Clinical trials: Glaucoma Open-angle
Primary Open Angle Glaucoma, Myopia
Diagnostic Innovations in Glaucoma Study
The overarching goal of our research study is to evaluate changes in visual function and optic nerve topography (the structure of the back of the eye) in patients with glaucoma (increased susceptibility to pressure inside the eye…
- Trial name
- DIGS (NCT00221897)
- Where
- United States
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Primary Open Angle Glaucoma, Secondary Open Angle Glaucoma
Early Diagnosis, Pathogenesis and Progression of Open Angle Glaucoma
The Erlangen Glaucoma Registry is a clinical registry for cross sectional and longitudinal observation of patients with open angle glaucoma (OAG) or glaucoma suspect, founded in 1991.
- Conditions
- Primary Open Angle Glaucoma, Secondary Open Angle Glaucoma, Ocular Hypertension
- Trial name
- NCT00494923
- Where
- Germany
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- University of Erlangen-Nürnberg Medical School
Glaucoma, Open-Angle, Chronic Wounds
Absorption and Safety of Topical Timolol to Treat Chronic Wounds
Topical timolol has been used primarily as eye drops to treat glaucoma for many years. Recent clinical experience has broadened its off-label use for a number of skin conditions, including slow-healing wounds.
- Trial name
- NCT04903366
- Testing
- Timolol Maleate
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- VA Northern California Health Care System
Fuchs Endothelial Corneal Dysfunction, Open Angle Glaucoma (OAG)
A Study to Assess Brillouin Hydration Mapping for the Evaluation of Ocular Tissues and Diseases
The overall goal of this study is to develop Brillouin microscope as a novel tool for measuring biomechanical and hydration properties of human tissues in vivo.
- Conditions
- Fuchs Endothelial Corneal Dysfunction, Open Angle Glaucoma (OAG), Dry Eye Disease (DED), Keratoconus
- Trial name
- NCT07780890
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Glaucoma, Glaucoma, Open-Angle
Prevalence of Glaucoma and Normative Data of Ocular Biometry in Elderly Population in Bangkok
The BANMOP eye study is an ophthalmic subproject of the Bangkoknoi Model Project (BANMOP), a community-based initiative integrating electronic health databases with population surveys to sup-port context-specific health promotion…
- Conditions
- Glaucoma, Glaucoma, Open-Angle, Glaucoma, Suspect, Glaucoma, Angle-Closure
- Trial name
- BANMOP (NCT07763288)
- Where
- Thailand
- Volunteers
- 1,470 people, healthy volunteers welcome
- Sponsor
- Siriraj Hospital
Open Angle Glaucoma
Micropulse Laser Trabeculoplasty (MLT) Versus Selective Laser Trabeculoplasty (SLT) for Treatment of Open Angle Glaucoma
The purpose of this study is to evaluate the effectiveness of a new laser (called Micropulse Laser Trabeculoplasty or MLT) in the treatment of glaucoma compared to the conventional laser presently used which is called selective…
- Trial name
- NCT01956942
- Testing
- Micropulse Laser Trabeculoplasty, Selective Laser Trabeculoplasty
- Where
- United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- David Belyea
Effect of Drug
Comparison of Preserved and Preservative-free Latanoprost 0.005% in Primary Open Angle Glaucoma and Ocular Hypertensive Patients, at Guinness Eye Centre, Lagos.
It is a randomised, double-blinded clinical trial in which consenting participants who meet the inclusion criteria would be randomised into 2 groups.
- Trial name
- NCT05606796
- Testing
- Latanoprost 0.005% Ophthalmic Solution
- Where
- Nigeria
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Uzoma Chinyei Joan
Open Angle Glaucoma
Efficacy of Simbrinza and Rocklatan vs Cosopt and Latanoprost
A randomized, multi-site, parallel-group, prospective study of patients who are adults with a diagnosis of mild to moderate open-angle glaucoma (OAG), currently on an on-label use of combination topical medication of Cosopt and…
- Trial name
- NCT06883123
- Testing
- Simbrinza 0.2%-1% Ophthalmic Suspension, Rocklatan 0.02%-0.005% Ophthalmic Solution, Cosopt PF 2%-0.5% Ophthalmic Solution
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Prairie Eye Center
Glaucoma, Inflammatory Response
Impact Post-operative Treatment on Intraocular Pressure Post-SLT on Patients With Primary Open-angle Glaucoma
The present study's main objective is to assess if there is a significant difference between either of the treatments frequently used in post-op, namely a topic cortisone-based treatment, an non-steroidal anti-inflammatory drug…
- Trial name
- SLT (NCT01058278)
- Testing
- Selective Laser trabeculoplasty
- Where
- Canada
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- CHU de Quebec-Universite Laval
Open Angle Glaucoma, Ocular Hypertension
Additivity Study: Additive Effect on Eye Pressure of Azopt and Alphagan P to Travatan
The purpose of this study is to compare the additive effect on eye pressure of Azopt and Alphagan P to Travatan.
