Clinical trials: Gingival Condition
Gingivitis
Powered Toothbrush Versus Manual Toothbrush on Plaque and Gingivitis After a Six-Week Period of Home Use
The goal of this clinical trial is to learn if powered toothbrushing is more effective than manual toothbrushing in removing dental plaque. It will also learn about the safety of power toothbrushing.
- Trial name
- NCT07691814
- Testing
- power toothbrush, manual toothbrush
- Where
- United States
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Philips Clinical & Medical Affairs Global
Gingival Graft, Recession, Gingival
i-PRF-Based Bioactive Matrix vs. Connective Tissue Graft in the Treatment of Gingival Recessions
This study aims to evaluate the efficacy of a novel bioactive matrix, consisting of an equine collagen core soaked in i-PRF and wrapped in L-PRF, used in combination with a coronally advanced flap as an alternative to the…
- Conditions
- Gingival Graft, Recession, Gingival, Platelet Rich Fibrin
- Trial name
- NCT07918326
- Testing
- Coronally advanced flap and i-PRF based bioactive matrix, Coronally advanced flap and subepithelial connective tissue graft
- Where
- Italy
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- G. d'Annunzio University
White Spot Lesion of Tooth, Gingival Inflammation
EFFECTIVENESS of WATER FLOSS in PLAQUE REMOVAL and PREVENTION of WHITE SPOT LESIONS in ORTHODONTIC PATIENTS: a RANDOMISED CONTROLLED CLINICAL TRIAL
This clinical trial aims to learn if water floss is as efficient as other interdental cleaning tools and can prevent plaque accumulation and white spot lesions (WSLs) in orthodontic patients.
- Conditions
- White Spot Lesion of Tooth, Gingival Inflammation, Gingival Bleeding, Dental Plaque
- Trial name
- WATER FLOSS (NCT06752291)
- Testing
- water flosser
- Where
- Malaysia
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Gingival Recession, Periodontal Plastic Surgery
Volumetric Changes After Free Gingival Graft: Tuberosity vs Palatal Donor Site (VolFGG-TP)
This randomized controlled clinical trial evaluated volumetric changes at recipient and donor sites following free gingival graft (FGG) surgery, comparing two different palatal donor regions.
- Trial name
- NCT07554625
- Testing
- Free Gingival Graft from Anterior Palatal Donor Site, Free Gingival Graft from Posterior Palatal / Tuberosity Donor Site
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hooman Hashemzadeh
Gingivitis
Stingless Bee Honey Mouth Rinse on Gingivitis
The currently used chemical mouth rinse, chlorhexidine, was prescribed widely among dental practitioners for its ability to kill bacteria.
- Trial name
- NCT07461155
- Testing
- mouth rinse, scaling, oral hygiene education and instruction
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ministry of Higher Education, Malaysia
Gingival Recession
Assessment of The Accuracy of Complete Crown 3D Superimposition Technique Relative to The Gold Standard Technique for Digital Quantification of Volumetric Soft Tissue Changes in The Esthetic Zone
The aim of this study is to assess the precision of the complete crown technique employed for the superimposition of 3D models, specifically in the quantitative volumetric evaluation of gingival tissues.
- Trial name
- NCT06457672
- Testing
- Group I, Group II
- Where
- Egypt
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- British University In Egypt
Periodontal Diseases
Evaluation of GCF And Salivary Ferritin, ALP And MMP-8 Levels of Individuals With Different Periodontal Diseases
The aim of this clinical study was to determine the levels of ferritin, alkaline phosphatase and matrix metalloproteinase-8 in the gingival crevicular fluid (GCF) and saliva samples were collected from 60 systemically healthy…
- Trial name
- NCT06561802
- Testing
- GCF and saliva obtaining
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Izmir Katip Celebi University
Gingivitis
Effects of Aloe Vera Toothpaste on Periodontal Parameters
This study aimed to assess the effects of Aloe Vera toothpaste on dental plaque and gingivitis. The single-blind cross-over clinical trial was conducted on 20 dental students (10 males and 10 females with a mean age of 24.5±4…
- Trial name
- NCT02235532
- Testing
- Foramen Herbal Aloe toothpaste, fluoride toothpaste
- Where
- Iran
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Islamic Azad University, Sanandaj
Periodontal Diseases
Periodontal Status and Endothelial Dysfunction in Patients With Polycystic Ovary Syndrome
Emerging research indicates a link between polycystic ovary syndrome (PCOS) and periodontal diseases, revealing the intricate relationship between oral health and systemic conditions.
- Trial name
- NCT06184412
- Where
- Spain
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana
Periodontitis, Gingivitis
GCF Bax and Bcl-xl Levels in Periodontitis
Intrinsic apoptosis pathway plays a critical role in the host immune defense and inflammation and its dysregulation is involved in various chronic diseases. Bcl-2 protein family primarly mediates this mitochondrial pathway.
