Clinical trials: Gingival Condition
Plaque, Dental, Gingivitis
Clinical Investigation to Assess the Efficacy of Manual Toothbrushes in the Reduction of Plaque and Gingivitis.
Qualified subjects will be enrolled and randomized to one of the two study groups based on their initial Plaque and Gingivitis scores. Subjects will be instructed to use the products according to the instructions provided.
- Trial name
- NCT06565897
- Testing
- Test regimen, Control regimen
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Gingivitis
Effectiveness of Brush DJ App in Improving Oral Hygiene Compliance of Fixed Orthodontic Patients
In this day and age, smartphones are occupying big portions of our lives. Expanding development of mobile applications focusing on delivering behavioral health intervention have intrigued us to know better about their efficacy.
- Trial name
- NCT05853276
- Testing
- Brush DJ app
- Where
- Malaysia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- IMU University, Malaysia
Periodontitis
Impact of Non-surgical Periodontal Treatment on Targeted Metabolomics
A double-blind randomized-controlled clinical trial is conducted in order to evaluate the impact of non-surgical periodontal treatment by means of minimally invasive approach MINST or Q-SI (quadrantwise) approach in subjects with…
- Trial name
- NCT07740447
- Testing
- Probing depth reduction
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- University of Catania
Gingival Recession
Effects of the Adjunctive Use of Hyaluronic Acid-based Gel With Coranally Advanced Flap in the Gingival Recession
The study aimed to evaluate the effect of Hyaluronic Acid-based gel use in addition to the coronally advanced flap (CAF) technique in type 1 gingival recession (RT1) on postoperative morbidity, clinical parameters, and patient…
- Trial name
- NCT07437885
- Testing
- Hyaluronic acid, Steril saline solution
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Ordu University
CHRONIC PERIODONTITIS
Efficacy of AloeVera Gel Gum Massaging and Adjunct to Scaling and Root Planing in Chronic Periodontitis Patients
Periodontal disease is a multifactorial disease caused by mainly bacterial, genetic, immunologically, and environmental factors.
- Trial name
- NCT03083535
- Testing
- Tooth Brushing, aloe vera Massaging, SRP with aloe vera massaging
- Volunteers
- 120 people
- Sponsor
- Government College of Dentistry, Indore
Dentin Hypersensitivity
Efficacy of Seventh Generation Bonding Agents as Short-Term Desensitizers Among Patients With Hypersensitivity
The world lacks a gold standard treatment for treating dentin hypersensitivity. Fluoride varnish is most commonly used as a treatment but it causes temporary discoloration of tooth structure and may cause irritation or burning of…
- Trial name
- NCT04225247
- Testing
- Single Bond Universal, Bifluorid 12, Xeno V+
- Where
- Pakistan
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Malocclusion Class II, Malocclusion, Angle Class I
Effect of Early Versus Late Premolar Extraction on Orthodontic Tooth Movement
The goal of this randomized controlled trial is to evaluate whether the timing of premolar extraction affects the rate of orthodontic space closure during en-masse anterior retraction.
- Trial name
- NCT07773389
- Testing
- Early Maxillary First Premolar Extraction, Late Maxillary First Premolar Extraction
- Where
- Pakistan
- Volunteers
- 26 people
- Sponsor
- Shifa College of Dentistry
Depigmentation Treatment, Depigmentation
Effect of Co-enzyme Q10 and Vitamin C Alone or in Combination After a Surgical Gingival Depigmentation
This study aims to assess the clinical effectiveness of Co-enzyme Q10 and Vitamin C, applied individually or in combination after surgical gingival depigmentation.
- Trial name
- Effect of Coe (NCT07677826)
- Testing
- surgical depigmentation, Coenzyme Q10, Vitamin C
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Pulpitis, Healthy
Measurement of Pro-resolving Inflammation Biomarkers in Saliva, Gingival Fluid, and Dental Pulp in Patients With Symptomatic Pulpitis and Healthy Controls
This observational study aims to better understand inflammation inside the dental pulp (the inner tissue of the tooth) in patients with symptomatic pulpitis compared with healthy individuals.
