Clinical trials: Gluten-Sensitive Enteropathy
Celiac Disease
Choosing a Preferred Serology Kit for Screening and Diagnosis of Celiac Disease
The investigators will perform prospective observational multicenter study which includes children with suspicion of CD who referred to gastroscopy and intestinal biopsies (study group) and children without suspicion of CD who…
- Trial name
- NCT02805816
- Where
- Israel
- Volunteers
- 128 people
- Sponsor
- Rabin Medical Center
Celiac Disease
Safety and Tolerability of Nexvax2 in Subjects With Celiac Disease
A randomized, double-blind, placebo-controlled, dose titration trial, stratified by Human Leukocyte Antigen (HLA)-DQ2.5 genotype in subjects with celiac disease.
- Trial name
- NCT02528799
- Testing
- Nexvax2
- Where
- 4 sites in Australia, New Zealand
- Volunteers
- 38 people
- Sponsor
- ImmusanT, Inc.
Celiac Disease
Safety and Tolerability of Oat Containing Gluten-free Diet
The purpose of this study is to determine the safety and tolerability of oats in gluten free diet.
- Trial name
- SafeOatDiet (NCT02612766)
- Testing
- Pure, uncontaminated oats
- Where
- Romania
- Volunteers
- 25 people
- Sponsor
- Alfred Rusescu Institute for Mother and Child Care
Celiac Disease, Iron Deficiency
Celiac Disease and Unexplained Iron Deficiency in a Primary Care Setting
The purpose of this study is to determine if patients with unexplained iron deficiency have underlying diseases processes such as celiac disease.
- Conditions
- Celiac Disease, Iron Deficiency, Iron Malabsorption
- Trial name
- NCT02036944
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Providence Medical Research Center
Irritable Bowel Syndrome, Crohn Disease
Effect of UGIR in Adults With Compromised Gut Function and Malabsorption
This study assessed the effect of a nutrition support product on quality of life in adults with compromised gut function and malabsorption.
- Conditions
- Irritable Bowel Syndrome, Crohn Disease, Ulcerative Colitis, Celiac Disease
- Trial name
- NCT03011593
- Testing
- Nutrition Support Product
- Volunteers
- 18 people
- Sponsor
- Metagenics, Inc.
Adult Form of Celiac Disease
Noninvasive Markers of Gluten Ingestion in Celiac Disease Patients
This is a clinical trial to evaluate the sensitivity of noninvasive, novel markers of gluten ingestion in celiac disease patients who are following gluten free diet for at least a period of one year.
- Trial name
- NCT02389062
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Thomas Jefferson University
Celiac Disease, Gluten Sensitivity
Effects of Home Gluten Immunogenic Peptide Testing on Children With Celiac Disease
This study aims to investigate how knowledge of gluten immunogenic peptide (GIP) levels in stool and urine affects subsequent adherence to a gluten-free diet.
- Conditions
- Celiac Disease, Gluten Sensitivity, Gluten Enteropathy, Gastrointestinal Disease
- Trial name
- NCT03462979
- Testing
- Immunochromatographic lateral flow test
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Boston Children's Hospital
Type 1 Diabetes, Celiac Disease
Gluten Immunity and Islet Autoimmunity in Type-1 Diabetes
The purpose of this study is to determine whether the immune response causing celiac disease is related to the autoimmune response causing type-1 diabetes.
- Trial name
- NCT01932476
- Testing
- Gluten Challenge
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Joslin Diabetes Center
Celiac Disease, Healthy
A First-in-human Study to Evaluate the Safety and Tolerability of HB-2121 as a Diagnostic for Celiac Disease
The goal of this clinical trial is to learn about the safety of a single dose of HB-2121 in adults. It will also look at how the body processes the drug.
- Trial name
- NCT07063823
- Testing
- HB-2121
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Nielsen Fernandez-Becker
Celiac Disease, Irritable Bowel Syndrome
Effect of FODMAP Restriction on Persistent GI-symptoms in Coeliac Patients
The first aim of the study is to investigate the prevalence of persistent gastrointestinal symptoms and compliance with gluten-free diet and the intake of FODMAP in adult celiac patients.
