Clinical trials: Glucose Variability
Intermittent Fasting
Glycemic Variability in Intermittent Fasting
The aim was to test the difference in glycemic variability after meal consumption during intermittent fasting and the usual diet.
- Trial name
- GLUInterm (NCT05806489)
- Testing
- Intermittent Fasting, Control Diet
- Where
- Croatia
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Josip Juraj Strossmayer University of Osijek
Type 2 Diabetes
Characterization of the Variability of Insulin Secretory Parameters in the Meal Tolerance and the Maximal Stimulation Tests of Healthy Subjects
A multi-year clinical study to improve tools for measuring the function of insulin-producing beta cells in people with type 2 diabetes mellitus.
- Trial name
- NCT01454973
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Foundation for the National Institutes of Health
Diabetes
Distinguishing Patient Groups Using Autonomic Dysfunction
A study population with impaired fasting glucose levels, impaired glucose tolerance levels and diabetes (with or without complications) along with healthy patients will be chosen as participants.
- Trial name
- NCT04964921
- Testing
- Device: ANSiScope Plus
- Volunteers
- healthy volunteers welcome
- Sponsor
- DyAnsys, Inc.
Diabetic Macular Edema
Intra-individual Variability and Circadian Rhythm of VEGF Levels and Interaction With Biomarkers
The study evaluates the intra-individual variability of VEGF levels over a period of 6 months as well as the circadian variation of VEGF levels, both under standardized conditions in patients with type 2 diabetes without DME and…
- Trial name
- NCT02325271
- Testing
- Frequent blood and urine sampling and blood pressure measurement
- Where
- Germany
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- GWT-TUD GmbH
Prediabetes (Insulin Resistance, Impaired Glucose Tolerance), Artificial Intelligence Mobile Application
Food-i-Sense Analytics: Integrating AI Into Continuous Glucose Monitoring Data Analysis for Precision Nutrition.
This study aims to improve how we understand and manage blood sugar responses in adults without diabetes. Even in people who appear healthy, blood sugar levels after meals can behave in different ways.
- Trial name
- Food_i Sense (NCT07626658)
- Testing
- Continuous glucose monitoring using a wearable sensor (flash interstitial glucose monitor)
- Volunteers
- 471 people, healthy volunteers welcome
- Sponsor
- IMDEA Food
Obesity, Severe Obesity
Energy Expenditure From ECAL Indirect Calorimeter in a Multicomponent Weight Management Service
Whether greater weight loss is as a result of a smaller reduction in energy expenditure with caloric restriction is not known. Resting energy expenditure and 24-hour energy expenditure vary substantially between individuals.
- Conditions
- Obesity, Severe Obesity, Sleep Apnoea
- Trial name
- ECAL (NCT03638895)
- Testing
- ECAL Indirect Calorimeter, Diet, exercise & behaviour modification therapy
- Where
- United Kingdom
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- University of Liverpool
Type 2 Diabetes
Exercise as a Tool for Studying the Mechanisms and Applicability of Glycemic Variability
The aim this study is characterize glycemic variability using linear and nonlinear mathematical tools, under basal conditions and in response to specific protocols acute exercise that evoke oxidative stress and inflammation in…
- Trial name
- ETSMAGV (NCT02262208)
- Testing
- Aerobic Exercises, Eccentric Exercise, Continuous glucose monitoring system (Guardian, Medtronic, Northridge, USA)
- Where
- Brazil
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre
Prediabetic State, Obesity
The PRE-D Trial: Effect of Dapagliflozin, Metformin and Physical Activity in Pre-diabetes
The overall objective is to compare the short-term (3 months) effectiveness of three glucose-lowering interventions (dapagliflozin, metformin and physical activity) on glucose variability, body composition, and cardiometabolic…
- Trial name
- NCT02695810
- Testing
- Dapagliflozin, Metformin, Exercise
- Where
- Denmark
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Steno Diabetes Center Copenhagen
Type I Diabetes
Epigenetic Modifications of Diabetes Mellitus Type I
This research is being done to find out if significant changes in blood glucose cause bad outcomes in patients with diabetes.
