Clinical trials: Glucose Metabolism Disorders (Including Diabetes Mellitus)
Diabetes Mellitus, Glucose Intolerance
Prevalence of Glucose Intolerance and Risk Factors in Ethiopian Immigrants in Israel; Follow-up Study.
High risk population: Screening for impaired glucose tolerance.
- Trial name
- NCT01402362
- Where
- Israel
- Volunteers
- 550 people, healthy volunteers welcome
- Sponsor
- Hillel Yaffe Medical Center
Glucose, Glucose Metabolism Disorders (Including Diabetes Mellitus)
The Effect of Kombucha on Blood Sugar Levels in Humans
As a phase 0 clinical trial, we will learn how kombucha influences glucose metabolism in humans.
- Conditions
- Glucose, Glucose Metabolism Disorders (Including Diabetes Mellitus), Blood Sugar; High
- Trial name
- NCT04051294
- Testing
- Commercial kombucha tea, Brewed kombucha tea, Control: Tea
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Diabete Type 2, Disability Physical
Accessible and Inclusive Diabetes Telecoaching Self-Management Program
The purpose of this study is to develop and pilot test an accessible and inclusive Artificial Intelligence (AI)-assisted, individualized, family-focused lifestyle modification intervention (AI4DM) for glycemic control in people…
- Trial name
- NCT04927377
- Testing
- AI4DM, Attention-control
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- University of Alabama at Birmingham
Angina Pectoris, Diabetes Mellitus, Type 2
Study Protocol for Rosiglitazone Versus Gliclazide in Diabetics With Angina
The principle objective of the trial is to compare rosiglitazone to gliclazide in patients with type 2 diabetes mellitus and chronic stable angina to see how the subjects' angina status changes.
- Trial name
- NCT00225342
- Testing
- Rosiglitazone, Gliclazide (Comparison drug)
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- University of Glasgow
Diabetes Mellitus Type 2 in Obese, Inflammation
IL-1-receptor Antagonist During Cephalic Phase of Insulin Secretion in Health and Type 2 Diabetes
A prospective, randomized, mixed double- and single-blinded, placebo-controlled, cross-over clinical trial to test whether acute treatment with an IL-1 receptor antagonist impacts insulin secretion over time during the cephalic…
- Conditions
- Diabetes Mellitus Type 2 in Obese, Inflammation, Metabolic Disease, Glucose Metabolism Disorders (Including Diabetes Mellitus)
- Trial name
- Cephalira (NCT04227769)
- Testing
- Anakinra Prefilled Syringe
- Where
- Switzerland
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Glucose Metabolism Disorders (Including Diabetes Mellitus), Lipid Metabolism Disorders
CBD, Nutrient Metabolism and Energy Intake
CBD may affect metabolic control and energy intake. However, there is currently little data regarding these specific outcomes in humans.
- Conditions
- Glucose Metabolism Disorders (Including Diabetes Mellitus), Lipid Metabolism Disorders, Appetitive Behavior
- Trial name
- NCT05618756
- Testing
- Acute oral CBD supplementation
- Where
- United Kingdom
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Loughborough University
13-18 Year, Diagnosed at Least 6 Months Ago
Metabolic Control Adolescents Type 1 Diabetes
Purpose of the research; The aim of this study is to examine the effect of education including peer-interactive group support to be given to adolescents diagnosed with Type 1 diabetes with poor glycemic control in the 13-18 age…
- Conditions
- 13-18 Year, Diagnosed at Least 6 Months Ago, HbA1C> 7.5, Being Able to Read and Write
- Trial name
- NCT05811078
- Testing
- training sessions with peer interactive group
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people
- Sponsor
- Toros University
Glucose Metabolism Disorders (Including Diabetes Mellitus), Cognitive Decline
Glucose Variability and Cognition in Prediabetes
This study examines the association of variability in glucose values over a 10-day period with cognitive function and AD risk markers among individuals with prediabetes, aged 50 or older.
- Conditions
- Glucose Metabolism Disorders (Including Diabetes Mellitus), Cognitive Decline, PreDiabetes, Aging
- Trial name
- NCT04201600
- Testing
- Continuous Glucose Monitoring System (CGMS)
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Obesity, Prehypertension
Weight Inclusive and Adaptive Strategies to Enhance Cardiometabolic Health in Black Adults
The proposed 6-month pilot Sequential Multiple Assignment Randomize Trial (SMART) has two aims. The first and primary aim is to determine the feasibility of conducting a full-scale SMART to compare weight-focused (i.e., weight…
- Conditions
- Obesity, Prehypertension, Hypertension, PreDiabetes
- Trial name
- WISE Health (NCT06284681)
- Testing
- Weight-focused health coaching, Weight-neutral health coaching, Intensify lifestyle approach
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- University of Alabama at Birmingham
Diabetes, Diabetes Mellitus, Type 2
Basal Bolus of Insulin Aspart Including Insulin NPH and Biphasic Insulin Aspart in Type 2 Diabetes
This trial is conducted in Europe and Asia. The aim of this trial is to compare basal bolus treatment with insulin aspart and insulin NPH to biphasic insulin aspart treatment on blood glucose control in type 2 diabetes.
- Trial name
- NCT00600626
- Testing
- biphasic insulin aspart, insulin NPH, insulin aspart
- Where
- 55 sites in Croatia, France and 11 more
- Volunteers
- 394 people
- Sponsor
- Novo Nordisk A/S
Treatment Adherence, Quality of Life
Healthcare Intervention Program on Treatment Adherence in People With Newly Diagnosed Type 2 Diabetes Mellitus.
