Clinical trials: Gingiva Disorder
Gingival Recession
Coronally Advanced Flap With or Without Porcine Collagen Matrix for Root Coverage
The purpose of this study is to compare the clinical outcomes after coronally advanced flap technique (CAF) associated or not to a porcine collagen matrix graft (CM) in the treatment of single gingival recessions.
- Trial name
- NCT02242500
- Testing
- Coronally Advanced Flap, Mucograft
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- Enilson Antonio Sallum
Gingival Recession, Mucogingival Surgery
Effects of Low-Level Laser Therapy and Hyaluronic Acid After Free Gingival Graft
The goal of this randomized clinical trial was to learn whether low-level laser therapy or hyaluronic acid application improves healing after free gingival graft surgery in adults with insufficient keratinized gingival tissue in…
- Trial name
- NCT07751211
- Testing
- Topical Hyaluronic Acid Gel, Low-Level Laser Therapy, Free Gingival Graft Surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Altinbas University
Missing Teeth
Assessment of Hard and Soft Tissue Changes Following XCM Versus FGG Simultaneous With Delayed Dental Implant Placement
Teeth loss are usually associated with alterations of extraction sockets result in obviously absorbed alveolar ridges and are often accompanied with soft tissue atrophy such as narrow keratinized tissue and a shallow vestibule.
- Trial name
- NCT07080177
- Testing
- Free gingival graft simultaneous with delayed implant placement, Xenogeneic collagen matrix simultaneous with delayed implant placement
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cairo University
Gingivitis, Mouth Diseases
Clinical Effects of Tooth Powder on Gingivitis
Dental plaque, known as dental biofilm, is implicated as the primary etiological agent responsible for oral inflammatory diseases.
- Trial name
- Toothpowder (NCT01902095)
- Testing
- Tooth powder, Tooth paste (control)
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- Sheikh Zayed Federal Postgraduate Medical Institute
Acne Vulgaris, Gingivitis and Periodontal Diseases
Retinoic Acid Therapy and Regulation of Salivary and Serum IL-1β, IL-8 and MCP-1 Levels
This prospective cohort study analysed the effects of systemic retinoic acid use on periodontal status, salivary flow rate (SFR), and salivary and serum levels of interleukin (IL)-1β, IL-8 and monocyte chemoattractant protein…
- Conditions
- Acne Vulgaris, Gingivitis and Periodontal Diseases, Saliva Collection, Inflammation Biomarkers
- Trial name
- NCT06879795
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Medipol University
Laryngeal Mask, Throat Pain
The Effect of Preoperative Chewing Gum on Anxiety and Sore Throat in Patients With Laryngeal Mask Airway
This study was planned to investigate the effect of chewing gum in the preoperative period on patients' sore throat and anxiety levels.
- Conditions
- Laryngeal Mask, Throat Pain, Anxiety
- Trial name
- NCT06168981
- Testing
- Chewing Gum
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Ankara Medipol University
Severe Neutropenia, Thrombocytopenia
Effect of Supragingival Irrigators Containing Chlorhexidine on Oral Health in Blood Dyscrasia
in this study , effectiveness of supragingival irrigators containing chlorhexidine is compared with routine oral health measures in patients with blood dyscrasia whom can not use effective oral health measures(e.g brushing ) due…
- Conditions
- Severe Neutropenia, Thrombocytopenia, Chemotherapy, Blood Dyscrasia Patients
- Trial name
- NCT01974401
- Testing
- supragingival irrigators containing chlorhexidine
- Where
- Iran
- Volunteers
- 20 people
- Sponsor
- Mashhad University of Medical Sciences
Bacteremia, Infective Endocarditis
Reducing Risk for Infective Endocarditis
This clinical trial is studying if bacteria found in a participant's bloodstream after brushing their teeth can be prevented with a dental cleaning and more education on how to best brush and care for their teeth.
- Trial name
- PIE-B (NCT05721781)
- Testing
- Oral Hygiene instruction, Dental Cleaning
- Where
- 6 sites in United States
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Cross-linked Hyaluronic Acid
Treatment of Buccal Ginvigal Recessions With the Tunnel Technique in Conjunction With Cross-linked Hyaluronic Acid and Subepithelial Connective Tissue Graft. A Randomized Clinical Trial
To evaluate the outcomes of buccal gengival recession type 1 (RT1) treated with the tunnel technique in conjunction with a cross-linked hyaluronic acid and subepithelial palatal connective tissue grafts.
- Trial name
- NCT05436002
- Testing
- With Cross-linked Hyaluronic Acid
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Lisbon
Gingival Retraction, Gingival Recession
The Impact of Retraction Cords on the Gingival Margin Level.
The purpose of this study is to examine the relationship between placing specific retraction cord for different periods of time and the post-operative gingival margin level in humans.
