Clinical trials: Gingival Condition
Periodontitis
Biomarkers for Periodontitis Relapse
In this clinical study, we have collected GCF at diseased teeth and at the same time drawn blood, both before and at 3, 6 and 12 months after periodontal surgical treatment.
- Trial name
- NCT04663165
- Testing
- Periodontal surgery, Regenerative periodontal surgery
- Where
- 2 sites in Sweden
- Volunteers
- 21 people
- Sponsor
- Anders Holmlund
Gingival Pigmentation
Influence of Adjunctive Acids Use on Esthetic Outcomes of Gingival Melanin Depigmentation: A Periodontal-Operative Pilot Randomized Clinical Trial
This pilot randomized clinical trial aims to evaluate the effect of adjunctive acid application on the esthetic outcomes of gingival melanin depigmentation.
- Trial name
- GMDAcidRCT (NCT07708792)
- Testing
- Citric acid
- Volunteers
- 30 people
- Sponsor
- Dijlah University
Dental Caries, Gingivitis
Oral Hygiene Intervention Pilot Study
The main goals of this pilot study are to develop a nursing home-customized oral hygiene protocol, intended to be delivered primarily by dental hygienists and primary care providers, and to identify potential obstacles and…
- Trial name
- NCT02668809
- Testing
- oral health assessment, Questionnaires, Clinical Exam
- Where
- United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Leonardo Marchini
Gum Inflammation, Periodontal Diseases
Improving Gum Health Among Older Adults Using AI Based mHealth for Personalized OHI
Background: Many older adults in Hong Kong lack thorough tooth cleaning and regular dental check-ups, which can lead to plaque-induced gum diseases and systemic health issues.
- Conditions
- Gum Inflammation, Periodontal Diseases, Oral Hygiene, Oral Health
- Trial name
- NCT07187453
- Testing
- Personalized Oral Hygiene Advice using AI assisted mHealth Tool by Non-Dental Personnel
- Where
- Hong Kong
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Dental Plaque, Gingival Diseases
Effectiveness of Dental Health Education Methods on Oral Hygiene, Oral Health Care Self-Efficacy and Self-Esteem of Young Orphans
Background: Orphan children are at higher risk of developing oral diseases, compared to non-orphans. They also face various emotional, social, and psychological distresses which affect their general as well as oral health.
- Conditions
- Dental Plaque, Gingival Diseases, Oral Health, Self Efficacy
- Trial name
- NCT07771634
- Testing
- Conventional dental health education, Game based dental health education, Peer-group based dental health education
- Where
- Egypt
- Volunteers
- 264 people
- Sponsor
- Alexandria University
Gingivitis
Health Impact of L.Reuteri Consumption in Crew Members of a Naval Ship at Sea
This study is designed to evaluate the impact of the regular consumption of probiotic Lactobacillus reuteri-containing lozenges over a period of 42 days on parameters of oral and general health in crew members of a naval ship at…
- Trial name
- NAVLAC16 (NCT02775019)
- Testing
- Lactobacillus reuteri
- Where
- Germany
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Wuerzburg University Hospital
Gingival Pigmentation, Melanosis
Comparative Evaluation of Microsurgery vs Conventional Surgical Technique of Gingival Depigmentation
Gingiva being the most frequently pigmented tissue of the oral cavity challenges a lot of people with an esthetic concern. Increased production of melanin, a pigment produced by the melanocytes present in the basal and suprabasal…
- Trial name
- NCT05930392
- Testing
- Gingival depigmentation using microsurgery, Conventional surgical depigmentation
- Where
- India
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Healthy, Overweight
Study to Evaluate the Effect of Gum Acacia (FibregumTM) on Post-prandial Glucose, Insulin Levels and Food Intake
Study to evaluate the effect of gum acacia (FibregumTM) on post-prandial glucose and insulin levels and food intake in normal-weight and overweight subjects during a 2-7 weeks intervention period.
- Trial name
- NCT04515277
- Testing
- 40 g Gum acacia (FibregumTM), 20 g Gum acacia (FibregumTM), 0 g Gum acacia (FibregumTM)
- Where
- Germany
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Nexira
Gum Disease, Prediabetes
Improving Oral and Systemic Health in Individuals With Prediabetes Through Personalized Oral Hygiene Advice Provided by Dentists or by AI
Prediabetes is an intermediate stage before the development of diabetes, characterized by elevated blood glucose levels but lower than the diagnostic criteria of diabetes and is associated with multiple long-term complications.
- Trial name
- NCT06980701
- Testing
- AI OHI group, Dental professionals OHI group
- Where
- Hong Kong
- Volunteers
- 148 people
- Sponsor
- The University of Hong Kong
Menstrual Cycle-Associated Gingivitis
The Effect of Menstrual Cycle On IL-6, TNF-α And Periodontal Status
Aim: Women's menstrual cycle is controlled by the secretion of sex hormones. Sex steroid hormones are thought to be affect to periodontal tissues, wound healing, periodontal disease progression and bone turn over.
- Trial name
- NCT03281109
- Testing
- diagnosis
- Where
- Turkey (Türkiye)
- Volunteers
- 25 people
- Sponsor
- Yuzuncu Yil University
Periodontal Disease Stage 2
Interleukin-34 Level in Periodontal Disease
Aim of the study: 1. To investigate changes in the levels of Interleukin 34 (IL-34) in the Gingival crevicular fluid(GCF) of patients with stage II periodontitis patients before and after nonsurgical periodontal therapy and…
- Trial name
- NCT05962567
- Testing
- Non surgical periodontal therapy
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Gingival Recession, Periodontal Atrophy
Comparison Between Two Coronally Positioned Flap With Connective Tissue
The aim of this study is to evaluate the effectiveness of total root coverage between two coronally positioned flap technique in Miller recession Class I and II, in patients attending at "Universidad El Bosque" dental school…
- Trial name
- NCT01814592
- Testing
- coronally partial thickness flap plus connective tissue, coronally mucosal thickness flap
- Where
- Colombia
- Volunteers
- 72 people
- Sponsor
- Universidad El Bosque, Bogotá
Gingivitis, Periodontitis
SmartMouth Advanced Clinical Formula Clinical Research Design Protocol
The aim of this study is to provide evidence on the clinical efficacy of SmartMouth Advanced Clinical Formula mouthrinse in comparison to the efficacy of 0.12% chlorhexidine mouthrinse and a placebo mouthrinse.
- Trial name
- NCT02709785
- Testing
- SmartMouth Clinical DDS mouthrinse, 0.12% chlorhexidine rinse
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- St. Louis University
Gingival Enlargement
Comparative Evaluation of Hyaluronic Acid Spray and Low-Level Laser Therapy on Wound Healing Following Gingivectomy
Gingival enlargement may impair oral hygiene, esthetics, and periodontal health, and gingivectomy is commonly performed when non-surgical treatment is insufficient.
- Trial name
- NCT07034625
- Testing
- Low Level Laser Therapy, Hyaluronic Acid Spray
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Gingivitis
Dietary Diversities: Exploring the Influence of Keto Diet and Intermittent Fasting on Oral Health and Salivary Inflammatory Biomarkers
This study aims to investigate the impact of short term, two distinct dietary interventions, namely the Keto diet and Intermittent Fasting on oral health by measuring the severity of: Periodontal diseases (Gingivitis).
- Trial name
- NCT06597708
- Testing
- keto diet, intermittent fasting with calorie restriction
- Where
- Iraq
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Al-Mustansiriyah University
Gingival Recession
Low-intensity Laser Therapy in the Treatment of Gingival Recession
The purpose of this study was to evaluate the 6-month outcomes of applying low-intensity laser therapy associated with connective tissue grafts to treat gingival recession.
- Trial name
- LILT (NCT02118155)
- Testing
- Connective tissue graft
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- UPECLIN HC FM Botucatu Unesp
Gingival Recession, Mucogingival Surgery
Study of Hyaluronic Acid Used With Gum Surgery to Treat Gum Recession in Adults
Gingival recession is a common condition in which the gum tissue recedes, exposing the root surface of the tooth. This can lead to tooth sensitivity, higher risk of root decay, and aesthetic concerns.
- Trial name
- NCT07529340
- Testing
- Coronally Advanced Flap with Connective Tissue Graft, Cross-linked Hyaluronic Acid Gel
- Where
- Portugal
- Volunteers
- 34 people
- Sponsor
- Universidade do Porto
Recession, Gingival, Tissue Grafts
Topical Hyaluronic Acid Adjunctive Effects on Healing After Free Gingival Grafting in Smokers and Non-Smokers
Comparison of the healing of free gingival grafts applied to smokers and non-smokers and evaluation of the effect of hyaluronic acid gel on healing of the donor site.
- Trial name
- NCT07143760
- Testing
- Gengigel
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Istanbul University
Diverticulitis
Effect of Gum Arabic on Gastrointestinal Transit and Permeability
The study aims to determine the effect of gum arabic on gut bacteria and GI function.
- Trial name
- NCT03742076
- Testing
- High-dose prebiotic, Low-dose prebiotic
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Mayo Clinic
Oral Epithelial Dysplasia, Precancerous Conditions
Oral Epithelial Dysplasia Informational Needs Questionnaire
Background: Oral epithelial dysplasia (OED) is a condition with an increased risk of oral cancer. Due to the current changes in the factors associated with these diseases (because of human papillomavirus), it is expected that…
- Conditions
- Oral Epithelial Dysplasia, Precancerous Conditions, Precancerous Lesions, Oral Lichen Planus
- Trial name
- ODIN-Q (NCT04153266)
- Testing
- No intervention is planned for this study
- Where
- United Kingdom
- Volunteers
- 128 people
- Sponsor
- University College, London
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