Clinical trials: Gingival Recession Defects
Gingival Recession
Platelet Rich Fibrin and Autologous Fibrin Glue
Platelet-rich fibrin (PRF) and Autologous Fibrin Glue (AFG) are fibrin preparation derived from human blood samples and are used in regenerative dentistry.
- Trial name
- NCT03734458
- Testing
- Group A - PRF plus AFG with a CAF, Group B - PRF only with a CAF, Group C - CTG with a CAF
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Gingival Recession
A Clinical Trial Testing Root Coverage With Acellular Dermal Matrix in Thin and Thick Gingival Biotypes
Gingival recession is a common defect among the American population. It is also a major cause for root decay, hypersensitivity, contributes to tooth mobility and low self-esteem.
- Trial name
- NCT03057730
- Testing
- Acellular Dermal Matrix
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Tufts University
Graft Pain, Gingival Recession
MEBO Ointment and Hyaluronic Acid Gel in the Management of Pain After Free Gingival Graft Harvesting
Postoperative pain as well as bleeding are the most common complications after palatal graft harvesting also postsurgical swelling have been reported , Although different agents were used to protect the denuded areas on the…
- Trial name
- NCT03728244
- Testing
- MEBO ointment, Hyaluronic Acid gel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Gingival Recession
Inverted T-shape Free Gingival Graft for Treatment of RT2 / RT3 Gingival Recession Defects
The aim of this study is to compare the use of T-inverted shape Free Gingival Graft with Free Gingival Graft for improving the clinical attachment, gain partial root coverage, and improve Keratinized tissue width in recession…
- Trial name
- NCT06615687
- Testing
- Inverted T shape Free Gingival Graft, Free Gingival Graft
- Where
- Egypt
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Cairo University
Gingival Recession
Treatment of Multiple Gingival Recessions With a MCAF or a MCAT and a Collagen Matrix
In a recent meta-analysis, Graziani et al. reported that despite the "ideal" treatment for multiple gingival recession defects is not yet identified, there are some indirect suggestions from the analyzed data that, in comparison…
- Trial name
- NCT04225351
- Testing
- MCAF+CM, MCAT+CM
- Where
- Italy
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Università Vita-Salute San Raffaele
Gingival Recession
OrACELL™ vs. Connective Tissue in Miller Class 3 Defects
The purpose was to compare root coverage outcomes between autogenous connective tissue graft (CTG) and decellularized human dermis (OrACELL™) in areas of facial gingival recession.
- Trial name
- NCT03226600
- Testing
- OrACELL, Connective Tissue Graft
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
Gingival Recession, Localized
Tuberosity Versus Palatal Connective Tissue Graft on the Treatment of Single Maxillary Recession-type Defects
The goal of this randomized clinical study is to assess the root coverage outcomes and patient morbidity following the treatment of single maxillary recession-type defects using a coronally advanced flap (CAF) combined with a…
- Trial name
- NCT06404762
- Testing
- tSCTG+ CAF, pSCTG+ CAF
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Gazi University
Gingival Recession, Gingival Recession, Localized
Coronally Advanced Tunnel Combined With Xenogenic Dermal Matrix and L-PRF
Gingival recession is the exposure of the root surface due to the gum margin moving away from the crown of the tooth. It's common in adults and becomes more prevalent and severe with age.
- Conditions
- Gingival Recession, Gingival Recession, Localized, Mucogingival Defects
- Trial name
- CAF+XADM (NCT06634043)
- Testing
- Coronally Advanced Tunel + ADM (Novomatrix®), Coronally Advanced Tunel + ADM (Novomatrix®) + L-PRF
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Andres Matteo Pascual La Rocca
Gingival Recession
Connective Tissue Grafting for Single Tooth Recession & the Impact of the Thickness of the Palatal Harvest Tissue
The purpose of this study is to test if the thickness of the graft taken from the roof of the mouth, has a significant effect on the amount of attached tissue and the amount of root coverage that are attained when treating a…
- Trial name
- NCT03032094
- Testing
- connective tissue graft
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Columbia University
Root Coverage, Tunneling Technique
Root Coverage With Connective Tissue Graft Associated With VISTA Versus Tunnel Technique
Several techniques were proposed in the literature to solve the problems associated with gingival recession. Root coverage was mainly indicated for esthetic concern, however, it might also be indicated for treatment of root…
- Conditions
- Root Coverage, Tunneling Technique, VISTA Technique, Sub Epithelial Connective Tissue Graft
- Trial name
- NCT03690635
- Testing
- VISTA (vestibular incision subperiosteal tunnel acess)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Gingival Recession, Generalized
Cor Adv Flap Plus Ac Derm Matrix in Thin Phenotype Multiple Recessions
Clinical evaluation of conventional and modified coronally advanced flaps combined with acellular dermal matrix graft
- Trial name
- NCT03883438
- Testing
- Modified coronally advanced flap and acellular dermal matrix graft
- Where
- 4 sites in Azerbaijan, Brazil and 2 more
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Aziz Aliyev Azerbaijan State Advanced Training Institute for Doctors
Insufficient Keratinized Tissue, Gingival Recession
Cyanoacrylate Versus Sutures for Free Gingival Graft Stabilization
This randomized controlled clinical trial evaluated the effectiveness of butyl-cyanoacrylate tissue adhesive compared with conventional sutures for stabilization of free gingival grafts.
