Clinical trials: Gingival Recession Defects, open to volunteers
Gingival Recession, Gingival Recession, Localized
Coronally Advanced Tunnel Combined With Xenogenic Dermal Matrix and L-PRF
Gingival recession is the exposure of the root surface due to the gum margin moving away from the crown of the tooth. It's common in adults and becomes more prevalent and severe with age.
- Conditions
- Gingival Recession, Gingival Recession, Localized, Mucogingival Defects
- Trial name
- CAF+XADM (NCT06634043)
- Testing
- Coronally Advanced Tunel + ADM (Novomatrix®), Coronally Advanced Tunel + ADM (Novomatrix®) + L-PRF
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Andres Matteo Pascual La Rocca
Gingival Recession, Plastic Surgery
Non-Inferiority of Fibroguide Collagen Membrane Compared to Autologous Connective Tissue Graft for Coverage of Multiple Adjacent Recession. Multicenter Trial.
This study deals with coverage of multiple denuded roots. The current standard treatment requires surgical correction and uses soft tissue taken from the roof of the mouth to enhance results.
- Trial name
- NCT07083050
- Testing
- Volume stable collagen matrix, Autologous Connective Tissue Graft from the Hard Palate
- Where
- 2 sites in Italy, Spain
- Volunteers
- 160 people
- Sponsor
- Maurizio Tonetti
Single Recession Defects (RT2)
Clinical Evaluation Comparing Tunneled Coronally Advanced Flap and Modified Coronally Advanced Tunnel With Connective Tissue Graft for Managing Single Gum Recession
The technique under investigation aims to provide effective root coverage while offering the advantage of being less invasive.
- Trial name
- NCT07239180
- Testing
- Modified Coronally Advanced Tunnel with Connective Tissue Graft, Tunneled Coronally Advance Flap with Connective Tissue Graft
- Volunteers
- 24 people
- Sponsor
- Cairo University
RT II Gingival Recession
Hyaluronic Acid and Polynucleotides With Connective Tissue Graft and Coronally Advanced Flap for RT II Gingival Recession
This case series will evaluate the effectiveness of injectable hyaluronic acid combined with polynucleotides as an adjunct to coronally advanced flap and connective tissue graft in patients with RT II gingival recession.
- Trial name
- NCT07771244
- Testing
- Coronally Advanced Flap with Connective Tissue Graft and Hyaluronic Acid/Polynucleotides
- Where
- Egypt
- Volunteers
- 12 people
- Sponsor
- Cairo University
Mucogingival Defects, Recession, Gingival
Clinical Evaluation of Gingival Biotype Changes Using a Coronally Advanced Flap (CAF) in Combination with Leucocyte and Platelet- Rich Fibrin (L-PRF) Membranes of Different Thickness for the Treatment of RT1 Gingival Recession: a Randomized Controlled Clinical Trial.
Gingival thickness plays a key role not only in the etiology but also in the treatment of gingival recessions. More recently, authors reported that as the gingival thickness decreases, the gingival recession severity increases .
- Conditions
- Mucogingival Defects, Recession, Gingival, Gingival Recession, Mucogingival Surgery, L-PRF
- Trial name
- NCT06701799
- Testing
- CAF+ L-PRF 1 mm, CAF+ L-PRF 2 mm
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- G. d'Annunzio University
Postoperative Pain, Mucogingival Defects
Management of Postoperative Pain Following Free Gingival Graft Harvesting Using Ora-Aid Versus Acrylic Palatal Stent
This randomized clinical trial evaluates the effectiveness of Ora-Aid oral wound dressing compared to an acrylic palatal stent in managing postoperative pain following free gingival graft harvesting.
