Clinical trials: Goals
Coronary Artery Disease, Hemodynamic Monitoring
Single Transpulmonary Thermodilution and Continuous Monitoring of Central Venous Oxygen Saturation During Off-pump Coronary Surgery
The aim of the present study was to evaluate the usefulness of an algorithm based on hemodynamic parameters obtained by single transpulmonary thermodilution (STD) combined with continuous monitoring of central venous oxygen…
- Conditions
- Coronary Artery Disease, Hemodynamic Monitoring, Goal Directed Therapy
- Trial name
- OPCAB (NCT00624494)
- Testing
- Conventional monitoring, Advanced monitoring
- Where
- Russia
- Volunteers
- 40 people
- Sponsor
- Northern State Medical University
Caffeine, Affect
Motivational, Affective and Performance Effects of Caffeine Supplementation
The main objective of the study is to evaluate the influence of caffeine intake on participants' energetic arousal, affect, motivation to achieve a training goal, satisfaction with training, and the sense of agency during…
- Conditions
- Caffeine, Affect, Goals
- Trial name
- NCT06321861
- Testing
- Caffeine, No substance
- Where
- Poland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Jagiellonian University
Goal Directed Fluid Therapy
Stroke Volume Variation and Plethysmography Variability Index as Goal Directed Fluid Therapy in Major Oncosurgeries
Patients were allotted to two Groups , SVV Guided Fluid Therapy Group received intraoperative fluids to maintain SVV <11 , and PVI Guided Group received intraoperative Fluids to maintain PVI<11
- Trial name
- SVV PVI GDFT (NCT05142163)
- Testing
- Intraoperative SVV Guided Fluid Therapy, Intraoperative PVI Guided Fluid Therapy
- Where
- India
- Volunteers
- 68 people
- Sponsor
- Rajiv Gandhi Cancer Institute & Research Center, India
Goal-directed Fluid Therapy
Stroke Volume Variation- Guided Hemodynamic Therapy Versus Oxygen Extraction Ratio-guided Hemodynamic Therapy
The FloTrac/Vigileo is a minimal invasive device assessing flow based hemodynamic parameters by pulse contour analysis based on the radial artery pressure signal.
- Trial name
- NCT05487924
- Testing
- SVV-GDHT, O2ER-GDHT, conventional care
- Volunteers
- 610 people
- Sponsor
- Beijing Tongren Hospital
Acquired Brain Injury, Executive Dysfunction
A Single-case Design to Investigate a Compensatory Strategy Game Supporting Goal Management Training
The main cognitive complaint in brain-injured patients is often the everyday disorganization caused by executive function (EF) deficits. In order to minimize the everyday disorganization, effective EF interventions are required.
- Conditions
- Acquired Brain Injury, Executive Dysfunction, Goal Management Training, Compensatory Strategy Training
- Trial name
- NCT05737238
- Testing
- Intervention during phase B: Compensatory brain game supporting Goal Management Training intervention
- Where
- Netherlands
- Volunteers
- 4 people
- Sponsor
- Klimmendaal Revalidatiespecialisten
The Goal of This Trial is to to Compare the Effect of Risperidone vs Aripiprazole in Terms of Change in Serum Glutathione Level
EFFECT OF RISPERIDONE vs ARIPIPRAZOLE ON OXIDATIVE STRESS IN PATIENTS WITH AUTISM SPECTRUM DISORDER: A RANDOMIZED CONTROLLED TRIAL
The goal of this Randomized Controlled Trial is to to compare the effect of Risperidone vs Aripiprazole in terms of change in serum Glutathione level in patients with Autism Spectrum Disorder over a period of 6 weeks.
- Trial name
- versus (NCT05868720)
- Testing
- Risperidone, Aripiprazole
- Volunteers
- 42 people
- Sponsor
- All India Institute of Medical Sciences, Bhubaneswar
Goal-directed Fluid Therapy
Effect of SVV-guided Fluid Therapy on Outcomes After Major Abdominal Surgery
The investigators conduct this randomized assessor-blinded controlled trial to evaluate the effect of SVV-guided fluid therapy on postoperative morbidity and mortality in comparison with conventional fluid therapy after major…
- Trial name
- NCT03940144
- Testing
- the enhanced flow-based hemodynamic parameters of the FloTrac/Vigileo device
- Where
- China
- Volunteers
- 110 people
- Sponsor
- Beijing Tongren Hospital
Cerebral Palsy, Collaborative Intervention Process
Effectiveness of Family-Professional Collaboration on Functional Goals Achievement of Children With Cerebral Palsy and Caregivers' Quality of Life and Burden
The aim of this study is to examine the effect of implanting the family-professional collaboration practice model on the functional goals achievement of children with CP and their caregivers' quality of life and burden.
- Conditions
- Cerebral Palsy, Collaborative Intervention Process, Functional Goals Achievement
- Trial name
- NCT05709080
- Testing
- family-professional collaboration practice model
- Where
- Saudi Arabia
- Volunteers
- 54 people
- Sponsor
- King Saud University
Acute Pain, Atrophic
Neurophysiology of Weakness and Exercise in Rotator Cuff Tendinopathy
The purpose of this study is to examine deficits in activation and motor patterns, as well as central drive in patients with rotator cuff tendinopathy.
- Conditions
- Acute Pain, Atrophic, Goals, Impairment
- Trial name
- NCT02971072
- Testing
- Subacromial injection, Physical Therapy
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University of Oregon
Nociceptive Pain, Goal-directed Therapy
Nol-Index Guided Remifentanil Analgesia Versus Standard Analgesia During Moderate-to-High Risk Cardiovascular Surgery
This study will investigate the potential of guiding remifentanil analgesia during cardiac and vascular surgery in moderate to high risk patients requiring general anesthesia.
