Clinical trials: Gingival Inflammation and Bleeding
Gingiva; Infection, Plaque, Dental
Role of Herbal Dentifrices in the Management of Plaque Induced Gingivitis
The clinical cross over study involves the use of two herbal based dentifirices moringa and miswak and its efficacy in reducing plaque induced gingivitis.
- Trial name
- NCT04830176
- Testing
- dentifrice
- Where
- India
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ajman University
Dental Plaque, Gingival Bleeding
Comparison Between Interdental Brush and Water Floss on Plaque Accumulation and Gingival Inflammation in Patients Undergoing Fixed Orthodontic Treatment.
The goal of this clinical trial is to test the ability of water flosser to remove plaque and reduce gingival inflammation in patients undergoing fixed orthodontic treatment.
- Trial name
- NCT07240428
- Testing
- Interdental brush, Water floss
- Where
- Jordan
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- King Abdullah University Hospital
Periodontal Diseases, Gingival Diseases
Novel Dental Gel as an Adjunct to Scaling and Root Planing
This study will evaluate the use of Livionex Dental Gel (LDG) as a home care product in reducing probing pocket depth (PD) beyond the effect achieved by the current standard of care with SRP in periodontitis patients.
- Conditions
- Periodontal Diseases, Gingival Diseases, Gingival Pocket, Gum Bleed
- Trial name
- NCT05384132
- Testing
- SRP + Livfresh Dental Gel, SRP + standard flouride dentifrice
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Periodontal Disease, Gingival Inflammation and Bleeding
Efficacy of Oral Hygiene Regimens in Patients Undergoing Non-Surgical Periodontal Treatment
The objective of this clinical study is to evaluate the efficacy of multi-component oral hygiene regimens as adjunctive to non-surgical periodontal treatment in patients with stage II periodontitis.
- Trial name
- PEREG (NCT07803484)
- Testing
- Active Oral Hygiene Regimen
- Where
- 2 sites in Brazil
- Volunteers
- 100 people
- Sponsor
- Colgate Palmolive
Periodontal Diseases, Gingivitis
Randomized Trial of a Gum Health Formulation
The purpose of this study is to evaluate the safety and efficacy of a newly formulated foaming gel product on gingivitis and/or moderate periodontitis when used with or without the GLO Science accelerating device (GLO Device)…
- Conditions
- Periodontal Diseases, Gingivitis, Periodontitis, Halitosis
- Trial name
- NCT03196648
- Testing
- Gingival health formulation in an accelerating device, Gingival health formulation on a toothbrush, OTC fluoride toothpaste
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Glo Science, Inc.
Plaque, Gingivitis
A Clinical Trial to Test the Effect of Marketed Mouth Rinses on Decreasing Plaque and Gum Inflammation
The reduction of existing plaque and gum inflammation will be evaluated using two marketed mouth rinses along with tooth brushing after 21 days of use compared to a placebo mouth rinse.
- Trial name
- NCT02233998
- Testing
- Mouth Rinse 1, Mouth Rinse 2, Mouth Rinse 3
- Where
- Canada
- Volunteers
- 158 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Consumer and Personal Products Worldwide
Gingivitis, Gingival Bleeding
Clinical Assessment of the Safety and Efficacy of Flaus Electric Flosser on Plaque and Gingivitis Compared to a Manual Toothbrush
The purpose of this study to evaluate the safety and efficacy of an electric flosser (interproximal cleaning aid), when used with a manual toothbrush and fluoride toothpaste, on gingivitis reduction and dental plaque removal.
- Conditions
- Gingivitis, Gingival Bleeding, Dental Plaque
- Trial name
- NCT07805148
- Testing
- Device: Electric Flosser, Manual toothbrush
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Flaus, Inc
Plaque Induced Gingivitis, Mouth Diseases
Anti-inflammatory and Anti-plaque Efficacies of Mouth Rinse Containing Hyaluronic Acid and Hydrogen Peroxide
The goal of this clinical trial is to test efficiency of using mouth rinse containing (H2O2 and HA) over a period of two weeks to control on gingival inflammation and plaque accumulation through measuring the clinical periodontal…
- Conditions
- Plaque Induced Gingivitis, Mouth Diseases, Bleeding Gum, Periodontal Diseases
- Trial name
- NCT05787600
- Testing
- Perhyal rinse, Chlorhexidine mouthwash
- Where
- Iraq
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Anxiety Disorders, Oral Disease
Effect of Trait Anxiety in Women on Oral Health Status and Oral Health Care-Seeking Behavior
Trait anxiety is the tendency of an individual to perceive environmental stimuli such as different events and situations as threatening; it's stable and reflects how an individual generally feels.
- Conditions
- Anxiety Disorders, Oral Disease, Periodontal Diseases, Periodontal Attachment Loss
- Trial name
- NCT04274855
- Where
- Egypt
- Volunteers
- 451 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Bleeding Gum, Gingivitis
Clinical Investigation of Bleeding Reduction Efficacy on Toothpaste Containing 1.05% Chitosan
The purpose of this study is to assess the bleeding reduction efficacy of toothpaste containing 1.05% Chitosan compared to a regular fluoride toothpaste, and compared to a toothpaste containing 67% bicarbonate.
- Trial name
- NCT06955871
- Testing
- Toothpaste containing 1.05% Chitosan, Silica-based NaF Toothpaste, Toothpaste with 67% bicarbonate
- Where
- China
- Volunteers
- 134 people
- Sponsor
- Colgate Palmolive
Halitosis, Mouth Disease
Efficacy of Resveratrol Containing Mouthwash in Reducing Halitosis Related Porphyrymonas Gingivalis.