- Trial name
- SMART-PULP (NCT07450235)
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Université de Nantes
Gingival Recession, Localized
The Efficacy of Amnion Chorion Allograft in Management of Gingival Recession.
the main goal of this clinical trial is to test the efficacy of amnion Chorion allograft in managing gingival recession. The main questions it aims to answer are: Is it effective in treating gingival recession, and how it…
- Trial name
- NCT06508476
- Testing
- Amnion Chorion membrane, connective tissue graft
- Where
- Egypt
- Volunteers
- 28 people
- Sponsor
- Minia University
Osteoporosis, Osteopenia
Periodontal Disease and Post-menopausal Osteoporosis
The aim of this study was to investigate the levels of RANKL and Osteoprotegerin, and their relationship in gingival crevicular fluid of post-menopausal women with osteoporosis/osteopenia and chronic periodontitis simultaneously…
- Conditions
- Osteoporosis, Osteopenia, Periodontal Disease
- Trial name
- NCT02184962
- Where
- Argentina
- Volunteers
- 81 people
- Sponsor
- Universidad Nacional de Córdoba
Gingivitis
Non-Invasive Oral Biofilm Characterization
There is a need for toothpastes that more effectively remove oral plaque and prevent re-formation. The objective of this study is to map the development and resolution of clinical gingivitis using conventional clinical…
- Trial name
- NCT02178046
- Testing
- optical measurements
- Where
- United States
- Sponsor
- University of California, Irvine
Gingival Recession
MCAT Versus VISTA With Volume Stable Collagen Matrix in RT3 Gingival Recession
This study aims to compare MCAT technique (supraperiosteal approach with coronal advancement of flap) with VISTA technique(subperiosteal approach with coronal advancement of flap), Further, it may be hypothesized that…
- Trial name
- NCT06433986
- Testing
- Modified Coronally Advanced Tunnel (MCAT)Technique, Vestibular Incision Subperiosteal Tunnel Access (VISTA)Technique
- Where
- India
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Smoking Cessation
Comparison of Pharmacokinetic Profiles of 3 New Nicotine Gum Formulations With a Reference Gum
The purpose of the study is to compare the pharmacokinetic (PK) profiles and assess bioequivalence between three new nicotine gum formulations and a reference nicotine gum in healthy smokers.
- Trial name
- NCT02356913
- Testing
- Nicotine gum
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Fertin Pharma A/S
Periodontitis, Diabetes
Gingival Crevicular IL-34 and CSF-1 Levels in Patients With Periodontitis and Uncontrolled Type 2 Diabetes
Type 2 diabetes mellitus is a metabolic disorder. There is a bidirectional association between periodontal disease and DM. Currently there is no data relationship between CSF-1 and IL-34, periodontal disease and diabetes.The aim…
- Trial name
- NCT04891627
- Testing
- Gingival crevicular fluid
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Uşak University
Gingival Recession, Periodontal Diseases
The Effect of Enamel Matrix Derivatives on Root Coverage Esthetic Score
Subepithelial connective tissue grafts (SCTG) are accepted as the gold standard in covering denuded root surfaces. Combining enamel matrix derivatives (EMD) with periodontoplasic surgical operations is another method in covering…
- Trial name
- NCT03197610
- Testing
- enamel matrix derivatives
- Volunteers
- 19 people
- Sponsor
- Yuzuncu Yil University
Dental Plaque, Gingivitis
A Clinical Study Investigating the Efficacy of an Experimental Toothpaste Containing Stannous Fluoride in Improving Gingival Health
The aim of this study is to evaluate the ability of an experimental toothpaste, containing 0.454 percent (%) Stannous Fluoride (SnF2) to improve gingival health and reduce plaque accumulation compared to a regular fluoride…
- Trial name
- NCT07169188
- Testing
- Test Fluoride Toothpaste, Colgate Cavity Protection Toothpaste
- Where
- Canada
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- HALEON
Graft Shrinkage, Gingival Recession, Localized
Effect of i-PRF and LLLT on Free Gingival Graft Shrinkage
This randomized clinical trial aims to evaluate whether injectable platelet-rich fibrin (i-PRF) and low-level laser therapy (LLLT) can reduce graft shrinkage after free gingival graft procedures.
- Trial name
- NCT07303192
- Testing
- Free Gingival Graft (FGG), Injectable Platelet-Rich Fibrin (i-PRF), Low-Level Laser Therapy (LLLT)
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Kahramanmaras Sutcu Imam University
Gingivitis
Efficacy of the Addition of a Power Interdental Device to an Electric Toothbrush on Gingival Health.
The study is designed to evaluate the clinical changes in gingival health by measuring the reduction of gingival bleeding and inflammation over 4 weeks.
- Trial name
- NCT04003298
- Testing
- Electric toothbrush, Control
- Where
- Canada
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Water Pik, Inc.
Periodontitis
Change in Gingival Volume and Quality of Life Due to Initial Periodontal Therapy in Smokers
The aim of this study is to compare the dimensional changes of the gingiva due to initial periodontal therapy in non-smokers and cigarette smokers and to compare the oral health related quality of life of non-smokers and…
- Trial name
- NCT05719519
- Testing
- Initial periodontal therapy and 3D intraoral scanning
- Where
- Croatia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Rijeka
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