Clinical trials: Gingival Condition
Gingival Recession
To Compare Two Commonly Used Soft Tissue Grafting Techniques to Achieve Coronal Flap Advancement and Root Coverage
This study will compare two incision designs to allow for coronal gingival/mucosal flap advancement and tissue augmentation with acellular dermal matrix (ADM) graft around teeth with gingival recession and a lack of adequate…
- Trial name
- VISTA (NCT03566108)
- Testing
- VISTA, STA
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Esthetic Zone
Evaluation of Patient Morbidity and Root Coverage Outcomes of VISTA Versus CAF in Treating Gingival Recession
To evaluate and compare Vestibular Incision Subperiosteal Tunnel Access (VISTA) technique,with connective tissue graft; versus Coronally Advanced Flap (CAF) technique;with connective tissue graft, in treating gingival recession…
- Trial name
- VISTA (NCT06723314)
- Testing
- Vestibular Subperiosteal Tunnel Access vista
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Misr International University
Healthy, Adolescent
GumChucks vs Interdental Brushes in Plaque Removal.
This study compared two ways of cleaning between the teeth, Gumchucks (a new handled dental flossing system) and interdental brushes, in Lebanese adolescents aged 10-15 years.
- Conditions
- Healthy, Adolescent, Dental Plaque, Gingivitis
- Trial name
- NCT07140068
- Testing
- Handled dental flossing system (GumChucks®), Interdental Brush
- Where
- Lebanon
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Beirut Arab University
Gingivitis
A Proof-of-principle Clinical Study Investigating the Efficacy of an Experimental Dentifrice Containing Sodium Bicarbonate and Sodium Hyaluronate on Gingivitis
The aim of this study is to develop a daily use toothpaste containing sodium bicarbonate, sodium hyaluronate and sodium fluoride with the intention of providing improved/ fast gum healing.
- Trial name
- NCT04737538
- Testing
- Experimental Dentrifrice, Positive control dentifrice, Negative control dentifrice
- Where
- Canada
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Gingival Recession
PRF for Treating Maxillary Gingival Recession
This is a split-mouth, randomized, controlled clinical trial that aims to evaluate the clinical efficacy of platelet-rich fibrin (PRF) membranes in conjunction with coronally advanced flap (CAF) in treating maxillary gingival…
- Trial name
- NCT05267015
- Testing
- Gingival coverage using coronally advanced flap and a connective tissue graft, Gingival coverage using coronally advanced flap and platelet rich fibrin membranes
- Where
- Palestinian Territories
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Arab American University (Palestine)
Periodontoclasia, Gingiva; Injury
Use of Injectable-platelet-rich-fibrin (I-PRF) to Thicken Gingival Phenotype
The main objective of this study is to investigate whether the for individuals with thin gingival thickness who are susceptible to gingival recession, the investigators will use i-PRF with microneedle to increase gingival…
- Conditions
- Periodontoclasia, Gingiva; Injury, Condition, Blood Clot
- Trial name
- NCT03274674
- Testing
- I-PRF
- Where
- Turkey (Türkiye)
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Pain, Postoperative, Healing Wound
Evaluation of the Effects of Medicaments Used After Free Gingival Graft on Postoperative Complications.
In our study, three different medicaments were evaluated in terms of postoperative complications after free gingival grafting (FGG).
- Conditions
- Pain, Postoperative, Healing Wound, Hemorrhage, Analgesia
- Trial name
- NCT05386667
- Testing
- Majezik %0.25 oral spray, Aftamed oral spray, Crystalin oral spray
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Pamukkale University
Gingival Bleeding
The Effect of Mouthwash Containing Pomegranate Peel Extract and Chlorhexidine Mouthwash on Bleeding on Brushing
To evaluate the clinical effectiveness of mouthwash containing pomegranate peel extract and chlorhexidine mouthwash on bleeding on brushing and counting of streptococcus mutans among a group of Egyptian children with permanent…
- Trial name
- NCT02939092
- Testing
- Pomegranates peel extract, Chlorhexidine
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Periodontal Bone Loss, Chronic Periodontitis
Treatment of Intrabony Periodontal Defects With Enamel Matrix Derivatives and Autogenous Bone Graft
The present study aimed to evaluate the effects of enamel matrix derivatives either alone or combined with autogenous bone graft applied to intrabony defects in chronic periodontitis patients on clinical/radiographic parameters…
- Trial name
- NCT02218515
- Testing
- Open Flap Debridement, EmdogainⓇ(Enamel Matrix Derivative), EmdogainⓇEnamel Matrix Derivative+Autogenous Bone
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Haner Direskeneli, Prof
Gingivitis, Oral Disease
Individual Variability of Experimental Gingivitis Response
The study aims to investigate the genetic cause of the variability between individuals seen in the development of the gum disease, gingivitis.