- Conditions
- Nociceptive Pain, Goal-directed Therapy, Hemodynamic Instability, Nol-Index
- Trial name
- NCT04137991
- Testing
- Nol-Index guided analgesia, Standard Analgesia
- Where
- Belgium
- Volunteers
- 48 people
- Sponsor
- Erasme University Hospital
Caridac Output-guided Goal-directed Hemodynamic Therapy, Oxygen Delivery
The Effect of Perioperative Cardiac Output-guided GDT on Oxygen Delivery, Consumption, and Microcirculatory Perfusion
Perioperative cardiac output-guided goal-directed therapy (GDT) triggers fluid, vasopressor, and inotrope administration assuming that optimizing cardiac output (i.e., global blood flow) ensures adequate oxygen delivery and…
- Conditions
- Caridac Output-guided Goal-directed Hemodynamic Therapy, Oxygen Delivery, Oxygen Consumption, Microcirculatory Perfusion
- Trial name
- CUSTOM (NCT05090254)
- Testing
- Treatment algorithms targeting cardiac output
- Where
- Germany
- Volunteers
- 78 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Goals
Engaging Patients in Mutual Goal-Setting in Hospitalized Patients
Mutual goal setting and action planning in patients with long-term conditions in outpatient settings is associated with favorable effects on measures of physical health, psychological health, subjective health status…
- Trial name
- NCT04977206
- Testing
- Mutual Goal-Setting Education
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Marquette University
Physical Activity, Behavior
WalkIT Arizona: Walking Interventions Through Texting
The purpose of this study is to develop adaptive (AI) and micro-incentive (MI) interventions and test them against static (SI) and delayed-incentive (DI) interventions in a 4-arm randomized factorial trial to increase MVPA…
- Conditions
- Physical Activity, Behavior, Goals
- Trial name
- NCT02717663
- Testing
- Adaptive Goals, Static Goals, Delayed (non-contingent) Incentives
- Where
- United States
- Volunteers
- 512 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Goal Directed Therapy, Fluid Therapy
Goal Directed Therapy Versus Standard Care in Lung Resection Surgery (GDT-thorax Study).
The primary aim of this study is to quantify and compare the hemodynamic control of cardiac index in patients who receive either goal-directed therapy or standard hemodynamic management in lung resection surgery
- Trial name
- GDT-thorax (NCT03245372)
- Testing
- Standard care, Goal directed therapy
- Where
- Spain
- Volunteers
- 31 people
- Sponsor
- Fundación Pública Andaluza para la gestión de la Investigación en Sevilla
Goal Directed Therapy, Postoperative Complications
Feasibility of Extended Non-invasive Haemodynamic Monitoring in the PACU
Post-operative monitoring of all patients after anaesthesia in the post anaesthesia care unit (PACU) is standard of care today. It helps to reduce morbidity and even mortality in high-risk patients.
- Conditions
- Goal Directed Therapy, Postoperative Complications, Complications, Ultrasound Therapy
- Trial name
- NCT04814966
- Where
- Germany
- Volunteers
- 80 people
- Sponsor
- University Hospital Schleswig-Holstein
Development, Human, Well-Being
The Impact of Professional Coaching on Early Career Academic Emergency Physicians
This research study is designed to answer the question: How does professional coaching impact early career academic emergency medicine physician goal attainment, leadership strengths, well-being, and burnout?
- Conditions
- Development, Human, Well-Being, Professional Burnout, Goals
- Trial name
- NCT03125330
- Testing
- Professional coaching
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Goal-Directed Fluid Therapy, Hemodynamic Monitoring
Comparison of Goal-directed and Liberal Fluid Management
Background: The investigators aim is to indicate that the "goal directed fluid management" is more effective for open abdominal surgeries by performing perioperative hemodynamic monitorisation using a minimal invasive pulse…
- Conditions
- Goal-Directed Fluid Therapy, Hemodynamic Monitoring, Fluid Management
- Trial name
- NCT04265014
- Testing
- Goal-directed fluid treatment, Liberal Fluid Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- healthy volunteers welcome
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Goal-directed Fluid Therapy
Goal Directed Fluid Therapy Guided Fluid Management in Pneumoresection
Perioperative fluid management is a key component of anesthetic management during thoracic surgery. On one hand, fluid restriction could compromise perfusion of vital organs and surgical anastomosis.
- Trial name
- NCT03237351
- Testing
- Fluid therapy
- Where
- China
- Volunteers
- 60 people
- Sponsor
- ZhiHeng Liu
Chronic Disease, Goals
Effectiveness of a Personalized Health Profile on Specificity of Self-Management Goals
With a growing number of people living with chronic diseases, the need to empower people for self-management is rising. A key element in self-management is goal setting but the extent to which meaningful actionable goals (i.e.…
- Trial name
- NCT04175795
- Testing
- My Personal Brain Health Dashboard
- Where
- Canada
- Volunteers
- 420 people
- Sponsor
- McGill University
Decision Making, Resuscitation
Evaluation of a Decision Aid About Life-sustaining Therapies
Introduction: Clinical practice guidelines recommend shared decision making (SDM) to facilitate goals-of-care discussions. This study will train clinicians about how to use a context-adapted decision aid (DA) and SDM to conduct…
- Conditions
- Decision Making, Resuscitation, Intensive Care Unit, Goals-of-care
- Trial name
- NCT04034979
- Testing
- decision aid
- Where
- Canada
- Volunteers
- 26 people
- Sponsor
- Laval University