- Trial name
- NCT01623388
- Testing
- Oral glucose tolerance test for Phase I
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Scripps Translational Science Institute
Glucose Control, Prediabetes (Insulin Resistance, Impaired Glucose Tolerance)
Eating Almonds Before a Meal to Control Blood Sugar
The goal of this study is to learn whether eating a small serving of almonds before meals can improve blood sugar control in adults who have early signs of problems with blood sugar regulation.
- Conditions
- Glucose Control, Prediabetes (Insulin Resistance, Impaired Glucose Tolerance), Precision Medicine, Nutrition
- Trial name
- NUTS (NCT07603739)
- Testing
- Premeal almond ingestion
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Impaired Blood Glucose Level, Overweight
Early Diagnosis of Diabetes Mellitus Type 2 (DM2)
Rationale: The global prevalence of diabetes, along with its devastating effects on life expectancy and quality of life, continues to increase.
- Conditions
- Impaired Blood Glucose Level, Overweight, Obesity
- Trial name
- 7348 (NCT00469287)
- Where
- Netherlands
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- TNO
Infant Conditions, Glucose Intolerance
Monitoring of Postprandial Glycemic Variability in Healthy Young Infants
To measure and quantify the postprandial glucose variations in response to a meal in the healthy 6-12 months old child and correlate this response with the composition of this meal.
- Trial name
- IGVM (NCT03819725)
- Testing
- Glucose monitoring
- Where
- Switzerland
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Lausanne Hospitals
End Stage Liver Disease, Rejection
Study of PD/PK/PG Relationships of Tacrolimus and Cyclosporin in Liver Transplant Patients
To search for suitable pharmacodynamic biomarkers, i.e., with high specificity for calcineurin inhibition and most affected by inter-individual variability, our works aimed at exploring the pharmacodynamics of CNI, the strength…
- Conditions
- End Stage Liver Disease, Rejection, Infection, Malignancy
- Trial name
- 3PIGREF (NCT01760356)
- Where
- Uruguay
- Volunteers
- 141 people, healthy volunteers welcome
- Sponsor
- UDA Centro Nacional Hepato-Bilio-Pancreático
Type 2 Diabetes
Evaluation of CYP450 Activities in Diabetic Patients vs. Non-diabetic Subjects
Type 2 diabetes (T2D) could modulate CYP450 activities involved in drug-metabolism and cardiovascular homeostasis. We propose to carry out, for the first time, a comprehensive characterization of the effects of T2D on the…
- Trial name
- NCT02291666
- Testing
- CRCHUM-MT cocktail
- Where
- Canada
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Postprandial Hyperglycemia, Heart Rate Variability
Effect of Feet and Calf Heating on Glucose Tolerance
Determine the effect of feet and calf heating on glucose tolerance relative to thermoneutral control. Heat will be administered using hot water (40 degrees celsius).
- Trial name
- NCT04232098
- Testing
- Heat to ankle, Heat to calf
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- San Diego State University
Cardiovascular, Diabetic
Exercise and Cardiovascular Control During Upright Tilt in Older Adults With Type 2 Diabetes
Older persons with diabetes have a harder time maintaining blood pressure when standing up. When blood pressure drops when standing up, fainting may occur.
- Trial name
- NCT00387452
- Testing
- Aerobic Exercise and Strength Exercise, Strength training
- Where
- Canada
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Diabetes
Distinguishing Participant Groups Using Autonomic Dysfunction
A study population with impaired fasting glucose levels, impaired glucose tolerance levels and diabetes (with or without complications) along with healthy patients will be chosen as participants.
- Trial name
- NCT05199350
- Testing
- Device Name: ANSiscope
- Where
- India
- Volunteers
- 175 people, healthy volunteers welcome
- Sponsor
- DyAnsys, Inc.