Type 2 Diabetes Mellitus (T2DM) is a group of metabolic disorders characterized by hyperglycemia in the absence of treatment, positioned in the first places of prevalence and mortality in the Mexican population.
- Conditions
- Treatment Adherence, Quality of Life, Glucose Metabolism Disorders (Including Diabetes Mellitus)
- Trial name
- NCT05719675
- Testing
- Intervention
- Where
- Mexico
- Volunteers
- 24 people
- Sponsor
- Universidad Nacional Autonoma de Mexico
Acute Coronary Syndrome, Diabetes Mellitus, Type 2
Simvastatin and Fenofibrate vs Simvastatin Alone in Patients With Type 2 Diabetes Mellitus and Acute Coronary Syndrome
To test the hypothesis that early (within 5-21 days after index event) administration of combined lipid-lowering therapy in extremely high risk population of patients with type 2 diabetes mellitus (T2DM) and hypertriglyceridemia…
- Conditions
- Acute Coronary Syndrome, Diabetes Mellitus, Type 2, Hypertriglyceridemia
- Trial name
- NCT02015988
- Testing
- Fenofibrate, Simvastatin
- Where
- Ukraine
- Volunteers
- 60 people
- Sponsor
- Koval' O., MD
Glucose Intolerance, Appetite Disorders
Almond Consumption and Glycemia
This study will examine the effects of almonds consumed by adults with different body fat distributions on indices of carbohydrate and lipid metabolism.
- Conditions
- Glucose Intolerance, Appetite Disorders, Glucose Metabolism Disorders (Including Diabetes Mellitus), Lipid Metabolism Disorder
- Trial name
- NCT03236116
- Testing
- Almonds, Control (no nuts)
- Where
- 3 sites in United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Purdue University
Diabetes Mellitus
A Study of DIA:CONN P8 Smart Insulin Pen With CGM-Based Coaching in Patients With Type 1 or Type 2 Diabetes
A Study of DIA:CONN P8 Smart Insulin Pen With CGM-Based Coaching in Patients With Type 1 or Type 2 Diabetes
- Trial name
- NCT07004153
- Testing
- Smart Coaching Insulin Pen
- Where
- South Korea
- Volunteers
- 152 people
- Sponsor
- G2e Co., Ltd
Glucose Metabolism Disorders (Including Diabetes Mellitus), Energy Supply; Deficiency
Effect of Ketogenic Diet on Glucose Metabolism and Energy Expenditure in Type 2 Diabetes
The study team will examine the effect of a ketogenic diet alone and ketogenic diet supplemented with oral ketones on how the body of individuals with type 2 diabetes respond to insulin, regulates insulin secretion, food intake…
- Conditions
- Glucose Metabolism Disorders (Including Diabetes Mellitus), Energy Supply; Deficiency, Type 2 Diabetes
- Trial name
- NCT04791787
- Testing
- Standard weight maintaining diet, Weight maintaining isocaloric ketogenic diet, Beta-hydroxy butyrate
- Where
- 2 sites in United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Disabilities, Obesity and Overweight
Development of an Inclusive Adaptive Treatment Strategy for Weight Loss in People With Prediabetes Using a Sequential Multiple Assignment Randomized Trial
This is a sub-study to NCT04745572 to include a new cohort of participants with disabilities. This 16-week study will use an experimental approach called the Sequential Multiple Assignment Randomized Trial to help determine which…
- Conditions
- Disabilities, Obesity and Overweight, Prediabetes
- Trial name
- iADAPT (NCT06976307)
- Testing
- High Carbohydrate Diet, Reduced Carbohydrate Diet
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Alabama at Birmingham
Diabetes Mellitus
Pharmacokinetic and Pharmacodynamic Properties of BIOD-123 and BIOD-125 Compared to Humalog® in Subjects With Type 1 Diabetes Including Assessments of Injection Site Toleration
The primary objective is to assess the speed of absorption of BIOD-123 and BIOD-125 and compare them to Humalog.
- Trial name
- NCT01908894
- Testing
- BIOD-123, BIOD-125, Humalog
- Volunteers
- 12 people
- Sponsor
- Biodel
Diabetes
A Study of the Continuous Glucose Monitoring System for Home Use in Patients With Diabetes
Subjects in the upper arm group will have a sensor of the CGM System inserted on each arm (left and right upper arm). Subjects in the abdomen group will have 2 sensors inserted, one on each side of the abdomen (left and right…
- Trial name
- NCT04964752
- Testing
- continuous glucose-monitoring
- Volunteers
- 144 people
- Sponsor
- Lee's Pharmaceutical Limited
Metabolic Disease, Insulin Sensitivity
Metabolic Effects of Melatonin Treatment
Modern living is associated with an epidemic of type 2 diabetes mellitus (T2DM). Sleep disturbances such as insomnia or frequent awakenings are strong risk factors for T2DM with several studies indicating a central role of…
- Conditions
- Metabolic Disease, Insulin Sensitivity, Glucose Metabolism Disorders (Including Diabetes Mellitus), Type 2 Diabetes Mellitus
- Trial name
- NCT03859934
- Testing
- Melatonin
- Where
- Denmark
- Volunteers
- 17 people
- Sponsor
- University of Aarhus
Glucose Metabolism Disorders (Including Diabetes Mellitus)
Continuous Glucose Monitoring in Patients Undergoing Cardiopulmonary Bypass
The purpose of this research study is to test the accuracy of the Dexcom continuous glucose monitoring device during the cardiothoracic surgical procedure and recovery period in the Cardiac Intensive Care Unit.
- Trial name
- NCT06861881
- Testing
- Dexcom G7 Continuous Glucose Monitor
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Wake Forest University Health Sciences