Clinical trials: Gingiva Atrophy
Gingival Recession
Effect of Botulinum Toxin a Injection in Treatment of Recession RT1 and RT2
The goal of this study type: clinical trial] is to learn the effect of Botulinum Toxin _A injection in treatment of RT1andRT2 Gingival recession in lower anterior teeth . Primary outcome is keratinzed tissue width.
- Trial name
- NCT06842290
- Testing
- Botulinum toxin-A injection, Coronally advanced flap
- Volunteers
- 28 people
- Sponsor
- Cairo University
Suture, Complication, Gingival Recession
The Effects of Palatal Pre-sutures in Connective Tıssue Graft Surgery
Connective tissue graft operation is one of the most frequently performed surgical procedures to increase the width of the attached gingiva and to treat gingival recessions.
- Conditions
- Suture, Complication, Gingival Recession, Bleeding Hemorrhage
- Trial name
- NCT05395923
- Testing
- Suture, No Suture CTG -Control
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Biruni University
Periodontitis, Gingivitis and Periodontal Diseases
Salivary Free Amino Acid Profiles in Periodontitis: Associations With Clinical Parameters and Dynamic Responses to Non Surgical Therapy
# Brief Summary (Word count: 198) This combined observational and interventional study investigates salivary amino acid profiles and their connections to periodontal conditions, as well as how these substances change after…
- Conditions
- Periodontitis, Gingivitis and Periodontal Diseases, Periodontal Debridement, Periodontal Attachment Loss
- Trial name
- FAA-CP-SRP (NCT07669233)
- Testing
- Non-surgical periodontal therapy
- Where
- China
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Zhang, Yuwei
Gingival Recession
Tunnel With and Without Intramucosal Vertical Incisions
Thirty patients will be treated: 15 with a coronally positioned tunnel technique plus intramucosal verticals with AlloDerm® (test treatment) and 15 with a coronally positioned tunnel technique alone with AlloDerm® (control…
- Trial name
- NCT02486991
- Testing
- Tunnel + AlloDerm®, Tunnel + AlloDerm® + Verticals
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Louisville
Gingival Recession, Localized, Gingival Recession, Plastic Surgery
Comparing CAF and TCAF With Soft Tissue Grafting for Treating Multiple Recessions in the Premandibula.
Multiple techniques can be used for recession coverage. The most common techniques are : tunnel technique (T), coronally advanced flap (CAF) or a combination of both (TCAF).
- Conditions
- Gingival Recession, Localized, Gingival Recession, Plastic Surgery, Gingival Recessions, Gingival Recession, Mucogingival Surgery
- Trial name
- NCT06940050
- Testing
- Coronally advanced flap with a connective tissue graft, Tunneled coronally advanced flap with a connective tissue graft
- Where
- Belgium
- Volunteers
- 34 people
- Sponsor
- University Hospital, Ghent
Gingival Recession
Advanced Platelet-Rich Fibrin and Coronally Advanced Flap for Gingival Recession Treatment
The goal of this clinical trial is to learn if adding a natural healing material works better to treat receding gums in adults. Receding gums is a condition where the gum tissue pulls back and exposes the tooth root.
- Trial name
- NCT07624591
- Testing
- Coronally Advanced Flap (CAF) combined with Advanced Platelet-Rich Fibrin (A-PRF), Coronally Advanced Flap (CAF) alone
- Where
- Vietnam
- Volunteers
- 11 people
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Gingival Recession Localized Moderate
Comparing Tunnel Technique and CAF With CTG in Mandibular Gingival Recession Treatment
The goal of this clinical trial is to evaluate the effectiveness of two different surgical techniques, the Coronally Advanced Flap (CAF) and the Tunnel Technique (TT) with Connective Tissue Grafts (CTG), in treating mandibular…
- Trial name
- NCT06135662
- Testing
- CAF + CTG, Tunnel Technique + CTG
- Where
- Spain
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Gingival Recession
Clinical Evaluation of the Modified Laterally Stretched Technique (RT2) Gingival Recession vs Tunneling With CT Grafting
Regression analysis in a recent systematic review showed significantly greater mRC and CRC values when modifications are done to the TUN procedure to achieve more coronal advancement of the flap, coronal advancement also helps in…
- Trial name
- NCT06044870
- Testing
- Modified laterally stretched technique with a connective tissue graft.
- Where
- Egypt
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Cairo University
Palatal Wound
Effect of Low-level Laser Therapy on Palatal Wound Healing
The aim of the present study was to evaluate the influence of LLLT on the recovery of the palatine donor site wounds after harvest connective tissue graft.
- Trial name
- LLLT (NCT02239042)
- Testing
- LLLT
- Where
- Brazil
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- UPECLIN HC FM Botucatu Unesp
Gingival Recession
Treatment of Gingival Recession Defects Using Platelet-Rich Fibrin With an Allogenic Dermal Matrix
The study aims to test the non-inferiority of an Allogenic Dermal Matrix with Platelet-Rich Fibrin for treatment of gingival recessions in comparison to the Connective Tissue Graft.
