Clinical trials: Gingival Condition
Tobacco Dependence
Bioequivalence Between Nicotine Replacement Products and Nicorette® Gum
Bioequivalence between oral nicotine replacement products and Nicorette® gum.
- Trial name
- NCT01113424
- Testing
- Nicotine, Nicorette® (Nicotine Gum)
- Where
- Sweden
- Volunteers
- 88 people
- Sponsor
- McNeil AB
Gingival Recession, Mucogingival Surgery, Gingival Recession
Combined Bilaminar Tunnel Technique in Treating Difficult Gingival Recessions
The goal of this clinical trial is to learn if the combined bilaminar tunnel technique works to treat anatomically difficult gingival recessions.
- Conditions
- Gingival Recession, Mucogingival Surgery, Gingival Recession, Root Coverage
- Trial name
- NCT07616960
- Testing
- mucogingival surgery
- Where
- Taiwan
- Volunteers
- 12 people
- Sponsor
- Choying Lin
Gingival Recession
PRF for Treating Maxillary Gingival Recession
This is a split-mouth, randomized, controlled clinical trial that aims to evaluate the clinical efficacy of platelet-rich fibrin (PRF) membranes in conjunction with coronally advanced flap (CAF) in treating maxillary gingival…
- Trial name
- NCT05267015
- Testing
- Gingival coverage using coronally advanced flap and a connective tissue graft, Gingival coverage using coronally advanced flap and platelet rich fibrin membranes
- Where
- Palestinian Territories
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Arab American University (Palestine)
Gynecologic Nursing, Pain
The Effect of Chewing Gum and Hot Compresses on Gynecologic Oncologic Surgery
The passage discusses the recovery of gastrointestinal (GI) function after abdominal surgery and the potential impact on patient comfort.
- Trial name
- NCT06196138
- Testing
- Gum, Hot Compress
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Istanbul Medeniyet University
Dental Plaque, Gingivitis
Six Month Plaque and Gingivitis Study Using Colgate Total Toothpaste
The objective of this randomized, single center, parallel clinical research study is to evaluate the comparative efficacy performance of three dentifrices -Colgate Total Toothpaste, Parodontax Toothpaste and Colgate Cavity…
- Trial name
- NCT02080273
- Testing
- Colgate Cavity Protection toothpaste, Colgate Total toothpaste, Parodontax toothpaste
- Where
- Thailand
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Gingivitis, Plaque, Dental
Antiplaque Efficacy of Two Novel Commercially Available Herbal Toothpastes.
Maintaining proper oral hygiene is essential in the prevention of oral as well as general illness. The use of herbal medicine in dentistry is growing exponentially over the years.
- Trial name
- NCT05363956
- Testing
- salvadora, Eucalyptus Oil
- Where
- United Arab Emirates
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ajman University
Free Gingival Graft, Survey and Questionnaire
Free Gingival Graft Patients' Treatment Perception and Experience
Free gingival graft (FGG) is a common and effective periodontal procedure used to improve gum health; however, it can involve challenges such as postoperative pain and discomfort due to the requirement of a secondary donor site.
- Conditions
- Free Gingival Graft, Survey and Questionnaire, Postoperative Pain
- Trial name
- NCT07568327
- Testing
- Free Gingival Graft
- Where
- Turkey (Türkiye)
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Istanbul Aydın University
Gingival Diseases
Centella Asiatica (Gotukola) Mouthwash as an Adjunct to Mechanical Plaque Control
This study evaluates the adjunctive use of Centella Asiatica (gotukola) to scaling in the reduction of plaque and gingival inflammation.
- Trial name
- NCT02827305
- Testing
- Gotukola, Scaling
- Where
- India
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Sri Hasanamba Dental College and Hospital
Chronic Periodontitis, Type 2 Diabetes Mellitus
Leptin and Visfatin in Diabetic Patients With Periodontitis Before and After Periodontal Therapy
1. Are adipokines involved in pathogenesis of periodontal disease in diabetic patients? 2. Does their level change after periodontal therapy?
- Trial name
- NCT02174146
- Testing
- non-surgical periodontal therapy
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Gingival Recession
MINST Versus Conventional Subgingival Instrumentation In RT1 Gingival Recession
Gingival recession is a common condition and its extent and prevalence increase with age. Majority of patients probably present with localized and shallow gingival recession that need a specific treatment because they are…
- Trial name
- NCT06044727
- Testing
- Minimally invasive non surgical periodontal therapy, Conventional subgingival instrumentation
- Where
- India
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Oral Health
Evaluation of a Daily Oral Care Lozenge on Oral Health and Quality of Life in Older Adults
The assessment of a daily oral care lozenge (PTx800) will be compared to a placebo control in a cohort of older adults who visit adult senior centers and who also have mild to moderate gingivitis.