- Trial name
- NCT05656417
- Testing
- Temporary cessation of all oral hygiene
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- King's College London
Gingivitis, Plaque, Dental
Cetylpyridium Chloride (CPC) Based Chewing Gum and Gingivitis
This placebo-controlled, double-blinded, randomized crossover study evaluates the plaque and gingivitis reducing capacity of Cetylpyridium Chloride (CPC) chewing gum, with mechanical oral hygiene.
- Conditions
- Gingivitis, Plaque, Dental, Periodontal Diseases
- Trial name
- NCT03219840
- Testing
- Cetylpyridinium Chloride (CPC) 0.09% + Xylitol chewing gum, Xylitol only chewing gum
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Gingival Overgrowth
The Effect of Platelet-Rich Plasma on Wound Healing After Gingivectomy
The aim of the study is to evaluate the effects of using droplet-form platelet-rich plasma (PRP), known to have positive effects during the intermediate healing process, on wound healing in areas left for secondary healing after…
- Trial name
- PRP (NCT07124143)
- Testing
- PRP
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Duygu Kilic
Dental Caries
Effect of Xylitol-Containing Chewing Gum With/Without Bicarbonate Versus Paraffin Pellet on Salivary pH
36 eligible participants will be randomly divided into three groups (n=12) according to the tested chewing gum (A), where (A1) represents participants exposed to xylitol chewing gum, (A2) represents participants exposed to…
- Trial name
- NCT03061422
- Testing
- Xylitol, xylitol with bicarbonate, paraffin
- Where
- Egypt
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pyogenic Granuloma of Gingiva
Effectiveness of Diode Laser and Sclerotherapy in Treatment of Oral Pyogenic Granuloma
To clinically assess the effectiveness of diode laser versus sclerotherapy in the treatment of oral pyogenic granuloma. A randomized-controlled clinical trial conducted on 20 patients with oral pyogenic granuloma.
- Trial name
- NCT05099081
- Testing
- diode laser application, intra-lesional injection of ethanolamine oleate
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Plaque, Gingivitis
The Efficacy of a Battery Toothbrush in the Reduction of Established Plaque and Gingivitis
A clinical research study design to compare the effectiveness of a battery toothbrush and dentifrice in reducing gingivitis and dental plaque in adults.
- Trial name
- NCT07224828
- Testing
- Total Active Prevention Fresh Toothpaste + Colgate Total Active Prevention Battery Toothbrush, Colgate Great Regular + Total Active Prevention Battery Toothbrush, Colgate Great Regular + standard reference flat trim toothpaste
- Where
- Puerto Rico
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Gingival Recession
The Use of Cyanoacrylate on Palatal Wound
The palatal donor site of autogenous free gingival grafts significantly influences the patient's morbidity. The purpose of this study was to evaluate the efficacy of cyanoacrylate on palatal wound healing and postoperative…
- Trial name
- NCT03273010
- Testing
- Free gingival graft, Cyanoacrylate application
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Ordu University
Gingival Recession, Periodontal Plastic Surgery
Volumetric Changes After Free Gingival Graft: Tuberosity vs Palatal Donor Site (VolFGG-TP)
This randomized controlled clinical trial evaluated volumetric changes at recipient and donor sites following free gingival graft (FGG) surgery, comparing two different palatal donor regions.
- Trial name
- NCT07554625
- Testing
- Free Gingival Graft from Anterior Palatal Donor Site, Free Gingival Graft from Posterior Palatal / Tuberosity Donor Site
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hooman Hashemzadeh
Colorectal Cancer
Simo Decoction and Acupuncture on POI in Colorectal Cancer
Colorectal cancer resection is one of the most common types of abdominal surgery. Though most patients undergoing colorectal resection show recovery of bowel movements within a week, some have prolonged intestinal paralysis or…
- Trial name
- SMD/POI (NCT02813278)
- Testing
- simo decoction, gum chewing
- Where
- China
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Guangxi Medical University
Peri-Implantitis, Peri-implant Mucositis
Peri-implant Conditions Mimic Periodontal Conditions
Except for patients with referred clinical bruxism and uncontrolled medical conditions, the study included 123 implants with implanted fixed prostheses that had lasted at least six months after functional prosthetic loading.
- Conditions
- Peri-Implantitis, Peri-implant Mucositis, Peri-implant Health, Periodontitis
- Trial name
- NCT06128850
- Testing
- disease
- Where
- Turkey (Türkiye)
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
Gingival Recession, Lack of Keratinized Gingiva
The Effect of Free Gingival Graft on Root Closure
Free gingival graft is a mucogingival surgical technique applied to increase keratinized gingival width and reduce gingival recession.
- Trial name
- NCT05604391
- Testing
- Free gingival graft placed apically, Free gingival graft placed coronally
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Berceste Guler
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