Clinical trials: Gingiva Disorder
Periodontitis, Periimplantitis
PPAR, RXR, and VDR Expressions in Peri-implantitis
ABSTRACT Objective: Periodontitis and peri-implantitis are the irreversible destructive diseases of the periodontal and peri-implant tissues.
- Trial name
- NCT04020146
- Testing
- Gingival biopsies
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Periodontitis
Photodynamic Therapy Plus Root Debridement in Gum Disease Treatment V2
Gum disease is a common disease, which affects 45% of the UK adult dentate population. It is caused by bacteria in dental plaque, which produces inflammation and a deepening of the natural crevice between the gum and the tooth…
- Trial name
- PDTV2 (NCT03270254)
- Testing
- light activated dye photodynamic therapy (PDT)
- Where
- United Kingdom
- Volunteers
- 31 people
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Dental Plaque
The Effect of Air Polishing on the Tooth Surface
The use of air-polishing device that operates by directing a fine slurry of pressurized air, water, and abrasive particles has become widespread in dentistry for polishing.
- Trial name
- NCT04853745
- Testing
- AIR-FLOW® Master Piezon
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Kocaeli University
Gingival Overgrowth
Comparison Between Laser, Synthetic Gel and Herbal Gel as Topical Agents After Gum Surgery
This study would be conducted to assess the effectiveness of low-level laser therapy, hyaluronic acid gel and herbal gel as adjunctive aids in the healing of gingivectomy wounds.
- Trial name
- CLSHGTAGS (NCT03569683)
- Testing
- External bevel gingivectomy, Diode laser Biostimulation, Hyaluronic acid (Gengigel) topical application.
- Where
- India
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Panineeya Mahavidyalaya Institute of Dental Sciences & Research Centre
Bladder Cancer, Cervical Cancer
Varenicline or Nicotine Patch and Nicotine Gum in Helping Smokers in a Methadone Treatment Program Stop Smoking
RATIONALE: Varenicline, the nicotine patch, and nicotine gum help people stop smoking. It is not yet known whether varenicline is more effective than the nicotine patch given together with nicotine gum in helping smokers quit…
- Conditions
- Bladder Cancer, Cervical Cancer, Esophageal Cancer, Gastric Cancer
- Trial name
- NCT00790569
- Testing
- nicotine, varenicline
- Where
- United States
- Volunteers
- 315 people
- Sponsor
- Butler Hospital
Periodontal Disease, Chronic Neck Pain
Association Between Periodontal Disease and Chronic Neck Pain
This study investigates whether there is an association between periodontal disease (gum disease) and chronic neck pain and related functional disability.
- Trial name
- NCT07711431
- Where
- Turkey (Türkiye)
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- Nigde Omer Halisdemir University
Periodontitis, Gingivitis
Diagnostic Accuracy of Rapid Non-clinical Screening Tests for Early Detection of Periodontitis
Gum disease is the 6th most prevalent disease of mankind. It is a non-communicable non-resolving inflammation; if untreated it leads to tooth loss and inability to chew properly.
- Trial name
- NCT03928080
- Testing
- Bleeding on brushing
- Where
- China
- Volunteers
- 408 people, healthy volunteers welcome
- Sponsor
- The European Research Group on Periodontology (ERGOPerio)
Autism Disorder, Autism Spectrum Disorder (ASD
Effectiveness of Interactive Techniques on Oral Hygiene Skills in a Group of Autistic Egyptian Children
The present study will be performed to evaluate the effectiveness of peer modeling and audiovisual peer modeling video on toothbrushing skills in comparison to the visual pedagogical method at home.
- Conditions
- Autism Disorder, Autism Spectrum Disorder (ASD, Autism, Plaque Reduction
- Trial name
- Autism ASD (NCT07859696)
- Testing
- Peer model, Pre-recorded video of peer modeling, Pedagogical method
- Volunteers
- 90 people
- Sponsor
- Faculty of Dental Medicine for Girls
Gingivitis
The Efficacy of Full Mouth Erythritol Powder Air-Polishing Therapy (FM-EPAPT) Versus Traditional Ultrasonic Debridment (UD): a Randomized Controlled Study.
Traditional methods for plaque and calculus removal involve the use of mechanical and/or manual instruments, followed by surface polishing with rubber cups and low abrasive pastes.
- Trial name
- ERICO (NCT04455269)
- Testing
- AIRFLOW® with PLUS® powder and PIEZON® scaler, PIEZON® scaler and rubber cup with abrasive paste
- Where
- Italy
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia
Dental Plaque, Gingivitis
A Study to Investigate the Efficacy of an Experimental Dentifrice Containing Stannous Fluoride in Improving Gingival Health
The aim of this study will be to evaluate the ability of using an experimental dentifrice containing 0.454 percent (%) weight for weight (w/w) Stannous Fluoride (SnF2) to reduce gingivitis and plaque accumulation, compared with a…
- Trial name
- NCT07704905
- Testing
- Test Dentifrice, Reference Dentifrice (Colgate Cavity Protection Dentifrice)
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- HALEON
Gingival Recession
Acellular Dermal Matrix Graft In Root Coverage of Gingival Recessions With Previously Restored Cervical Lesions
Patients with high standards of oral hygiene frequently search for buccal gingival recession (GR) treatment due to cervical wear, root sensitivity and compromising aesthetics.