- Conditions
- Gingival Retraction, Gingival Recession, Periodontal Health
- Trial name
- NCT05949073
- Testing
- Non-impregnated retraction cords/ less than 10 minutes, Non-impregnated retraction cords/ more than 10 minutes, impregnated gingival retraction cord - less than 10 minutes
- Where
- Jordan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Jordan
Periodontal Diseases
Tumor Necrosis Factor-alpha and Interleukin-18 Levels in Children With Gingivitis and Type 1 Diabetes Mellitus
This study aimed to evaluate the levels of interleukin 18 and tumor necrosis factor-alpha (TNF-α) in gingival crevicular fluid (GCF) of children with type 1 diabetes mellitus and gingivitis.
- Trial name
- NCT03910205
- Testing
- ELISA
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Gingival Enlargement
Evaluation of Healing Process After Laser Asissted Gingivectomy Techniques
Objective: The aim of this study was to evaluate and determine clinical and biochemical comparison of 3 different methods including Er:YAG laser, diod laser, and conventional techniques.
- Trial name
- NCT04304391
- Testing
- Resective Gingival Surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Periodontal Disease
Characterizing Gingival and Periodontal Ligament Fibroblasts Reaction to Infection With the Bacteria Porphyromonas Gingivalis
Porphyromonas gingivalis is one of the major bacteria involved in the formation and progression of chronic periodontitis. Pathogens invading the gingiva face the host's innate immune system at first and later on the acquired…
- Trial name
- NCT01599091
- Testing
- Specimens collection
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Hadassah Medical Organization
Gingivitis
Stingless Bee Honey Mouth Rinse on Gingivitis
The currently used chemical mouth rinse, chlorhexidine, was prescribed widely among dental practitioners for its ability to kill bacteria.
- Trial name
- NCT07461155
- Testing
- mouth rinse, scaling, oral hygiene education and instruction
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ministry of Higher Education, Malaysia
Gingivitis, Gingival Bleeding
Clinical Assessment of the Safety and Efficacy of Flaus Electric Flosser on Plaque and Gingivitis Compared to a Manual Toothbrush
The purpose of this study to evaluate the safety and efficacy of an electric flosser (interproximal cleaning aid), when used with a manual toothbrush and fluoride toothpaste, on gingivitis reduction and dental plaque removal.
- Conditions
- Gingivitis, Gingival Bleeding, Dental Plaque
- Trial name
- NCT07805148
- Testing
- Device: Electric Flosser, Manual toothbrush
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Flaus, Inc
Gingival Diseases, Traumatic Injury
Injectable Platelet Rich Fibrin With Collagen Matrix in Treatment of Multiple Gingival Recession.
This study is proposing the use of i-PRF clot as a scaffold for the XCM in order to obtain a novel biomaterial, incorporating active growth factors and collagen matrix in a single framework, based on the potential effect of i-PRF…
- Trial name
- NCT05389059
- Testing
- CAF+CM, I-PRF
- Where
- Iraq
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Gingival Recessions
m-VISTA Technique vs. CAF in the Treatment of Class III Multiple Recessions
The main objective is to assess whether the percentage of root coverage (%RC) achieved in the treatment of multiples class III recessions using the technique we have called modified vestibular incision subperiosteal tunnel access…
- Trial name
- NCT03258996
- Testing
- Modified vestibular incision subperiosteal tunnel access, Coronally advanced flap
- Where
- Spain
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Aitziber Fernandez Jimenez
White Spot Lesions
PATIENT SATISFACTION AND MASKING OF WHITE SPOT LESIONS AFTER HOME WHITENING WITH 10% CARBAMIDE PEROXIDE
The clinical trial aims to evaluate patient satisfaction and the efficacy of home whitening with 10% carbamide peroxide in masking white spot lesions, as well as the presence of sensitivity and gingival irritation.
- Trial name
- NCT07247760
- Testing
- Whitening treatment with 10% carbamide peroxide on teeth with white spot lesions
- Where
- Spain
- Volunteers
- 67 people
- Sponsor
- Universidad Rey Juan Carlos
Periodontal Diseases, Periodontitis
Evaluation Of The Efficacy Of Subgingival Application Of Lovastatin Gel As An Adjunct To Non-Surgical Treatment Of Periodontitis In Generally Healthy Smokers And Non-Smokers Patients in Central Europe.
The aim of the study is to evaluate how a gel (1.2% lovastatin) applied under the gum improves the results of classic periodontal treatment (SRP-scaling, root planing).
- Conditions
- Periodontal Diseases, Periodontitis, Periodontal Disease, Smokers
- Trial name
- RCT (NCT07282756)
- Testing
- Subgingival application of 1.2% lovastatin
- Where
- Poland
- Volunteers
- 44 people
- Sponsor
- Medical University of Silesia
Dental Caries, Tooth Demineralization
Effectiveness of Two Health Education Interventions in the Prevention of Caries and Gingivitis in Orthodontic Patients
Dental caries and gingivitis are classified by the World Health Organization (WHO) as an important public health problem due to their high prevalence and incidence worldwide despite the development of public policies to combat…
- Conditions
- Dental Caries, Tooth Demineralization, Gingivitis
- Trial name
- NCT05979805
- Testing
- Conventional Educational interventions, Motivational intervention
- Where
- Colombia
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Universidad Nacional de Colombia
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