Clinical trials: Geriatric Individuals
Rabies (Healthy Volunteers)
Immunogenicity and Safety Assessment of Rabies Vaccine (Vero Cell) for Human Use, Freeze-dried
To evaluate the immunogenicity and safety of different post-exposure prophylaxis (PEP) schedules of Sinovac rabies vaccine, in comparison with a marked rabies vaccinein china, in subjects aged 10-60 years old.
- Trial name
- NCT07357545
- Testing
- Sinovac rabies vaccine, Marketed rabies vaccine
- Where
- 2 sites in China
- Volunteers
- 2,040 people, healthy volunteers welcome
- Sponsor
- Sinovac Biotech Co., Ltd
Geriatric, Balance
Ten-meter Walking Test With Obstacle in Geriatric Individuals.
Balance and fall problems are one of the most common geriatric syndromes in the elderly. Falls are one of the leading factors causing mortality in the elderly.
- Trial name
- NCT06307769
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Ataturk University
Femoroacetabular Impingement, Hip Dysplasia
Can EOS Hip Imaging Replace CT Hip Scans?
The orientation of the femoral neck in relation to the coronal or transcondylar axis of the distal femur is known as the femoral version.
- Trial name
- EOS (NCT05921721)
- Testing
- EOS
- Volunteers
- 20 people
- Sponsor
- Sheffield Children's NHS Foundation Trust
Geriatric Individuals
Investigation of Inspiratory Muscle Strength and Cardiorespiratory Fitness in Sarcopenic Individuals
The aim of our study is to examine the effects of sarcopenia and dynapenia on inspiratory muscle strength and cardiorespiratory fitness in geriatric individuals.
- Trial name
- NCT06398704
- Testing
- Standart of care
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Hacettepe University
Mild Cognitive Impairment, Healthy Subjects With Family History for Dementia
Cognitive Stimulation in Elderly Individuals at Risk to Develop Dementia (Allena-Mente).
The Allena-Mente study is a randomized, controlled, single-blind trial assessing the efficacy of cognitive stimulation (CS) compared to an active control group, participating to sanitary education lessons (AC).
- Trial name
- Allena-Mente (NCT01793493)
- Testing
- Cognitive stimulation, Sanitary education
- Where
- Italy
- Volunteers
- 121 people
- Sponsor
- Fondazione Golgi Cenci
Impaired Glucose Tolerance
Effects of Physical Activity on the Brain in Impaired Glucose Tolerance (IGT)
The researchers will investigate whether exercise could provide positive effects on general brain functions in elderly people with impaired glucose tolerance.
- Trial name
- NCT01219231
- Testing
- Exercise
- Where
- Germany
- Volunteers
- 46 people
- Sponsor
- Charite University, Berlin, Germany
Cognition Disorders
EFFECTS OF AN OUTDOOR MAT PILATES PROGRAM ON NEUROPHYSIOLOGICAL INDICATORS OF ELDERLY INDIVIDUALS WITH MILD COGNITIVE IMPAIRMENT
Introduction: As individuals age, the quality of cognitive function becomes an increasingly important topic. Elderly people, naturally, due to the aging process, may experience a reduction in cognitive function.
- Trial name
- NCT07899372
- Testing
- Mat Pilates outdoor, Mat pilates closed environment
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- Letícia Maria Da Silva
Elderly Persons
Mandala for Anxiety, Fatigue, and Sleep
Looking at the studies on social activity programs in individuals living in nursing homes in the literature, it was seen that the studies on Mandala therapy were limited.
- Trial name
- MANDALA (NCT07145853)
- Testing
- Mandala activity
- Where
- Turkey (Türkiye)
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Marmara University
Unipolar Depression
Paroxetine and Interpersonal Psychotherapy for Maintaining Health and Well-being in Elderly Individuals With Depression
This study will evaluate the effectiveness of paroxetine versus interpersonal psychotherapy and a combination of the two in helping elderly patients with depression remain well and improve quality of their lives.
- Trial name
- NCT00178100
- Testing
- Interpersonal Psychotherapy, paroxetine
- Where
- United States
- Volunteers
- 225 people
- Sponsor
- University of Pittsburgh
Immune Senescence
Influence of Persistent CMV-infection on Immune Senescence
Recent studies indicate that persistent viral infections particularly with Cytomegalovirus (CMV) might have a negative impact on immune senescence (i.e. immunocompetence of elderly individuals).
- Trial name
- NCT00461695
- Testing
- Vaccination against TBEV (FSME Immun CC)
- Where
- Switzerland
- Volunteers
- 183 people
- Sponsor
- University of Zurich
Community Dwelling Individuals Aged 50 and Over
Identification of Frailty Predictors of Adverse Health Outcomes in Community-dwelling Individuals Aged 50 and Over
Introduction. Although ageing is a general phenomenon, a great inter individual variability on the quality of ageing can be observed.
