Clinical trials: Gingivitis
Periodontal Disease, Periodontal Diseases Inflammation
Comparative Evaluation of Oxygen-enriched and Chlorohexidine Mouthwashes as an Adjunct to Non-surgical Periodontal Therapy and Its Efficacy on Gingival Inflammation, Plaque Scores and Patient-reported Outcomes
comparison between CHX and oxygen-enriched mouthwash
- Conditions
- Periodontal Disease, Periodontal Diseases Inflammation, Gingivitis, Mouthwash
- Trial name
- NCT07861880
- Testing
- CHX mouthwash, Oxygen-enriched mouthwash
- Where
- Egypt
- Volunteers
- 72 people
- Sponsor
- Cairo University
Periodontal Diseases, Periodontal Diseases Inflammation
Retinal and Choroidal Changes in Periodontal Disease
Advanced PeriodontitisIn this cross-sectional study, the relationship between periodontal disease severity and retinal and choroidal structural changes was evaluated using SD-OCT.
- Conditions
- Periodontal Diseases, Periodontal Diseases Inflammation, Retinal Thickening
- Trial name
- NCT07856901
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Zeliha Başak Çakır Erdil
Plaque Induced Gingival Disease
Mouthwashes for Gingivitis: Comparing a Hydrogen Peroxide-Hyaluronic Acid Mix, Hyaluronic Acid, and Chlorhexidine, A Triple-Blind Clinical Trial
This randomized, triple-blind clinical trial is designed to evaluate the efficacy of four different mouthwash formulations - hydrogen peroxide with hyaluronic acid, hyaluronic acid alone, chlorhexidine, and placebo - in four…
- Trial name
- TRIPLE-G (NCT07031388)
- Testing
- 1-Hydrogen peroxide and hyaluronic acid, 2- Hyaluronic acid, Chlorhexidine
- Where
- Iraq
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ramziyah Hayder Bakr
Plaque-Induced Gingivitis
Pain Perception After Manual and Ultrasonic Periodontal Debridement in Patients With Gingivitis
This study compared immediate pain perception following manual and ultrasonic supragingival periodontal debridement in patients with plaque-induced gingivitis.
- Trial name
- NCT07847736
- Testing
- Manual Supragingival Debridement, Ultrasonic Supragingival Debridement
- Where
- Turkey (Türkiye)
- Volunteers
- 206 people
- Sponsor
- Recep Tayyip Erdogan University
Allogeneic Stem Cell Transplantation
Xylitol BSI Multisite - Reduction of Bloodstream Infections From Oral Organisms in Pediatric Stem Cell Transplant
Bloodstream infections (BSI) caused by bacteria translocating across injured oral mucosa are a significant cause of morbidity and mortality in patients undergoing stem cell transplantation (SCT).
- Trial name
- NCT05579639
- Testing
- Xylitol
- Where
- 3 sites in United States
- Volunteers
- 256 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Rheumatoid Arthritis (RA), Periodontitis
Effects of Nonsurgical Periodontal Treatment on GCF Calprotectin and IL-10 in Rheumatoid Arthritis
This study evaluates the relationship between rheumatoid arthritis and periodontal health and examines the effects of nonsurgical periodontal treatment on clinical periodontal findings and gingival crevicular fluid biomarkers.
- Conditions
- Rheumatoid Arthritis (RA), Periodontitis, Gingivitis
- Trial name
- NCT07844564
- Testing
- Non-surgical Periodontal Treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Gingivitis
Clinical Study Examining the Control of Plaque and Gingivitis
The objective of this six-month clinical investigation is to evaluate the efficacy of a silica-free meridol toothpaste versus Colgate Cavity Protection Toothpaste in the control of established dental plaque and gingivitis.
- Trial name
- NCT07842978
- Testing
- Silica Free Meridol, Meridol, Colgate Dental Product
- Where
- China
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Plaque, Dental Plaque
Clinical Evaluation of a Toothpaste for Dental Plaque Reduction and Prevention of Gum Problems
Qualified subjects will be enrolled and randomized to either one of the three study groups described above based on their initial modified gingivitis and plaque scores.
- Conditions
- Plaque, Dental Plaque, Gingivitis
- Trial name
- NCT07842991
- Testing
- 0.45% SnF HW with NaF (1450 F), 67% Bicarbonate with NaF (1400 F), Colgate Cavity Protection Toothpaste
- Where
- Italy
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Plaque, Gingivitis
Study to Investigate Toothpaste on Antibacterial Effects in the Different Regions of the Mouth
The clinical study will examine the effects of brushing with randomly assigned test toothpaste on the bacteria on the dental plaque, tongue, cheek, gum surface, and in saliva
- Trial name
- NCT07458464
- Testing
- stannous fluoride toothpaste, 0.76% Sodium Monofluorophosphate (Na MFP) toothpaste
- Where
- 2 sites in Thailand
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Dental Plaque, Oral Hygiene
Smartphone App Versus Verbal Motivation for Oral Hygiene in Fixed Orthodontic Patients
This study looked at whether a smartphone app can help patients with fixed braces keep their teeth cleaner than usual spoken advice alone.