- Conditions
- Celiac Disease, Irritable Bowel Syndrome, Diet Modification, Gluten Sensitivity
- Trial name
- NCT03678935
- Testing
- Low FODMAP diet
- Where
- Norway
- Volunteers
- 80 people
- Sponsor
- Oslo University Hospital
Celiac Disease in Children, Pediatric Disorder
Serological Identification of Celiac Disease in Kids
The investigators aim to examine the feasibility of incorporating serological celiac disease (CD) screening into general pediatric outpatient clinics in Sweden and through structured monitoring examine the effects of diagnosing…
- Conditions
- Celiac Disease in Children, Pediatric Disorder, Health, Subjective, Growth Delay
- Trial name
- SICK (NCT03966625)
- Testing
- tissue transglutaminase autoantibodies
- Where
- 2 sites in Sweden
- Volunteers
- 496 people, healthy volunteers welcome
- Sponsor
- Sahlgrenska University Hospital
Weaning Failure
Preventing Celiac Disease by Weaning With Mediterranean Diet
Background: The introduction of solid foods in alignment with the Mediterranean Diet (MD) post-exclusive milk feeding has been demonstrated to cultivate a lasting affinity for healthy eating during infancy and childhood.
- Trial name
- PEMED (NCT06184906)
- Testing
- Weaning by Mediterranean Diet
- Volunteers
- 3,200 people
- Sponsor
- University of Naples
Celiac Disease
Evaluate the Use of Optical Frequency Domain Imaging (OFDI) for Celiac Disease in Children, Adolescents and Young Adults
The goal of this research is to conduct a pilot clinical study to image Celiac disease characteristic mucosal lesions and compare Optical Frequency Domain Imaging (OFDI) images to histologic evaluation in children, adolescents…
- Trial name
- NCT01439035
- Testing
- MGH OFDI Imaging
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Massachusetts General Hospital
Diet, Gluten-Free, Gluten-Sensitive Enteropathy
Non Coeliac Gluten Sensitivity in Children
Irritable Bowel syndrome (IBS) is a very frequent condition in children. Its management is difficult, often resulting in a persistence of chronical abdominal pain.
- Trial name
- NCT02895438
- Testing
- gluten
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Celiac Disease
Coeliac Disease in Spain: Determination of Disease Prevalence and Risk Factors
Previous studies have showed that Coeliac Disease (CD) prevalence is significantly higher in children compared with adults. The largest epidemiologic study carried out in Spain to date (n=4230) reported a higher CD prevalence in…
- Trial name
- NCT05094232
- Where
- Spain
- Volunteers
- 4,826 people, healthy volunteers welcome
- Sponsor
- Hospital Mutua de Terrassa
Unidentified Gastrointestinal Symptoms Following Gluten-free Oats Consumption
Gluten-free Oats and Gastrointestinal Health in Coeliac Disease, Part 2
The research aims to investigate the effects of gluten-free oats to the gastrointestinal health in celiac disease patients and healthy subjects.
- Trial name
- NCT02761785
- Where
- Finland
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University of Turku
Schizophrenia, Gluten Sensitivity
Confirmatory Efficacy Trial of a Gluten-Free Diet in a Subgroup of Persons With Schizophrenia Who Have High Levels of IgG Anti-Gliadin Antibodies (AGA IG)
This study purpose is to conduct a confirmatory double-blind randomized controlled trial in an inpatient setting of the effects of a tightly controlled gluten-free diet (GFD) to improve negative symptoms in people with…
- Conditions
- Schizophrenia, Gluten Sensitivity, Schizo Affective Disorder
- Trial name
- NCT03183609
- Testing
- Gluten Flour in Protein Shake, Rice Flour in Protein Shake
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Maryland, Baltimore
Celiac Disease
Gluten-free Diet Monitoring in Urine
The purpose of this study is to develope a novel method to determine gluten intake and to check gluten-free diet adherence in celiac patients by detection of gluten immunogenic peptides in urine.
- Trial name
- NCT02344758
- Testing
- Non-invasive lateral flow test for monitoring gluten intake, gluten-free diet (GFD), gluten-containing diet
- Where
- Spain
- Volunteers
- 134 people
- Sponsor
- University of Seville
Celiac Disease in Children
Celiac Disease and Diabetes Mellitus
The aim of the present study is to detect Celiac Disease among suspected patients with Type 1 Diabetes Mellitus who admitted to Assiut University Children's Hospital during one year duration
- Trial name
- NCT05442398
- Where
- Egypt
- Volunteers
- 41 people
- Sponsor
- Mohamed Salah Ahmed Ali
Chronic Pain
Radiofrequency Splanchnic Denervation Versus Retrocrural Neurolytic Celiac Block for Pancreatic Cancer Pain
The investigators will evaluate the analgesic efficacy of radiofrequency splanchnic nerve denervation versus neurolytic retrocrural celiac denervation for patients with abdominal pain due to cancer pancreas
- Trial name
- NCT03886298
- Testing
- radiofrequency splanchnic denervation, retrocrural celiac denervation
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University