- Conditions
- Open Angle Glaucoma, Ocular Hypertension, Pseudoexfoliation Syndrome
- Trial name
- NCT00121147
- Testing
- Travatan, Azopt, Alphagan P
- Where
- 21 sites in United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Hermann Eye Center
Glaucoma, Open-Angle
The Effect of Pseudoexfoliation on Choroidal Thickness in Open Angle Glaucoma
Purpose: To investigate the effect of pseudoexfoliation (PEX) on choroidal thickness in primary open-angle glaucoma (POAG). Methods: This prospective, randomized study included 30 POAG patients and 30 PEX glaucoma patients with…
- Trial name
- NCT03373942
- Testing
- Choroidal thickness measurements with SD-OCT device
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Emine Deniz Egrilmez
GLAUCOMA 1, OPEN ANGLE, D (Disorder)
Spectral Domain Optical Coherence Tomography Analysis for Glaucoma
The aim of this study is to examine whether there is a difference in macular ganglion cell complex thickness and retinal nerve fiber layer thickness in early-stage Primary open angle glaucoma and normal tension glaucoma with…
- Trial name
- NCT01612416
- Testing
- RS-3000 OCT measurements
- Where
- Turkey (Türkiye)
- Volunteers
- 169 people, healthy volunteers welcome
- Sponsor
- Inonu University
Primary Congenital Glaucoma
The Genetic Characteristics in South Korean Patients With Primary Congenital Glaucoma
Primary congenital glaucoma, which presents at birth or in infancy, if left untreated, may threaten vision. The incidence of congenital glaucoma varies among different geographic locations and ethnic groups.
- Trial name
- NCT01020721
- Where
- South Korea
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Primary Open Angle Glaucoma, Healthy Subjects
Efficacy of 24-hour Intraocular Pressure Fluctuation Recording With the SENSIMED Triggerfish Contact Lens Sensor
The objectives of this study are to assess the safety and effectiveness of the SENSIMED Triggerfish® (TF) device in continuous recording of relative fluctuation in intraocular pressure (IOP).
- Trial name
- NCT01390779
- Testing
- SENSIMED Triggerfish
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Sensimed AG
Anesthesia, Intraocular Pressure
Establishment of an Anaesthetic Protocol for Examinations for Children With Glaucoma or Suspected Glaucoma
Correct measurement of the intraocular pressure of children with glaucoma or suspected glaucoma is essential for diagnosis and therapy.
- Conditions
- Anesthesia, Intraocular Pressure, Glaucoma, Suspect, Pediatric Glaucoma
- Trial name
- eyeBIS (NCT03972852)
- Where
- Germany
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Johannes Gutenberg University Mainz
Glaucoma, Intraocular Pressure
The Measurement of Intraocular Pressure in Normal Children Under General Anesthesia With and Without Nitrous Oxide and Anesthetic Eye Drops
Pediatric glaucoma is a rare but potentially blinding condition where the pressure in the eye is too high. Diagnosis is based on intraocular pressure (IOP) and assessment of the optic nerve, cornea and other structures.
- Conditions
- Glaucoma, Intraocular Pressure, Anesthesia
- Trial name
- IOP (NCT01925391)
- Testing
- Tono-pen XL Applanation tonometer + Ocu-film +
- Where
- 2 sites in United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Miami
Glaucoma
Posterior Cornea in Primary Open Angle Glaucoma
Characterization of posterior corneal changes in primary open angle glaucoma patients, using Scheimpflug examination.
- Trial name
- NCT02356094
- Testing
- Pentacam
- Where
- Portugal
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Centro Hospitalar do Baixo Vouga
Glaucoma
Analysis of the Eye in Patients With Primary Open-Angle Glaucoma and a Visual Field Defect in One Eye
The study aims to further understand glaucoma pathogenesis and progression by utilizing enhanced depth imaging optical coherence tomography to visualize and measure lamina cribrosa in vivo and segmentation technology to…
- Trial name
- NCT02622191
- Testing
- Spectral domain Optical Coherence Tomography
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Wills Eye
Open Angle Glaucoma
Does the Optic Disc Grading Done Visually by Your Doctor Agree With Optic Nerve Testing Which is Done by Machines?
The purpose of this study is to determine how well the DDLS (Disc Damage Likelihood Scale) (which is a method used by the eye doctor to evaluate how healthy the optic nerve is) measures up to the standard glaucoma tests: OCT…
- Trial name
- NCT00430287
- Where
- United States
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Wills Eye
Glaucoma, Primary Open Angle
Adaptive Optics Retinal Imaging
The objective of the study is to collect and assess adaptive optics (AO) retinal images from human subjects in support of projects to demonstrate, advance, and enhance clinical use of AO technology.
- Trial name
- NCT05370287
- Testing
- oxygen inhalation, Adaptive optics imaging
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Food and Drug Administration (FDA)