Assessment, Educational Intervention
- Where
- 45 sites in United States
- Volunteers
- 668 people, healthy volunteers welcome
- Sponsor
- University of Rochester
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