- Conditions
- Insufficient Keratinized Tissue, Gingival Recession, Mucogingival Defects
- Trial name
- NCT07359300
- Testing
- Free Gingival Graft Stabilization With Butyl-Cyanoacrylate, Free Gingival Graft Stabilization With Sutures
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Yeditepe University
Gingival Recession
Tunnel vs. CAF for the Treatment of Multiple Gingival Recessions
Many studies have compared the tunnel technique and coronally advanced flap in the treatment of single and multiple recessions. However, there is a lack of evidence that compared both techniques in combination with a connective…
- Trial name
- NCT05122468
- Testing
- Connective tissue Harvest and CAF, Connective tissue Harvest and Tunnel
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidad Complutense de Madrid
Gingival Recession
Clinical Evaluation of Injectable Platelet Rich Fibrin With Connective Tissue Graft for the Treatment of Deep Gingival Recession Defects.
Aim: The aim of this study was to determine whether the combined connective tissue graft (CTG) with injectable platelet rich fibrin (i-prf) with coronally advanced flap (CAF) improved root coverage of deep Miller Class I or II…
- Trial name
- NCT04032405
- Testing
- CAF+CTG+i-prf
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Gingival Recession
Gingival Recession Treatment With Concentrated Growth Factor(CGF)
Platelet concentrates(PC) are used in the field of periodontology and implantology for the content necessary key cells and growth factors to accelerate healing and to provide regeneration.
- Trial name
- NCT03020732
- Testing
- test groups, control groups
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Gazi University
Gingival Recession, Lack of Keratinized Gingiva (Disorder)
Progenitor Potential of Mesenchymal Stem Cells in Palatal Tissue Harvested From Molar and Premolar Sites
The primary purpose of this protocol is to isolate, investigate and compare the regenerative and differentiation potential of mesenchymal stem cells (MSC's) in the gingival (gum) tissue harvested from two different locations from…
- Trial name
- NCT03570333
- Testing
- progenitor potential of Gingival Mesenchymal cells
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Gingival Recession
Platelet-rich Fibrin and Connective Tissue Graft in Recession Treatment
The aim of the trial is to evaluate the effectiveness of coronally advanced flap (CAF)+connective tissue graft(CTG)+platelet-rich fibrin(PRF) combination in Miller I and II recession treatment by comparing with CAF+CTG.
- Trial name
- NCT02397122
- Testing
- platelet-rich fibrin, connective tissue graft, coronally advanced flap
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Kırıkkale University
Gingival Recession
Amnion Membrane Versus DFGG Using the Tunneling Technique in Management of Gingival Recession Defects.
Treatment of gingival recession is indicated mainly for esthetic reasons and keratinized tissue augmentation (Zucchelli and Mounssif, 2015).
- Trial name
- NCT06146855
- Testing
- Tunneling procedure with Amnion Membrane, Tunneling procedure with De-epithelialized Free Gingival Graft
- Where
- Egypt
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Cairo University
Gingival Recession, Localized
Er,Cr:YSGG Laser For Recipient Bed Bio-modification And Connective Tissue Harvesting in Treatment of Gingival Recession
A clinical and radiographic evaluation of using Erbium, Chromium, Scandium, Gallium and Garnet (Er,Cr:YSGG) laser in recipient site bio-modification and de-epithelialized connective tissue graft harvesting compared to…
- Trial name
- NCT03200392
- Testing
- laser root surface conditioning & laser DGG harvesting, laser root surface conditioning & blade DGG harvesting, blade DGG harvesting
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Misr International University
Gingival Recession, Mucogingival Surgery
Microsurgical Instruments and Magnification May Enhance Treatment Outcomes Of Laterally Moved, Coronally Advanced Flap in Miller Class III Isolated Recession Defects
The benefits of microsurgical approaches in periodontal therapy have been described. The main focus of this study is to determine if using microsurgical LMCAF technique would improve the outcomes of the therapy for the Miller…
- Trial name
- NCT02281071
- Testing
- laterally moved coronally advanced flap with microsurgical instruments and x2.5 loupe
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cukurova University