Clinical trials: Gingival Condition
Ileus
Effect of Chewing Gum on Post-operative Ileus (GUMPI)
The purpose of this study is to determine whether chewing gum post-operatively decreases the time to first flatus or defecation in patients undergoing spine surgery as a indirect indicator of post-operative ileus.
- Trial name
- GUMPI (NCT02847364)
- Testing
- chewing gum
- Where
- Lebanon
- Volunteers
- 100 people
- Sponsor
- American University of Beirut Medical Center
Oral Dysbiosis
Effects of a Composition on the Oral Microbiome, pH, Nitrite/Nitrate Ratio, Elastases and Inflammation in Oral Dysbiosis
Dysbiosis is a condition in which the normal function of an ecological net is altered. In dysbiosis a state of inflammation, a loss of hydration, a change in pH, a loss of the barrier function are all allies of key pathogens that…
- Trial name
- NCT05463484
- Testing
- Test composition Saliactive® (olive product, betaine and xylitol), Control
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Mucosa Innovations, S.L.
Peri-Implantitis, Periodontitis
Cellular and Molecular Inflammatory Mechanisms Leading to Bone Resorption in Peri-implantitis Vs Periodontitis
Recent data found that peri-implantitis may differ from periodontitis at the histological level in terms of extent and composition of the cellular components.
- Trial name
- DUOROPA (NCT02664675)
- Testing
- Crown lengthening, Open Flap Debridement
- Where
- 2 sites in France
- Volunteers
- 33 people
- Sponsor
- University of Paris 5 - Rene Descartes
Gingivitis, Plaque
A Study of Experimental Mouthwashes
The purpose of this study is to evaluate the safety and efficacy of experimental mouthwash formulations compared to a hydroalcohol control mouthwash and a positive control mouthwash for the reduction of gingivitis and plaque when…
- Trial name
- NCT05121909
- Testing
- Colgate (R) Cavity Protection Toothpaste, Colgate (R) Cello Toothbrush, Prototype 1 Mouthwash
- Where
- Canada
- Volunteers
- 274 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Consumer Inc. (J&JCI)
Plaque Induced Gingival Disease
Role of Herbal Based Mouthwashes in Plaque Control
Herbal medicine has been used for thousands of years. Traditional herbal medicine is used by an estimated 80% of the world's population for primary health care.
- Trial name
- mouthwash (NCT06711263)
- Testing
- Mouthwash Product
- Volunteers
- 80 people
- Sponsor
- Ajman University
Gingival Recession
Changes of Soft Tissue Grafting: A Randomized Study
To correct gum recession, patient's own tissue from the roof of the mouth is harvested and placed where there is root exposed. This is considered gold standard of treatment.
- Trial name
- NCT05633511
- Testing
- Split Mouth Design
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Tufts University
Gingivitis, Orthodontic Appliance Complication
Photodynamic Therapy in Patients With Gingivitis
The hypothesis to be tested in this study is whether photodynamic therapy (PDT) could favor the decontamination of these areas, as the photosensitizer and light are capable of reaching areas that these instruments have difficulty…
- Conditions
- Gingivitis, Orthodontic Appliance Complication, Photodynamic Therapy
- Trial name
- NCT04037709
- Testing
- scaling and root planing (SRP) + PDT
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Gingival Recession, Generalized
Ultrasonographic Vascular Supply
Pre-operative ultrasound enables visualization of mandibular arterial branches relevant to flap design in mucogingival surgery. This study documents the pre-and post operative course of these arteries in four CAF procedures using…
- Trial name
- NCT07727707
- Where
- Belgium
- Volunteers
- 4 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Gingivitis, Halitosis
Effect of Mouthwash Containing Camellia Sinensis Extracts on Oral Malodor
The purpose of this study is to determine effect of Mouthwash containing Camellia sinensis extracts on oral malodor and gingival inflammation in gingivitis subjects.
- Trial name
- NCT00932347
- Testing
- Camellia sinensis mouthwash
- Where
- 2 sites in Thailand
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Irreversible Pulpitis (Toothache)
Correlation Between the Clinical Presentation of Pulp and the Biological Mediators in Gingival Crevicular Fluid and the Inflamed Pulpal Tissue
The aim of the present study was to Correlate between the clinical presentation of pulp and the biological mediators in gingival crevicular fluid and the inflamed pulpal tissue.