- Conditions
- Periodontitis, Gingivitis, Periodontal Health
- Trial name
- NCT06443372
- Testing
- Clinical periodontal measurements, GCF sampling
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Gingivitis, Mucositis
Clinical, Immunological and Microbiological Evaluation of Experimental Gingivitis and Peri-implant Mucositis
The objective of this study is to evaluate, through clinical, microbiological and immunological tests, the changes during the experimental gingivitis and mucositis model, between teeth and implants, and between patients with a…
- Trial name
- NCT03713567
- Testing
- Experimentally induced plaque
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Campinas, Brazil
Gingivitis
Clinical Effects of Bacillus Containing Oral Hygiene Products on Gingivitis: a Randomized Controlled Trial
Aim: Evaluating the clinical effects of a Bacillus subtilis, Bacillus megaterium and Bacillus pumulus containing toothpaste, mouthwash and toothbrush cleaner versus a placebo in patients with generalized gingivitis.
- Trial name
- NCT02597192
- Testing
- probiotic oral hygiene products with Bacillus (PIP, Chrisal), oral hygiene products without Bacillus
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Gingivitis, Dental Plaque
The Effect of Mouthrinses Containing Bamboo Salt, Magnolia Bark and Centella Asiatica on Reducing Plaque and Gingivitis
This study aims to evaluate the effect of novel mouthrinse formulations containing bamboo salt, magnolia bark and centella asiatica extracts on gingivitis and dental plaque.
- Trial name
- NCT03047798
- Testing
- Mouthrinse
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Seoul National University
Periodontitis, Prolactin in GCF
The Effect of Non-surgical Periodontal Therapy on the Gingival Crevicular Fluid Levels of Prolactin Hormone in Patients With Periodontitis.
The present study will be conducted on fifty participants. All participants will receive a full-mouth clinical examination, and the following periodontal parameters will be recorded: Plaque Index (PI).
- Trial name
- NCT03726411
- Testing
- non-surgical periodontal therapy
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Eman Mohamed Amr
Dental Plaque, Gingivitis
Plaque Reduction Sesame-based Oil
The goal of this clinical trials to learn about potential additives in reducing dental plaque. The main questions it aims to answer is: is there a difference in the plaque reducing effect of oil pulling with sesame-based oil…
- Conditions
- Dental Plaque, Gingivitis, Oral Microbial Colonization
- Trial name
- NCT06841380
- Testing
- sesame-based oil, distilled water
- Where
- Austria
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Christine Zürcher
Gingival Recession
Effectiveness of Hyaluronic Acid on Multiple Adjacent Gingival Recessions Using a Coronally Advanced Flap
The goal of this clinical randomized trial is to examine the effectiveness of hyaluronic acid in treatment of multiple adjacent gingival recessions in 2 groups.
- Trial name
- NCT06330662
- Testing
- Testing the effectiveness of hyaluronic acid in experimental group using a coronally advanced flap compared to a control group using a coronally advanced flap only
- Where
- Croatia
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Andelina Sekelja
Gingivitis, Oral Disease
Metagenome Resilience in Experimental Gingivitis
This study aims to identify new biomarkers that indicate the resilience of individuals to developing oral disease. An 'experimental gingivitis' model will be employed in which subjects will refrain from oral hygiene in one…
- Trial name
- NCT05389124
- Testing
- Partial abstinence from oral hygiene
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Newcastle University
Periodontal Diseases
Evaluation of Galectin-3 Levels in GCF And Saliva of Patients With Different Periodontal Diseases
The aim of this study is to assess the levels of galectin-3 in the GCF and saliva in patient with gingivitis and patient with stage III periodontitis.
- Trial name
- NCT05281796
- Testing
- GCF obtaining, saliva obtaining
- Where
- Egypt
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Cairo University
Gingival Recession
Platelet Rich Fibrin in the Treatment of Palatal Wounds
In this study it will be investigated the usefulness of Platelet-Rich Fibrin (PRF) on in the epithelialized connective tissue graft palatal donor site healing acceleration and in the patient's morbidity reduction.
- Trial name
- NCT02438046
- Testing
- Palatal wound bandage
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- G. d'Annunzio University
Ultrasound, Oral Mucosa
Sonographic Imaging of Oral and Dental Anatomical Structures (A Pilot Study)
The overall purpose of this study is to establish an ultrasound technique to aid in oral and dental examination of soft and hard tissues.
- Conditions
- Ultrasound, Oral Mucosa, Gingival Recession, Alveolar Bone Loss
- Trial name
- NCT03657589
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Michigan
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