- Trial name
- NCT05819515
- Testing
- Tunneled coronally advanced flap
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Gingival Recession, Periodontal Plastic Surgery
Volumetric Changes After Free Gingival Graft: Tuberosity vs Palatal Donor Site (VolFGG-TP)
This randomized controlled clinical trial evaluated volumetric changes at recipient and donor sites following free gingival graft (FGG) surgery, comparing two different palatal donor regions.
- Trial name
- NCT07554625
- Testing
- Free Gingival Graft from Anterior Palatal Donor Site, Free Gingival Graft from Posterior Palatal / Tuberosity Donor Site
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hooman Hashemzadeh
Gingival Recessions
Evaluation of the Clinical Efficacy of De-Epithelialized Free Gingival Graft in the Treatment of Gingival Recessions
The aim of this study is to evaluate the clinical effectiveness of three techniques used in combination with the tunnel method for the treatment of multiple gingival recessions: subepithelial connective tissue graft (SCTG Group)…
- Trial name
- NCT07100808
- Testing
- Using the tunnel technique in the treatment of gingival recession
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Yuzuncu Yil University
Gingival Recession
A Comparision of Collagen Matrix and Connective Tissue Graft With Modified Coronally Advanced Tunnel for Root Coverage
Recently porcine derived bioresorbable collagen matrices have shown predictable outcomes for augmenting keratinzed gingiva , improved wound healing, recession coverage in localized gingival recessions and multiple recession…
- Trial name
- NCT02876562
- Testing
- root coverage with collagen matrix
- Where
- India
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Krishnadevaraya College of Dental Sciences & Hospital
Gingival Recession
Connective Tissue Graft From Tuberosity Area and L-PRF Associated With Coronally Advanced Flap for Root Coverage
The aim of the present randomized controlled clinical study is to compare the efficacy of subepithelial connective tissue graft harvested from the maxillary retromolar tubeosity area and L-PRF membranes in the treatment of RT1…
- Trial name
- NCT05783258
- Testing
- Periodontal surgery with CAF+tSCTG, Periodontal surgery with CAF+L-PRF
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- G. d'Annunzio University
Gingival Recession, Inadequately Attached Gingiva
Efficacy of Collagen Sponge on Palatal Wound Healing
The aim of this study is to compare the efficacy of collagen sponge and gelatin sponge on the palatal wound healing and postoperative pain following gingival graft harvesting.
- Trial name
- NCT05287763
- Testing
- Palatal soft tissue graft harvesting
- Where
- China
- Volunteers
- 32 people
- Sponsor
- The Dental Hospital of Zhejiang University School of Medicine
Gingival Recession
TECHNIQUES USED IN EVALUATION OF GINGIVAL PHENOTYPE
This study evaluates the 4 different techniques used in clinical measurement of gingival phenotype. 1) Tranclusency of UNC-15 Periodontal Probe, 2) Transgingival probing with Endodontic file (#20), 3)Transgingival Probing with…
- Trial name
- NCT05478148
- Testing
- Gingival thickness
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Gingival Recession, Localized
Effect of Vestibular Depth on Predictability of Miller Class III/ RT2 Gingival Recession Coverage
Aim of this study is to assess the influence of vestibular depth on root coverage in Miller class III/ Cairo RT2 gingival recession when treated with minimally invasive technique using connective tissue graft.
- Trial name
- NCT06000228
- Testing
- Recession coverage with CTG using minimally invasive access technique in shallow vestibule, Recession coverage with CTG using minimally invasive access technique in deep vestibule
- Where
- India
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Gingival Recession, Gingival Diseases
Biofiller and Gingival Phenotype Thickening
The periodontal phenotype is defined as the combination of the gingival phenotype and the thickness of the buccal bone plate (bone morphotype).
- Conditions
- Gingival Recession, Gingival Diseases, Gingival Inflammation
- Trial name
- NCT07104019
- Testing
- Biofiller Injection, connective tissue graft
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Inonu University
Gingival Recession
Safety and Efficacy of Gintuit(TM)for Oral Soft Tissue Regeneration
The purpose of this study is to evaluate Gintuit as a safe and effective alternative to palatal tissue in the treatment of subjects (with recession-type defects) who have an insufficient zone of attached gingiva associated with…
- Trial name
- NCT00587834
- Testing
- Gintuit, Autologous palatal tissue
- Where
- 4 sites in United States
- Volunteers
- 96 people
- Sponsor
- Organogenesis
Gingival Recession
Root Biomodification With Citric Acid and Tetracycline Improves the Outcomes of Root Coverage
The aim of this study is to investigate the effects of the application of a citric acid + tetracycline gel solution during 90 or 180 seconds compared to no conditioning in the outcomes of treatment of Miller's class I or II…
- Trial name
- NCT02259543
- Testing
- Root conditioning with citric acid+tetracycline solution
- Where
- Brazil
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo