Clinical trials: Grass Pollen Allergy
Allergic Rhinitis, Allergic Rhinitis Due to Grass Pollen
Study to Assess the Safety, Tolerability, and Preliminary Efficacy of B244 in Healthy Volunteers and Subjects With Seasonal Allergic Rhinitis
This is a Prospective, Controlled, Double Blinded, Single Center, Randomized, 3 Arm, Parallel Assignment, Phase 1b/2a Study to assess the safety, tolerability, and preliminary efficacy of B244 delivered as an intranasal spray in…
- Conditions
- Allergic Rhinitis, Allergic Rhinitis Due to Grass Pollen, Healthy Volunteers
- Trial name
- NCT03290248
- Testing
- B244 suspension, Vehicle
- Where
- 2 sites in United States, Canada
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- AOBiome LLC
Seasonal Allergy
Efficacy of 2LALERG (Homeopathic Drug) in Allergic Rhinitis Related to Grass Pollen
The primary objective of this study is to demonstrate the superiority of 2L®ALERG over placebo in terms of efficacy on the symptoms of allergic rhinitis and allergic rhinoconjunctivitis in patients with seasonal allergy to grass…
- Trial name
- LLB-2016-01 (NCT02690935)
- Testing
- 2LALERG
- Where
- Belgium
- Volunteers
- 102 people
- Sponsor
- Labo'Life
Hay Fever
Clinical Efficacy and Safety of a Subcutaneous Immunotherapy With gpASIT+™ in Patients With Grass Pollen-induced Allergic Rhinoconjunctivitis
gpASIT+TM product is based on highly purified allergen fragments obtained from grass pollen. The purpose of this study is to demonstrate the clinical efficacy and safety of a subcutaneous immunotherapy with gpASIT+™ in patients…
- Trial name
- NCT02560948
- Testing
- gpASIT+TM
- Where
- 3 sites in Belgium, Italy and 1 more
- Volunteers
- 554 people
- Sponsor
- BioTech Tools S.A.
Seasonal Allergic Rhinitis
Efficacy and Safety of Sublingual Tablets of Grass Pollen Allergen Extract
The objective of this study is to assess the effect of grass pollen extract SLIT tablets on the Rhinoconjunctivitis Total Symptom Score (RTSS) of the six rhinoconjunctivitis symptoms in response to grass pollen challenge after…
- Trial name
- NCT00619827
- Testing
- 300 IR grass pollen allergen extract tablet
- Where
- Austria
- Volunteers
- 89 people
- Sponsor
- Stallergenes Greer
Treatment of the Signs and Symptoms of Seasonal Allergic Rhinitis
A Comparison of Mometasone Nasal Spray, Nasonex Nasal Spray, Nasonex Nasal Spray Suspension, & Placebo for Treatment of Seasonal Allergies for Safety, Efficacy, & Superiority in 1520 Male & Female Volunteers
The study will compare the safety and efficacy of a generic mometasone nasal spray to the reference listed drugs in the treatment of seasonal allergic rhinitis.
- Trial name
- NCT02109185
- Testing
- Mometasone Furoate Monohydrate Nasal Spray, 50 μg/act., Nasonex® Nasal Spray, 50 μg/actuation, Nasonex® Nasal Spray Suspnsn, 50 μg/actuation
- Volunteers
- 1,307 people
- Sponsor
- Mylan Pharmaceuticals Inc
Allergic Rhinitis, Allergic Rhinoconjunctivitis
Demonstration of an Anti-allergic Effect in Subjects Treated With Callergin Nasal Spray in Comparison to Untreated Subjects and Subjects Treated With Vis Alpin® Alpensalz Nasal Spray, All Suffering From Grass Pollen Induced Rhinitis/Rhinoconjunctivitis
Allergic rhinitis (AR) in its seasonal and perennial form is a common allergic condition. The majority of allergic rhinitis sufferers report nasal (congestion, sneezing, itching and rhinorrhea) and ocular (redness, watery eyes…
- Trial name
- NCT04531358
- Testing
- nasal spray, no treatment
- Where
- Austria
- Volunteers
- 42 people
- Sponsor
- Marinomed Biotech AG
Allergic Rhinoconjunctivitis
Multicenter Trial of Sublingual Immunotherapy With a Solution of Grass Pollen Allergen Extract in Children
Evaluation of safety and efficacy of sublingual immunotherapy with grass pollen allergens formulated as solution in comparison to a symptomatic standard treatment with add on placebo in grass pollen allergic children suffering…
- Trial name
- NCT00841256
- Testing
- Grass pollen allergens in a water/glycerol solution
- Where
- Germany
- Volunteers
- 207 people
- Sponsor
- Allergopharma GmbH & Co. KG
Type I-Allergy
Dose-Response-Study With a Recombinant Cocktail of Phleum (rPhleum) Allergens
Dose-response trial with a cocktail of recombinant major allergens of Timothy Grass Pollen (Phleum pratense)
- Trial name
- NCT00666341
- Testing
- rPhleum
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Allergopharma GmbH & Co. KG
Type I Allergy
Design of Optimally-diagnostic Skin Test Solutions for Diagnosis of Sensitisation to a Pollen and Dust Mite Mixture.