- Conditions
- Dental Plaque, Oral Hygiene, Gingivitis, Malocclusion
- Trial name
- iTeeth (NCT07835022)
- Testing
- Smartphone application for oral-hygiene motivation (iTeeth Orthodontics), Conventional verbal oral-hygiene motivation
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Atlas University
Gingivitis, Periodontitis
TBC1D15 / Rab7 / Fis1 Pathway in Periodontal Disease
This study will look at certain proteins in the fluid found around the gums (called gingival crevicular fluid, or GCF) of people with healthy gums, gingivitis (mild gum inflammation), or periodontitis (more severe gum disease).
- Trial name
- NCT07835477
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Inonu University
Reducing Gingivitis, Clinical Effect
Effectiveness of Coconut Oil Pulling and Moringa Mouthwash Versus Chlorhexidine in Reducing Gingivitis in Diabetic Children
Gingivitis is a common and reversible inflammatory condition, mainly caused by dental plaque, and is particularly prevalent among children.
- Trial name
- NCT07826390
- Testing
- Chlorhexidine mouthwash, Moringa olfera mouthwash, coconut oil pulling
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Amira Yehia Zakaria
Plaque, Gingivitis
The Efficacy of a Battery Toothbrush in the Reduction of Established Plaque and Gingivitis
A clinical research study design to compare the effectiveness of a battery toothbrush and dentifrice in reducing gingivitis and dental plaque in adults.
- Trial name
- NCT07224828
- Testing
- Total Active Prevention Fresh Toothpaste + Colgate Total Active Prevention Battery Toothbrush, Colgate Great Regular + Total Active Prevention Battery Toothbrush, Colgate Great Regular + standard reference flat trim toothpaste
- Where
- Puerto Rico
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Critically Ill, Oral Health Care
Professional Oral Care and Staff Education in Critically Ill Patients
This study evaluated oral health in critically ill patients admitted to two intensive care units in Budapest, Hungary, and examined whether professional oral care and education of intensive care staff could improve oral hygiene.
- Conditions
- Critically Ill, Oral Health Care, Critical Illness, Oral Care Performance
- Trial name
- NCT07831564
- Testing
- Professional Oral Care, Standard Oral Care, ICU Staff Oral Care Education
- Where
- 2 sites in Hungary
- Volunteers
- 161 people
- Sponsor
- Semmelweis University
Gingival Inflammation, Dental Plaque
A Study to Measure the Effect of a Toothpaste Containing Proteins and Enzymes and a Fluoride Toothpaste on Gingival Health
This study is a double-blind, randomised, parallel group efficacy study. A minimum of 240 healthy female and male participants aged 18-70 years will be enrolled onto the study according to the inclusion/exclusion criteria.
- Trial name
- NCT06932211
- Testing
- Toothpaste containing proteins and enzymes, Control fluoride toothpaste
- Where
- China
- Volunteers
- 251 people, healthy volunteers welcome
- Sponsor
- Unilever R&D
Gingival Inflammation, Dental Plaque Accumulation
Evaluation of the Anti-plaque Effect of a Bioflavonoid-based Antiseptic Mouthwash
This study evaluates the antiplaque efficacy of a bioflavonoid-based mouthwash compared to a positive control (0.12% chlorhexidine mouthwash).
- Trial name
- NCT07824388
- Testing
- Bioflavonoid mouthwash, Chlorhexidine 0.12% mouthwash
- Where
- Spain
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Barcelona
Gingivitis
Personalized 3D Visualization for Oral Hygiene and Motivation in Adults With Gingivitis
This study evaluated whether personalized three-dimensional images of possible future changes in the gums could improve oral hygiene and motivation in adults with gingivitis.
- Trial name
- NCT07826715
- Testing
- Conventional Oral Hygiene Education, Three-Dimensional Animation-Based Oral Hygiene Education, Personalized Three-Dimensional Visualization With Motivational Discussion
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
Gingivitis Infection, Dental Plaque
Chlorhexidine vs Essential Oil Mouthwash for Plaque Control
Dental plaque is a sticky film of bacteria that forms on teeth and can lead to gum disease if it is not removed regularly. Brushing and flossing help control plaque, but many people also use a mouthwash to help clean areas that…
- Trial name
- NCT07822256
- Testing
- Chlorhexidine Gluconate Mouthwash, Essential Oil mouthwash
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Rehman Medical Institute - RMI
Gingival Inflammation, Gingival Bleeding
Evaluation of a Toothpaste Containing a Gum Health Active in Participants With Gingival Problem
The primary objective of this clinical study is to evaluate the impact on gingival health when participants switch to a fluoride toothpaste without gum-health actives for 4 weeks after using a proven gum-health toothpaste for 13…
- Conditions
- Gingival Inflammation, Gingival Bleeding, Dental Plaque
- Trial name
- NCT07415733
- Testing
- Test Toothpaste, Control Toothpaste
- Where
- Indonesia
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Unilever R&D
Periodontal Diseases, Gingivitis
ORAL HYGIENE, PERIODONTAL STATUS AND QUALITY OF LIFE
This cross-sectional study aims to evaluate the relationship between oral hygiene habits, periodontal status, and oral health-related quality of life in adult individuals.
- Conditions
- Periodontal Diseases, Gingivitis, Periodontitis
- Trial name
- NCT07530978
- Testing
- Oral Health Assessment and OSHIP-Perio Questionnaire
- Where
- Turkey (Türkiye)
- Volunteers
- 463 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University