- Trial name
- CBCPABMGCFFIPT (NCT07592455)
- Testing
- root canal treatment, samples from Gingival crevicular fluid
- Where
- Egypt
- Volunteers
- 36 people
- Sponsor
- Ain Shams University
Gingivitis
A Study Comparing the Interproximal Plaque and Gingivitis Effects of Three Interdental Cleaning Modalities
The purpose of this research study is to compare the interproximal plaque removal ability of Philips Sonicare Interproximal Cleaning Device to floss (Crest Glide) and Waterpik Waterflosser.
- Trial name
- PAU (NCT01307358)
- Testing
- Sonicare Interproximal (IP) Cleaning Prototype
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Periodontal Attachment Loss
ESWT on Human Gingival Fibroblasts
The idea of treating different deformities or diseases in the maxillofacial region with Extracorporeal Shockwave Therapy (ESWT) has recently become popular.
- Trial name
- ESWT (NCT05766293)
- Testing
- extracorporeal shockwave device, Fibroblast cell lines not subjected to shockwaves from extracorporeal shockwave device
- Where
- India
- Volunteers
- 20 people
- Sponsor
- Dr Prabhuji MLV
Gingivitis
Efficacy of Philips Sonicare Flexcare Platinum Toothbrush® Compared to Manual Brushing in Healthy Patients: a 1 Year Follow up
Professional oral hygiene has become a customary procedure in everyday dentistry. Both manual and sonic brushes are part of normal oral hygiene education practice.
- Trial name
- SONIMAN (NCT04558606)
- Testing
- Sonic Toothbrush, Manual Toothbrush
- Where
- Italy
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia
Chronic Periodontitis
Evaluation Efficacy of Melatonin Gel as Adjunctive Therapy in Chronic Periodontitis
This study was conducted to assess the benefit of locally delivered melatonin gel as adjunctive to scaling and root planning (SRP) in the treatment of chronic periodontitis.
- Trial name
- NCT05759416
- Testing
- Melatonin2%gel
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Tooth Loss, Recession, Gingival
Soft Tissue Volume Gain and Stability Comparing Palate and Tuberosity
The goal of this study is to compare clinical and histologically the soft tissue changes in terms of volume gain and stability around dental implants in cases where a subepithelial connective tissue graft from the palate or from…
- Trial name
- NCT03090906
- Testing
- Soft tissue augmentation palate, Soft tissue augmentation tuberosity, Intraoral optical scan
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Central Giant Cell Granuloma
Efficacy of Nasal Spray Calcitonin on Recurrence of Aggressive Central Giant Cell Granuloma
The main objective of this randomised clinical trial is to is to compare the frequency of recurrence between patients who received nasal spray calcitonin after curettage of Central Giant Cell Granuloma and without it.
- Trial name
- NCT02358304
- Testing
- nasal spray calcitonin
- Where
- Iran
- Volunteers
- 24 people
- Sponsor
- Shiraz University of Medical Sciences
Gingival Recession, Localized, Gingival Recession, Generalized
Pain Management After Free Gingival Graft Surgery
Keratinized gingiva reduces the risk of gingival disease and infection by protecting the tissue around the teeth and is therefore very important for gingival health.
- Conditions
- Gingival Recession, Localized, Gingival Recession, Generalized, Gingival Recession, Mucogingival Surgery
- Trial name
- NCT06675734
- Testing
- diclofenac sodium solution
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Istanbul Aydın University
Dental Plaque
Efficacy of Plaque Removal of a Novel Brushing Device
The purpose of this research study is to compare how a novel, automated mouthpiece-based toothbrushing device removes dental plaque compared to a manual toothbrush.
- Trial name
- NCT05038293
- Testing
- Automated mouthpiece-based toothbrush, Manual toothbrush
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Washington
Intravenous Blood Sampling, Pain and Anxiety
The Effect of Chewing Gum on Pain and State Anxiety During Intravenous Blood Sampling
This study was conducted to investigate the effect of chewing gum during intravenous blood sampling on pain and anxiety levels in individuals.
- Trial name
- NCT07892365
- Testing
- Chewing gum was done during the intravenous blood draw procedure
- Where
- Turkey (Türkiye)
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Dicle University
Gingival Recession, Gingival Diseases
Influence of Anatomical Factors Upon Root Coverage
Introduction: Gingival recession is a lesion characterized by the loss of attachment of root surface of the tooth, resulting in an apical migration of the gingival margin that occasionally generates aesthetic problems…
- Conditions
- Gingival Recession, Gingival Diseases, Periodontal Attachment Loss
- Trial name
- NCT04813302
- Testing
- Coronally advanced flap and connective tissue graft
- Where
- Spain
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
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