- Trial name
- NCT03615092
- Testing
- Root coverage with extended flap technique and acelular dermal matrix
- Where
- Brazil
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Periodontitis
Periodontitis on Gingival Crevicular Fluid Metobolomics
This cross-sectional observational study will compare the gingival crevicular fluid metabolomic profile of 30 adults with periodontitis and 30 periodontally healthy adults.
- Trial name
- NCT07739732
- Testing
- Periodontal probing depth
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Catania
Gingivitis
A Phase 3 Clinical Study Investigating the Gingivitis Efficacy of a Test Dentifrice Containing Stannous Fluoride
The purpose of this study is to evaluate and compare the gingival health of a test dentifrice (0.454% weight by weight [w/w] stannous fluoride) to a negative control dentifrice by comparing modified gingival index, bleeding index…
- Trial name
- NCT04123665
- Testing
- Stannous fluoride, Sodium monofluorophosphate
- Where
- United States
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Periodontal Disease, Gingival Disease
Evaluation of Gingival Health Parameters in Hybrid CAD / CAM Crowns Produced After Different Retraction Processes
Clinically, the gingival retraction dentistry itself has found wide uses. It has achieved the use of subgingival and gingival crowns in fixed prostheses, cervical abrasion in restorative dentistry, management of root caries and…
- Trial name
- NCT03816930
- Testing
- mechanical cord usage
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Yuzuncu Yil University
Periodontal Disease, Periodontal Diseases
Assessment of Pentraxin Levels in the Gingival Fluid of Abutment Teeth in the Context of the Use of Fixed Dentures
The use of fixed dentures in prosthetic treatment requires a thorough analysis of clinical factors such as: the condition of the abutments subject to grinding procedures, the degree of their loosening, the extent of missing…
- Conditions
- Periodontal Disease, Periodontal Diseases, Prosthodontics
- Trial name
- NCT07271563
- Testing
- Diagnostic Pentraxine test
- Where
- Poland
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Jagiellonian University
Gingival Recession
Inverted T-shape Free Gingival Graft for Treatment of RT2 / RT3 Gingival Recession Defects
The aim of this study is to compare the use of T-inverted shape Free Gingival Graft with Free Gingival Graft for improving the clinical attachment, gain partial root coverage, and improve Keratinized tissue width in recession…
- Trial name
- NCT06615687
- Testing
- Inverted T shape Free Gingival Graft, Free Gingival Graft
- Where
- Egypt
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Cairo University
Infra-bony Periodontal Defect
Effect of Gingival Mesenchymal Stem Cell-Derived Small Extracellular Vesicles in Management of Infra-bony Periodontal Defect
The goal of the study to evaluate whether the adjunctive use of gingival mesenchymal stem cell-derived extracellular vesicles (GMSC-derived EVs) combined with β-tricalcium phosphate (β-TCP) and a collagen membrane results in…
- Trial name
- NCT07867067
- Testing
- Gingival mesenchymal stem cell derived small extracellular vesicles, β-calcium triphosphate (β-TCP) + collagen membrane
- Where
- Egypt
- Volunteers
- 22 people
- Sponsor
- Ain Shams University
Periodontitis, Periodontitis Stage II
Surfactant Protein D Levels in GCF Before and After MINST in Periodontitis
This study will evaluate changes in Surfactant Protein D (SP-D) levels in gingival crevicular fluid (GCF) of patients with periodontitis before and after minimally invasive non-surgical periodontal therapy (MINST).
- Conditions
- Periodontitis, Periodontitis Stage II, Periodontitis Stage III
- Trial name
- NCT07599657
- Testing
- Minimally Invasive Non-Surgical Periodontal Therapy
- Where
- Egypt
- Volunteers
- 18 people
- Sponsor
- Cairo University
Idiopathic Thrombocytopenic Purpura
Study of a New Medication for Childhood Chronic Immune Thrombocytopenia (ITP), a Blood Disorder of Low Platelet Counts That Can Lead to Bruising Easily, Bleeding Gums, and/or Bleeding Inside the Body.
The purpose of this study is to investigate the efficacy, safety and tolerability of eltrombopag in children with previously treated chronic immune thrombocytopenia who are between 1 and 17 years of age. This is a 2 part study.
- Trial name
- PETIT2 (NCT01520909)
- Testing
- Eltrombopag
- Where
- 51 sites in United States, Argentina and 11 more
- Volunteers
- 92 people
- Sponsor
- GlaxoSmithKline
Gingival Recession
Guided Creeping Technique (GCT) in Treating Gingival Recession
A novel minimally invasive guided creeping technique (GCT) is suggested to treat gingival recessions.
- Trial name
- NCT05101642
- Testing
- Guided Creeping Technique (GCT)
- Where
- Egypt
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- October 6 University
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