The aim of the study: To assess the efficacy of antioxidant (resveratrol) mouthwash in reducing the level of p. gingivitis and oral malodor over 7 day period among undergraduate dental student patients from Mustansiriyah…
- Conditions
- Halitosis, Mouth Disease, Plaque Induced Gingival Disease, Bleeding Gum
- Trial name
- NCT06882564
- Testing
- resveratrol mouthwash, Chlorhexidine mouthwash (0.2%)
- Where
- Iraq
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Al-Mustansiriyah University
Gingival Inflammation, Plaque
Stannous Fluoride Toothpaste for Reduction and Treatment of Gingivitis
This study evaluated the efficacy of a stannous fluoride toothpaste compared to a sodium fluoride control toothpaste in reducing gingivitis, bleeding, and plaque over a 12-week period.
- Conditions
- Gingival Inflammation, Plaque, Bleeding
- Trial name
- NCT07640399
- Testing
- Sodium Fluoride Dentifrice, Stannous Fluoride Toothpaste (SnF)
- Where
- Canada
- Volunteers
- 133 people, healthy volunteers welcome
- Sponsor
- Church & Dwight Company, Inc.
Periodontitis, Gingivitis
Diagnostic Accuracy of Rapid Non-clinical Screening Tests for Early Detection of Periodontitis
Gum disease is the 6th most prevalent disease of mankind. It is a non-communicable non-resolving inflammation; if untreated it leads to tooth loss and inability to chew properly.
- Trial name
- NCT03928080
- Testing
- Bleeding on brushing
- Where
- China
- Volunteers
- 408 people, healthy volunteers welcome
- Sponsor
- The European Research Group on Periodontology (ERGOPerio)
Gingivitis, Gum Disease
Efficacy of Devices in Maintaining Oral Health and Managing Periodontal and Interproximal Tissues
The aim of the study was to assess the acceptability of the assisted individual and compliance with home use, as well as their clinical impact on the plaque index (PI) and bleeding on probing (BOP), with monthly reassessments…
- Conditions
- Gingivitis, Gum Disease, Oral Health
- Trial name
- NCT07520994
- Testing
- Group 1: use of the rubber interdental brush (picks) at baseline for 3 months, Group 2: use of the traditional bristle interdental brush at baseline for 3 months
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Roma La Sapienza
Gingivitis
A Clinical Trial to Test the Effect of an Experimental Mouth Rinse on Gum Disease
Subjects will be given special instructions about eating, smoking and taking care of their teeth during the 18 hours before they come to the dentist's office for screening.
- Trial name
- NCT01821261
- Testing
- Mouth Rinse 19668-012, Mouth Rinse 500347078842, Toothpaste 035000513007
- Sponsor
- Johnson & Johnson Consumer Inc. (J&JCI)
Dental Plaque, Patient Reported Outcome
The Antiplaque and Antigingivitis Effect of Pure Green Tea Mouth Wash Compared to Placebo and Essential Oils Mouth Washes
The goal of this clinical trial is to to evaluate the antiplaque and antigingivitis effect of pure green tea mouthwash compared to placebo and essential oils mouthwashes in healthy patients.
- Conditions
- Dental Plaque, Patient Reported Outcome, Gingival Inflammation and Bleeding, Gingival Inflammation
- Trial name
- NCT07364565
- Testing
- Pure Green Tea Mouthwash, Listerine Total Care Mouthwash, Listerine Green Tea Mouthwash
- Where
- Jordan
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- King Abdullah University Hospital
Gingival Inflammation, Plaque
The Effectiveness of Brushing and Flossing Sequence on Control of Plaque and Gingival Inflammation
This study evaluates the effectiveness of brushing and flossing sequence in the control of dental plaque and gingival inflammation.
- Conditions
- Gingival Inflammation, Plaque, Gingival Bleeding, Plaque Control
- Trial name
- RCT (NCT03989427)
- Testing
- Brushing first and Flossing later (BF), Flossing first and Brushing later (FB)
- Where
- Malaysia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Melaka Manipal Medical College
Gingivitis, Bleeding Gum
Efficacy of Hyaluronic-acid and Hydrogen-Peroxide Mouthwash in Gingivitis Treatment
A clinical study to evaluate the efficacy and safety of a mouthwash containing Hydrogen Peroxide, Sodium Hyaluronate and Glycine in the prevention and management of complications associated gingivitis by film forming action.
- Trial name
- NCT04438421
- Testing
- Filming mouthwash formulation, enriched with Hydrogen Peroxide and Hyaluronic Acid, Chlorhexidine mouthwash
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- University of Milan
Dental Implantation, Peri-implant Mucositis
Periodontal Effects of Orthodontic Mini-Screws
Orthodontic mini-screws (TADs) are commonly used to provide temporary anchorage and prevent unwanted tooth movement during orthodontic treatment.
- Conditions
- Dental Implantation, Peri-implant Mucositis, Orthodontic Anchorage Procedures, Gingival Inflammation and Bleeding
- Trial name
- NCT07052747
- Testing
- Clinical periodontal assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Dr. Mehmet Selim Yildiz
Gingivitis, Dental Plaque
Next Science Antimicrobial Mouth Rinse Study
To assess the effect of a test antimicrobial oral rinse from Next Science on the prevention of oral biofilm formation and thereby preventing gingivitis by monitoring the oral microbial flora and measuring gingival inflammation…
- Trial name
- NCT03154021
- Testing
- Next Science OTC Oral Rinse with Essential Oils, OTC Oral Rinse Control
- Where
- 2 sites in United States
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- University of Florida