- Conditions
- Postoperative Pain, Mucogingival Defects, Gingival Recessions
- Trial name
- NCT07523802
- Testing
- Ora-Aid Oral Wound Dressing, Acrylic Resin Palatal Stent
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Cairo University
Gingival Recession, Localized
Effectiveness of Tuberosity Micro Connective Tissue Graft for Treatment of Multiple Adjacent Gingival Recession Defects
The objective of this project is to compare post-operative pain associated with palatal and tuberosity donor sites for micro-CTG, and to evaluate the outcomes in both the donor and recipient sites.
- Trial name
- NCT06650072
- Testing
- modified coronally advanced tunnel technique combined with multiple palatal micro connective tissue grafts, modified coronally advanced tunnel technique combined with multiple tuberosity micro connective tissue grafts
- Volunteers
- 30 people
- Sponsor
- Göteborg University
Gingival Recession Defects
The Effect of Vertically Coronally Advanced Flap With Sub-epithelial Connective Tissue Graft Versus Coronally Advanced Flap With Sub-epithelial Connective Tissue Graft on Gingival Recession.
The aim of this randomized clinical trial will be to assess the change in recession depth after using a vertically coronally advanced flap with sub-epithelial connective tissue graft compared to a coronally advanced flap with…
- Trial name
- NCT07801677
- Testing
- Vertically Coronally Advanced flap combined with sub-epithelial connective tissue graft, Coronally Advanced flap combined with sub-epithelial connective tissue graft
- Where
- Egypt
- Volunteers
- 26 people
- Sponsor
- Cairo University
Gingival Recessions
Influence of Keratinized Tissue Width and Attached Gingiva Width on Root Coverage in Patients With Recession Defects: A Prospective Clinical Study
To evaluate the association between the width of keratinized tissue and attached gingiva with root coverage outcomes in RT1 gingival recession defects of maxillary and mandibular anterior teeth treated with subepithelial…
- Trial name
- NCT07576439
- Testing
- Vestibular incision subperiosteal tunnel access with connective tissue graft in treating RT 1 gingival recession defects
- Where
- India
- Volunteers
- 30 people
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Gingival Recession, Localized
Effectiveness of Micro Connective Tissue Graft for Treatment of Multiple Adjacent Gingival Recession Defects
The objective of this project is to evaluate 1-year outcomes of treatment of MAGRD using a modified coronally advanced tunnel technique (MCAT) with either conventional CTG (control group) or micro-CTG (test group).
- Trial name
- NCT06030947
- Testing
- Coronally Advanced Flap combined with a Connective Tissue Graft, Coronally Advanced Flap combined with micro Connective Tissue Graft, Division of the Connective Tissue Graft into multiple micro Connective Tissue Grafts
- Where
- United Arab Emirates
- Volunteers
- 30 people
- Sponsor
- Göteborg University
Periodontitis, Gingival Recession, Localized
Efficacy of a Gel Containing Polynucleotides and Hyaluronic Acid in Supraosseous Periodontal Defects Treated with the Single Flap Approach
Treatment of supraosseous defects (SD) may be challenging due to their limited regenerative potential. When located in aesthetic areas, treatment may result in a gingival recession increase with consequent patients' concerns in…
- Conditions
- Periodontitis, Gingival Recession, Localized, Aesthetic Perception, Aesthetic Outcomes
- Trial name
- SFA-SD (NCT06897085)
- Testing
- viscoelastic gel containing polynucleotides and hyaluronic acid, No intervention
- Volunteers
- 70 people
- Sponsor
- Azienda Unità Sanitaria Locale (A.U.S.L.) Ferrara, Italy
Single RT1 Gingival Recession With no Loss of Interproximal Attachment
Adding Effect of Cross-linked Hyaluronic Acid to Microneedling After Coronally Advanced Flap in Isolated RT1 Recession
In patients with single RT1 recessions and thin gingival phenotype, does adding cross-linked hyaluronic acid by microneedling after CAF surgery produce greater gingival thickness gain and higher probability of complete root…
- Trial name
- NCT07520539
- Testing
- cross-linked hyaluronic acid, Microneedling
- Volunteers
- 22 people
- Sponsor
- Cairo University