Multicenter Skin Prick Test
- Trial name
- NCT00665483
- Testing
- Skin Prick Test
- Where
- Germany
- Sponsor
- Allergopharma GmbH & Co. KG
Grass Pollen Allergy
Safety and Efficacy of Grass Pollen Allergoid in the Treatment of Allergic Rhinoconjunctivitis
The trial is performed to assess efficacy and safety of the Grass Pollen Allergoid in Allergic Rhinoconjunctivitis
- Trial name
- NCT00263601
- Testing
- Allergovit 6-grasses
- Where
- Germany
- Volunteers
- 154 people
- Sponsor
- Allergopharma GmbH & Co. KG
Allergic Rhinitis, Allergic Rhinoconjunctivitis
Efficacy and Safety of SUBLIVAC Phleum for Immunotherapy of Grass Pollen-Allergy
The purpose of this study is to assess safety, tolerability and demonstrate a dose response signal using Total Symptom Score (TSS), based on challenges with grass pollen in an Environmental Exposure Chamber (EEC), followed by…
- Trial name
- NCT02556801
- Testing
- SUBLIVAC FIX Phleum Prat.
- Where
- Canada
- Volunteers
- 168 people
- Sponsor
- HAL Allergy
Seasonal Allergic Rhinitis
Immune-modulatory Effect of Probiotic Strain on Grass Pollen Allergic Individuals
The purpose of the current study is to evaluate the effect of administering a probiotic strain on allergic symptoms and immune parameters (Th-2 cytokines, effector cells) in seasonal allergic rhinitis subjects.
- Trial name
- NCT01660698
- Testing
- Maltodextrin, Probiotic
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- Société des Produits Nestlé (SPN)
Type I Hypersensitivity
Induction of Immunogenicity With Different Doses of Grass MATA in Subjects Allergic to Grass and Rye Pollen
Grass MATA (modified pollen allergen tyrosine adsorbate) has been developed to provide pre-seasonal specific immunotherapy for patients with hypersensitivity to grass and rye pollen.
- Trial name
- NCT00104377
- Testing
- Grass MATA MPL
- Where
- 11 sites in United States
- Volunteers
- 70 people
- Sponsor
- Allergy Therapeutics
Seasonal Allergic Rhinitis, Rhinoconjunctivitis
Efficacy and Safety of PQ Grass in Subjects With Seasonal Allergic Rhinitis and/or Rhinoconjunctivitis Induced by Grass Pollen
The PQGrass306 (G306) clinical trial is the pivotal Phase III efficacy clinical trial of PQ Grass. The aim of the G306 pivotal clinical trial is to confirm the efficacy and safety of the optimal effective dose of PQ Grass 27600…
- Trial name
- NCT05540717
- Testing
- PQ Grass
- Where
- 102 sites in United States, Austria and 4 more
- Volunteers
- 555 people
- Sponsor
- Allergy Therapeutics
Allergy
Safety and Efficacy of Sublingual Immunotherapy (SLIT) Tablets in Grass Pollen Rhinoconjunctivitis
To evaluate the safety and efficacy of SLIT compared with placebo for reduction of symptoms and rescue medication usage
- Trial name
- NCT00367640
- Testing
- 100 IR grass pollen allergen extract tablet, 300 IR grass pollen allergen extract tablet, 500 IR grass pollen allergen extract tablet
- Volunteers
- 628 people
- Sponsor
- Stallergenes Greer
Seasonal Allergic Rhinitis
Study Immunology and Safety of 60-day Treatment of SQ Grass SLIT (Sublingual Immunotherapy)-Tablet in Adult Subjects With Grass Pollen-induced Allergic Rhinoconjunctivitis
To investigate the immunologic effects and safety of 60-day treatment of the Standardized Quality units (SQ) grass Sublingual immunotherapy (SLIT)-tablet in adult subjects with grass pollen-induced allergic rhinoconjunctivitis in…
- Trial name
- NCT02245360
- Testing
- Phleum pratense grass pollen allergen extract
- Where
- 15 sites in Russia
- Volunteers
- 107 people
- Sponsor
- Abbott
Allergic Rhinitis
Efficacy and Tolerability of a Topical Microemulsion in Patients With Allergic Rhinitis Due to Sensitization to Pollen
Study design: Randomized, controlled, double-blind, parallel, multicentre multinational clinical trial, to show superiority of an active therapy as compared to a control therapy on intermittent or persistent Allergic Rhinitis.
- Trial name
- NCT01478425
- Testing
- Lipidic Microemulsion, Saline
- Where
- 9 sites in Spain, Sweden
- Volunteers
- 110 people
- Sponsor
- Reig Jofre Group
Rhinoconjuntivitis
A Trial With Subcutaneous Immunotherapy (SCIT) in Patients With Rhinoconjunctivitis Sensitized to Olea Europaea and Phleum Pratense
The study was designed according to the draft of allergenic product regulation published by Spanish Regulatory Agency. The aim of the study is to evaluate the safety and tolerability of subcutaneous immunotherapy with polimerized…
- Trial name
- NCT02849249
- Testing
- allergovac polimerized (100/100)
- Where
- 5 sites in Spain
- Volunteers
- 52 people
- Sponsor
- Roxall Medicina España S.A
Hypersensitivity
Skin Test Study of BM32
The aim of the present skin test study CS-BM32-001 is to evaluate whether the BM32 proteins exhibit low/no allergenic activity when applied by skin prick- and atopy patch testing to grass pollen allergic patients
- Trial name
- NCT01350635
- Testing
- BM32
- Where
- Austria
- Volunteers
- 60 people
- Sponsor
- Biomay AG
Dermatitis, Atopic
Prevention of Asthma With Levocetirizine 18 Month Treatment in Infants (12 - 24 Months) Suffering From Eczema (Atopic Dermatitis) and Sensitized to Grass Pollen and/or House Dust Mite (HDM)
The Early Prevention of Asthma in Atopic Children (EPAAC™). 24 months study to evaluate the efficacy and safety of levocetirizine (LCTZ) in preventing the onset of asthma in 12 to 24 months old children.
- Trial name
- NCT00152464
- Testing
- Levocetirizine
- Volunteers
- 514 people
- Sponsor
- UCB Pharma SA