- Trial name
- SUCCEED (NCT04603144)
- Where
- France
- Volunteers
- 3,000 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
COVID-19
Immunogenicity and Safety Study of Adjuvanted SARS-CoV-2 (SCB-2019) Vaccine in Adultsin China
The purpose of this clinical study, CLO-SCB-2019-010, is to assess the immunogenicity, reactogenicity and safety of the SCB-2019 vaccine in Chinese participants, and to show the comparability of the immune response versus…
- Trial name
- NCT04954131
- Testing
- Candidate Vaccine, SCB-2019
- Where
- 2 sites in China
- Volunteers
- 766 people, healthy volunteers welcome
- Sponsor
- Zhejiang Clover Biopharmaceuticals, Inc.
Aging, Parkinson's Disease (PD)
Impact of Force Control of Hip Abductor Muscles in Healthy Adults and Individuals With Parkinson's Disease
Both aging and Parkinson's disease (PD) negatively affect postural control and increase the risk of falls, with frontal plane balance being particularly challenging for these populations.
- Trial name
- NCT07568951
- Testing
- Age, Parkinson's disease (PD)
- Where
- 2 sites in Taiwan
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Healthy Elderly Individuals With High LDL-cholesterol or Risk of Cardiovascular Disease
Low- and Moderate-intensity Statin and Clinical Outcome of Primary Prevention in Individuals Aged >70 Years: the SCOPE-70 RCT Study
One of the most effective drug in the primary prevention of cardiovascular disease is statins. The protective effects of statin on developement of cardiovascular disease has been demonstrated in elderly individuals.
- Trial name
- NCT03770312
- Testing
- Low intensity statin, Moderate intensity statin
- Where
- South Korea
- Volunteers
- 724 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Vascular Stiffness, Vasodilation
Effects of Betalains on Cardiovascular Health and Quality of Life
The goal of this randomized, double-blind, placebo-controlled, cross-over trial is to investigate the effects of beetroot-derived betalains on cardiovascular health, sleep and quality of life in healthy middle-aged individuals.
- Conditions
- Vascular Stiffness, Vasodilation, Sleep, Quality of Life
- Trial name
- NCT06117007
- Testing
- Betalains
- Where
- United Kingdom
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- King's College London
Non-sarcopenic Subjects, Possible Sarcopenia
Research on the Possible Relationship Between Sarcopenia and Oral Muscle Function
This study will focus on community-dwelling elderly individuals and will follow the community screening process recommended by AWGS.
- Conditions
- Non-sarcopenic Subjects, Possible Sarcopenia, Sarcopenia (With Low ASM by BIM)
- Trial name
- GSOM (NCT07658612)
- Testing
- Non interventional study
- Where
- Taiwan
- Volunteers
- 251 people, healthy volunteers welcome
- Sponsor
- Chang Gung University of Science and Technology
Respiratory Syncytial Virus Infection
SPECIAL INVESTIGATION FOR ABRYSVO IN INDIVIDUALS AGED 60 YEARS OR OLDER
This post-marketing study is a multicenter cohort study in individuals aged 60 years or older vaccinated with Abrysvo (RSV vaccine)designed to confirm the safety in individuals aged 60 years or older under actual clinical…
- Trial name
- NCT06546800
- Testing
- RSVpreF vaccine
- Where
- Japan
- Volunteers
- 1,100 people, healthy volunteers welcome
- Sponsor
- Pfizer
Sedentary Behavior
Effect of Cocoa Supplementation and Aerobic Exercise on Pressure Parameters
This study evaluates the cocoa supplementation and aerobic exercise on central pressure and arterial stiffness parameters in physically inactive middle-aged individuals. 500mg capsules will be offered to all patients.
- Trial name
- NCT04732754
- Testing
- Aerobic exercise + Theobroma cocoa (AETC), Control Group (CG), Aerobic Exercise (AE)
- Where
- Brazil
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Instituto de Cardiologia do Rio Grande do Sul
Mild Cognitive Impairment (MCI)
The Effects of Single Baduanjin and Elastic Band Exercises on VSWM in Elderly Individuals With MCI
Previous studies have confirmed that both acute (single) and long-term various exercise interventions can significantly improve the cognitive function of individuals with MCI.
- Trial name
- NCT07656480
- Testing
- baduanjin exercise, elastic band exercises
- Volunteers
- 60 people
- Sponsor
- qiu chen
Happiness, Life Satisfaction
The Effect of Recreational Games on Happiness, Life Satisfaction, Loneliness, and Somatisation in Elderly Individuals
As per the United Nations population projections, the percentage of individuals aged 65 and older in the global population is expected to increase from 10% in 2022 to 16% by the year 2050.
- Conditions
- Happiness, Life Satisfaction, Loneliness, Somatization
- Trial name
- NCT06505070
- Testing
- Recreational Games
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Duzce University