- Trial name
- NCT03693027
- Testing
- PTx800 lozenges
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Primal Therapies Inc.
Constipation
Evaluation of Acacia Gum on Microbiome and Bowel Function in Participants With Chronic Constipation
Proof of concept study to investigate the impact of a food supplement consisting of Acacia gum on changes of gut microbiota and production of short chain fatty acids.
- Trial name
- NCT04382456
- Testing
- acacia gum
- Where
- Germany
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Alpinia Laudanum GmbH
Gingivitis, Plaque
ToothWave Calculus Reduction and Accumulation Prevention Study
The objective of the study is to evaluate the safety and efficacy of the home-use device ToothWave (Model H7001) for calculus reduction and the prevention of calculus accumulation.
- Conditions
- Gingivitis, Plaque, Calculus, Dental
- Trial name
- NCT04596761
- Testing
- RF-utilizing powered toothbrush
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Home Skinovations Ltd.
Gingivitis, Periodontal Diseases
Toothpaste With Sodium Carbonate in Patients With Gingivitis
Sodium carbonate has several properties that may be beneficial in the management of bacterial biofilm in gingivitis patients. The aim of this RCT study is to clinically evaluate the clinical properties of two toothpaste…
- Trial name
- NCT06224699
- Testing
- Toothpaste Product
- Where
- Italy
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Catania
Dental Caries, Gingivitis
Shifts in the Oral Biofilm of Patients With Known Oral Health Risk Factors
This study is observational only and is intended to evaluate changes in the makeup and function of bacteria naturally present in the mouth during treatment with braces to straighten teeth.
- Trial name
- NCT02885064
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Periodontal Diseases, Gingival Recession Localized Moderate
Hydroxyapetite Nanoparticles and Tricalcium Phosphate Nanoparticles Loaded on Platelet Rich Fibrin Membranes for Treatment of Gingival Recession
The "Glossary of the American of Periodontology" defines gingival recession (GR) as the apical movement of the gingival margin beyond the cement-enamel junction.
- Conditions
- Periodontal Diseases, Gingival Recession Localized Moderate, Nano-hydroxyapatite, Nano Tricalcium Phosphate
- Trial name
- NCT07088809
- Testing
- Nanocrystalline hydroxyapatite loaded in PRF+ coronally advanced flap, Nanocrystalline tricalcium phosphate (NcTCP) loaded in PRF+ coronally advanced flap
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Enas Elgendy
Gingival Recession, Generalized, Gingival Recession, Localized
Clinical and Histological Evaluation of Subepithelial Connective Tissue Graft Maturation at Different Healing Timepoints, With and Without Topical Application of a Polynucleotide- and Hyaluronic Acid-Based Gel
This study evaluates whether a 9-week healing interval is sufficient for subepithelial connective tissue graft (SCTG) maturation after palatal harvesting, and whether topical application of a polynucleotide and hyaluronic acid…
- Conditions
- Gingival Recession, Generalized, Gingival Recession, Localized, Wound Healing, Palate; Wound
- Trial name
- NCT07708051
- Testing
- polynucleotide and hyaluronic acid gel, subepithelial connective tissue graft harvesting
- Volunteers
- 15 people
- Sponsor
- University of Sao Paulo
Tooth Crowding
Effect of Force Magnitude on Canine Retraction and Gingival Crevicular Fluid Proteome
This study aims to examine the effect of force levels in orthodontic treatment during canine retraction. Force levels refer to the pressure applied by the orthodontic devices to move teeth.
- Trial name
- NCT06668194
- Testing
- Light Force (150g Niti Coil), Heavy Force (400 g Niti coil)
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- UConn Health
Gingival Recession
Soft Tissue Augmentation Using Deepithelialized Free Gingival Graft Compared to Connective Tissue Graft in Management of Miller Class I and II Gingival Recession.
The aim of this study will be to clinically assess the soft tissue augmentation achieved by the de-epithelialized free gingival graft with coronally advanced flap versus the subepithelial connective tissue graft with coronally…
- Trial name
- NCT03213483
- Testing
- Coronally advanced flap and subepithelial connective tissue graft, Coronally advanced flap and deepithelialized free gingival graft
- Where
- Egypt
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Cairo University
Gingivitis, Periodontal Inflammation
Influence of Probiotics on Clinical Parameters, the Oral Microbiome and the Immune System During an Orthodontic Treatment in Adult Patients
Orthodontic treatment with fixed appliances can be necessary to correct malocclusions in adolescence or adulthood. It its known that orthodontic treatment induces aseptic pseudo-inflammatory reactions.
- Conditions
- Gingivitis, Periodontal Inflammation, Orthodontic Appliance Complication
- Trial name
- NCT04606186
- Testing
- Lactobacillus reuteri Prodentis®-lozenges (DSM 17938, ATCC PTA 5289)
- Where
- Germany
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Erlangen-Nürnberg
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